HCQS 400 Tablet (Hydroxychloroquine 400mg): Complete Guide
When to Call Your Doctor IMMEDIATELY
- Blurred vision or vision loss
- Chest pain or irregular heartbeat
- Severe dizziness or fainting
- Signs of allergic reaction: rash, itching, swelling of face, lips, or throat
- Unusual bleeding or bruising
- Yellowing of skin or eyes
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is q-rado 400mg tablet used for?
Hydroxychloroquine 400 mg tablet is used to treat malaria and autoimmune diseases like rheumatoid arthritis and lupus. It works by killing malaria parasites and reducing inflammation. Take it with food to avoid stomach upset. Regular eye check-ups are important.
- Generic Name: Hydroxychloroquine (400mg)
- Manufacturer: El-Dorado Bio-Tech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 q-rado 400mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मलेरिया के इलाज और रोकथाम के लिए इस्तेमाल की जाती है। इसके अलावा, यह रूमेटॉइड आर्थराइटिस, ल्यूपस और स्जोग्रेन सिंड्रोम जैसी ऑटोइम्यून बीमारियों में भी प्रभावी है। यह सूजन को कम करती है और प्रतिरक्षा प्रणाली को नियंत्रित करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और धुंधली दृष्टि शामिल हैं। गंभीर दुष्प्रभावों में आंखों की रोशनी में बदलाव, दिल की धड़कन में गड़बड़ी, और एलर्जी प्रतिक्रियाएं शामिल हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन या दूध के साथ लें ताकि पेट की परेशानी कम हो। शराब का सेवन न करें। नियमित रूप से आंखों की जांच कराएं। गर्भवती होने या गर्भधारण की योजना बनाने पर डॉक्टर से सलाह लें। चक्कर आने पर वाहन न चलाएं।
💊 q-rado 400mg tablet Uses & Benefits
[{"condition":"Malaria","description":"Used for the treatment and prevention of uncomplicated malaria caused by susceptible strains of Plasmodium falciparum, vivax, ovale, and malariae.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps reduce pain and inflammation" class="semantic-link" title="Medicines for swelling">swelling and may slow joint damage in patients with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Systemic lupus erythematosus","description":"Reduces flares, skin lesions, and joint pain in lupus patients.","evidence":"Well-established"},{"condition":"Sjögren's syndrome","description":"May relieve dry eyes and mouth and reduce fatigue and joint pain.","evidence":"Moderate"},{"condition":"Porphyria cutanea tarda","description":"Can reduce skin blistering and liver enzyme abnormalities.","evidence":"Limited"}]
Off-label uses: [{"condition":"Q fever","description":"Sometimes used as part of combination therapy for chronic Q fever.","evidence":"Limited"},{"condition":"Sarcoidosis","description":"May be used to treat skin and joint symptoms of sarcoidosis.","evidence":"Limited"},{"condition":"Antiphospholipid syndrome","description":"May reduce the risk of blood clots in some patients.","evidence":"Limited"}]
Primary treatment for: Malaria
Also treats: Rheumatoid arthritis, Systemic lupus erythematosus, Sjögren's syndrome
📋 Drug Information
| Generic Name(s) | Hydroxychloroquine (400mg) |
| Brand Name | q-rado 400mg tablet |
| Manufacturer | El-Dorado Bio-Tech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Hydroxychloroquine is recommended by the World Health Organization for the treatment of uncomplicated malaria in areas where the parasite is susceptible. It is also used for autoimmune diseases per specialist guidelines. |
| ICMR Guideline | The Indian Council of Medical Research recommends hydroxychloroquine for the treatment of uncomplicated malaria and for certain autoimmune conditions, with regular monitoring. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Hydroxychloroquine works by accumulating in acidic cellular compartments such as lysosomes and endosomes. In malaria, it interferes with the parasite's ability to break down hemoglobin, leading to toxic accumulation of heme and parasite death. In autoimmune diseases, it reduces the activation of immune cells, decreases the production of inflammatory cytokines, and stabilizes lysosomal membranes, thereby reducing inflammation and tissue damage.
Mechanism Steps
💡 How to Take q-rado 400mg tablet
Strength: 400 mg immediate-release tablet
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. For malaria treatment, a common regimen is 800 mg initially, followed by 400 mg at 6, 24, and 48 hours. For malaria prevention, 400 mg once weekly. For autoimmune diseases, 200-400 mg daily. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially retinal toxicity and cardiac effects. Dose should be individualized by a clinician. |
| Renal Impairment | Dose adjustment may be needed in patients with severe renal impairment. Consult your doctor. |
| Hepatic Impairment | Dose adjustment may be needed in patients with hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose should not exceed 400 mg unless otherwise directed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of q-rado 400mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Digoxin | Major | |
| Methotrexate | Major | |
| Insulin | Major | |
| Amiodarone | Major | |
| Antacids | Moderate | |
| Cimetidine | Moderate | |
| Rifampicin | Moderate | |
| Ampicillin | Minor | |
| Neostigmine | Minor | |
| Warfarin | Moderate |
🚨 Major Interactions
- Digoxin
- Methotrexate
- Antidiabetic drugs (e.g., insulin, sulfonylureas)
- QT-prolonging drugs (e.g., amiodarone, sotalol, azithromycin)
⚡ Moderate Interactions
- Antacids
- Cimetidine
- Rifampicin
🍷 Alcohol Interaction
Alcohol may increase the risk of liver problems and stomach bleeding. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to hydroxychloroquine or any component of the formulation","Pre-existing retinopathy or visual field changes attributable to hydroxychloroquine","Use in patients with a history of severe cardiac arrhythmias","Concurrent use with QT-prolonging drugs (relative contraindication)"]
⚠️ Warnings & Precautions
["Perform baseline and periodic ophthalmologic examinations to detect retinal toxicity.","Use with caution in patients with liver or kidney disease; dose adjustment may be needed.","Monitor blood glucose closely in patients with diabetes; hydroxychloroquine may cause hypoglycemia.","May cause QT prolongation; use with caution in patients with cardiac disease or electrolyte imbalances.","Avoid in patients with known G6PD deficiency due to risk of hemolysis.","Do not use for long-term treatment without regular monitoring.","Inform patients about the risk of visual disturbances and the need to report them promptly."]
🤱 Lactation Safety
Hydroxychloroquine passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor before use.
💊 Overdose Management
Overdose of hydroxychloroquine can be life-threatening, causing severe cardiac toxicity, hypotension, and seizures. Seek immediate medical attention. Treatment is supportive and may include activated charcoal, mechanical ventilation, and medications to support blood pressure and heart rhythm. Hemodialysis is not effective.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Take with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it may increase the risk of liver problems. Inform your doctor if you have a history of eye disease, heart problems, liver or kidney disease, or blood disorders. Regular eye check-ups are essential, especially if you are on long-term therapy. Use effective contraception during treatment and consult your doctor if you plan to become pregnant. Do not drive or operate heavy machinery if you experience dizziness or blurred vision. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of retinal toxicity and cardiac side effects. Regular monitoring is essential.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor. This medicine is generally considered safe during pregnancy, but the dose may need adjustment.
🏥 Post-Surgery Considerations
Inform your surgeon that you are taking this medicine. It may affect wound healing and increase the risk of bleeding.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may increase the risk of bleeding during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience muscle weakness or pain, avoid strenuous exercise and consult your doctor. Low-impact exercises like walking and swimming are generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or blurred vision, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of retinal toxicity, which may be irreversible. Regular eye examinations are essential. It can also cause muscle weakness, heart problems, and blood disorders. Monitoring of liver and kidney function is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedAnti-inflammatory diet may help reduce symptoms.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the immune response to vaccines. Consult your doctor about the timing of vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. If you are crossing time zones, adjust your dosing schedule as advised by your doctor. Store it at room temperature and protect it from direct sunlight. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: For malaria, it starts working within hours to days. For autoimmune diseases, it may take 6-12 weeks to see full effect.
A: Yes, take it with food or milk to reduce stomach upset.
A: Avoid alcohol and grapefruit. Also, avoid driving if you feel dizzy.
🤔 Common Patient Concerns
🔄 Substitutes for q-rado 400mg tablet
View AllAlternative brands with exact same active ingredient:
-
hq 400mg tabletVasu Organics Pvt Ltd ₹96.56 9.2% COSTLIER
-
hydrowin 400mg tabletIkon Remedies Pvt Ltd ₹99.62 12.7% COSTLIER
-
ra quin 400mg tabletSun Pharmaceutical Industries Ltd ₹107.81 21.9% COSTLIER
-
rhq 400 mg tabletAbbott ₹108.56 22.8% COSTLIER
-
vohq 400mg tabletVasu Organics Pvt Ltd ₹111.23 25.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Hydroxychloroquine is a cure for COVID-19.
Fact: Hydroxychloroquine is not approved for the treatment of COVID-19. Clinical trials have not shown consistent benefit. - Myth: Hydroxychloroquine is safe for everyone.
Fact: It can cause serious side effects, especially with long-term use, and is not suitable for people with certain eye or heart conditions. - Myth: You can stop taking hydroxychloroquine once you feel better.
Fact: You should complete the full course as prescribed, especially for malaria, to prevent recurrence.
🔄 Alternative Options
Generic Alternatives
- Hydroxychloroquine sulfate 400 mg tablet
Brand Alternatives
- HCQS 400 Tablet
- Zy-Q 400 Tablet
- Hydroxychloroquine 400 mg Tablet