Gestonorm 50mg Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden shortness of breath or chest pain
- Severe headache with visual changes
- Swelling or pain in an arm or leg
- Yellowing of skin or eyes
- Severe abdominal pain
- Allergic reactions such as rash, itching, or swelling of face, lips, or throat
If experiencing severe symptoms, call emergency services immediately.
What is progestil 50mg injection used for?
This medicine is a syrup containing natural micronized progesterone 50mg. It is used to treat progesterone deficiency, support early pregnancy, and regulate menstrual cycles. It works by binding to progesterone receptors. Common side effects include drowsiness and dizziness. Take as prescribed by your doctor.
- Generic Name: Progesterone (Natural Micronized) (50mg)
- Manufacturer: Macwin Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 progestil 50mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा प्राकृतिक माइक्रोनाइज्ड प्रोजेस्टेरोन का सिरप है, जिसका उपयोग प्रोजेस्टेरोन की कमी से होने वाली समस्याओं जैसे अनियमित मासिक धर्म, गर्भपात का खतरा, और बांझपन के इलाज में ल्यूटियल फेज सपोर्ट के लिए किया जाता है। यह दवा प्रोजेस्टेरोन रिसेप्टर्स से जुड़कर शरीर में प्रोजेस्टेरोन के स्तर को संतुलित करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, सिरदर्द, स्तनों में कोमलता, और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, रक्त के थक्के, और यकृत की समस्या हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं, या स्तनपान करा रही हैं, तो अपने डॉक्टर को बताएं। यकृत रोग, रक्त के थक्के, या असामान्य योनि रक्तस्राव के इतिहास वाले मरीजों को यह दवा नहीं लेनी चाहिए।
💊 progestil 50mg injection Uses & Benefits
[{"condition":"Threatened miscarriage","description":"Used to support early pregnancy in women with progesterone deficiency.","evidence":"Well-established"},{"condition":"Luteal phase support in infertility","description":"Given to support the luteal phase in assisted reproductive technology cycles.","evidence":"Well-established"},{"condition":"Menstrual irregularities","description":"Helps regulate menstrual cycles in women with progesterone deficiency.","evidence":"Well-established"},{"condition":"Secondary amenorrhea","description":"Used to induce menstruation in women with absent periods due to progesterone deficiency.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Preterm birth prevention","description":"Sometimes prescribed off-label to prevent preterm birth in high-risk pregnancies.","evidence":"Limited"},{"condition":"Hormone replacement therapy","description":"May be used off-label as part of hormone replacement therapy in menopausal women.","evidence":"Limited"}]
Primary treatment for: Progesterone deficiency
Also treats: Threatened miscarriage, Luteal phase defect, Menstrual irregularities, Secondary amenorrhea
📋 Drug Information
| Generic Name(s) | Progesterone (Natural Micronized) (50mg) |
| Brand Name | progestil 50mg injection |
| Manufacturer | Macwin Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Natural Progesterone |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to and activating progesterone receptors in target tissues such as the endometrium, myometrium, and mammary glands. This leads to changes in gene expression that prepare the endometrium for implantation, maintain pregnancy, and regulate the menstrual cycle. It also has effects on the central nervous system, contributing to its sedative properties.
Mechanism Steps
💡 How to Take progestil 50mg injection
Strength: Syrup, 50mg per dose
Dosage Information
| Adult Dosage | The dosage of this medicine is individualized by a qualified clinician based on the indication, age, weight, and hepatic function. For threatened miscarriage, a common dose is 200-400 mg daily in divided doses. For luteal support, 200-300 mg daily may be used. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dosage adjustments are recommended for elderly patients, but use with caution due to potential for increased side effects. |
| Renal Impairment | No specific dosage adjustments are recommended for renal impairment, but use with caution. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is determined by the prescribing clinician based on the indication and patient factors. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of progestil 50mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Rifampicin | Major | |
| Ketoconazole | Moderate | |
| Carbamazepine | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin
- Rifampicin
⚡ Moderate Interactions
- Ketoconazole
- Carbamazepine
🍷 Alcohol Interaction
Alcohol may increase the sedative effects of this medicine. Avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to progesterone or any component of the formulation","History of blood clots (thrombophlebitis, pulmonary embolism, etc.)","Liver disease","Undiagnosed vaginal bleeding","Known or suspected breast cancer","Missed abortion"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have a history of blood clots, liver disease, or undiagnosed vaginal bleeding.","Use with caution in patients with renal impairment.","Do not use if you are allergic to progesterone or any of the ingredients.","Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Progesterone is excreted in breast milk. Use with caution during breastfeeding. Consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose may cause nausea, vomiting, drowsiness, and dizziness. Seek immediate medical attention if you suspect an overdose. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. This medicine may cause drowsiness; avoid driving or operating heavy machinery until you know how it affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine if you have a history of blood clots, liver disease, or undiagnosed vaginal bleeding. Keep this medicine out of reach of children. Store at room temperature away from direct sunlight and moisture. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the sedative effects of this medicine. Use with caution and monitor for falls.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before starting or continuing this medicine. It may be prescribed to support early pregnancy.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before any surgery. It may need to be stopped temporarily due to the risk of blood clots.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. No specific precautions are usually needed, but it is important for them to know your medication history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It is advisable to take it at bedtime if drowsiness is significant.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will advise you on when and how to stop based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may be associated with an increased risk of blood clots, liver problems, and breast tenderness. Regular monitoring by your doctor is important. Do not use for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise can help balance hormones.
Evidence: Well-establishedCapsules, injections, or vaginal suppositories may be alternatives.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature away from direct sunlight. If traveling across time zones, adjust dosing schedule gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of action varies depending on the indication. For luteal support, effects may be seen within days; for menstrual regulation, it may take a few weeks.
A: It can be taken with or without food, but taking it with food may reduce nausea and improve absorption.
A: Yes, it is commonly prescribed during pregnancy to support early pregnancy in women with progesterone deficiency. However, it should only be used under medical supervision.
🤔 Common Patient Concerns
🔄 Substitutes for progestil 50mg injection
View AllAlternative brands with exact same active ingredient:
-
sugest 50mg injectionSanzyme Ltd ₹40.39 0.2% COSTLIER
-
neogest 50mg injectionVhb Life Sciences Inc ₹41.02 1.8% COSTLIER
-
gestonorm 50mg syrupLancer Health Care Pvt Ltd ₹42.50 5.4% COSTLIER
-
c-hop 50mg tabletCorona Remedies Pvt Ltd ₹45.94 14% COSTLIER
-
micpro 50mg injectionChandra Bhagat Pharma Pvt Ltd ₹48.00 19.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Gestonorm 50mg syrup is a contraceptive.
Fact: This medicine is not a contraceptive. It is used for progesterone deficiency and related conditions. - Myth: Gestonorm 50mg syrup can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Natural Micronized Progesterone 50mg syrup
Brand Alternatives
- Gestonorm 50mg syrup