refix 200mg tablet - Cefixime (200mg) medicine

Almocef 200mg Tablet: Complete Medicine Guide

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🏭 Cipla Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is refix 200mg tablet used for?

This medicine is a cephalosporin antibiotic used to treat bacterial infections of the throat, chest, urinary tract, and skin. It works by killing bacteria. Take it with food and complete the full course as prescribed.

  • Generic Name: Cefixime (200mg)
  • Manufacturer: Cipla Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 refix 200mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एक एंटीबायोटिक है जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है, जैसे गले का संक्रमण, छाती का संक्रमण, मूत्र मार्ग का संक्रमण और त्वचा का संक्रमण। यह बैक्टीरिया को मारकर काम करती है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करें, भले ही आप बेहतर महसूस करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और उल्टी शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, गंभीर दस्त और गुर्दे की समस्या शामिल हो सकती है। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। पर्याप्त पानी पिएं। शराब से बचें। यदि आपको गुर्दे की समस्या है तो डॉक्टर को बताएं। इस दवा को दूसरों के साथ साझा न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 refix 200mg tablet Uses & Benefits

[{"condition":"Upper respiratory tract infections","description":"Used to treat bacterial infections of the throat, sinuses, and ears, such as pharyngitis, sinusitis, and otitis media.","evidence":"Well-established"},{"condition":"Lower respiratory tract infections","description":"Effective against bacterial bronchitis and pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Used for uncomplicated and complicated urinary tract infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats bacterial skin infections such as cellulitis and abscesses.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"Used as a single-dose treatment for uncomplicated gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used as an alternative to doxycycline for early Lyme disease, especially in children or pregnant women.","evidence":"Limited"},{"condition":"Typhoid fever","description":"May be used in some regions where resistance patterns allow, but not first-line in many areas.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Upper respiratory tract infections, Lower respiratory tract infections, Urinary tract infections, Skin infections, Gonorrhea

📋 Drug Information

Generic Name(s)Cefixime (200mg)
Brand Namerefix 200mg tablet
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 3 generation
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full course as prescribed, even if you feel better.
3
Stay well hydrated throughout the day.
4
Avoid alcohol while taking this medicine.
5
Do not share this medicine with others.
6
Report any unusual bleeding or bruising immediately.
7
Consult your doctor if symptoms persist beyond 7 days.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Throat infection
This medicine is commonly prescribed for bacterial throat infections.
Likely Use
Urinary tract infection
This medicine is effective against many urinary pathogens.
Likely Use
Common cold
This medicine is not effective against viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract after oral administration. The bioavailability is approximately 40-50% and is not significantly affected by food, although taking it with food may reduce stomach upset. Peak plasma concentrations are typically reached within 2-4 hours after a 200mg dose.
DistributionThis medicine distributes well into various body tissues and fluids, including the respiratory tract, urinary tract, and skin. It does not penetrate the cerebrospinal fluid well enough to treat meningitis. Protein binding is moderate, approximately 65%.
Protein BindingApproximately 65% bound to plasma proteins.
MetabolismThis medicine is not significantly metabolized in the body. It is primarily excreted unchanged.
Half-LifeThe elimination half-life is approximately 3-4 hours in healthy adults with normal kidney function. It may be prolonged in patients with renal impairment.
ExcretionThis medicine is primarily excreted unchanged in the urine. About 50% of an oral dose is excreted in the urine within 24 hours. A small amount may be excreted in bile.
BioavailabilityApproximately 40-50% after oral administration.
Onset of ActionThe onset of action is typically within 1-2 hours after oral administration, but clinical improvement of infection may take 24-48 hours.
Peak Plasma Time2-4 hours after oral administration.
Duration of ActionThe duration of action is approximately 12-24 hours, allowing for once or twice daily dosing.

How It Works

This medicine works by binding to specific proteins called penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding interferes with the cross-linking of peptidoglycan chains, which are essential for the strength and rigidity of the bacterial cell wall. As a result, the bacterial cell wall becomes weak and the cell bursts, leading to bacterial death. This medicine is bactericidal, meaning it kills bacteria directly. It is effective against a wide range of gram-positive and gram-negative bacteria, but it is not effective against viruses or fungi.

Mechanism Steps

1
Binding to penicillin-binding proteins: This medicine binds to specific penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
2
Inhibition of cell wall synthesis: By binding to PBPs, this medicine inhibits the transpeptidation reaction that cross-links peptidoglycan chains, which are essential for cell wall strength.
3
Activation of autolysins: The disruption of the cell wall triggers the activation of autolytic enzymes that further degrade the cell wall.
4
Bacterial cell lysis: The weakened cell wall cannot withstand osmotic pressure, leading to cell lysis and death of the bacteria.

💡 How to Take refix 200mg tablet

Strength: 200mg immediate-release tablet.

1Take this medicine by mouth with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course even if you feel better.
6Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 200mg to 400mg per day, taken as a single dose or in two divided doses, depending on the type and severity of the infection. For uncomplicated gonorrhea, a single 400mg dose is often used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced kidney function and may require dose adjustment. Your doctor will determine the appropriate dose based on your renal function.
Renal ImpairmentIn patients with renal impairment, the dose of this medicine should be adjusted. For creatinine clearance (CrCl) 20-40 mL/min, a dose of 200mg once daily is recommended. For CrCl less than 20 mL/min, a dose of 200mg every 48 hours is recommended. Close monitoring is advised.
Hepatic ImpairmentNo specific dose adjustment is required for patients with hepatic impairment. However, use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 400mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase side effects like nausea and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of refix 200mg tablet

✅ Common Side Effects

Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if severe or persistent.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if it persists.
Stomach pain (Common (5-10%))
Take with food. If pain is severe, contact your doctor.
Headache (Uncommon (1-5%))
Rest and stay hydrated. Consult doctor if headache is severe or persistent.
Vomiting (Uncommon (1-5%))
Take with food and drink fluids. If vomiting is severe, contact your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face or throat, difficulty breathing, or dizziness.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you have severe diarrhea that does not go away, or if you see blood or mucus in your stool.
Kidney problems (Rare (<0.1%))
Contact your doctor if you notice decreased urine output, swelling in your legs, or fatigue.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Seek immediate medical attention if you develop a rash with blisters, peeling skin, or sores in your mouth or eyes.

⚠️ Rare Side Effects

Blood disorders (e.g., thrombocytopenia, leukopenia)
Report any unusual bleeding, bruising, or signs of infection to your doctor.
Liver enzyme elevation
Your doctor may monitor liver function. Report yellowing of skin or eyes.
Seizures
Seek immediate medical attention if seizures occur, especially in patients with kidney problems.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Carbamazepine Major
Probenecid Moderate
Oral contraceptives Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Carbamazepine

⚡ Moderate Interactions

  • Probenecid
  • Oral contraceptives

🍷 Alcohol Interaction

Alcohol may worsen side effects such as nausea, dizziness, and stomach upset. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cefixime or other cephalosporin antibiotics.","History of severe allergic reaction to penicillin.","Use in patients with a history of Clostridium difficile-associated diarrhea."]

⚠️ Warnings & Precautions

["Use with caution in patients with kidney disease; dose adjustment may be needed.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use for viral infections; it is ineffective and may promote resistance.","Complete the full course as prescribed, even if symptoms improve.","May reduce the effectiveness of oral contraceptives; use backup contraception.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Avoid alcohol while taking this medicine."]

🤱 Lactation Safety

This medicine is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, stomach pain, and diarrhea. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases, especially in patients with renal impairment.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop taking it early, even if you feel better. Complete the full course to ensure the infection is fully treated. Take this medicine with food to reduce stomach upset. Drink plenty of water while taking this medicine. Avoid alcohol as it may worsen side effects like nausea and dizziness. Inform your doctor if you have kidney problems, as the dose may need adjustment. Do not share this medicine with others, even if they have similar symptoms. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require dose adjustment. Close monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe, but your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your doctor's instructions carefully.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with other medications or affect the procedure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy diet to support your immune system.
🥗
Stay well hydrated to help flush out bacteria.
😴
Get adequate rest to aid recovery.
💧
Practice good hygiene to prevent reinfection.
🧘
Avoid close contact with others if you have a contagious infection.

🏋️ Exercise Considerations

If you experience dizziness or fatigue while taking this medicine, avoid strenuous exercise or operating heavy machinery until you know how it affects you.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to help maintain gut health.
Stay well hydrated.
Avoid alcohol.
Eat a balanced diet to support recovery.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating machinery. Otherwise, it should not significantly impact your daily activities.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to antibiotic resistance and an increased risk of Clostridium difficile-associated diarrhea. Regular monitoring of kidney function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other antibiotics

Depending on the infection and susceptibility, other antibiotics may be used.

Evidence: Well-established
Supportive care

Rest, fluids, and symptomatic treatment can complement antibiotic therapy.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are scheduled for a vaccine, inform your doctor that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue taking it at the same intervals as prescribed. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a urinary tract infection. She took it with food as advised and completed the 7-day course. Her symptoms improved within 3 days, and she felt completely better by the end of the course. She experienced mild nausea initially, which went away after taking it with meals.
💡 Lesson: Taking this medicine with food reduces stomach upset and completing the full course ensures the infection is fully treated.
👤 A 50-year-old man with a respiratory tract infection
He was prescribed this medicine for bronchitis. He initially felt better after 2 days and wanted to stop, but his doctor advised him to complete the full course. He did so and recovered fully without any recurrence. He reported mild diarrhea, which resolved after finishing the medicine.
💡 Lesson: Stopping antibiotics early can lead to recurrence and resistance. Always complete the prescribed course.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, taking it with food can help reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe to take this medicine during pregnancy?

A: It is generally considered safe, but you should consult your doctor before taking any medicine during pregnancy.

Q: Can I stop taking this medicine if I feel better?

A: No, you must complete the full course to prevent the infection from returning and to avoid antibiotic resistance.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for refix 200mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the flu.
    Fact: This medicine only treats bacterial infections and is ineffective against viruses.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full course to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription antibiotic and should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Cefixime 200mg tablet

Brand Alternatives

  • Almocef 200mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Cefixime","class":"Third-generation cephalosporin","spectrum":"Broad-spectrum","typical_dose":"200-400mg/day","notes":"Good gram-negative coverage."},{"medicine":"Cefpodoxime","class":"Third-generation cephalosporin","spectrum":"Broad-spectrum","typical_dose":"200-400mg/day","notes":"Similar spectrum to cefixime."},{"medicine":"Amoxicillin-clavulanate","class":"Penicillin + beta-lactamase inhibitor","spectrum":"Broad-spectrum","typical_dose":"625mg twice daily","notes":"Better gram-positive coverage."}]

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