Alviroz F 145mg/10mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe muscle pain, tenderness, or weakness, especially with dark urine or fever.
- Yellowing of skin or eyes, dark urine, or severe abdominal pain.
- Signs of allergic reaction such as rash, itching, swelling of face, lips, or throat, or difficulty breathing.
- Severe abdominal pain radiating to the back, with nausea and vomiting.
- Unusual bleeding or bruising.
- Decreased urine output or swelling in legs.
If experiencing severe symptoms, call emergency services immediately.
What is rosukaa f tablet used for?
This medicine is a combination of fenofibrate and rosuvastatin used to treat mixed dyslipidemia by lowering triglycerides and LDL cholesterol while raising HDL cholesterol. It is taken once daily with food under medical supervision.
- Generic Name: Fenofibrate (145mg) + Rosuvastatin (10mg)
- Manufacturer: Troikaa Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 rosukaa f tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फेनोफिब्रेट और रोसुवास्टेटिन का संयोजन है, जिसका उपयोग मिश्रित डिस्लिपिडेमिया के इलाज के लिए किया जाता है। यह ट्राइग्लिसराइड और एलडीएल कोलेस्ट्रॉल को कम करने और एचडीएल कोलेस्ट्रॉल को बढ़ाने में मदद करती है। इसे भोजन के साथ दिन में एक बार लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, पेट दर्द, कब्ज और मांसपेशियों में दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें रैब्डोमायोलिसिस और लीवर की समस्या शामिल हो सकती है। मांसपेशियों में असामान्य दर्द या कमजोरी होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि अवशोषण बेहतर हो और पेट की परेशानी कम हो। शराब का सेवन न करें क्योंकि इससे लीवर की समस्या बढ़ सकती है। अन्य दवाओं के बारे में डॉक्टर को बताएं। नियमित रूप से लीवर, किडनी और लिपिड प्रोफाइल की जांच कराएं। गर्भावस्था या स्तनपान के दौरान इस दवा का सेवन न करें।
💊 rosukaa f tablet Uses & Benefits
[{"condition":"Mixed dyslipidemia","description":"This medicine is used to reduce elevated LDL cholesterol, total cholesterol, and triglycerides while increasing HDL cholesterol in patients with combined lipid abnormalities.","evidence":"Well-established"},{"condition":"Hypertriglyceridemia with high LDL","description":"It is prescribed when both triglycerides and LDL cholesterol are significantly elevated and lifestyle changes alone are insufficient.","evidence":"Well-established"},{"condition":"Primary hypercholesterolemia","description":"Used as an adjunct to diet when statin monotherapy does not achieve target LDL levels and triglycerides remain high.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Non-alcoholic fatty liver disease","description":"Sometimes prescribed off-label to improve liver enzymes and lipid profile in patients with fatty liver, but evidence is limited.","evidence":"Limited"},{"condition":"Diabetic dyslipidemia","description":"May be used off-label in patients with type 2 diabetes and mixed lipid disorders, though not specifically approved for this indication.","evidence":"Limited"}]
Primary treatment for: Mixed dyslipidemia
Also treats: Hypertriglyceridemia, Hypercholesterolemia, Diabetic dyslipidemia, Metabolic syndrome
📋 Drug Information
| Generic Name(s) | Fenofibrate (145mg) + Rosuvastatin (10mg) |
| Brand Name | rosukaa f tablet |
| Manufacturer | Troikaa Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary lipid-lowering actions. Fenofibrate activates peroxisome proliferator-activated receptor alpha (PPAR-alpha), which increases the expression of genes involved in fatty acid oxidation and lipoprotein lipase activity. This leads to increased breakdown of triglyceride-rich particles and increased production of apolipoprotein A-I and HDL cholesterol. Rosuvastatin selectively inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate, a rate-limiting step in cholesterol biosynthesis. This inhibition upregulates LDL receptors in the liver, enhancing clearance of LDL cholesterol from the blood. Together, these mechanisms provide broad-spectrum lipid control.
Mechanism Steps
💡 How to Take rosukaa f tablet
Strength: Tablet containing fenofibrate 145 mg and rosuvastatin 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet of fenofibrate 145 mg and rosuvastatin 10 mg taken orally once daily with food. The dose may be adjusted by the doctor based on lipid levels and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Dose should be individualized based on renal and hepatic function. Regular monitoring is recommended. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually needed. However, in severe renal impairment (eGFR <30 mL/min/1.73 m2), this medicine is contraindicated. Consult a doctor for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with active liver disease or unexplained persistent transaminase elevations. In patients with mild hepatic impairment, use with caution and monitor liver function closely. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet containing fenofibrate 145 mg and rosuvastatin 10 mg. Do not exceed this dose unless directed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of rosukaa f tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Cyclosporine | Major | |
| Gemfibrozil | Major | |
| Protease inhibitors | Major | |
| Antacids | Moderate | |
| Colchicine | Moderate | |
| Fusidic acid | Moderate | |
| Oral contraceptives | Minor | |
| Thiazide diuretics | Minor | |
| Digoxin | Minor |
🚨 Major Interactions
- Warfarin
- Cyclosporine
- Gemfibrozil
- Protease inhibitors
⚡ Moderate Interactions
- Antacids containing aluminum or magnesium
- Colchicine
- Fusidic acid
🍷 Alcohol Interaction
Drinking alcohol while taking this medicine can increase the risk of liver problems and may reduce the effectiveness of lipid-lowering therapy. It is advisable to limit alcohol intake or avoid it completely, especially if you have a history of liver disease or high triglycerides.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active liver disease or unexplained persistent elevations of serum transaminases.","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Muscle effects: Report unexplained muscle pain, tenderness, or weakness, especially if accompanied by malaise or fever. Discontinue if myopathy is suspected.","Liver effects: Monitor liver enzymes. Discontinue if signs of liver injury occur.","Kidney effects: Use with caution in patients with renal impairment. Dose adjustment may be needed.","Diabetes: May increase blood glucose levels. Monitor glycemic control.","Thyroid disease: May affect thyroid function tests. Monitor if symptoms occur.","Alcohol use: Avoid excessive alcohol consumption due to increased risk of liver damage.","Pregnancy: Contraindicated. Use effective contraception.","Breastfeeding: Do not breastfeed while taking this medicine.","Pediatric use: Safety and efficacy not established.","Elderly: Use with caution, monitor renal and liver function."]
🤱 Lactation Safety
It is not known whether fenofibrate or rosuvastatin are excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, this medicine should not be used during breastfeeding. Alternative treatments should be considered.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of suspected overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor liver and kidney function, and creatine kinase levels. Hemodialysis is not expected to significantly enhance elimination of rosuvastatin or fenofibrate.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Take the tablet with food to improve absorption and reduce stomach upset. Avoid drinking large amounts of alcohol while on this medicine because it can increase the risk of liver problems. Inform your doctor about all other medicines you are taking, especially blood thinners, other cholesterol medicines, and certain antibiotics. Report any unexplained muscle pain, weakness, or dark urine immediately. Keep all scheduled appointments for blood tests to check liver function, kidney function, and lipid levels. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Store the tablets at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to muscle and liver side effects. Dose should be individualized based on renal and hepatic function. Regular monitoring of kidney and liver function is recommended.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. Women planning pregnancy should stop this medicine and consult their doctor for alternative treatments. Effective contraception should be used while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to potential interactions with other medications and effects on liver and kidney function. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. No specific precautions are usually needed for routine dental procedures, but if you are taking blood thinners, additional bleeding precautions may be necessary.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is encouraged, but if you experience muscle pain, weakness, or cramps during exercise, stop and consult your doctor. Intense or unaccustomed exercise may increase the risk of muscle injury while on this medicine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness, muscle pain, or fatigue, avoid driving or operating heavy machinery until you feel well. Most patients can continue their normal daily activities.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as severe muscle pain, liver problems, or allergic reactions, seek immediate medical advice. Your doctor may adjust the dose or switch to an alternative treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. Regular monitoring of liver enzymes, kidney function, and lipid profile is essential. Rarely, long-term use may be associated with muscle toxicity, liver injury, or gallbladder disease. Patients should continue lifestyle modifications and attend regular follow-ups.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight management can complement medicine for lipid control.
Evidence: Well-establishedMay help lower triglycerides but less effective than prescription medicines.
Evidence: ModerateCan improve lipid profile but often limited by side effects.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, continue taking your dose at the usual local time; no major adjustments are needed for once-daily dosing. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Lipid-lowering effects begin within 1 to 2 weeks, but maximum effect is usually seen after 4 to 6 weeks of consistent use.
A: It is best taken with food to improve absorption of fenofibrate and reduce stomach upset.
A: Take it as soon as you remember if less than 12 hours have passed. If more than 12 hours, skip it and continue with your regular schedule. Do not double dose.
A: Avoid large amounts of grapefruit juice and limit alcohol intake. Maintain a heart-healthy diet.
🤔 Common Patient Concerns
🔄 Substitutes for rosukaa f tablet
View AllAlternative brands with exact same active ingredient:
-
rosu f 145mg/10mg tabletDavaindia Generic Pharmacy ₹31.00 86.9% CHEAPER
-
lipira f 145 mg/10 mg tabletEmcure Pharmaceuticals Ltd ₹87.09 63.3% CHEAPER
-
Rolmo F 145mg/10mg TabletAblus Pharma ₹93.75 60.4% CHEAPER
-
Roslong F 145mg/10mg TabletSunmarker Pharma ₹98.44 58.5% CHEAPER
-
brosuv f 145 tabletBrilliant Lifesciences Pvt Ltd ₹101.25 57.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without food.
Fact: Fenofibrate absorption is significantly improved when taken with food, so it should be taken with a meal. - Myth: Once cholesterol levels are normal, the medicine can be stopped.
Fact: Cholesterol levels may rise again if the medicine is stopped. Continue as prescribed and consult your doctor before making any changes. - Myth: This medicine can replace a healthy diet and exercise.
Fact: This medicine is an adjunct to diet and exercise. Lifestyle modifications are essential for optimal cardiovascular risk reduction.
🔄 Alternative Options
Generic Alternatives
- Fenofibrate and rosuvastatin combination generic tablets