riaser d 10mg/50mg tablet - Diclofenac (10mg) + Serratiopeptidase (50mg) medicine

Riaser D 10mg/50mg Tablet: Complete Medicine Guide

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🏭 Riasmo Lifesciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Diclofenac is generally avoided in the third trimester due to risk of premature closure of ductus arteriosus. Serratiopeptidase safety in pregnancy is not established. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for combination; individual components have well-established evidence.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is riaser d 10mg/50mg tablet used for?

This medicine is a combination of Diclofenac 10 mg and Serratiopeptidase 50 mg used to relieve pain, swelling, and inflammation in conditions like arthritis and soft tissue injuries. It works by reducing prostaglandins and breaking down fibrin. Take it with food, avoid alcohol, and do not exceed the prescribed dose.

  • Generic Name: Diclofenac (10mg) + Serratiopeptidase (50mg)
  • Manufacturer: Riasmo Lifesciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 riaser d 10mg/50mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डाइक्लोफेनाक 10 मिलीग्राम और सेरेशियोपेप्टिडेज 50 मिलीग्राम का संयोजन है। इसका उपयोग गठिया, जोड़ों के दर्द, सूजन, और चोट से होने वाली सूजन को कम करने के लिए किया जाता है। यह दर्द और सूजन को कम करने में मदद करती है। इसे भोजन के साथ लें और शराब से बचें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और दाने शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत विषाक्तता, और हृदय संबंधी घटनाएं शामिल हो सकती हैं। यदि आपको काला मल, उल्टी में रक्त, तेज पेट दर्द, सीने में दर्द, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। शराब और धूम्रपान से बचें। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आपको पेट अल्सर, गुर्दे या यकृत की बीमारी, हृदय रोग, अस्थमा, या रक्तस्राव विकार है तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 riaser d 10mg/50mg tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Soft tissue injuries","description":"Reduces swelling and pain in sprains, strains, and sports injuries.","evidence":"Moderate"},{"condition":"Post-operative inflammation","description":"Used to decrease swelling and pain after surgical procedures.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label for preventing migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but not a first-line treatment.","evidence":"Limited"}]

Primary treatment for: Inflammatory pain conditions

Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Soft tissue injuries, Post-operative inflammation

📋 Drug Information

Generic Name(s)Diclofenac (10mg) + Serratiopeptidase (50mg)
Brand Nameriaser d 10mg/50mg tablet
ManufacturerRiasmo Lifesciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Do not drive or operate machinery if you feel dizzy.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Swelling after injury
This medicine helps reduce swelling.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDiclofenac is rapidly absorbed from the gastrointestinal tract after oral administration. Serratiopeptidase is absorbed intact through the intestinal mucosa, though its bioavailability is limited. Food may delay absorption of diclofenac but does not significantly reduce the extent of absorption.
DistributionDiclofenac is highly bound to plasma proteins and distributes widely into tissues, including synovial fluid. Serratiopeptidase distributes to inflamed tissues and lymphatics.
Protein BindingDiclofenac is approximately 99% bound to plasma proteins, primarily albumin. Serratiopeptidase binding is not well established.
MetabolismDiclofenac is extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C9, to several metabolites. Serratiopeptidase is metabolized by proteolysis into amino acids.
Half-LifeThe elimination half-life of diclofenac is approximately 1-2 hours. The half-life of serratiopeptidase is not well established.
ExcretionDiclofenac metabolites are excreted mainly in urine (about 65%) and bile/feces (about 35%). Serratiopeptidase is excreted as amino acids via normal protein metabolism.
BioavailabilityThe oral bioavailability of diclofenac is approximately 50-60% due to first-pass metabolism. The bioavailability of serratiopeptidase is not well established.
Onset of ActionDiclofenac begins to relieve pain within 30-60 minutes after oral administration. Serratiopeptidase effects on swelling may take several hours to days.
Peak Plasma TimePeak plasma concentration of diclofenac is reached in about 1-2 hours after oral administration. Peak levels of serratiopeptidase are not well established.
Duration of ActionThe analgesic and anti-inflammatory effects of diclofenac last about 4-6 hours. Serratiopeptidase effects may persist longer due to its mechanism.

How It Works

This medicine combines two active ingredients. Diclofenac is a nonsteroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased synthesis of prostaglandins, prostacyclin, and thromboxane. This results in analgesic, antipyretic, and anti-inflammatory effects. Serratiopeptidase is a proteolytic enzyme that hydrolyzes fibrin, bradykinin, and other inflammatory mediators, thereby reducing edema and promoting tissue repair. Together, they provide symptomatic relief in inflammatory conditions.

Mechanism Steps

1
COX enzyme inhibition: Diclofenac binds to and inhibits cyclooxygenase enzymes, blocking the conversion of arachidonic acid to prostaglandins.
2
Reduced prostaglandin synthesis: Decreased prostaglandin levels lead to reduced pain, fever, and inflammation.
3
Proteolytic enzyme action: Serratiopeptidase hydrolyzes fibrin and other proteins, reducing edema and promoting clearance of inflammatory debris.
4
Enhanced tissue penetration: Serratiopeptidase may improve penetration of diclofenac into inflamed tissues, enhancing its effects.

💡 How to Take riaser d 10mg/50mg tablet

Strength: Tablet containing Diclofenac 10 mg and Serratiopeptidase 50 mg.

1Take the tablet with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole. Do not crush or chew.
4Take at the same time each day to maintain consistent levels.
5Do not lie down immediately after taking the tablet.
6Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally one to two times daily, preferably with food. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Do not exceed the recommended dose. For short-term use only.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function closely.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose adjustment may be required. Consult your doctor. Avoid in severe kidney impairment.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose adjustment may be required. Consult your doctor. Avoid in severe liver impairment.
Maximum Daily DoseThe maximum recommended daily dose is 2 tablets (20 mg diclofenac and 100 mg serratiopeptidase). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of riaser d 10mg/50mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. If severe, contact your doctor.
Indigestion (Common (5-10%))
Take with meals. Antacids may help, but consult your doctor first.
Headache (Common (5-10%))
Usually resolves on its own. If persistent, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Liver toxicity (Rare (<0.1%))
Seek medical help if you develop yellowing of skin or eyes, dark urine, or severe fatigue.
Cardiovascular events (Rare (<0.1%))
Call emergency services if you experience chest pain, shortness of breath, or sudden weakness.
Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you have swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention if you experience severe headache, stiff neck, and fever.
Pancreatitis
Report severe abdominal pain radiating to the back to your doctor immediately.
Blood disorders
Consult your doctor if you notice unusual bleeding, bruising, or signs of infection.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
ACE inhibitors Major
Diuretics Major
Lithium Major
Corticosteroids Moderate
Methotrexate Moderate
SSRIs Moderate
Antacids Minor
Aspirin Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • ACE inhibitors
  • Diuretics
  • Lithium

⚡ Moderate Interactions

  • Corticosteroids
  • Methotrexate
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver toxicity. It may also worsen dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active peptic ulcer or gastrointestinal bleeding","Severe kidney impairment","Severe liver impairment","History of asthma, urticaria, or allergic reaction to NSAIDs","Third trimester of pregnancy","Coronary artery bypass graft surgery","Known hypersensitivity to diclofenac or serratiopeptidase"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol and smoking.","Do not exceed prescribed dose or duration.","Use caution in elderly patients due to increased risk of side effects.","Monitor for signs of bleeding, especially if on anticoagulants.","Consult doctor before use if you have heart, kidney, or liver disease.","Do not use for minor aches without medical advice.","Keep out of reach of children."]

🤱 Lactation Safety

Diclofenac is excreted in breast milk in small amounts. Serratiopeptidase safety during lactation is not established. Consult your doctor before use.

💊 Overdose Management

Overdose may cause severe abdominal pain, vomiting, bleeding, drowsiness, and kidney failure. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be given if within 1-2 hours of ingestion. Monitor vital signs and renal function.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach irritation. Avoid alcohol and smoking while on this medicine. Do not take other NSAIDs or pain relievers without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, asthma, or bleeding disorders. Use the lowest effective dose for the shortest possible time. Do not use this medicine for minor aches or without a prescription. Keep out of reach of children. Store at room temperature away from moisture and sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. Diclofenac is generally avoided in the third trimester. Serratiopeptidase safety in pregnancy is not established.

🏥 Post-Surgery Considerations

This medicine may be prescribed after surgery to reduce pain and swelling. Use as directed by your surgeon. Inform your surgeon about all medicines you are taking.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may advise stopping it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Avoid smoking and excessive alcohol.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase pain and swelling. Consult your doctor before starting any exercise program. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Eat plenty of fruits and vegetables
Limit salt and sugar

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Inform your employer if your work involves operating machinery.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach pain, black stools, vomiting blood, chest pain, difficulty breathing, or signs of an allergic reaction. Do not stop abruptly without consulting your doctor if you have been on long-term therapy.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal ulcers, bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is advised. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Hot/cold compresses

May help reduce swelling and pain.

Evidence: Moderate
Acupuncture

Some evidence for pain relief in arthritis.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with post-operative swelling after knee surgery
Was prescribed this medicine for 5 days after surgery. Swelling reduced noticeably by day 3. He was advised to avoid alcohol and monitor for any signs of bleeding.
💡 Lesson: Short-term use under medical supervision can effectively manage post-operative inflammation.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Diclofenac starts relieving pain within 30-60 minutes, while serratiopeptidase may take several hours to days to reduce swelling.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe for long-term use?

A: Long-term use should be under medical supervision due to risks of gastrointestinal, kidney, and cardiovascular side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for riaser d 10mg/50mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure arthritis.
    Fact: It only relieves symptoms; it does not cure the underlying condition.
  • Myth: More tablets mean faster relief.
    Fact: Taking more than prescribed increases the risk of serious side effects without added benefit.
  • Myth: It is safe to take with other painkillers.
    Fact: Combining with other NSAIDs can increase the risk of bleeding and kidney problems.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac 10 mg + Serratiopeptidase 50 mg tablet

Brand Alternatives

  • Riaser D 10mg/50mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Diclofenac 10 mg + Serratiopeptidase 50 mg","strength":"10 mg + 50 mg","dosage_form":"Tablet","route":"Oral"},{"medicine":"Diclofenac 50 mg + Serratiopeptidase 10 mg","composition":"Diclofenac 50 mg + Serratiopeptidase 10 mg","strength":"50 mg + 10 mg","dosage_form":"Tablet","route":"Oral"},{"medicine":"Aceclofenac 100 mg + Serratiopeptidase 15 mg","composition":"Aceclofenac 100 mg + Serratiopeptidase 15 mg","strength":"100 mg + 15 mg","dosage_form":"Tablet","route":"Oral"}]

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