poser 50mg/10mg tablet - Diclofenac (50mg) + Serratiopeptidase (10mg) medicine

Aldase-D 50mg/10mg Tablet: Complete Medicine Guide

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🏭 Notus Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Diclofenac is not recommended during the third trimester of pregnancy due to risk of premature closure of the ductus arteriosus and other complications. Use in early pregnancy should be avoided unless clearly needed. Serratiopeptidase safety in pregnancy is not established from the available information. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for diclofenac; limited for serratiopeptidase.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is poser 50mg/10mg tablet used for?

This medicine is a combination of diclofenac (an NSAID) and serratiopeptidase (an enzyme) used to treat pain, inflammation, and swelling in conditions like arthritis, injuries, and post-surgical recovery. It works by reducing prostaglandins and breaking down inflammatory proteins. Take it with food and avoid alcohol.

  • Generic Name: Diclofenac (50mg) + Serratiopeptidase (10mg)
  • Manufacturer: Notus Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 poser 50mg/10mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डाइक्लोफेनाक और सेरेशियोपेप्टिडेज़ का संयोजन है, जिसका उपयोग दर्द, सूजन और जलन को कम करने के लिए किया जाता है। यह गठिया, चोट, सर्जरी के बाद की सूजन और दांत दर्द में प्रभावी है। इसे भोजन के साथ लें और शराब से बचें।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट दर्द, जलन, मतली, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, गुर्दे की समस्या, यकृत विषाक्तता और हृदय संबंधी घटनाएं शामिल हैं। यदि काला मल, उल्टी में रक्त, सीने में दर्द या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आपको पेट अल्सर, गुर्दे या यकृत की बीमारी, हृदय की समस्या या अस्थमा है तो डॉक्टर को बताएं। गर्भावस्था के अंतिम तिमाही में इसका उपयोग न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 poser 50mg/10mg tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Acute musculoskeletal injuries","description":"Helps reduce pain and swelling in sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative swelling and pain","description":"Used to manage post-surgical inflammation and pain.","evidence":"Moderate"},{"condition":"Dental pain and swelling","description":"Provides relief from dental pain and reduces post-extraction swelling.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label for migraine prevention, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but not a first-line option.","evidence":"Limited"}]

Primary treatment for: Inflammatory and painful musculoskeletal conditions

Also treats: Osteoarthritis, Rheumatoid arthritis, Acute musculoskeletal injuries, Post-operative swelling, Dental pain

📋 Drug Information

Generic Name(s)Diclofenac (50mg) + Serratiopeptidase (10mg)
Brand Nameposer 50mg/10mg tablet
ManufacturerNotus Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the prescribed dose or duration without consulting your doctor.
3
Avoid alcohol completely while taking this medicine to prevent gastrointestinal bleeding.
4
If you have a history of stomach ulcers, kidney or liver disease, or heart failure, inform your doctor before starting this medicine.
5
Do not take other NSAIDs or pain relievers concurrently without medical advice.
6
Report any unusual bleeding, bruising, or dark stools immediately.
7
Stay well hydrated throughout the day to support kidney function.
8
Use the lowest effective dose for the shortest duration possible.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Swelling after injury
This medicine helps reduce swelling and inflammation.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDiclofenac is rapidly and completely absorbed from the gastrointestinal tract after oral administration. Serratiopeptidase is absorbed intact from the intestine, but its bioavailability is not well established from the available information.
DistributionDiclofenac is highly bound to plasma proteins and distributes widely into body tissues, including synovial fluid. Serratiopeptidase distribution is not established from the available information.
Protein BindingDiclofenac is approximately 99% bound to plasma proteins, primarily albumin. Serratiopeptidase protein binding is not established from the available information.
MetabolismDiclofenac is extensively metabolized in the liver by cytochrome P450 enzymes, mainly CYP2C9, to several metabolites. Serratiopeptidase is metabolized by proteolytic degradation in the body.
Half-LifeThe elimination half-life of diclofenac is approximately 1-2 hours. The elimination half-life of serratiopeptidase is not established from the available information.
ExcretionDiclofenac metabolites are excreted primarily in urine (about 65%) and bile/feces (about 35%). Serratiopeptidase excretion is not established from the available information.
BioavailabilityThe oral bioavailability of diclofenac is approximately 50-60% due to first-pass metabolism. The bioavailability of serratiopeptidase is not established from the available information.
Onset of ActionDiclofenac begins to relieve pain within 30-60 minutes after oral administration. Serratiopeptidase onset of action is not established from the available information.
Peak Plasma TimeDiclofenac reaches peak plasma concentration in about 1-2 hours after oral intake. Serratiopeptidase peak plasma time is not established from the available information.
Duration of ActionThe analgesic and anti-inflammatory effects of diclofenac last approximately 4-6 hours. The duration of action of serratiopeptidase is not established from the available information.

How It Works

Diclofenac inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the production of prostaglandins, which are mediators of pain, inflammation, and fever. Serratiopeptidase is a proteolytic enzyme that breaks down fibrin and other inflammatory proteins, thereby reducing swelling and promoting tissue repair. Together, they provide anti-inflammatory, analgesic, and anti-edema effects.

Mechanism Steps

1
COX enzyme inhibition: Diclofenac binds to and inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandins.
2
Reduced prostaglandin synthesis: Decreased prostaglandin levels lead to reduced pain, inflammation, and fever.
3
Proteolytic enzyme action: Serratiopeptidase hydrolyzes fibrin and other inflammatory proteins, reducing swelling and promoting clearance of inflammatory debris.
4
Combined anti-inflammatory effect: The combination provides both rapid symptomatic relief and enhanced resolution of inflammation and edema.

💡 How to Take poser 50mg/10mg tablet

Strength: Each tablet contains Diclofenac 50 mg and Serratiopeptidase 10 mg.

1Take the tablet with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with food or milk to reduce stomach upset.
4Follow the prescribed schedule exactly.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally one to two times daily with food, as prescribed by your doctor. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Use the lowest effective dose for the shortest duration possible.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are at increased risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney disease. Dose reduction may be necessary. Consult your doctor for individualized dosing. Not recommended in severe kidney disease.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose reduction may be necessary. Consult your doctor for individualized dosing. Not recommended in severe liver disease.
Maximum Daily DoseThe maximum recommended daily dose of diclofenac is 150 mg. For this combination, the maximum daily dose is usually two tablets (100 mg diclofenac and 20 mg serratiopeptidase). Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of poser 50mg/10mg tablet

✅ Common Side Effects

Stomach pain (Common (5-10%))
Take with food or milk. Consult doctor if persistent.
Heartburn (Common (5-10%))
Avoid spicy foods. Use antacids if needed, but consult doctor.
Nausea (Common (5-10%))
Take with food. Stay hydrated. Consult doctor if severe.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Liver toxicity (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Cardiovascular events (Rare (<0.1%))
Seek emergency care for chest pain, shortness of breath, or sudden weakness.
Severe allergic reactions (Rare (<0.1%))
Seek immediate medical help if you experience swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Blood disorders
Report unusual bruising or bleeding to your doctor.
Pancreatitis
Seek immediate care for severe abdominal pain radiating to the back.
Aseptic meningitis
Seek immediate care for severe headache, stiff neck, and fever.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
ACE inhibitors Moderate
Diuretics Moderate
Beta-blockers Moderate
SSRIs Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • Corticosteroids
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Beta-blockers
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and can worsen stomach irritation caused by diclofenac.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active peptic ulcer or gastrointestinal bleeding","Severe kidney disease","Severe liver disease","Heart failure (NYHA class III-IV)","History of asthma, urticaria, or allergic reaction to NSAIDs","Third trimester of pregnancy","Coronary artery bypass graft surgery (peri-operative period)"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not use for longer than prescribed without medical advice.","Use with caution in the elderly.","Monitor kidney and liver function during long-term use.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart failure, or asthma.","Do not take other NSAIDs concurrently.","Consult your doctor if you are pregnant or breastfeeding."]

🤱 Lactation Safety

Diclofenac is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor. Serratiopeptidase safety during lactation is not established from the available information.

💊 Overdose Management

Overdose may cause nausea, vomiting, abdominal pain, gastrointestinal bleeding, drowsiness, and kidney failure. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be used if the patient presents early. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart failure, or asthma. Use with caution in the elderly. Do not use this medicine during the last trimester of pregnancy. If you are breastfeeding, consult your doctor before use. Store at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy. Avoid use during the third trimester.

🏥 Post-Surgery Considerations

This medicine may be prescribed for post-operative pain and swelling. Follow your surgeon's instructions carefully. Monitor for signs of bleeding.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Avoid smoking and limit alcohol.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase pain or swelling. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Eat plenty of fruits and vegetables

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach bleeding, kidney problems, or allergic reactions. Do not stop abruptly if you are on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is advised. Use the lowest effective dose for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Hot/cold compresses

May help reduce swelling and pain.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established from the available information. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with post-operative swelling after knee surgery
Was prescribed this medicine for post-surgical swelling and pain. He experienced good relief in swelling within a few days. He was advised to monitor for any signs of stomach discomfort and to avoid alcohol.
💡 Lesson: This medicine can effectively reduce post-operative swelling when taken as directed, but monitoring for side effects is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Diclofenac begins to relieve pain within 30-60 minutes. Serratiopeptidase may take longer to reduce swelling.

Q: Can I take it on an empty stomach?

A: No, it should be taken with food to reduce stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take with other NSAIDs without consulting your doctor, as it increases the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for poser 50mg/10mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset and risk of ulcers.
  • Myth: It is safe to take indefinitely for chronic pain.
    Fact: Long-term use increases risk of kidney, liver, and heart problems. Use only as prescribed.
  • Myth: It can be combined with other painkillers freely.
    Fact: Combining with other NSAIDs increases risk of bleeding and kidney damage.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac 50 mg + Serratiopeptidase 10 mg tablet

Brand Alternatives

  • Aldase-D 50mg/10mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Diclofenac + Serratiopeptidase","composition":"Diclofenac 50 mg + Serratiopeptidase 10 mg","uses":"Pain, inflammation, swelling","notes":"Combination provides anti-inflammatory and anti-edema effects."},{"medicine":"Diclofenac + Paracetamol","composition":"Diclofenac 50 mg + Paracetamol 325 mg","uses":"Pain and fever","notes":"Paracetamol adds analgesic and antipyretic effect but no anti-edema action."},{"medicine":"Aceclofenac + Serratiopeptidase","composition":"Aceclofenac 100 mg + Serratiopeptidase 10 mg","uses":"Pain, inflammation, swelling","notes":"Aceclofenac may have better GI tolerability than diclofenac."}]

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