roxy mucolite 150 mg/30 mg tablet - Roxithromycin (150mg) + Ambroxol (30mg) medicine

Arbid A 150 Mg/30 Mg Tablet: Complete Medicine Guide

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🏭 Dr Reddy's Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe diarrhea with blood or mucus

If experiencing severe symptoms, call emergency services immediately.

What is roxy mucolite 150 mg/30 mg tablet used for?

This medicine is a combination of Roxithromycin (an antibiotic) and Ambroxol (a mucolytic) used to treat bacterial respiratory infections with thick mucus. It is taken orally, usually twice daily, and must be completed as prescribed.

  • Generic Name: Roxithromycin (150mg) + Ambroxol (30mg)
  • Manufacturer: Dr Reddy's Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 roxy mucolite 150 mg/30 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा रॉक्सिथ्रोमाइसिन और एम्ब्रोक्सोल का संयोजन है। यह बैक्टीरियल श्वसन संक्रमण जैसे ब्रोंकाइटिस, निमोनिया और साइनसाइटिस के इलाज में उपयोग की जाती है। रॉक्सिथ्रोमाइसिन बैक्टीरिया को मारता है और एम्ब्रोक्सोल बलगम को पतला करके बाहर निकालने में मदद करता है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द और स्वाद में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लीवर की समस्या, या दिल की धड़कन में गड़बड़ी हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और पूरा कोर्स पूरा करें। इसे भोजन के साथ लें ताकि पेट की जलन कम हो। शराब न पिएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। इसे बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 roxy mucolite 150 mg/30 mg tablet Uses & Benefits

[{"condition":"Acute bacterial bronchitis","description":"Used to treat bacterial infection of the bronchi, often with thick mucus production.","evidence":"Well-established"},{"condition":"Bacterial pneumonia","description":"Prescribed for community-acquired pneumonia caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Chronic bronchitis exacerbation","description":"Helps manage flare-ups of chronic bronchitis with increased mucus.","evidence":"Well-established"},{"condition":"Upper respiratory tract infections","description":"May be used for bacterial pharyngitis, tonsillitis, or sinusitis when appropriate.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Atypical mycobacterial infections","description":"Roxithromycin has been used off-label for certain atypical mycobacterial infections, but this is not a standard use.","evidence":"Limited"}]

Primary treatment for: Bacterial respiratory tract infections

Also treats: Acute bronchitis, Bacterial pneumonia, Chronic bronchitis exacerbation, Sinusitis

📋 Drug Information

Generic Name(s)Roxithromycin (150mg) + Ambroxol (30mg)
Brand Nameroxy mucolite 150 mg/30 mg tablet
ManufacturerDr Reddy's Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full course as prescribed, even if you feel better.
3
Avoid alcohol while taking this medicine.
4
Do not take antacids within 2 hours of this medicine.
5
Inform your doctor if you have liver or kidney problems.
6
Report any unusual bleeding, bruising, or yellowing of eyes immediately.
7
Use backup contraception if you are on oral contraceptives.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Chest congestion
Ambroxol helps clear mucus.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRoxithromycin is absorbed from the gastrointestinal tract, with bioavailability around 50% when taken on an empty stomach. Food may slightly reduce absorption. Ambroxol is rapidly absorbed after oral administration.
DistributionRoxithromycin distributes widely into body tissues, including lung tissue, where it reaches higher concentrations than in plasma. Ambroxol also distributes into lung tissue and bronchial secretions.
Protein BindingRoxithromycin is about 96% bound to plasma proteins. Ambroxol is approximately 90% bound to plasma proteins.
MetabolismRoxithromycin is metabolized in the liver, primarily by CYP3A4, to several metabolites. Ambroxol is metabolized in the liver by conjugation.
Half-LifeThe elimination half-life of Roxithromycin is approximately 10 to 12 hours. Ambroxol has a half-life of about 7 to 12 hours.
ExcretionRoxithromycin is excreted mainly in feces via bile, with a smaller amount in urine. Ambroxol is excreted in urine as metabolites.
BioavailabilityRoxithromycin bioavailability is about 50% to 55%. Ambroxol bioavailability is approximately 70% to 80%.
Onset of ActionRoxithromycin starts working within a few hours, but noticeable improvement in infection symptoms may take 1 to 2 days. Ambroxol's mucolytic effect begins within 30 to 60 minutes.
Peak Plasma TimeRoxithromycin reaches peak plasma levels about 1.5 to 2 hours after oral intake. Ambroxol peaks at about 1 to 2 hours.
Duration of ActionRoxithromycin's antibacterial effect lasts for about 12 to 24 hours per dose. Ambroxol's mucolytic effect lasts for about 6 to 8 hours.

How It Works

Roxithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing the translocation step needed for peptide chain elongation. This stops bacteria from making essential proteins, leading to their death or growth inhibition. Ambroxol increases serous bronchial secretion, reduces mucus viscosity, and stimulates surfactant production, which helps clear mucus from the airways. It also has mild local anesthetic and antioxidant properties.

Mechanism Steps

1
Roxithromycin binds to 50S ribosomal subunit: Roxithromycin attaches to the bacterial 50S ribosomal subunit, blocking the exit tunnel for newly formed proteins.
2
Inhibition of protein synthesis: This binding prevents the elongation of peptide chains, stopping bacterial protein production and inhibiting bacterial growth.
3
Ambroxol thins mucus: Ambroxol increases the volume and reduces the viscosity of bronchial secretions, making mucus easier to cough out.
4
Enhanced mucociliary clearance: Ambroxol stimulates ciliary movement and surfactant production, helping to clear the airways.

💡 How to Take roxy mucolite 150 mg/30 mg tablet

Strength: Each immediate-release tablet contains Roxithromycin 150 mg and Ambroxol 30 mg.

1Take the tablet with a full glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced times as prescribed.
5Do not skip doses or stop early.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally twice daily, or as prescribed by your doctor. The exact dose and duration depend on the type and severity of infection, your age, weight, kidney and liver function, and other medicines you take. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be needed based on kidney and liver function. Consult your doctor.
Renal ImpairmentDose adjustment may be required in patients with severe kidney impairment. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose adjustment may be needed. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 300 mg of Roxithromycin and 60 mg of Ambroxol, but this must be confirmed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of roxy mucolite 150 mg/30 mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or contains blood, seek medical advice.
Stomach pain (Common (5-10%))
Take with meals. If pain is severe, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent.
Altered taste (Common (5-10%))
Usually temporary. Drink plenty of water.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you notice swelling of face, lips, throat, or difficulty breathing.
Liver injury (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain immediately.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Seek medical help if you develop severe, persistent diarrhea, especially with blood or mucus.
Heart rhythm abnormalities (QT prolongation) (Rare (<0.1%))
Report palpitations, dizziness, or fainting to your doctor immediately.

⚠️ Rare Side Effects

Severe skin reactions (Stevens-Johnson syndrome)
Seek emergency care if you develop a painful rash with blisters or peeling skin.
Pancreatitis
Seek immediate care for severe upper abdominal pain radiating to the back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ergotamine Major
Terfenadine Major
Carbamazepine Moderate
Digoxin Moderate
Theophylline Moderate
Midazolam Moderate
Antacids Minor
Oral contraceptives Minor

🚨 Major Interactions

  • Ergot alkaloids (e.g., ergotamine)
  • Terfenadine, astemizole, cisapride
  • Warfarin

⚡ Moderate Interactions

  • Carbamazepine
  • Digoxin
  • Theophylline
  • Midazolam

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the risk of stomach irritation, liver problems, and may worsen side effects like dizziness or drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Allergy to Roxithromycin, Ambroxol, or other macrolide antibiotics","Severe liver disease","Concurrent use with ergot alkaloids, terfenadine, astemizole, or cisapride","History of QT prolongation or ventricular arrhythmias"]

⚠️ Warnings & Precautions

["Use with caution in patients with liver or kidney disease.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use for viral infections like the common cold.","Complete the full course as prescribed to prevent resistance.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid alcohol during treatment.","May interact with many medicines; always inform your doctor about all medicines you take."]

🤱 Lactation Safety

Roxithromycin and Ambroxol may pass into breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, diarrhea, and stomach pain. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better, because that can allow the infection to return and lead to antibiotic resistance. Take the tablet with a full glass of water, preferably with food to reduce stomach upset. Avoid alcohol while taking this medicine because it can increase the risk of stomach irritation and liver problems. Do not take antacids or other medicines without consulting your doctor, as they may affect how this medicine works. If you have liver or kidney problems, tell your doctor before starting this medicine. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more prone to side effects like dizziness and heart rhythm changes. Dose adjustment may be needed based on kidney and liver function.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. Roxithromycin is generally considered acceptable when clearly needed, but Ambroxol is not recommended in the first trimester.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine before surgery. It may interact with anesthetics and other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with certain antibiotics used in dentistry.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to ease breathing.
😴
Avoid smoking and secondhand smoke.
💧
Get plenty of rest to support recovery.
🧘
Wash hands frequently to prevent spread of infection.

🏋️ Exercise Considerations

Rest during the acute phase of infection. Gradually resume light activities as you feel better. Avoid strenuous exercise until fully recovered.

🥗 Diet Recommendations

Drink warm fluids like soups and herbal teas.
Include vitamin C rich fruits.
Avoid cold and processed foods.
Eat light, easily digestible meals.

💼 Impact on Daily Work & Life

You may feel tired or dizzy; avoid driving or operating heavy machinery until you know how this medicine affects you. Take rest as needed.

🛑 When to Stop This Medicine

Stop only after completing the full prescribed course. If you experience severe side effects, contact your doctor before stopping.

📅 Long-Term Use Effects

Long-term use of antibiotics can lead to antibiotic resistance and disruption of normal gut flora. Roxithromycin may rarely affect liver function. Use only as prescribed and for the recommended duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and ease breathing.

Evidence: Well-established
Saline nasal irrigation

Can help clear nasal congestion.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, antibiotics may reduce the effectiveness of live bacterial vaccines like typhoid. Consult your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with acute bronchitis
Started this medicine as prescribed for a bacterial chest infection with thick mucus. Within 3 days, cough and chest congestion improved significantly. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old with chronic bronchitis flare-up
Prescribed this medicine for a flare-up. Noticed easier breathing and less mucus after 2 days. Reminded to complete the full course to prevent recurrence.
💡 Lesson: Completing the full antibiotic course is essential to prevent resistance and relapse.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1 to 2 days, but complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, take it with food to reduce stomach upset.

Q: Is it safe in pregnancy?

A: Consult your doctor. Roxithromycin is generally considered acceptable when clearly needed, but Ambroxol is not recommended in the first trimester.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for roxy mucolite 150 mg/30 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: It is an antibiotic and does not work against viral infections like the common cold.
  • Myth: You can stop taking it once you feel better.
    Fact: You must complete the full course to prevent the infection from returning and to avoid antibiotic resistance.

🔄 Alternative Options

Generic Alternatives

  • Roxithromycin 150 mg + Ambroxol 30 mg tablet

Brand Alternatives

  • Arbid A 150 mg/30 mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Roxithromycin + Ambroxol","composition":"Roxithromycin 150 mg + Ambroxol 30 mg","class":"Macrolide antibiotic + Mucolytic","usual_dose":"Twice daily","notes":"This medicine"},{"medicine":"Azithromycin + Ambroxol","composition":"Azithromycin 250 mg + Ambroxol 30 mg","class":"Macrolide antibiotic + Mucolytic","usual_dose":"Once daily","notes":"Similar use, different antibiotic"}]

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