raizoglip 50mg tablet - Vildagliptin (50mg) medicine

Galvus 50mg Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Kotak Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High for glycemic control in type 2 diabetes.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe abdominal pain that may radiate to the back, with or without vomiting
  • Swelling of the face, lips, tongue, or throat, or difficulty breathing
  • Yellowing of the skin or eyes, dark urine, or persistent nausea
  • Signs of severe hypoglycemia: confusion, shakiness, sweating, blurred vision
  • Sudden weight gain or swelling in the legs or ankles
  • Persistent headache or dizziness that interferes with daily activities

If experiencing severe symptoms, call emergency services immediately.

What is raizoglip 50mg tablet used for?

This medicine contains vildagliptin 50 mg, a DPP-4 inhibitor used to treat type 2 diabetes. It works by increasing incretin hormones, which help control blood sugar. It is taken orally, usually once or twice daily, and is not for type 1 diabetes or diabetic ketoacidosis.

  • Generic Name: Vildagliptin (50mg)
  • Manufacturer: Kotak Life Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 raizoglip 50mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। यह शरीर में इंसुलिन की मात्रा को बढ़ाने और लिवर द्वारा बनने वाली शुगर को कम करने में मदद करती है। इसे अकेले या मेटफॉर्मिन, सल्फोनिलयूरिया या इंसुलिन के साथ भी लिया जा सकता है। यह दवा टाइप 1 डायबिटीज या डायबिटिक कीटोएसिडोसिस के लिए नहीं है। इसे डॉक्टर के बताए अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में सिरदर्द, चक्कर आना, जी मिचलाना और पेट में हल्की परेशानी शामिल हैं। कभी-कभी हाथ-पैरों में सूजन आ सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अग्नाशयशोथ (पैन्क्रियाटाइटिस) या गंभीर एलर्जी हो सकती है। अगर पेट में तेज दर्द, सांस लेने में तकलीफ, चेहरे या गले में सूजन, या पीलिया जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को अपने आप न बदलें और न ही बंद करें। इसे हर दिन एक ही समय पर लें। अगर खुराक छूट जाए तो याद आते ही ले लें, लेकिन अगली खुराक का समय नजदीक हो तो छोड़ दें। दोहरी खुराक न लें। शराब का सेवन कम करें। ब्लड शुगर की नियमित जांच करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 raizoglip 50mg tablet Uses & Benefits

[{"condition":"Type 2 diabetes mellitus","description":"Improves blood sugar control in adults when used alone or with other diabetes medicines such as metformin, sulfonylureas, or insulin.","evidence":"Well-established"},{"condition":"Type 2 diabetes with chronic kidney disease","description":"May be used with dose adjustment in patients with mild to moderate renal impairment, but not recommended in severe renal impairment.","evidence":"Established"}]

Off-label uses: [{"condition":"Prediabetes","description":"Sometimes prescribed off-label to delay progression to type 2 diabetes, but this is not a standard approved use.","evidence":"Limited"}]

Primary treatment for: Type 2 diabetes mellitus

Also treats: Chronic kidney disease (mild to moderate), Obesity, Dyslipidemia, Hypertension

📋 Drug Information

Generic Name(s)Vildagliptin (50mg)
Brand Nameraizoglip 50mg tablet
ManufacturerKotak Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassDPP-4 inhibitors
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep in the original container, tightly closed, away from moisture and direct sunlight. Do not refrigerate or freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization (WHO) includes DPP-4 inhibitors such as vildagliptin in its essential medicines list for the treatment of type 2 diabetes in certain settings. However, specific recommendations should be based on local guidelines and patient factors.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) guidelines for the management of type 2 diabetes recognize DPP-4 inhibitors as an option for monotherapy or combination therapy, especially when hypoglycemia risk is a concern. However, metformin remains the first-line therapy.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Monitor your blood sugar regularly and keep a log to share with your doctor.
3
Follow a healthy diet and exercise plan as advised by your healthcare provider.
4
Report any severe abdominal pain, which may be a sign of pancreatitis.
5
Inform your doctor if you have kidney or liver problems before starting this medicine.
6
Avoid skipping doses, as this can lead to poor blood sugar control.
7
Carry a fast-acting sugar source with you in case of hypoglycemia, especially if you take insulin or sulfonylureas.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

High blood sugar levels
This medicine is prescribed to lower blood sugar in type 2 diabetes.
Likely Use
Frequent urination and excessive thirst
These are symptoms of high blood sugar that this medicine helps control.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Joint pain
This medicine is not a pain reliever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed after oral administration. The absolute bioavailability is approximately 85%. Food does not significantly affect the extent of absorption, but the peak plasma concentration may be slightly delayed when taken with food.
DistributionThis medicine distributes widely into body tissues. It does not bind extensively to plasma proteins. The volume of distribution is approximately 71 liters.
Protein BindingThis medicine has low plasma protein binding, approximately 9.3%.
MetabolismThis medicine is not extensively metabolized in humans. The main metabolite is inactive and is formed by hydrolysis. It does not significantly inhibit or induce cytochrome P450 enzymes.
Half-LifeThe elimination half-life of this medicine is approximately 2 to 3 hours.
ExcretionThis medicine is primarily excreted unchanged in the urine, with about 85% of the dose recovered in urine and 15% in feces.
BioavailabilityThe absolute bioavailability of this medicine is approximately 85%.
Onset of ActionThis medicine begins to lower blood sugar within 1 to 2 hours after oral administration, but the full effect on blood sugar control may take several days to weeks of regular use.
Peak Plasma TimeThe peak plasma concentration of this medicine is reached approximately 1 to 2 hours after oral administration.
Duration of ActionThe blood sugar-lowering effect of this medicine lasts for about 24 hours, allowing once-daily or twice-daily dosing depending on the prescribed regimen.

How It Works

This medicine works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This enzyme normally breaks down incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By blocking DPP-4, this medicine increases the levels of these hormones, which then stimulate the pancreas to release more insulin when blood sugar is high and reduce the release of glucagon, a hormone that raises blood sugar. This leads to better blood sugar control without causing low blood sugar when used alone.

Mechanism Steps

1
Inhibition of DPP-4 enzyme: This medicine binds to and inhibits the DPP-4 enzyme, preventing it from breaking down incretin hormones.
2
Increased incretin levels: As a result, the levels of active GLP-1 and GIP increase in the bloodstream.
3
Enhanced insulin secretion: Higher incretin levels stimulate the beta cells of the pancreas to release more insulin when blood sugar is elevated.
4
Suppression of glucagon release: Incretins also reduce the secretion of glucagon from alpha cells, which decreases sugar production by the liver.
5
Improved blood sugar control: The combined effect leads to lower blood sugar levels, especially after meals, without causing hypoglycemia when used alone.

💡 How to Take raizoglip 50mg tablet

Strength: Vildagliptin 50 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You can take it with or without food.
4Take it at the same time each day to help you remember.
5Do not crush, chew, or break the tablet unless your doctor advises otherwise.
6If you miss a dose, follow the missed dose instructions.
7Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 50 mg taken once or twice daily, depending on your blood sugar levels and kidney function. When used alone, the recommended dose is 50 mg once daily. When used with other diabetes medicines such as metformin or a sulfonylurea, the dose may be 50 mg twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced kidney function. The dose should be adjusted based on renal function. No dose adjustment is needed solely based on age, but regular monitoring of kidney function is advised.
Renal ImpairmentFor patients with mild renal impairment (creatinine clearance ≥50 mL/min), no dose adjustment is needed. For moderate renal impairment (creatinine clearance 30-49 mL/min), the dose should be reduced to 50 mg once daily. This medicine is not recommended for patients with severe renal impairment (creatinine clearance <30 mL/min) or those on dialysis.
Hepatic ImpairmentThis medicine is not recommended for patients with severe hepatic impairment. For patients with mild to moderate hepatic impairment, no dose adjustment is needed, but liver function should be monitored. Use with caution.
Maximum Daily DoseThe maximum recommended daily dose is 100 mg (50 mg twice daily).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
Alcohol
Limit or avoid
May increase risk of hypoglycemia and worsen diabetes control.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of raizoglip 50mg tablet

✅ Common Side Effects

Headache (Common (1-10%))
Usually resolves on its own. Rest and hydration may help. Consult your doctor if it persists or becomes severe.
Dizziness (Common (1-10%))
Avoid driving or operating machinery if you feel dizzy. Consult your doctor if it continues.
Nausea (Common (1-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Peripheral edema (Uncommon (0.1-1%))
Elevate your legs and reduce salt intake. Consult your doctor if swelling worsens.
Constipation (Uncommon (0.1-1%))
Increase fiber and fluid intake. Consult your doctor if it persists.

🚨 Serious Side Effects

Pancreatitis (Rare (<0.1%))
Seek immediate medical attention if you experience severe abdominal pain that may radiate to your back, with or without vomiting.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you develop rash, itching, swelling of the face, lips, tongue, or throat, or difficulty breathing.
Liver injury (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or persistent nausea to your doctor immediately.
Severe hypoglycemia (Uncommon when used with insulin or sulfonylureas)
If you experience shakiness, sweating, confusion, or blurred vision, check your blood sugar and treat with fast-acting sugar. Seek medical help if symptoms persist.

⚠️ Rare Side Effects

Angioedema
Seek emergency medical care if you develop swelling of the face, lips, or throat.
Bullous pemphigoid
Report any blistering skin rash to your doctor immediately.
Hepatic enzyme elevation
Your doctor may monitor liver enzymes. Report any symptoms of liver problems.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Insulin Major
Sulfonylureas Major
Thiazolidinediones Moderate
ACE inhibitors Moderate
Digoxin Minor

🚨 Major Interactions

  • Insulin
  • Sulfonylureas (e.g., glimepiride, gliclazide)

⚡ Moderate Interactions

  • Thiazolidinediones (e.g., pioglitazone)
  • ACE inhibitors (e.g., ramipril)

🍷 Alcohol Interaction

Alcohol may increase the risk of low blood sugar and can worsen diabetes control. It is advisable to limit or avoid alcohol while taking this medicine. If you choose to drink, do so in moderation and always with food, and monitor your blood sugar closely.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to vildagliptin or any component of the formulation","Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["This medicine should not be used in patients with type 1 diabetes or diabetic ketoacidosis.","Pancreatitis has been reported; discontinue if suspected.","Liver function should be monitored; rare cases of hepatic injury have occurred.","Dose adjustment is needed in renal impairment.","Hypoglycemia risk increases when used with insulin or sulfonylureas.","Not recommended during pregnancy or breastfeeding.","Avoid excessive alcohol consumption.","Do not share this medicine with others."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother.

💊 Overdose Management

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe hypoglycemia, nausea, and abdominal pain. Treatment is supportive and symptomatic. Hemodialysis does not effectively remove this medicine from the body.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Take it with or without food, but try to take it at the same time each day. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose. Inform your doctor if you have kidney or liver problems, or if you are pregnant, planning to become pregnant, or breastfeeding. Avoid excessive alcohol consumption while taking this medicine. Check your blood sugar regularly as advised. Carry a source of fast-acting sugar with you in case of low blood sugar. Do not share this medicine with anyone else, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function. Dose adjustment based on renal function is necessary. Regular monitoring of kidney function and blood sugar is advised. This medicine is generally well-tolerated in the elderly.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before starting or continuing this medicine. It is not recommended during pregnancy. Your doctor may switch you to a safer alternative, such as insulin.

🏥 Post-Surgery Considerations

After surgery, blood sugar levels can be unpredictable. Inform your surgeon and anesthesiologist that you are taking this medicine. Your doctor may adjust your dose or temporarily switch to insulin. Do not take this medicine without medical advice after surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. There is no specific contraindication for dental procedures, but maintain good oral hygiene and monitor blood sugar as stress from dental work can affect levels.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to improve blood sugar control.
🥗
Engage in regular physical activity, such as brisk walking for 30 minutes most days.
😴
Follow a balanced diet rich in fiber, vegetables, and whole grains.
💧
Limit intake of sugary drinks and processed foods.
🧘
Monitor your blood sugar regularly as advised by your doctor.
🌞
Get adequate sleep and manage stress effectively.
🚭
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Exercise is encouraged as part of diabetes management. However, if you take insulin or sulfonylureas along with this medicine, be aware that exercise can increase the risk of hypoglycemia. Check your blood sugar before and after exercise and carry a fast-acting sugar source.

🥗 Diet Recommendations

Include high-fiber foods like whole grains, legumes, and vegetables.
Choose lean proteins such as fish, poultry, and tofu.
Limit saturated and trans fats.
Reduce salt intake to manage blood pressure.
Stay well hydrated with water.
Eat small, frequent meals to help control blood sugar.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. If you experience dizziness, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it should not significantly impact your daily work or activities. Maintain regular meal times and take your medicine as prescribed.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as pancreatitis, severe allergic reactions, or liver problems, your doctor may advise you to stop. Always follow your doctor's guidance.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well-tolerated. However, regular monitoring of kidney and liver function is advised. Rare cases of pancreatitis and liver injury have been reported. It does not cause weight gain and has a low risk of hypoglycemia when used alone. Continue lifestyle modifications for best results.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Metformin

Often the first-line medicine for type 2 diabetes. It improves insulin sensitivity and lowers blood sugar.

Evidence: Well-established
SGLT2 inhibitors

Another class of oral diabetes medicines that lower blood sugar by increasing sugar excretion in urine.

Evidence: Well-established
Lifestyle modifications

Diet and exercise are essential components of diabetes management and can complement medicine.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, people with diabetes are at higher risk of complications from infections, so ensure you are up to date with recommended vaccinations, including influenza and pneumococcal vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight and moisture

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and avoid direct sunlight. If crossing time zones, adjust the timing of your doses gradually in consultation with your doctor. Carry enough supply for the entire trip plus extra in case of delays. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with type 2 diabetes and mild kidney impairment
He was prescribed this medicine 50 mg once daily along with metformin. After 3 months, his HbA1c dropped from 8.5% to 7.2%. He experienced mild nausea initially, which resolved after taking the medicine with breakfast. He emphasized the importance of regular kidney function tests.
💡 Lesson: Adherence to the prescribed dose and regular monitoring can lead to significant improvements in blood sugar control, even with kidney issues.
👤 A 60-year-old woman with type 2 diabetes on insulin
She was started on this medicine 50 mg twice daily in addition to insulin. Her insulin dose was reduced to prevent hypoglycemia. She learned to recognize early signs of low blood sugar and always carried glucose tablets. Her blood sugar levels became more stable.
💡 Lesson: When combined with insulin, dose adjustments and close monitoring are essential to prevent hypoglycemia.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood sugar within 1 to 2 hours, but the full effect on HbA1c may take several weeks to months of regular use.

Q: Can I take this medicine with metformin?

A: Yes, this medicine is often prescribed with metformin. Your doctor will determine the appropriate dose for you.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: This medicine is not recommended during pregnancy. Consult your doctor for alternative treatments.

Q: Does this medicine cause low blood sugar?

A: When used alone, the risk of low blood sugar is low. However, when combined with insulin or sulfonylureas, the risk increases. Monitor your blood sugar closely.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Does this medicine cause weight gain?
  • Is this medicine safe for my liver?

🔄 Substitutes for raizoglip 50mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure diabetes.
    Fact: This medicine helps control blood sugar but does not cure diabetes. It must be continued along with diet and exercise.
  • Myth: This medicine causes weight gain.
    Fact: This medicine is weight-neutral and does not typically cause weight gain.
  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under a doctor's supervision.
  • Myth: This medicine can be used in type 1 diabetes.
    Fact: This medicine is not effective in type 1 diabetes and is not approved for that use.

🔄 Alternative Options

Generic Alternatives

  • Vildagliptin 50 mg tablet

Brand Alternatives

  • Galvus 50 mg tablet
  • Zomelis 50 mg tablet
  • Jalra 50 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Vildagliptin","class":"DPP-4 inhibitor","dose":"50 mg once or twice daily","renal_adjustment":"Yes","weight_effect":"Neutral","hypoglycemia_risk":"Low"},{"medicine":"Sitagliptin","class":"DPP-4 inhibitor","dose":"100 mg once daily","renal_adjustment":"Yes","weight_effect":"Neutral","hypoglycemia_risk":"Low"},{"medicine":"Metformin","class":"Biguanide","dose":"500-2000 mg daily","renal_adjustment":"Yes","weight_effect":"Weight loss","hypoglycemia_risk":"Very low"}]

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