Calcipotriol 0.005% Ointment: A Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe skin irritation, blistering, or peeling
- Signs of hypercalcaemia such as nausea, vomiting, constipation, increased thirst, or confusion
- Swelling of face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Yellowing of skin or eyes
- Severe abdominal pain
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is pasitrex ointment used for?
This medicine is a topical ointment containing calcipotriol 0.005% w/w, used to treat plaque psoriasis by slowing down rapid skin cell growth and reducing inflammation.
- Generic Name: Calcipotriol (0.005% w/w)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 pasitrex ointment के बारे में (Hindi Summary)
उपयोग: यह दवा कैल्सीपोट्रियोल 0.005% w/w युक्त एक मरहम है, जिसका उपयोग प्लाक सोरायसिस (त्वचा पर सूखे, पपड़ीदार धब्बे) के इलाज के लिए किया जाता है। यह त्वचा कोशिकाओं की तेजी से वृद्धि को धीमा करता है और सूजन को कम करता है। यह केवल बाहरी उपयोग के लिए है और इसे चेहरे, आंखों, होंठों या श्लेष्मा झिल्ली पर नहीं लगाना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में त्वचा में जलन, खुजली, जलन, लालिमा और सूखापन शामिल हैं। ये आमतौर पर हल्के होते हैं और उपयोग जारी रखने पर कम हो जाते हैं। दुर्लभ मामलों में रक्त में कैल्शियम का स्तर बढ़ सकता है, जिसके लिए डॉक्टर से परामर्श आवश्यक है।
सुरक्षा सलाह: इस दवा को केवल प्रभावित त्वचा पर ही लगाएं। आंखों, होंठों और श्लेष्मा झिल्ली से बचें। उपयोग से पहले और बाद में हाथ धोएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 pasitrex ointment Uses & Benefits
[{"condition":"Plaque psoriasis","description":"This medicine is used to treat mild to moderate plaque psoriasis, reducing scaling, thickening, and inflammation of the skin plaques.","evidence":"Well-established"},{"condition":"Scalp psoriasis","description":"It can be effective for psoriasis affecting the scalp, helping to reduce flaking and itching.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Nail psoriasis","description":"Sometimes used off-label for nail psoriasis, but evidence is limited and it is not a standard treatment.","evidence":"Limited"},{"condition":"Vitiligo","description":"Occasionally used off-label in combination with other treatments for vitiligo, but evidence is insufficient.","evidence":"Insufficient"}]
Primary treatment for: Plaque psoriasis
Also treats: Scalp psoriasis
📋 Drug Information
| Generic Name(s) | Calcipotriol (0.005% w/w) |
| Brand Name | pasitrex ointment |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Topical Vitamin D3 Analogues |
| Route of Administration | Topical |
| Storage | Store below 25°C. Do not freeze. Keep the tube tightly closed. Protect from light. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Calcipotriol binds to vitamin D receptors in the skin, leading to modulation of gene expression. This results in inhibition of keratinocyte proliferation and promotion of keratinocyte differentiation, which helps to normalise the rapid turnover of skin cells seen in psoriasis. Additionally, it exerts anti-inflammatory effects by inhibiting T-cell activation and cytokine production.
Mechanism Steps
💡 How to Take pasitrex ointment
Strength: Ointment containing calcipotriol 0.005% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected areas once or twice daily as directed by your doctor. The usual maximum weekly dose is 100 grams of ointment. The dose must be individualized by a qualified clinician based on the extent and severity of the condition, and the patient's response to treatment. Do not exceed the recommended dose or duration without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but they should use it with caution and under medical supervision. |
| Renal Impairment | Use with caution in patients with severe renal impairment due to the risk of hypercalcaemia. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with severe hepatic impairment. Consult a doctor. |
| Maximum Daily Dose | The maximum recommended weekly dose is 100 grams of ointment. Daily dose should not exceed approximately 15 grams. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of pasitrex ointment
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to calcipotriol or any component of the ointment","Disorders of calcium metabolism","Severe renal impairment","Severe hepatic impairment","Use on the face, groin, or mucous membranes (unless directed by a doctor)"]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, lips, and mucous membranes.","Do not apply to large areas of skin for prolonged periods without medical supervision.","Avoid excessive exposure to natural or artificial sunlight.","Use with caution in patients with renal or hepatic impairment.","Do not use under occlusive dressings unless instructed.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether calcipotriol is excreted in human breast milk after topical application. Because systemic absorption is low, the risk to a breastfed infant is likely low, but caution is advised. Avoid applying to the breast area to prevent infant exposure.
💊 Overdose Management
Topical overdose is unlikely to cause serious effects. If excessive amounts are applied, wash off the excess with soap and water. If ingested, seek medical attention immediately. Symptoms of hypercalcaemia may occur with systemic overdose and require supportive care and monitoring of serum calcium.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply this medicine only to the affected areas of skin as directed by your doctor. Wash your hands thoroughly before and after application unless the hands are being treated. Avoid applying to the face, eyes, lips, or mucous membranes. Do not cover the treated area with airtight dressings unless instructed. Avoid excessive sun exposure and the use of sunlamps while using this medicine. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for any condition other than the one for which it was prescribed. Keep out of reach of children. If you accidentally swallow this medicine, seek medical attention immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients should use this medicine with caution and under medical supervision, as they may be more susceptible to side effects such as skin irritation and hypercalcaemia.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
🏥 Post-Surgery Considerations
There are no specific restrictions after surgery, but avoid applying the ointment to surgical wounds or broken skin unless directed by your doctor.
🦷 Dental Procedures
No specific considerations for dental procedures. Inform your dentist about all medications you are using.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions while using this medicine. However, avoid activities that may cause excessive sweating or friction on treated areas, as this can irritate the skin.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to work or drive. However, if you experience skin irritation, it may cause some discomfort. You can continue your normal activities unless your doctor advises otherwise.
🛑 When to Stop This Medicine
Do not stop using this medicine without consulting your doctor. If you experience severe side effects or no improvement after the recommended duration, your doctor may advise stopping or changing the treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when used as directed. However, prolonged use over large areas may increase the risk of hypercalcaemia. Regular monitoring of serum calcium may be advised if used extensively. Skin atrophy and other local effects are rare but possible. It is important to have periodic reviews with your doctor to assess the continued need for treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Controlled exposure to ultraviolet light under medical supervision can help treat psoriasis.
Evidence: Well-establishedFor severe psoriasis, oral or injectable medications may be prescribed.
Evidence: Well-establishedStress can trigger psoriasis flares; relaxation techniques may help.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions between this medicine and vaccines. Continue with routine vaccinations as advised by your doctor.
📦 Storage Guide
✅ DO
Store below 25°C
❌ DON'T
Do not freeze
✅ DO
Keep the tube tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it below 25°C and protect it from light. If you are crossing time zones, continue applying it according to your usual schedule; no time adjustment is needed for topical medications. Keep it in your carry-on luggage if flying, as checked baggage may be exposed to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to see improvement in 1-2 weeks, but it usually takes 4-8 weeks for significant benefit.
A: No, unless specifically directed by your doctor. It can cause irritation on sensitive areas.
A: Common side effects include skin irritation, itching, burning, redness, and dryness at the application site. Rarely, it can cause high calcium levels.
A: Consult your doctor. It should be used during pregnancy only if clearly needed.
A: Yes, but inform your doctor about all other medications you are using. Apply them at different times as advised.
🤔 Common Patient Concerns
🔄 Substitutes for pasitrex ointment
View AllAlternative brands with exact same active ingredient:
-
calpsor ointmentBiocon ₹210.00 39% CHEAPER
-
calisor ointmentCanbro Healthcare ₹318.75 7.4% CHEAPER
-
soronil 0.005% ointmentEskon Pharma ₹325.00 5.5% CHEAPER
-
soristop ointmentAlniche Life Sciences Pvt Ltd ₹337.50 1.9% CHEAPER
-
sorifix solo ointmentLa Pristine Bioceuticals Pvt Ltd ₹388.00 12.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure psoriasis permanently.
Fact: This medicine helps control symptoms but does not cure psoriasis. Psoriasis is a chronic condition that requires ongoing management. - Myth: More ointment means faster results.
Fact: Using more than prescribed can increase the risk of side effects, including hypercalcaemia. Always follow your doctor's instructions. - Myth: This medicine is safe to use on any part of the body.
Fact: It should not be used on the face, groin, or mucous membranes unless specifically directed by a doctor, as these areas are more sensitive.
🔄 Alternative Options
Generic Alternatives
- Calcipotriol 0.005% w/w ointment (various manufacturers)
Brand Alternatives
- Daivonex
- Dovonex
- Sorilux