Grewia 200 Lb Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, swelling, difficulty breathing
- Bloody or severe diarrhea
- Yellowing of skin or eyes
- Severe abdominal pain
- Unusual bleeding or bruising
- Seizures
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is pencef 200 tablet used for?
This medicine is a combination of cefixime, an antibiotic, and lactobacillus, a probiotic. It is used to treat bacterial infections while helping to prevent antibiotic-associated diarrhea.
- Generic Name: Cefixime (200mg) + Lactobacillus (250Million spores)
- Manufacturer: La Penser Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 pencef 200 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्साइम और लैक्टोबैसिलस का संयोजन है। इसका उपयोग बैक्टीरियल संक्रमण जैसे श्वसन पथ संक्रमण, मूत्र पथ संक्रमण, कान संक्रमण और गले के संक्रमण के इलाज के लिए किया जाता है। लैक्टोबैसिलस आंतों में अच्छे बैक्टीरिया को बनाए रखने में मदद करता है, जिससे एंटीबायोटिक से होने वाले दस्त को कम किया जा सकता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त या लीवर की समस्या हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। दवा को भोजन के साथ लें ताकि पेट की परेशानी कम हो। अगर आपको गुर्दे की समस्या है तो डॉक्टर को बताएं। शराब न लें। यदि आपको दाने, सूजन या सांस लेने में कठिनाई हो तो तुरंत आपातकालीन चिकित्सा सहायता लें।
💊 pencef 200 tablet Uses & Benefits
[{"condition":"Respiratory tract infections","description":"Used to treat bacterial bronchitis and other respiratory infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated urinary tract infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Ear infections","description":"Prescribed for otitis media caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Throat infections","description":"Used for pharyngitis and tonsillitis when caused by susceptible bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes used off-label for bacterial diarrhea, but not a first-line choice.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Ear infections, Throat infections
📋 Drug Information
| Generic Name(s) | Cefixime (200mg) + Lactobacillus (250Million spores) |
| Brand Name | pencef 200 tablet |
| Manufacturer | La Penser Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefixime, the antibiotic component of this medicine, works by binding to specific penicillin-binding proteins inside the bacterial cell wall. This binding inhibits the final step of peptidoglycan synthesis, which is essential for the structural integrity of the bacterial cell wall. As a result, the bacteria cannot maintain their cell wall and die. Lactobacillus, the probiotic component, helps restore and maintain the natural balance of beneficial bacteria in the gastrointestinal tract, which can be disrupted by antibiotic therapy.
Mechanism Steps
💡 How to Take pencef 200 tablet
Strength: Tablet containing Cefixime 200 mg and Lactobacillus 250 million spores.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 200 mg of cefixime taken orally every 12 hours or 400 mg once daily, depending on the type and severity of the infection. The lactobacillus component is typically 250 million spores per tablet. The duration of treatment is usually 5 to 10 days, but may vary based on the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function and may require dose adjustment. Cefixime should be used with caution in the elderly, and renal function should be monitored. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For creatinine clearance (CrCl) 20-40 mL/min, the dose may be reduced to 200 mg once daily. For CrCl <20 mL/min, the dose may be reduced to 200 mg every 24 hours or less frequently. Consult a doctor for personalized dosing. |
| Hepatic Impairment | No specific dose adjustment is recommended for hepatic impairment, but caution is advised. Monitor liver function if used in patients with liver disease. |
| Maximum Daily Dose | The maximum recommended daily dose of cefixime is 400 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of pencef 200 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Carbamazepine | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Carbamazepine
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol may worsen certain side effects of this medicine, such as nausea, dizziness, and abdominal discomfort. It is advisable to avoid alcohol while taking this medicine and for a few days after completing the course.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefixime or other cephalosporin antibiotics","History of severe allergic reaction to penicillin","Use in patients with carnitine deficiency (due to lactobacillus? No, lactobacillus is safe)","Not for use in viral infections"]
⚠️ Warnings & Precautions
["Complete the full course as prescribed, even if symptoms improve.","Use with caution in patients with kidney disease; dose adjustment may be needed.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use if the tablet is expired or damaged.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Avoid alcohol during treatment.","Do not share this medicine with others."]
🤱 Lactation Safety
Cefixime is excreted in small amounts in breast milk. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks. Lactobacillus is safe for nursing mothers.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, diarrhea, and abdominal pain. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases, but cefixime is not significantly removed by dialysis.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better. Complete the full course to ensure the infection is fully cleared and to prevent resistance. Take the tablet with food to reduce stomach upset. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Inform your doctor if you have kidney problems, as dose adjustment may be needed. Avoid alcohol while taking this medicine, as it may worsen side effects. If you develop a rash, swelling, or difficulty breathing, seek emergency medical help immediately. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function and may require dose adjustment. They may also be more susceptible to side effects such as diarrhea and dizziness. Monitor renal function and hydration status.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Cefixime is generally considered safe in pregnancy, but the decision should be made by your healthcare provider.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to prevent or treat bacterial infections. Follow your surgeon's instructions regarding dosing and duration.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with other medications or affect healing. Antibiotic prophylaxis may be needed for certain dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue while taking this medicine, avoid strenuous exercise or activities requiring alertness until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating heavy machinery. Otherwise, it should not significantly impact your daily activities. Take it with food to minimize stomach upset.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately for advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use of antibiotics can lead to antibiotic resistance and disruption of gut flora. The lactobacillus component may help mitigate some gut effects, but long-term safety data are limited. Regular monitoring of kidney and liver function may be advised for extended therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help maintain gut health during antibiotic therapy.
Evidence: Well-establishedSome herbs may have antibacterial properties, but evidence is limited and they should not replace prescribed antibiotics.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics like cefixime may reduce the effectiveness of live bacterial vaccines (e.g., typhoid vaccine). Consult your doctor about vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust dosing times gradually to maintain even intervals. Check customs regulations for carrying prescription medicines. Always carry enough for your trip and a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: Yes, taking it with food can help reduce stomach upset.
A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for pencef 200 tablet
View AllAlternative brands with exact same active ingredient:
-
ceffblu lb 200mg tabletBluewaterresearch ₹130.93 27% COSTLIER
-
grewia 200 lb tabletAdvance Revive ₹144.00 39.6% COSTLIER
-
clanfix lb tabletTas Med India Pvt Ltd ₹150.00 45.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the flu.
Fact: Antibiotics only work against bacteria. This medicine is not effective against viruses. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full course to prevent the infection from returning and to avoid antibiotic resistance.
🔄 Alternative Options
Generic Alternatives
- Cefixime 200 mg + Lactobacillus 250 million spores tablet
Brand Alternatives
- Grewia 200 LB Tablet