Fasrose ASF Capsule: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unexplained muscle pain or weakness
If experiencing severe symptoms, call emergency services immediately.
What is rosumac asp 20mg/75mg capsule used for?
This medicine is a combination of Rosuvastatin 20 mg and Aspirin 75 mg used to lower cholesterol and prevent blood clots in patients at high risk of cardiovascular events. It is taken orally once daily with food.
- Generic Name: Rosuvastatin (20mg) + Aspirin (75mg)
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 rosumac asp 20mg/75mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा रोसुवास्टेटिन 20 मिलीग्राम और एस्पिरिन 75 मिलीग्राम का संयोजन है। इसका उपयोग कोलेस्ट्रॉल कम करने और रक्त के थक्के बनने से रोकने के लिए किया जाता है, खासकर उन रोगियों में जिनमें हृदय रोग का खतरा अधिक होता है। यह दवा हृदयाघात और स्ट्रोक के जोखिम को कम करने में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में अपच, मतली, पेट दर्द, सिरदर्द, मांसपेशियों में दर्द और आसानी से चोट लगना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, अल्सर, मांसपेशियों की गंभीर समस्या और लीवर की क्षति शामिल हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे रक्तस्राव का खतरा बढ़ सकता है। अन्य दवाओं के साथ लेने से पहले डॉक्टर से सलाह लें। नियमित रूप से लीवर और किडनी की जांच करवाएं।
💊 rosumac asp 20mg/75mg capsule Uses & Benefits
[{"condition":"Secondary prevention of cardiovascular events","description":"Reduces the risk of heart attack, stroke, and cardiovascular death in patients with established atherosclerotic cardiovascular disease.","evidence":"Well-established"},{"condition":"Hypercholesterolemia","description":"Lowers elevated LDL cholesterol and total cholesterol in patients with primary hypercholesterolemia or mixed dyslipidemia.","evidence":"Well-established"},{"condition":"Acute coronary syndrome","description":"Used as part of long-term management after acute coronary syndrome to prevent recurrent events.","evidence":"Well-established"},{"condition":"Peripheral arterial disease","description":"Helps reduce the risk of cardiovascular events in patients with peripheral arterial disease.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Primary prevention in high-risk individuals","description":"Sometimes prescribed off-label for primary prevention in patients with multiple risk factors but no established cardiovascular disease.","evidence":"Limited"},{"condition":"Diabetic dyslipidemia","description":"May be used off-label for cardiovascular risk reduction in diabetic patients with dyslipidemia.","evidence":"Moderate"}]
Primary treatment for: Cardiovascular disease prevention
Also treats: Hypercholesterolemia, Atherosclerosis, Acute coronary syndrome, Peripheral arterial disease
📋 Drug Information
| Generic Name(s) | Rosuvastatin (20mg) + Aspirin (75mg) |
| Brand Name | rosumac asp 20mg/75mg capsule |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Rosuvastatin selectively and competitively inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate, a rate-limiting step in cholesterol biosynthesis. This inhibition leads to upregulation of hepatic LDL receptors, increased clearance of LDL cholesterol from the bloodstream, and reduced hepatic cholesterol synthesis. Aspirin acetylates serine residues on cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, irreversibly inhibiting them. This prevents the conversion of arachidonic acid to prostaglandin H2, thereby reducing thromboxane A2 production in platelets. Thromboxane A2 is a potent vasoconstrictor and platelet aggregator; its reduction leads to decreased platelet aggregation and prolonged bleeding time.
Mechanism Steps
💡 How to Take rosumac asp 20mg/75mg capsule
Strength: Capsule containing Rosuvastatin 20 mg and Aspirin 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule (Rosuvastatin 20 mg + Aspirin 75 mg) taken orally once daily, preferably with food. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and cardiovascular risk. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects, especially gastrointestinal bleeding and muscle toxicity. Dose should be individualized by a clinician. Regular monitoring is recommended. |
| Renal Impairment | In patients with renal impairment, rosuvastatin dose should be adjusted. Aspirin should be used with caution. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Contraindicated in severe hepatic impairment. In mild to moderate hepatic impairment, dose adjustment may be necessary. Consult a clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Rosuvastatin 20 mg + Aspirin 75 mg). Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of rosumac asp 20mg/75mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| NSAIDs | Major | |
| Cyclosporine | Major | |
| Gemfibrozil | Major | |
| Clopidogrel | Moderate | |
| Methotrexate | Moderate | |
| ACE inhibitors | Moderate | |
| Antacids | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- Warfarin
- NSAIDs
- Cyclosporine
- Gemfibrozil
⚡ Moderate Interactions
- Clopidogrel
- Methotrexate
- ACE inhibitors
🍷 Alcohol Interaction
Alcohol increases the risk of gastrointestinal bleeding and hepatotoxicity when taken with this medicine. It is advisable to avoid alcohol completely while on this medication.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active bleeding or bleeding disorders","Aspirin-sensitive asthma","Severe liver disease","Pregnancy and breastfeeding","Hypersensitivity to rosuvastatin or aspirin","Active peptic ulcer disease"]
⚠️ Warnings & Precautions
["Use with caution in patients with history of gastrointestinal ulcers or bleeding.","Avoid in patients with severe renal impairment.","Monitor liver function regularly.","Discontinue if signs of myopathy or rhabdomyolysis occur.","Avoid alcohol consumption.","Use with caution in elderly patients.","Do not use in children without specialist advice."]
🤱 Lactation Safety
Not recommended during breastfeeding. Rosuvastatin and aspirin may pass into breast milk and could harm the infant. Consult your doctor for alternative options.
💊 Overdose Management
Overdose may cause severe gastrointestinal bleeding, liver toxicity, or rhabdomyolysis. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote for rosuvastatin; aspirin overdose may be treated with activated charcoal, gastric lavage, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush or chew the capsule; swallow it whole with water. Take it at the same time each day, preferably with food to reduce stomach irritation. Avoid alcohol consumption as it increases the risk of gastrointestinal bleeding and liver problems. Inform your doctor if you have a history of ulcers, bleeding disorders, or liver or kidney disease. Do not start or stop any other medication without consulting your doctor, especially blood thinners, NSAIDs, or other cholesterol-lowering drugs. Regular monitoring of liver function, kidney function, and lipid profile is essential. Report any unusual bleeding, muscle pain, or dark urine immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, muscle toxicity, and renal impairment. Dose should be individualized, and regular monitoring is recommended.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy and in women planning pregnancy. Consult your doctor for alternative treatments before conception.
🏥 Post-Surgery Considerations
This medicine may increase bleeding risk during and after surgery. Inform your surgeon and stop the medicine as advised before any surgical procedure.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may recommend stopping aspirin temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but avoid strenuous activities that may cause injury or bleeding. If you experience muscle pain or weakness, stop exercise and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some individuals. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it generally does not interfere with daily activities.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects like severe bleeding, muscle pain, or liver problems, seek immediate medical advice. Your doctor may adjust or discontinue the medicine based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of liver function, kidney function, and lipid profile. It may increase the risk of gastrointestinal bleeding and muscle toxicity. Periodic eye exams are recommended for patients on aspirin. Do not stop the medicine without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and smoking cessation can complement medicine for cardiovascular risk reduction.
Evidence: Well-establishedAtorvastatin or simvastatin may be alternatives if rosuvastatin is not tolerated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your doctor before any vaccination, especially if you are on other medications.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. When traveling across time zones, continue taking your dose at the same local time as much as possible. If you miss a dose due to time change, take it as soon as you remember unless it is almost time for the next dose. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Rosuvastatin starts lowering cholesterol within 1 week, with maximum effect in 2-4 weeks. Aspirin's antiplatelet effect begins within 30-60 minutes.
A: Inform your doctor about all medications you take, as this medicine can interact with many drugs, especially blood thinners and NSAIDs.
A: If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for rosumac asp 20mg/75mg capsule
View AllAlternative brands with exact same active ingredient:
-
davaindia rosuvastatin+aspirin 20mg/75mg capsuleDavaindia Generic Pharmacy ₹35.00 53.6% CHEAPER
-
rosuvotin asp 20mg/75mg tabletLividus Pharmaceuticals Pvt Ltd ₹61.88 17.9% CHEAPER
-
unizuva a 20mg/75mg capsuleUniza Healthcare LLP ₹70.00 7.2% CHEAPER
-
rosze gold 20 capsuleZeelab Pharmacy Pvt Ltd ₹70.00 7.2% CHEAPER
-
stayhappi aspirin/acetylsalicylic acid+rosuvastatin+clopidogrel 75mg/20mg/75mg capsuleSarvagunaushdhi Pvt Ltd ₹80.63 6.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: I can stop taking this medicine once my cholesterol is normal.
Fact: Cholesterol levels may rise again if the medicine is stopped. Consult your doctor before stopping. - Myth: This medicine can be taken with any other medication.
Fact: This medicine can interact with many drugs. Always inform your doctor about all medications you take.
🔄 Alternative Options
Generic Alternatives
- Rosuvastatin 20 mg + Aspirin 75 mg capsule
Brand Alternatives
- Fasrose ASF Capsule