orange n kid tablet - Nimesulide (NA) medicine

Angip Tablet (Nimesulide): Complete Medicine Guide

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🏭 Orange Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for short-term pain relief; safety concerns limit its use.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes (jaundice)
  • Dark urine or pale stools
  • Severe abdominal pain or vomiting blood
  • Black, tarry stools
  • Swelling of face, lips, or throat
  • Difficulty breathing
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is orange n kid tablet used for?

This medicine contains nimesulide, an NSAID used for short-term relief of acute pain and inflammation. It works by blocking COX-2 enzymes. It is not recommended for children under 12, during pregnancy, or in people with liver disease. Use only as prescribed, for the shortest duration possible.

  • Generic Name: Nimesulide (NA)
  • Manufacturer: Orange Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 orange n kid tablet के बारे में (Hindi Summary)

उपयोग: यह दवा निमेसुलाइड नामक सक्रिय तत्व से बनी है और यह एक दर्द निवारक तथा सूजन कम करने वाली दवा है। इसका उपयोग मुख्य रूप से जोड़ों के दर्द, मांसपेशियों के दर्द, दांत के दर्द और सूजन से जुड़े दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह बुखार कम करने में भी मदद कर सकती है, लेकिन इसे केवल डॉक्टर की सलाह पर ही लेना चाहिए। यह दवा शरीर में उन रसायनों को कम करती है जो दर्द और सूजन पैदा करते हैं। इसे खाने के साथ लेना चाहिए ताकि पेट में जलन न हो। इसे 5 दिन से ज्यादा नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, चक्कर आना और सिरदर्द शामिल हैं। ये आमतौर पर हल्के होते हैं और खाने के साथ दवा लेने पर कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें लिवर की क्षति, पेट में रक्तस्राव, गुर्दे की समस्या और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। अगर आपको आंखों या त्वचा का पीलापन, गहरे रंग का पेशाब, या लगातार पेट दर्द महसूस हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को केवल डॉक्टर की सलाह पर और कम से कम समय के लिए लें। इसे हमेशा खाने के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब बिल्कुल न लें क्योंकि इससे पेट में रक्तस्राव और लिवर की समस्या का खतरा बढ़ जाता है। अगर आपको लिवर या गुर्दे की बीमारी, दिल की समस्या, या पेट के अल्सर की हिस्ट्री है, तो डॉक्टर को बताएं। गर्भावस्था और स्तनपान के दौरान इस दवा का सेवन न करें। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 orange n kid tablet Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"This medicine provides short-term relief of pain and inflammation in muscles, tendons, and joints after injury or strain.","evidence":"Well-established"},{"condition":"Osteoarthritis pain","description":"It reduces joint pain and stiffness in osteoarthritis, but is usually reserved for short-term use when other treatments are not effective.","evidence":"Established"},{"condition":"Dental pain","description":"This medicine is used to relieve pain after dental procedures or in conditions like toothache and gum inflammation.","evidence":"Established"},{"condition":"Fever","description":"It can lower fever, but is not a first-choice medicine for this purpose due to safety concerns.","evidence":"Limited"},{"condition":"Post-operative pain","description":"Sometimes used for short-term pain relief after minor surgery, under medical supervision.","evidence":"Limited"}]

Off-label uses: [{"condition":"Migraine","description":"Occasionally used off-label for acute migraine pain, but not recommended as a first-line treatment.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but other NSAIDs are preferred.","evidence":"Limited"}]

Primary treatment for: Acute pain and inflammation

Also treats: Osteoarthritis, Dental pain, Musculoskeletal pain, Fever

📋 Drug Information

Generic Name(s)Nimesulide (NA)
Brand Nameorange n kid tablet
ManufacturerOrange Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's-Non-Selective COX 1&2 Inhibitors (Others)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach irritation.
2
Use the lowest effective dose for the shortest duration, usually not more than 5 days.
3
Avoid alcohol completely while taking this medicine.
4
Do not combine with other NSAIDs like ibuprofen or diclofenac.
5
Report any signs of liver problems such as yellowing of eyes or dark urine immediately.
6
Stay well hydrated throughout the day.
7
Consult your doctor if pain persists beyond 5 days.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Acute joint pain
This medicine is commonly prescribed for short-term relief.
Likely Use
Fever
This medicine is not a first-choice fever reducer due to safety concerns.
Not Primary
Chronic pain
Not recommended for long-term use.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNimesulide is rapidly absorbed from the gastrointestinal tract after oral administration. Food may slightly delay absorption but does not significantly reduce the total amount absorbed.
DistributionIt is widely distributed throughout the body, with a volume of distribution of approximately 0.2 L/kg. It crosses the blood-brain barrier and placenta.
Protein BindingNimesulide is highly bound to plasma proteins, primarily albumin, with a binding rate of about 99%.
MetabolismNimesulide is extensively metabolised in the liver, mainly by the cytochrome P450 enzyme CYP2C9, into several metabolites. One major metabolite, 4-hydroxynimesulide, is pharmacologically active.
Half-LifeThe elimination half-life of nimesulide is approximately 2 to 5 hours, while its active metabolite has a longer half-life of about 5 to 8 hours.
ExcretionMetabolites are excreted primarily in the urine (about 70%) and in the faeces (about 30%).
BioavailabilityThe oral bioavailability of nimesulide is approximately 80% to 90%.
Onset of ActionPain relief usually begins within 30 to 60 minutes after taking the tablet.
Peak Plasma TimePeak plasma concentration is reached about 1.5 to 3 hours after oral administration.
Duration of ActionThe analgesic and anti-inflammatory effects last for about 6 to 8 hours, so it is usually taken two to three times daily.

How It Works

This medicine works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme, which is involved in the production of prostaglandins. Prostaglandins are chemicals that cause pain, swelling, and fever. By blocking COX-2, this medicine reduces these symptoms. It has less effect on COX-1, which is why it may cause fewer stomach problems than some older NSAIDs, but it still carries risks.

Mechanism Steps

1
Absorption and distribution: After swallowing the tablet, nimesulide is absorbed into the bloodstream and distributed to tissues where inflammation is present.
2
COX-2 inhibition: Nimesulide binds to and inhibits the COX-2 enzyme, blocking the conversion of arachidonic acid into prostaglandins.
3
Reduced prostaglandins: With less prostaglandin production, pain signals are reduced, swelling decreases, and fever comes down.
4
Clinical relief: The patient experiences less pain and inflammation, usually within a few hours of taking the tablet.

💡 How to Take orange n kid tablet

Strength: Immediate-release tablet, strength not specified in the provided information.

1Take the tablet by mouth with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take it at the same times each day as prescribed.
5Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 100 mg taken twice daily, with food. The maximum recommended duration is 5 days for pain and 3 days for fever. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially stomach bleeding and kidney problems. Use with caution and at the lowest effective dose. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney disease. Dose reduction may be necessary. Consult your doctor for individualized dosing.
Hepatic ImpairmentContraindicated in patients with active liver disease. In patients with mild to moderate liver impairment, use with extreme caution and only if clearly needed. Dose must be individualized by a qualified clinician.
Maximum Daily Dose200 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of stomach bleeding and liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of orange n kid tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take the tablet with food or milk. If nausea persists, consult your doctor.
Stomach pain or heartburn (Common (5-10%))
Take with food and avoid alcohol. If pain is severe or persistent, seek medical advice.
Diarrhoea (Common (3-5%))
Stay hydrated. If diarrhoea is severe or contains blood, contact your doctor.
Dizziness (Common (3-5%))
Avoid driving or operating machinery until you know how this medicine affects you.
Headache (Common (3-5%))
Usually resolves on its own. If it persists, consult your doctor.

🚨 Serious Side Effects

Liver injury (hepatotoxicity) (Rare (<0.1%))
Stop the medicine and seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Gastrointestinal bleeding or ulcer (Rare (<0.1%))
Seek immediate medical help if you vomit blood, pass black stools, or have severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Call emergency services if you experience swelling of the face, lips, or throat, difficulty breathing, or a severe rash.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling in the legs, or unusual tiredness to your doctor.

⚠️ Rare Side Effects

Blood disorders (e.g., low platelet count)
Report unusual bruising or bleeding to your doctor immediately.
Severe skin reactions (e.g., Stevens-Johnson syndrome)
Seek immediate medical attention if you develop a painful rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ibuprofen Major
Aspirin Moderate
ACE inhibitors Major
Diuretics Major
Lithium Moderate
Methotrexate Moderate
SSRIs Moderate
Corticosteroids Major
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, diclofenac)
  • Corticosteroids
  • ACE inhibitors and angiotensin receptor blockers
  • Diuretics

⚡ Moderate Interactions

  • Lithium
  • Methotrexate
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of stomach bleeding, ulcers, and liver damage. It can also worsen dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active liver disease or history of liver injury due to nimesulide","Active stomach ulcer or history of recurrent ulcers","Severe kidney disease","Severe heart failure","Allergy to nimesulide or other NSAIDs","Children under 12 years of age","Pregnancy, especially third trimester","Breastfeeding"]

⚠️ Warnings & Precautions

["Use the lowest effective dose for the shortest possible duration.","Take with food to reduce stomach upset.","Avoid alcohol completely.","Do not use with other NSAIDs.","Consult your doctor if you have liver, kidney, or heart disease.","Stop the medicine and seek medical help if you notice signs of liver problems (yellowing of eyes, dark urine).","Do not use for fever for more than 3 days or for pain for more than 5 days without medical advice."]

🤱 Lactation Safety

Not recommended during breastfeeding. Nimesulide may pass into breast milk and could harm the infant. Consult your doctor for alternative pain relief.

💊 Overdose Management

Overdose of this medicine can cause nausea, vomiting, stomach pain, drowsiness, and in severe cases, liver or kidney damage. If you suspect an overdose, contact your doctor or a poison control centre immediately. Treatment is supportive and may include activated charcoal if taken recently. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine only for the shortest duration and at the lowest dose that controls your symptoms, as advised by your doctor. Always take it with food or milk to reduce stomach irritation. Avoid alcohol completely while taking this medicine because it increases the risk of stomach bleeding and liver problems. Do not take other pain relievers or NSAIDs without consulting your doctor, as this can raise the risk of side effects. If you have liver or kidney disease, heart failure, or a history of stomach ulcers, tell your doctor before starting this medicine. Do not use this medicine during pregnancy, especially in the last trimester, or while breastfeeding unless your doctor specifically approves it. Keep all follow-up appointments and report any new symptoms such as yellowing of the skin, dark urine, or persistent stomach pain.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of stomach bleeding, kidney problems, and liver injury. Use with caution and at the lowest effective dose for the shortest duration. Regular monitoring of kidney and liver function is advised.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when trying to conceive. Consult your doctor for safer pain relief options.

🏥 Post-Surgery Considerations

This medicine may be used for short-term post-operative pain under medical supervision. However, it can increase bleeding risk, so inform your surgeon if you are taking it before surgery.

🦷 Dental Procedures

This medicine can be used for dental pain, but it may increase bleeding risk during dental procedures. Inform your dentist if you are taking it.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Engage in low-impact exercises like swimming or walking.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods like fruits, vegetables, and omega-3 rich fish in your diet.
🧘
Get adequate sleep to help your body recover.
🌞
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

While taking this medicine, you may feel dizzy or tired. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. Listen to your body and rest if you feel pain.

🥗 Diet Recommendations

Include omega-3 rich foods like flaxseeds and walnuts.
Reduce intake of processed and fried foods.
Stay well hydrated by drinking plenty of water.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually taken for a short duration, so work impact is minimal.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience any signs of liver problems (yellowing of eyes, dark urine), severe stomach pain, or allergic reactions. Do not stop abruptly if you are on a prescribed course without consulting your doctor. Usually, it is stopped after the prescribed short course.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to the risk of serious liver injury, kidney problems, and gastrointestinal bleeding. If prolonged use is necessary, regular monitoring of liver and kidney function is advised. Discuss with your doctor for safer alternatives for chronic pain.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help strengthen muscles and reduce pain in musculoskeletal conditions.

Evidence: Well-established
Paracetamol

A safer alternative for mild to moderate pain and fever.

Evidence: Well-established
Topical NSAIDs

Gels or creams can provide local pain relief with fewer systemic side effects.

Evidence: Established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If travelling across time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Do not leave it in a hot car.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with acute knee pain
Ravi developed severe knee pain after a fall. His doctor prescribed this medicine for 5 days. He took it with food twice daily and noticed significant pain relief within 2 hours. He avoided alcohol and completed the course without any stomach upset. He was advised not to take it longer than prescribed.
💡 Lesson: Taking this medicine with food and for a short duration improves tolerability and reduces risk.
👤 A 60-year-old woman with osteoarthritis
Mrs. Sharma had chronic knee osteoarthritis and was given this medicine for short-term pain relief. She initially felt better but developed nausea. Her doctor advised her to take it with meals and to stop after 5 days. She was switched to paracetamol for long-term pain management.
💡 Lesson: This medicine is not for long-term use. Alternative pain management should be discussed with the doctor.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: Is it safe for children?

A: It is not recommended for children under 12 years of age. Consult a pediatrician for alternatives.

Q: Can I take it with other painkillers?

A: Do not take it with other NSAIDs. Consult your doctor before combining with any other medicine.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for orange n kid tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is completely safe because it is commonly prescribed.
    Fact: This medicine carries a rare but serious risk of liver injury. It should only be used short-term and under medical supervision.
  • Myth: This medicine can be taken for any type of pain.
    Fact: It is only for specific types of pain and inflammation. It is not a first-choice medicine for fever or chronic pain.
  • Myth: It is safe to take this medicine with other painkillers.
    Fact: Combining with other NSAIDs increases the risk of stomach bleeding and kidney problems. Always consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Nimesulide 100 mg tablet

Brand Alternatives

  • Angip Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Nimesulide","class":"NSAID (sulphonanilide)","common_use":"Acute pain, inflammation","liver_risk":"High","stomach_risk":"Moderate"},{"medicine":"Paracetamol","class":"Analgesic/antipyretic","common_use":"Pain, fever","liver_risk":"High in overdose","stomach_risk":"Low"},{"medicine":"Ibuprofen","class":"NSAID","common_use":"Pain, inflammation, fever","liver_risk":"Low","stomach_risk":"Moderate to High"}]

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