Arvast-A 75 Capsule: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit, or black tarry stools.
- Severe abdominal pain or persistent indigestion.
- Sudden severe headache, confusion, or difficulty speaking.
- Chest pain, shortness of breath, or rapid heartbeat.
- Severe muscle pain, weakness, or dark-colored urine.
- Yellowing of skin or eyes, or right upper abdominal pain.
- Decreased urine output or swelling in legs.
- Unusual bleeding from gums, nose, or easy bruising.
- Signs of allergic reaction such as rash, swelling of face or throat, or difficulty breathing.
If experiencing severe symptoms, call emergency services immediately.
What is davaindia rosuvastatin+aspirin 10mg/75mg capsule used for?
This medicine is a combination of Rosuvastatin 10 mg and Aspirin 75 mg used to lower cholesterol and prevent blood clots in patients at high risk of heart attack or stroke. It is taken once daily orally.
- Generic Name: Rosuvastatin + Aspirin
- Manufacturer: Davaindia Generic Pharmacy
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 davaindia rosuvastatin+aspirin 10mg/75mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा रोसुवास्टेटिन 10 मिलीग्राम और एस्पिरिन 75 मिलीग्राम का संयोजन है, जिसका उपयोग कोलेस्ट्रॉल कम करने और रक्त के थक्के बनने से रोकने के लिए किया जाता है। यह उन रोगियों के लिए निर्धारित की जाती है जिन्हें दिल का दौरा, स्ट्रोक या अन्य हृदय संबंधी समस्याओं का खतरा अधिक होता है। यह दवा खून में कोलेस्ट्रॉल के स्तर को कम करती है और प्लेटलेट्स को चिपकने से रोकती है, जिससे रक्त वाहिकाओं में थक्का बनने का खतरा कम होता है। यह दवा केवल डॉक्टर के पर्चे पर ही ली जानी चाहिए और नियमित रूप से कोलेस्ट्रॉल, लीवर और किडनी की जांच कराते रहना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में जलन, मतली, सिरदर्द, मांसपेशियों में दर्द और आसानी से चोट लगना शामिल हैं। एस्पिरिन के कारण पेट में अल्सर या रक्तस्राव हो सकता है। रोसुवास्टेटिन के कारण मांसपेशियों में दर्द, लीवर एंजाइम बढ़ना और दुर्लभ मामलों में गंभीर मांसपेशी क्षति हो सकती है। यदि आपको काला मल, उल्टी में खून, असामान्य चोट या मांसपेशियों में तेज दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे पानी के साथ निगलें, चबाएं नहीं। इसे हर दिन एक ही समय पर लें। शराब का सेवन न करें क्योंकि इससे रक्तस्राव और लीवर की समस्या बढ़ सकती है। बिना डॉक्टर की सलाह के कोई अन्य दर्द निवारक दवा न लें। यदि आपको पेट में अल्सर, रक्तस्राव विकार या लीवर की बीमारी है, तो डॉक्टर को बताएं। नियमित रूप से कोलेस्ट्रॉल, लीवर और किडनी की जांच कराएं। दवा अचानक बंद न करें।
💊 davaindia rosuvastatin+aspirin 10mg/75mg capsule Uses & Benefits
[{"condition":"Secondary prevention of cardiovascular events","description":"Reduces the risk of heart attack, stroke, and cardiovascular death in patients with established atherosclerotic cardiovascular disease.","evidence":"Well-established"},{"condition":"Primary prevention in high-risk individuals","description":"May be used in patients with multiple risk factors such as diabetes, hypertension, and dyslipidemia to prevent first cardiovascular events.","evidence":"Established"},{"condition":"Dyslipidemia","description":"Lowers elevated LDL cholesterol, total cholesterol, and triglycerides, and increases HDL cholesterol in patients with hypercholesterolemia.","evidence":"Well-established"},{"condition":"Acute coronary syndrome","description":"Used as part of long-term management after acute coronary syndrome to prevent recurrent thrombotic events.","evidence":"Well-established"},{"condition":"Ischemic stroke or transient ischemic attack","description":"Aspirin component helps prevent recurrent strokes; statin component manages underlying atherosclerosis.","evidence":"Well-established"},{"condition":"Peripheral arterial disease","description":"Reduces risk of cardiovascular events and improves outcomes in patients with peripheral arterial disease.","evidence":"Established"}]
Off-label uses: [{"condition":"Prevention of preeclampsia","description":"Low-dose aspirin is sometimes used off-label for prevention of preeclampsia in high-risk pregnancies, but this combination is not indicated for this purpose.","evidence":"Limited"},{"condition":"Antiphospholipid syndrome","description":"Aspirin may be used off-label in some patients with antiphospholipid syndrome, but statin component is not standard.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease prevention (secondary prevention of myocardial infarction, stroke, and cardiovascular death)
Also treats: Dyslipidemia, Coronary artery disease, Ischemic stroke, Peripheral arterial disease, Diabetes mellitus with cardiovascular risk factors
📋 Drug Information
| Generic Name(s) | Rosuvastatin + Aspirin |
| Brand Name | Arvast-A 75 Capsule |
| Manufacturer | Davaindia Generic Pharmacy |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Antiplatelet Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Rosuvastatin selectively and competitively inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate, a rate-limiting step in cholesterol biosynthesis. This inhibition leads to upregulation of hepatic LDL receptors, increased clearance of LDL cholesterol from the blood, and reduced hepatic cholesterol synthesis. Aspirin irreversibly acetylates cyclooxygenase-1 (COX-1) in platelets, preventing the conversion of arachidonic acid to prostaglandin H2 and subsequently thromboxane A2. Thromboxane A2 is a potent vasoconstrictor and platelet aggregator; its reduction leads to decreased platelet aggregation and prolonged bleeding time. The combination provides both lipid-lowering and antiplatelet effects, addressing two major pathways in atherothrombosis.
Mechanism Steps
💡 How to Take davaindia rosuvastatin+aspirin 10mg/75mg capsule
Strength: Capsule containing Rosuvastatin 10 mg and Aspirin 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule (Rosuvastatin 10 mg + Aspirin 75 mg) taken orally once daily, with or without food. The dose may be adjusted by the physician based on the patient's lipid levels, cardiovascular risk, and tolerability. For patients with severe renal impairment (creatinine clearance <30 mL/min), a lower starting dose of rosuvastatin (5 mg) is recommended, but this fixed-dose combination may not be suitable. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more susceptible to the side effects of this medicine, particularly gastrointestinal bleeding, muscle toxicity, and renal impairment. The dose should be individualized by a clinician. Regular monitoring of renal function, liver enzymes, and bleeding signs is advised. The lowest effective dose should be used. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually required. In severe renal impairment (creatinine clearance <30 mL/min), rosuvastatin should be started at a lower dose (5 mg) and titrated carefully. Aspirin should be used with caution due to increased risk of bleeding and renal toxicity. This fixed-dose combination may not be appropriate; consult a nephrologist. |
| Hepatic Impairment | This medicine is contraindicated in patients with active liver disease or unexplained persistent elevations of serum transaminases. In patients with mild to moderate hepatic impairment, rosuvastatin should be used with caution and at lower doses. Aspirin should be avoided in severe hepatic impairment due to risk of bleeding and encephalopathy. Consult a hepatologist for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose of this fixed-dose combination is one capsule (Rosuvastatin 10 mg + Aspirin 75 mg) once daily. Higher doses of rosuvastatin (up to 40 mg) may be prescribed separately, but this combination is not designed for dose escalation. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of davaindia rosuvastatin+aspirin 10mg/75mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| NSAIDs | Major | |
| Cyclosporine | Major | |
| Gemfibrozil | Major | |
| Clopidogrel | Moderate | |
| Methotrexate | Moderate | |
| ACE inhibitors | Moderate | |
| Furosemide | Moderate | |
| Antacids | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Warfarin
- Other anticoagulants (e.g., heparin, dabigatran, rivaroxaban)
- NSAIDs (e.g., ibuprofen, naproxen)
- Cyclosporine
- Gemfibrozil
⚡ Moderate Interactions
- Clopidogrel
- Methotrexate
- ACE inhibitors
- Furosemide
- Antacids
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding due to aspirin's antiplatelet effect and can exacerbate liver toxicity from rosuvastatin. It may also increase the risk of muscle-related side effects. If you consume alcohol, limit intake and discuss with your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to rosuvastatin, aspirin, or any component of the formulation.","Active peptic ulcer disease or history of recurrent ulcers.","Active bleeding or bleeding disorders (e.g., hemophilia, thrombocytopenia).","Severe liver disease or unexplained persistent elevations of serum transaminases.","Pregnancy and breastfeeding.","Aspirin-sensitive asthma or NSAID-induced anaphylaxis.","Concurrent use with cyclosporine or gemfibrozil.","Children under 18 years of age (unless specifically prescribed by a specialist)."]
⚠️ Warnings & Precautions
["This medicine should be used with caution in patients with a history of gastrointestinal ulcers or bleeding.","Patients with renal impairment should be monitored closely; dose adjustment may be necessary.","Avoid in patients with active liver disease or unexplained transaminase elevations.","Use with caution in elderly patients due to increased risk of bleeding and muscle toxicity.","Inform your doctor if you have diabetes, hypothyroidism, or a history of muscle disorders.","Do not use during pregnancy or breastfeeding.","Avoid alcohol consumption while taking this medicine.","Do not take other NSAIDs or blood thinners without consulting your doctor.","Report any unusual bleeding, bruising, muscle pain, or dark urine immediately.","Regular monitoring of lipid profile, liver enzymes, and renal function is recommended."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding. Both rosuvastatin and aspirin are excreted in breast milk. Rosuvastatin may interfere with infant lipid metabolism, and aspirin may cause bleeding risks in the infant. Consult your doctor for alternative treatments if breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause salicylate toxicity (tinnitus, hyperventilation, metabolic acidosis, hypoglycemia) and statin-related effects (muscle toxicity, liver injury). If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be administered if ingestion is recent. Hemodialysis may be considered for severe salicylate toxicity. Monitor vital signs, blood gases, electrolytes, and renal function. There is no specific antidote for rosuvastatin; manage symptoms and monitor liver and muscle enzymes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily. Swallow the capsule whole with a glass of water; do not crush or chew. Take it at the same time each day to maintain consistent blood levels. Avoid alcohol consumption as it increases the risk of liver problems and gastrointestinal bleeding. Do not take other pain relievers or blood thinners without consulting your doctor. Inform your doctor if you have a history of ulcers, bleeding disorders, or liver disease. Regular blood tests for cholesterol, liver function, and bleeding parameters may be required. Do not stop this medicine abruptly without medical advice. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose; never double the dose. Store at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, renal impairment, and muscle toxicity. The dose should be individualized, and regular monitoring of renal function, liver enzymes, and bleeding signs is advised. The lowest effective dose should be used.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy and should be stopped before attempting to conceive. Women of childbearing potential should use effective contraception while taking this medicine. If you are planning pregnancy, consult your doctor to switch to alternative treatments.
🏥 Post-Surgery Considerations
This medicine should be stopped before any surgery or dental procedure due to the risk of bleeding. Consult your surgeon or dentist for specific instructions. It is usually recommended to stop aspirin 5-7 days before surgery, but this decision must be made by your healthcare provider.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure, as it increases the risk of bleeding. Your dentist may recommend stopping the medicine temporarily or taking precautions to control bleeding. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but avoid contact sports or activities that carry a high risk of injury or bleeding due to the antiplatelet effect of aspirin. If you experience muscle pain or weakness, stop exercising and consult your doctor, as it may be a sign of statin-induced myopathy.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine generally does not affect your ability to work or drive. However, if you experience dizziness, muscle pain, or unusual bleeding, avoid driving or operating heavy machinery until you feel better. Inform your employer if your job involves a high risk of injury, as the antiplatelet effect may increase bleeding risk.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. It is usually continued long-term for cardiovascular protection. If you experience serious side effects such as severe bleeding, muscle pain, or liver problems, contact your doctor immediately; they may adjust or stop the medicine. Abrupt discontinuation may increase the risk of cardiovascular events.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and beneficial for cardiovascular protection. However, it requires regular monitoring of lipid profile, liver enzymes, and renal function. Prolonged aspirin use can increase the risk of gastrointestinal bleeding and ulcers. Rosuvastatin may rarely cause muscle toxicity or liver enzyme elevation. Patients should remain vigilant for signs of bleeding, muscle pain, or liver problems. Periodic review with your doctor is essential to adjust therapy as needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and smoking cessation can complement medicine and improve cardiovascular health.
Evidence: Well-establishedAtorvastatin or simvastatin may be used if rosuvastatin is not tolerated.
Evidence: Well-establishedClopidogrel may be used if aspirin is not tolerated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, patients on aspirin may have an increased risk of bleeding at injection sites. Inform your healthcare provider before receiving any vaccine. Annual influenza vaccination is recommended for patients with cardiovascular disease.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, continue taking your dose at the same local time as usual; if this is not possible, consult your doctor for adjustment. Carry enough supply for the entire trip plus extra in case of delays. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antiplatelet effect of aspirin starts within 30-60 minutes, while the cholesterol-lowering effect of rosuvastatin begins within 1 week and reaches maximum effect in 2-4 weeks.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is best to avoid alcohol as it increases the risk of gastrointestinal bleeding and liver toxicity.
A: No, this medicine is contraindicated during pregnancy as it may harm the fetus. Consult your doctor for alternative treatments.
A: Do not stop without consulting your doctor. This medicine is usually continued long-term to maintain cardiovascular protection.
🤔 Common Patient Concerns
🔄 Substitutes for davaindia rosuvastatin+aspirin 10mg/75mg capsule
View AllAlternative brands with exact same active ingredient:
-
danavish rosuvastatin+aspirin 10mg/75mg capsuleDanavish Healthcare ₹31.88 27.5% COSTLIER
-
rosprin 10mg/75mg capsuleFiner Pharmaceuticals Pvt Ltd ₹39.38 57.5% COSTLIER
-
davaindia aspirin+rosuvastatin+clopidogrel 75mg/10mg/75mg capsuleDavaindia Generic Pharmacy ₹41.80 67.2% COSTLIER
-
r10a 10 mg/75 mg capsuleCentaur Pharmaceuticals Pvt Ltd ₹42.03 68.1% COSTLIER
-
rosze gold 10 capsuleZeelab Pharmacy Pvt Ltd ₹45.00 80% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription-only drug and must be taken under medical supervision. - Myth: This medicine can be stopped once cholesterol levels are normal.
Fact: This medicine is usually continued long-term to maintain cardiovascular protection. Do not stop without consulting your doctor. - Myth: This medicine can be taken with any painkiller.
Fact: Taking NSAIDs with this medicine increases the risk of gastrointestinal bleeding. Consult your doctor before taking any painkiller. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is contraindicated during pregnancy as it may harm the fetus.
🔄 Alternative Options
Generic Alternatives
- Rosuvastatin 10 mg + Aspirin 75 mg capsule (generic)
Brand Alternatives
- Arvast-A 75 capsule
- Rosuvas-A 75 capsule
- Rosuvastatin + Aspirin combinations