rexcore syrup - Terbutaline (1.25mg/5ml) + Bromhexine (2mg/5ml) medicine

Bulltus-M Syrup: Complete Medicine Guide

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🏭 Lividus Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for symptomatic relief in respiratory conditions.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Irregular heartbeat or palpitations
  • Chest pain or tightness
  • Severe dizziness or fainting
  • Muscle weakness or cramps (possible hypokalemia)
  • Yellowing of skin or eyes (jaundice)
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is rexcore syrup used for?

This medicine is a combination syrup containing terbutaline (a bronchodilator) and bromhexine (a mucolytic). It is used to relieve bronchospasm and loosen mucus in conditions like bronchitis and asthma. It works by relaxing airway muscles and thinning secretions, making breathing easier and cough more productive.

  • Generic Name: Terbutaline (1.25mg/5ml) + Bromhexine (2mg/5ml)
  • Manufacturer: Lividus Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 rexcore syrup के बारे में (Hindi Summary)

उपयोग: यह दवा टर्ब्यूटलीन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग ब्रोंकाइटिस, अस्थमा और अन्य श्वसन रोगों में बलगम को पतला करने और सांस की नली को खोलने के लिए किया जाता है। यह सांस लेने में आसानी प्रदान करती है और खांसी को उत्पादक बनाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कंपन, घबराहट, सिरदर्द, चक्कर आना, मतली और पेट की गड़बड़ी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, या दिल की धड़कन तेज हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक बढ़ाएं या घटाएं नहीं। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही मापने वाले कप या चम्मच का उपयोग करें। यदि आपको चक्कर या कंपन महसूस हो तो वाहन चलाने से बचें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 rexcore syrup Uses & Benefits

[{"condition":"Acute bronchitis","description":"Helps relieve bronchospasm and loosen mucus, making cough more productive.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Provides symptomatic relief by reducing airway constriction and thinning secretions.","evidence":"Well-established"},{"condition":"Bronchial asthma","description":"Used as an adjunct to relieve bronchospasm and mucus plugging in some patients.","evidence":"Established"},{"condition":"Productive cough with thick mucus","description":"Bromhexine helps thin and mobilize mucus, easing expectoration.","evidence":"Well-established"}]

Off-label uses: [{"condition":"COPD exacerbation","description":"Sometimes used off-label for short-term symptom relief in chronic obstructive pulmonary disease.","evidence":"Limited"}]

Primary treatment for: Respiratory conditions with bronchospasm and thick mucus (e.g., bronchitis, asthma)

Also treats: Chronic obstructive pulmonary disease (COPD), Productive cough, Emphysema

📋 Drug Information

Generic Name(s)Terbutaline (1.25mg/5ml) + Bromhexine (2mg/5ml)
Brand Namerexcore syrup
ManufacturerLividus Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight and moisture. Do not refrigerate. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always shake the bottle well before measuring the dose to ensure uniform mixing.
2
Use a proper measuring device; household spoons may not give an accurate dose.
3
Take this medicine with food to minimize stomach upset.
4
Avoid caffeine and alcohol as they may worsen side effects like tremors and palpitations.
5
Do not use this medicine for more than the recommended duration without consulting your doctor.
6
If you have diabetes, monitor your blood sugar levels regularly as terbutaline can raise them.
7
Report any persistent tremors, palpitations, or nervousness to your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
✅
Wheezing and breathlessness
Terbutaline helps relieve bronchospasm.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbutaline is rapidly absorbed from the gastrointestinal tract after oral administration. Bromhexine is also well absorbed orally. Food may slightly delay absorption but does not significantly affect the extent.
DistributionTerbutaline distributes widely into body tissues, including the lungs. Bromhexine is distributed to the respiratory tract and other tissues. Both agents cross the placenta and are excreted in breast milk.
Protein BindingTerbutaline: approximately 25% bound to plasma proteins. Bromhexine: Not established from the available information.
MetabolismTerbutaline undergoes extensive first-pass metabolism in the liver, primarily by conjugation to sulfate and glucuronide. Bromhexine is metabolized in the liver to active metabolites, including ambroxol.
Half-LifeTerbutaline: approximately 3 to 4 hours. Bromhexine: approximately 1 hour (terminal half-life may be longer due to active metabolites).
ExcretionTerbutaline and its metabolites are excreted mainly in the urine. Bromhexine metabolites are excreted primarily in the urine and to a lesser extent in feces.
BioavailabilityTerbutaline oral bioavailability is approximately 10-15% due to first-pass metabolism. Bromhexine oral bioavailability is approximately 70-80%.
Onset of ActionBronchodilation from terbutaline begins within 30 minutes after oral administration. Mucolytic effect of bromhexine may take several hours to become noticeable.
Peak Plasma TimeTerbutaline: 2-4 hours. Bromhexine: 1-2 hours.
Duration of ActionTerbutaline: 4-6 hours. Bromhexine: 6-8 hours.

How It Works

This medicine combines two active ingredients with complementary actions. Terbutaline is a selective beta-2 adrenergic receptor agonist that relaxes bronchial smooth muscle by increasing cyclic AMP, leading to bronchodilation. Bromhexine is a mucolytic agent that reduces mucus viscosity by breaking down acidic mucopolysaccharide fibers, making secretions thinner and easier to cough out. Together, they help open airways and clear mucus, improving breathing and cough clearance.

Mechanism Steps

1
Terbutaline binds beta-2 receptors: Terbutaline selectively binds to beta-2 adrenergic receptors on bronchial smooth muscle cells.
2
Increased cyclic AMP: This binding activates adenylate cyclase, raising intracellular cyclic AMP levels.
3
Bronchial smooth muscle relaxation: Elevated cyclic AMP leads to relaxation of bronchial smooth muscle, widening the airways.
4
Bromhexine reduces mucus viscosity: Bromhexine breaks down acidic mucopolysaccharide fibers in mucus, lowering its thickness.
5
Enhanced mucociliary clearance: Thinner mucus is more easily moved by cilia and coughed out, clearing the airways.

💡 How to Take rexcore syrup

Strength: Each 5 ml contains Terbutaline 1.25 mg and Bromhexine 2 mg.

1Shake the bottle well before each use.
2Use the measuring cup or spoon provided to measure the correct dose.
3Take the medicine orally with or without food, but preferably with meals to reduce stomach upset.
4Swallow the syrup directly; do not mix with other liquids unless advised by your doctor.
5Wash the measuring cup after each use and keep it clean.
6Follow your doctor's instructions regarding the duration of treatment.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5-10 ml (one to two teaspoons) taken two to three times daily, or as directed by your physician. The dose may vary depending on the severity of the condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the cardiovascular effects of terbutaline. Use with caution and start with a lower dose as prescribed by the doctor.
Renal ImpairmentDose adjustment may be required in patients with severe renal impairment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentUse with caution in patients with severe hepatic impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 30 ml (6 teaspoons) in divided doses, but this may vary based on medical advice. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase nervousness and tremors.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of rexcore syrup

✅ Common Side Effects

Tremors (Common (5-10%))
Usually resolves with continued use. If bothersome, consult your doctor.
Nervousness (Common (5-10%))
Try to rest and avoid caffeine. Consult doctor if persistent.
Headache (Common (5-10%))
Take with food and stay hydrated. Use mild pain reliever if needed after consulting doctor.
Nausea (Common (5-10%))
Take with meals to reduce stomach upset.
Palpitations (Uncommon (1-5%))
Report to your doctor if persistent or accompanied by chest discomfort.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.
Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you feel irregular heartbeat, chest pain, or fainting.
Severe hypokalemia (Rare (<0.1%))
Report muscle weakness or cramps to your doctor promptly.

⚠️ Rare Side Effects

Liver enzyme elevation
Your doctor may monitor liver function if you are on long-term therapy.
Skin rash
Discontinue and consult your doctor if rash appears.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Corticosteroids Moderate
Theophylline Moderate
Antacids Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Xanthine derivatives (e.g., theophylline)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to terbutaline, bromhexine, or any component of the formulation","Severe cardiovascular disorders (e.g., severe coronary insufficiency, cardiac arrhythmias)","Hyperthyroidism","Uncontrolled diabetes mellitus","Severe hepatic or renal impairment","Children under 2 years of age (safety not established)"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular diseases, including coronary artery disease, hypertension, and arrhythmias.","May cause hypokalemia; monitor potassium levels, especially with concomitant use of diuretics or corticosteroids.","May increase blood glucose levels; diabetic patients should monitor blood sugar closely.","Use with caution in patients with hyperthyroidism.","May cause tremors and nervousness; avoid driving or operating machinery if affected.","Do not exceed the recommended dose.","Safety and effectiveness in children below 2 years have not been established.","Prolonged use may lead to tolerance to the bronchodilator effect."]

🤱 Lactation Safety

Terbutaline is excreted in breast milk and may cause tremors or increased heart rate in the infant. Bromhexine is also excreted in breast milk. Use with caution and only if prescribed by a doctor. Monitor the infant for any unusual symptoms.

💊 Overdose Management

Overdose may cause severe tachycardia, palpitations, tremors, hypokalemia, and hyperglycemia. Treatment is supportive and symptomatic. If overdose is suspected, seek immediate medical attention. Monitor cardiac function, electrolytes, and blood glucose. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Shake the bottle well before each use to ensure the medicine is evenly mixed. Use a proper measuring cup or spoon to measure the dose accurately. Avoid driving or operating heavy machinery if you feel dizzy or shaky after taking this medicine. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or liver or kidney disease. Do not use this medicine for a longer duration than recommended without consulting your doctor. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. Do not use if the syrup has changed color or contains particles.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to cardiovascular side effects like palpitations and arrhythmias. Use with caution and monitor heart rate and blood pressure regularly.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, especially if you have heart or lung conditions. It may interact with anesthetics or other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth or interact with certain dental anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Use a humidifier to keep airways moist.
😴
Stay well hydrated to help thin mucus.
💧
Practice deep breathing exercises.
🧘
Get adequate rest to support recovery.
🌞
Avoid known allergens and pollutants.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience tremors, dizziness, or palpitations. Light activity like walking may be beneficial, but consult your doctor before starting any exercise regimen.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Avoid cold and sugary drinks that may thicken mucus.
Eat a balanced diet rich in fruits and vegetables.
Limit caffeine intake.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tremors, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe to continue desk work, but take breaks if you feel shaky.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience severe side effects. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance to terbutaline's bronchodilator effect and increased risk of cardiovascular side effects. Bromhexine is generally well-tolerated, but rare liver enzyme elevations may occur. Regular monitoring of heart rate, blood pressure, potassium levels, and liver function is advised if used for prolonged periods. Do not use for longer than recommended without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and soothe airways.

Evidence: Well-established
Chest physiotherapy

Assists in clearing secretions.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, if you have a respiratory infection, consult your doctor about timing of vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep it in your carry-on luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough and wheezing. After taking it as directed for 5 days, his cough became more productive and breathing improved. He experienced mild tremors initially, which subsided after a few days.
💡 Lesson: Taking the medicine regularly and with food helps manage side effects and improves symptoms.
👤 A 50-year-old woman with chronic bronchitis
She used this medicine during exacerbations. It helped loosen her chest congestion and made breathing easier. She was advised to monitor her heart rate due to occasional palpitations.
💡 Lesson: Regular monitoring and reporting side effects to the doctor are important for safe use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Bronchodilation begins within 30 minutes, but the full mucolytic effect may take a few hours. Symptom improvement is usually noticeable within a day.

Q: Can I take this medicine with other cough syrups?

A: Do not take other cough syrups without consulting your doctor, as they may contain overlapping ingredients or interact.

Q: Is it safe to take during pregnancy?

A: Consult your doctor. It should be used only if clearly needed, as both ingredients may affect the fetus.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for rexcore syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine provides symptomatic relief but does not cure underlying lung diseases. It should be used as part of a comprehensive treatment plan.
  • Myth: It is safe to take extra doses if symptoms are severe.
    Fact: Taking more than the prescribed dose can lead to serious side effects like rapid heartbeat and tremors. Always follow your doctor's instructions.
  • Myth: This medicine is safe for children without doctor's advice.
    Fact: Pediatric dosing is not established; consult a pediatrician before giving this medicine to children.

🔄 Alternative Options

Generic Alternatives

  • Terbutaline + Bromhexine syrup (generic)

Brand Alternatives

  • Bulltus-M Syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Terbutaline + Bromhexine)","composition":"Terbutaline 1.25 mg + Bromhexine 2 mg per 5 ml","key_feature":"Combines bronchodilation with mucolysis."},{"medicine":"Ambroxol + Terbutaline","composition":"Ambroxol 15 mg + Terbutaline 1.25 mg per 5 ml","key_feature":"Ambroxol is an active metabolite of bromhexine with similar mucolytic action."},{"medicine":"Salbutamol + Bromhexine","composition":"Salbutamol 1 mg + Bromhexine 2 mg per 5 ml","key_feature":"Salbutamol is a shorter-acting bronchodilator."}]

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