Azuvas 10-Gold Capsule: A Comprehensive Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unexplained muscle pain or weakness
- Dark-colored urine
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is rosze gold 10 capsule used for?
This medicine is a prescription combination of Aspirin 75 mg and Rosuvastatin 10 mg used to prevent heart attacks and strokes in high-risk patients. It works by reducing blood clot formation and lowering cholesterol. It is taken once daily with food, and regular monitoring of liver, kidney, and lipid levels is required.
- Generic Name: Aspirin (75mg) + Rosuvastatin (10mg)
- Manufacturer: Zeelab Pharmacy Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 rosze gold 10 capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एस्पिरिन 75 मिलीग्राम और रोसुवास्टेटिन 10 मिलीग्राम का संयोजन है। इसका उपयोग हृदयाघात और स्ट्रोक के जोखिम को कम करने के लिए किया जाता है, विशेष रूप से उन रोगियों में जिन्हें हृदय रोग या उच्च कोलेस्ट्रॉल है। यह रक्त के थक्के बनने को रोकती है और कोलेस्ट्रॉल के स्तर को कम करती है। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे भोजन के साथ लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में अपच, पेट में जलन, मतली, सिरदर्द, मांसपेशियों में दर्द और लीवर एंजाइम में मामूली वृद्धि शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, अल्सर, मांसपेशियों का टूटना (रैब्डोमायोलिसिस), लीवर की क्षति और एलर्जी प्रतिक्रियाएं शामिल हैं। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, मांसपेशियों में असहनीय दर्द या पेशाब का रंग गहरा होना जैसे लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। शराब का सेवन न करें क्योंकि इससे रक्तस्राव और लीवर की समस्या का खतरा बढ़ सकता है। अपने डॉक्टर को अन्य सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। नियमित रूप से लीवर, किडनी, शुगर और लिपिड प्रोफाइल की जांच कराएं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो इस दवा को बिना डॉक्टर की सलाह के न लें।
💊 rosze gold 10 capsule Uses & Benefits
[{"condition":"Secondary prevention of cardiovascular events","description":"Used in patients with established coronary artery disease, cerebrovascular disease, or peripheral arterial disease to reduce the risk of heart attack, stroke, and cardiovascular death.","evidence":"Well-established"},{"condition":"Primary prevention in high-risk individuals","description":"May be prescribed for patients with multiple risk factors such as diabetes, hypertension, smoking, and dyslipidemia who are at high risk of cardiovascular events.","evidence":"Established"},{"condition":"Hypercholesterolemia","description":"Rosuvastatin component effectively lowers LDL cholesterol and triglycerides while increasing HDL cholesterol in patients with primary hypercholesterolemia.","evidence":"Well-established"},{"condition":"Acute coronary syndrome","description":"Aspirin is part of standard therapy in acute coronary syndrome to prevent further thrombotic events, while rosuvastatin helps stabilize plaques and lower cholesterol.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of preeclampsia","description":"Low-dose aspirin is sometimes used off-label in pregnant women at high risk of preeclampsia, but this combination with rosuvastatin is contraindicated in pregnancy.","evidence":"Limited"},{"condition":"Antiphospholipid syndrome","description":"Aspirin may be used off-label for thromboprophylaxis in antiphospholipid syndrome, but rosuvastatin is not standard.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease prevention and hypercholesterolemia
Also treats: Coronary artery disease, Stroke prevention, Peripheral arterial disease, Diabetes with high cardiovascular risk
📋 Drug Information
| Generic Name(s) | Aspirin (75mg) + Rosuvastatin (10mg) |
| Brand Name | rosze gold 10 capsule |
| Manufacturer | Zeelab Pharmacy Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the capsule in its original container, tightly closed. Protect from light and moisture. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Aspirin irreversibly acetylates cyclooxygenase-1 (COX-1) in platelets, inhibiting thromboxane A2 synthesis and thereby reducing platelet aggregation. Rosuvastatin selectively inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate, a rate-limiting step in cholesterol biosynthesis. This inhibition leads to upregulation of LDL receptors on hepatocytes, increasing clearance of LDL cholesterol from the bloodstream and reducing plasma cholesterol levels.
Mechanism Steps
💡 How to Take rosze gold 10 capsule
Strength: Capsule containing Aspirin 75 mg and Rosuvastatin 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule taken orally once daily, preferably with food. The dose may be adjusted by the doctor based on the patient's lipid levels, cardiovascular risk, and tolerability. The maximum recommended dose of rosuvastatin in this combination is 10 mg per day, but higher doses of rosuvastatin may be used separately. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, particularly the risk of gastrointestinal bleeding and muscle toxicity. The dose should be individualized by a clinician, and renal and hepatic function should be monitored. No specific dose adjustment is recommended solely based on age, but caution is advised. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually necessary. However, in severe renal impairment (creatinine clearance <30 mL/min), rosuvastatin should be used with caution, and a lower starting dose may be considered. Aspirin should be avoided in severe renal impairment due to increased risk of bleeding and worsening renal function. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | This medicine is contraindicated in patients with active liver disease or unexplained persistent elevations of serum transaminases. In patients with mild to moderate hepatic impairment, rosuvastatin should be used with caution, and a lower dose may be considered. Aspirin should be avoided in severe hepatic impairment due to risk of bleeding and encephalopathy. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose of this specific combination is one capsule (Aspirin 75 mg + Rosuvastatin 10 mg) per day. Higher doses of individual components may be prescribed separately by a clinician, but this fixed-dose combination should not be exceeded. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of rosze gold 10 capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| NSAIDs | Major | |
| Cyclosporine | Major | |
| Gemfibrozil | Major | |
| Clopidogrel | Moderate | |
| Methotrexate | Moderate | |
| Fibrates | Moderate | |
| ACE inhibitors | Moderate | |
| Antacids | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Warfarin
- Other anticoagulants (e.g., apixaban, rivaroxaban)
- NSAIDs (e.g., ibuprofen, naproxen)
- Cyclosporine
- Gemfibrozil
⚡ Moderate Interactions
- Clopidogrel
- Methotrexate
- Probenecid
- ACE inhibitors
- Fibrates (e.g., fenofibrate)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding due to aspirin's antiplatelet effect and can worsen liver toxicity from rosuvastatin. It may also increase the risk of muscle-related side effects. If you consume alcohol, discuss safe limits with your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to aspirin, rosuvastatin, or any component of the formulation","Active peptic ulcer or history of recurrent peptic ulcer","Active bleeding or bleeding disorders (e.g., hemophilia, thrombocytopenia)","Severe liver disease or unexplained persistent elevations in liver enzymes","Pregnancy and breastfeeding","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Aspirin can cause gastrointestinal bleeding, which may be severe and potentially fatal. Monitor for signs of bleeding.","Rosuvastatin can cause myopathy and rhabdomyolysis. Advise patients to report unexplained muscle pain, tenderness, or weakness.","Liver enzyme elevations can occur with rosuvastatin. Perform liver function tests before and during therapy.","Aspirin may precipitate bronchospasm in patients with asthma, nasal polyps, or aspirin sensitivity.","Rosuvastatin may increase blood glucose levels and risk of diabetes. Monitor glucose in at-risk patients.","Avoid alcohol consumption as it increases risk of liver and gastrointestinal side effects.","Use with caution in elderly patients due to increased risk of bleeding and muscle toxicity.","Do not use in children or adolescents except under specialist care.","Inform patients about the signs of bleeding and the need to seek immediate medical attention.","Discontinue before major surgery due to bleeding risk; consult surgeon."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding. Aspirin and rosuvastatin may pass into breast milk and could cause serious adverse reactions in the nursing infant. A decision should be made whether to discontinue nursing or the medicine, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose of this medicine may cause salicylate toxicity (tinnitus, hyperventilation, metabolic acidosis, hypoglycemia, coma) and statin-related muscle toxicity. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be administered if within 1-2 hours of ingestion. Monitor vital signs, blood gases, electrolytes, and renal function. Hemodialysis may be considered for severe salicylate toxicity. There is no specific antidote for rosuvastatin; manage symptoms and monitor liver and muscle enzymes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Take the capsule with food to reduce stomach upset. Avoid alcohol consumption as it can increase the risk of gastrointestinal bleeding and liver problems. Inform your doctor about all other medicines, supplements, and herbal products you are taking, especially blood thinners, other antiplatelet drugs, NSAIDs, and certain antibiotics. Regular blood tests to monitor liver function, kidney function, blood sugar, and lipid levels are important. If you are scheduled for any surgery or dental procedure, tell your healthcare provider that you are taking this medicine. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding without consulting your doctor. Keep this medicine out of reach of children and store it in its original container at room temperature.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, muscle toxicity, and renal impairment. The dose should be individualized, and renal and hepatic function should be monitored regularly. Falls and bleeding precautions should be taken.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy and in women planning to become pregnant. Rosuvastatin may cause fetal harm. Women of childbearing potential should use effective contraception while taking this medicine. If you become pregnant, stop the medicine immediately and consult your doctor.
🏥 Post-Surgery Considerations
This medicine may increase the risk of bleeding during and after surgery. It is often recommended to stop aspirin 5-7 days before surgery, but this decision should be made by your surgeon and cardiologist. Do not stop the medicine on your own. After surgery, your doctor will advise when to restart.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it increases the risk of bleeding during dental procedures. Your dentist may recommend stopping aspirin temporarily before certain procedures, but this should be discussed with your doctor. Good oral hygiene is important to prevent gum bleeding.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but avoid strenuous activities that may increase the risk of bleeding or injury, especially if you are prone to falls. If you experience muscle pain or weakness, stop exercising and consult your doctor. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine generally does not affect your ability to work or drive. However, if you experience dizziness, muscle pain, or unusual bleeding, avoid driving or operating heavy machinery and consult your doctor. Inform your employer about your medication if your job involves risk of injury or bleeding.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. It is usually continued long-term for cardiovascular protection. Your doctor may consider stopping it if you develop serious side effects such as severe bleeding, liver injury, or muscle toxicity. In some cases, it may be temporarily stopped before surgery or dental procedures.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. Regular monitoring of liver function, kidney function, lipid profile, and blood glucose is recommended. Prolonged use of aspirin may increase the risk of gastrointestinal bleeding and ulcers. Rosuvastatin may increase the risk of diabetes and muscle toxicity. Patients should have periodic eye exams due to potential risk of cataracts with statins. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight management can help control cholesterol and reduce cardiovascular risk.
Evidence: Well-establishedAtorvastatin or simvastatin may be used as alternatives to rosuvastatin.
Evidence: Well-establishedClopidogrel or prasugrel may be used instead of aspirin in some patients.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, patients on aspirin may have an increased risk of bleeding at injection sites. Inform your healthcare provider before receiving any vaccine. Annual influenza vaccination is recommended for patients with cardiovascular disease.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from light and moisture. If crossing time zones, continue taking your dose at the same time each day as close as possible. Check local customs regulations for carrying prescription medicines. Carry enough supply for your entire trip and a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antiplatelet effect of aspirin begins within 30-60 minutes, while the cholesterol-lowering effect of rosuvastatin starts within 1 week and reaches maximum effect in 2-4 weeks.
A: No, you should not stop taking this medicine without consulting your doctor. It is used for long-term prevention, and stopping suddenly may increase your risk of heart attack or stroke.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is contraindicated during pregnancy, especially in the second and third trimesters. Consult your doctor if you are pregnant or planning to become pregnant.
A: Inform your doctor about all other medications you are taking, as this medicine can interact with many drugs, including blood thinners, NSAIDs, and certain antibiotics.
🤔 Common Patient Concerns
🔄 Substitutes for rosze gold 10 capsule
View AllAlternative brands with exact same active ingredient:
-
davaindia rosuvastatin+aspirin 10mg/75mg capsuleDavaindia Generic Pharmacy ₹25.00 44.4% CHEAPER
-
danavish rosuvastatin+aspirin 10mg/75mg capsuleDanavish Healthcare ₹31.88 29.2% CHEAPER
-
rosprin 10mg/75mg capsuleFiner Pharmaceuticals Pvt Ltd ₹39.38 12.5% CHEAPER
-
davaindia aspirin+rosuvastatin+clopidogrel 75mg/10mg/75mg capsuleDavaindia Generic Pharmacy ₹41.80 7.1% CHEAPER
-
r10a 10 mg/75 mg capsuleCentaur Pharmaceuticals Pvt Ltd ₹42.03 6.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a doctor's prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: This medicine can be stopped once cholesterol levels are normal.
Fact: Cholesterol levels may rise again if the medicine is stopped. Consult your doctor before discontinuing. - Myth: This medicine can be taken with alcohol without any risk.
Fact: Alcohol increases the risk of gastrointestinal bleeding and liver problems. It should be avoided. - Myth: This medicine is safe for pregnant women.
Fact: This medicine is contraindicated in pregnancy due to risk of harm to the fetus.
🔄 Alternative Options
Generic Alternatives
- Aspirin 75 mg + Rosuvastatin 10 mg capsule (various manufacturers)
Brand Alternatives
- Azuvas 10-Gold Capsule