parasafe tablet - Paracetamol (500mg) + Racemethionine (50mg) medicine

Hepamol Tablet: Complete Medicine Guide

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🏭 Strassenburg Pharmaceuticals.Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Paracetamol: Well-established for pain and fever. Racemethionine: Limited evidence for hepatoprotection in this combination.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes
  • Dark urine or pale stools
  • Severe abdominal pain
  • Swelling of face, lips, or throat
  • Difficulty breathing
  • Unusual bleeding or bruising
  • Persistent vomiting

If experiencing severe symptoms, call emergency services immediately.

What is parasafe tablet used for?

This medicine is a combination of Paracetamol 500 mg and Racemethionine 50 mg used for short-term relief of mild to moderate pain and fever. Paracetamol reduces pain and fever, while Racemethionine may support liver glutathione. It should be taken as prescribed and not exceed the maximum daily dose of Paracetamol.

  • Generic Name: Paracetamol (500mg) + Racemethionine (50mg)
  • Manufacturer: Strassenburg Pharmaceuticals.Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 parasafe tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल 500 मिलीग्राम और रेसमेथियोनिन 50 मिलीग्राम का संयोजन है। इसका उपयोग हल्के से मध्यम दर्द जैसे सिरदर्द, शरीर दर्द, दांत दर्द और बुखार में राहत के लिए किया जाता है। पैरासिटामोल दर्द और बुखार को कम करता है, जबकि रेसमेथियोनिन लिवर में ग्लूटाथियोन को बढ़ाने में मदद कर सकता है। यह दवा डॉक्टर की सलाह के अनुसार ही लें और पैरासिटामोल की अधिकतम दैनिक मात्रा से अधिक न लें।

साइड इफेक्ट्स: आमतौर पर यह दवा सही मात्रा में लेने पर अच्छी तरह सहन की जाती है। कुछ लोगों को मतली, पेट में असहजता या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अधिक मात्रा में लेने पर लिवर को गंभीर नुकसान हो सकता है। अगर आंखों या त्वचा का रंग पीला पड़े, पेशाब गहरा हो, पेट में तेज दर्द हो या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पैरासिटामोल की अधिकतम दैनिक मात्रा से अधिक न लें और अन्य दवाओं में छिपे पैरासिटामोल की जांच करें। इस दवा के साथ शराब न लें क्योंकि इससे लिवर को नुकसान का खतरा बढ़ता है। अगर आपको लिवर या किडनी की समस्या है, या आप गर्भवती या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। बिना सलाह के कुछ दिनों से अधिक इसका उपयोग न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 parasafe tablet Uses & Benefits

[{"condition":"Mild to moderate pain","description":"Relieves headache, body ache, muscle pain, and toothache by reducing pain perception.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever by acting on the temperature-regulating center in the brain.","evidence":"Well-established"},{"condition":"Pain with liver support need","description":"Used when Paracetamol is needed and additional liver support is considered helpful, though clinical benefit of Racemethionine in this combination is not firmly established.","evidence":"Limited"}]

Off-label uses: [{"condition":"Hangover prevention","description":"Some people use this medicine after alcohol consumption, but this is not recommended and may increase liver risk.","evidence":"Not established from the available information."}]

Primary treatment for: Pain and fever

Also treats: Headache, Body ache, Toothache, Fever due to infections

📋 Drug Information

Generic Name(s)Paracetamol (500mg) + Racemethionine (50mg)
Brand Nameparasafe tablet
ManufacturerStrassenburg Pharmaceuticals.Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a dry place, away from direct sunlight. Keep in the original container.
Shelf LifeTypically 24 months from the date of manufacture. Check the expiry date on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the maximum daily dose of Paracetamol from any source.
3
Avoid alcohol completely while taking this medicine.
4
Check other medicines for Paracetamol content to prevent accidental overdose.
5
Consult your doctor if pain or fever persists for more than 3 days.
6
Report any signs of liver problems such as yellowing of eyes or dark urine immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Mild to moderate pain
This medicine is commonly used for this.
Likely Use
✅
Fever
This medicine helps reduce fever.
Likely Use
❌
Severe pain requiring strong analgesics
This medicine is not a strong painkiller.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. Racemethionine is also absorbed orally. Food may delay the peak effect of Paracetamol slightly but does not significantly reduce total absorption.
DistributionParacetamol distributes widely into body fluids and tissues. It crosses the placenta and is present in breast milk in small amounts. Racemethionine distributes to the liver and other tissues where it participates in methylation and transsulfuration pathways.
Protein BindingParacetamol is approximately 10-25% bound to plasma proteins. Racemethionine binding is not established from the available information.
MetabolismParacetamol is metabolized primarily in the liver by glucuronidation and sulfation. A small fraction is oxidized by CYP2E1 to N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified by glutathione. Racemethionine is metabolized to S-adenosylmethionine, homocysteine, and cysteine, supporting glutathione synthesis.
Half-LifeParacetamol elimination half-life is typically 2-3 hours in adults with normal liver function. Racemethionine half-life is not established from the available information.
ExcretionParacetamol metabolites are excreted mainly in urine. Racemethionine metabolites are also excreted in urine.
BioavailabilityParacetamol oral bioavailability is approximately 80-100%. Racemethionine bioavailability is not established from the available information.
Onset of ActionParacetamol usually begins to reduce pain and fever within 30-60 minutes after oral intake.
Peak Plasma TimePeak plasma concentration of Paracetamol is reached in about 30-60 minutes after oral administration. Racemethionine peak time is not established from the available information.
Duration of ActionParacetamol pain relief and fever reduction typically last 4-6 hours.

How It Works

Paracetamol reduces pain and fever mainly by inhibiting prostaglandin synthesis in the central nervous system. It acts on the hypothalamus to lower fever and on pain pathways to increase the pain threshold. Racemethionine is a precursor of S-adenosylmethionine and helps restore hepatic glutathione, which is important for detoxifying the toxic metabolite of Paracetamol, N-acetyl-p-benzoquinone imine. This may help protect the liver when Paracetamol is used at or near maximum recommended doses.

Mechanism Steps

1
Central COX inhibition: Paracetamol inhibits cyclooxygenase enzymes in the central nervous system, reducing prostaglandin synthesis.
2
Pain threshold elevation: Reduced prostaglandins increase the pain threshold, making pain less intense.
3
Hypothalamic temperature regulation: Paracetamol acts on the hypothalamus to promote heat loss and reduce fever.
4
Glutathione replenishment: Racemethionine is converted to S-adenosylmethionine and then to cysteine, supporting glutathione synthesis in the liver.
5
Detoxification support: Increased glutathione helps conjugate the toxic Paracetamol metabolite NAPQI, reducing liver injury risk.

💡 How to Take parasafe tablet

Strength: Each tablet contains Paracetamol 500 mg and Racemethionine 50 mg.

1Take the tablet by mouth with a full glass of water.
2Take it with or without food, but food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew unless advised by your doctor.
4Follow the dose and frequency recommended by your doctor.
5Do not take more than the maximum daily dose of Paracetamol from any source.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 4 to 6 hours as needed for pain or fever, not exceeding the maximum daily dose of Paracetamol. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, liver and kidney function, and other medicines being taken. Do not self-medicate for more than 3 days without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of Paracetamol and are at higher risk of liver injury. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with severe kidney impairment, the dose may need to be reduced or the dosing interval extended. Consult a doctor for individualized dosing.
Hepatic ImpairmentIn patients with liver disease, this medicine should be used with caution and at reduced doses. Consult a doctor for individualized dosing. It is contraindicated in severe liver disease.
Maximum Daily DoseThe maximum daily dose of Paracetamol is generally 4000 mg for adults, but lower limits may apply in certain conditions such as liver disease, alcohol use, or malnutrition. Do not exceed the dose recommended by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of parasafe tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food or milk to reduce nausea. Consult doctor if it persists.
Stomach discomfort (Common (1-10%))
Take after meals. Avoid alcohol. Consult doctor if pain is severe.
Skin rash (Uncommon (0.1-1%))
Stop the medicine and consult a doctor if rash appears.

🚨 Serious Side Effects

Severe liver injury (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of eyes or skin, dark urine, or severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.
Blood disorders (very rare) (Very rare (<0.01%))
Report unusual bruising, bleeding, or persistent sore throat to your doctor.

⚠️ Rare Side Effects

Thrombocytopenia
Consult doctor if you notice easy bruising or bleeding.
Leukopenia
Report frequent infections or fever to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Other Paracetamol products Major
Carbamazepine Moderate
Phenytoin Moderate
Rifampicin Moderate
Isoniazid Moderate
Metoclopramide Minor
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Other Paracetamol-containing products

⚡ Moderate Interactions

  • Carbamazepine, phenytoin, rifampicin
  • Isoniazid

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of Paracetamol-induced liver injury, especially with regular or high-dose use.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to Paracetamol or Racemethionine","Severe liver disease or active liver failure","Active alcohol dependence","Malnutrition or low glutathione states (relative contraindication)"]

⚠️ Warnings & Precautions

["Do not exceed the recommended daily dose of Paracetamol.","Avoid alcohol while taking this medicine.","Check other medicines for Paracetamol content to avoid accidental overdose.","Use with caution in patients with liver or kidney disease.","Consult a doctor if pain or fever persists for more than 3 days.","Keep out of reach of children."]

🤱 Lactation Safety

Paracetamol passes into breast milk in small amounts and is generally considered compatible with breastfeeding. Racemethionine safety during breastfeeding is not established from the available information. Consult your doctor.

💊 Overdose Management

Overdose of Paracetamol can cause severe liver damage. Symptoms may include nausea, vomiting, abdominal pain, and yellowing of skin or eyes. Seek immediate medical attention even if you feel well. Treatment with N-acetylcysteine is most effective when given early. Do not wait for symptoms to appear.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended daily dose of Paracetamol, and check other medicines you are taking to avoid hidden Paracetamol. Avoid alcohol while taking this medicine because it increases the risk of liver damage. Inform your doctor if you have liver or kidney problems, or if you are pregnant or breastfeeding. Do not use this medicine for more than a few days without medical advice. Keep it out of reach of children. If you miss a dose, follow your doctor's instructions and do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of Paracetamol and are at higher risk of liver injury. Use the lowest effective dose for the shortest duration and consult a doctor regularly.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Paracetamol is generally considered safe for short-term use, but Racemethionine safety is not established.

🏥 Post-Surgery Considerations

This medicine may be used for post-surgical pain as advised by your doctor. Do not exceed the recommended dose and avoid alcohol.

🦷 Dental Procedures

This medicine can be taken for dental pain, but inform your dentist about all medicines you are taking. Do not exceed the maximum daily dose.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated throughout the day.
🥗
Avoid alcohol completely while taking this medicine.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Get adequate rest to help your body recover.
🧘
Follow good hygiene to prevent infections that cause fever.

🏋️ Exercise Considerations

Mild exercise is generally safe while taking this medicine, but if you have fever or severe pain, rest is recommended. Avoid strenuous exercise if you feel weak or dizzy.

🥗 Diet Recommendations

Include plenty of fluids
Eat light, easily digestible meals
Avoid alcohol
Include fruits rich in vitamin C

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe for office work.

🛑 When to Stop This Medicine

Stop this medicine when your pain or fever resolves, or as advised by your doctor. Do not stop suddenly if you are taking it for a chronic condition without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine at high doses can increase the risk of liver and kidney problems. Regular monitoring of liver and kidney function may be needed if used for prolonged periods. Do not use it for more than a few days without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Rest and hydration

Adequate rest and fluids can help manage mild fever and body ache.

Evidence: Well-established
Physical therapy

Can help with chronic pain conditions.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. It can be taken before or after vaccination if needed for pain or fever, but consult your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight and moisture. If traveling across time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old office worker with fever and body ache
Ravi took this medicine as prescribed by his doctor for fever and body ache. He noticed relief within an hour and his fever subsided. He was advised to take it after food to avoid stomach discomfort and to avoid alcohol. He completed the short course and recovered well.
💡 Lesson: Taking this medicine with food and following the prescribed dose provides safe and effective relief.
👤 A 50-year-old man with occasional headaches and a history of social drinking
Mr. Sharma used this medicine for headaches but continued to drink alcohol occasionally. His doctor warned him about the increased risk of liver damage and advised him to stop alcohol completely while taking the medicine. He followed the advice and had no liver problems.
💡 Lesson: Alcohol should be strictly avoided while taking this medicine to prevent liver injury.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain and fever within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It can be taken on an empty stomach, but taking it with food may reduce stomach discomfort.

Q: Is it safe for my liver?

A: Paracetamol can harm the liver if taken in excess or with alcohol. Racemethionine may support liver glutathione, but you must not exceed the recommended dose.

Q: Can I take it with other painkillers?

A: Do not take other Paracetamol-containing products without consulting your doctor. Other painkillers may be taken only if prescribed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for parasafe tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is completely safe in any dose.
    Fact: Paracetamol can cause serious liver damage if taken in excess. Always follow the recommended dose.
  • Myth: Racemethionine makes this medicine a liver tonic.
    Fact: Racemethionine may support glutathione, but it does not make the combination a liver tonic or prevent all liver injury.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol 500 mg + Racemethionine 50 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Paracetamol 500 mg + Racemethionine 50 mg","primary_use":"Pain and fever with liver support","notes":"Racemethionine may support glutathione."},{"medicine":"Paracetamol 500 mg alone","composition":"Paracetamol 500 mg","primary_use":"Pain and fever","notes":"No additional liver support."},{"medicine":"Paracetamol + N-acetylcysteine","composition":"Paracetamol + N-acetylcysteine","primary_use":"Pain and fever with antioxidant support","notes":"N-acetylcysteine is a direct glutathione precursor."}]

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