Nutradol 50mg/325mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Slow, shallow, or difficult breathing
- Extreme sleepiness, confusion, or unresponsiveness
- Seizures or convulsions
- Agitation, hallucinations, rapid heart rate, fever, or muscle twitching (serotonin syndrome)
- Yellowing of skin or eyes, dark urine, or severe abdominal pain (liver injury)
- Severe rash, blistering, or peeling skin
- Swelling of face, lips, tongue, or throat, or difficulty swallowing
- Chest pain or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is nutradol 50mg/325mg tablet used for?
This medicine is a combination of tramadol (an opioid pain reliever) and paracetamol (a non-opioid pain reliever and fever reducer). It is used for short-term relief of moderate to severe pain when other painkillers are not enough. It works by blocking pain signals in the brain and spinal cord. It should only be taken as prescribed by a doctor.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nutradol 50mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ट्रामाडोल और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह उन स्थितियों में दी जाती है जब सामान्य दर्द निवारक दवाएं पर्याप्त राहत नहीं देतीं, जैसे सर्जरी के बाद का दर्द, चोट के कारण दर्द, या पुरानी दर्द की स्थिति का बढ़ना। यह दवा दर्द के संकेतों को मस्तिष्क और रीढ़ की हड्डी में रोककर काम करती है। इसे केवल डॉक्टर के निर्देशानुसार ही लें और निर्धारित अवधि से अधिक न लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, नींद आना, मतली, उल्टी, कब्ज, सिरदर्द और मुंह सूखना शामिल हैं। गंभीर दुष्प्रभावों में सांस लेने में कठिनाई, दौरे, सेरोटोनिन सिंड्रोम, गंभीर त्वचा प्रतिक्रियाएं और लीवर की क्षति शामिल हो सकती हैं। यदि आपको सांस लेने में तकलीफ, अत्यधिक नींद, भ्रम, या एलर्जी के लक्षण जैसे दाने, सूजन, या निगलने में कठिनाई हो, तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। निर्धारित खुराक या अवधि से अधिक न लें। इस दवा के साथ शराब का सेवन पूरी तरह से बंद कर दें, क्योंकि इससे लीवर की क्षति और गंभीर नींद आने का खतरा बढ़ सकता है। जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है, तब तक वाहन न चलाएं या भारी मशीनरी न चलाएं। यदि आपको दौरे, लीवर या गुर्दे की समस्या, सांस लेने में कठिनाई, या नशीली दवाओं के सेवन का इतिहास है, तो अपने डॉक्टर को बताएं। इस दवा के साथ पैरासिटामोल युक्त अन्य उत्पाद न लें।
💊 nutradol 50mg/325mg tablet Uses & Benefits
[{"condition":"Moderate to severe acute pain","description":"Used for short-term relief of pain that is not controlled by non-opioid analgesics alone, such as post-operative pain or injury-related pain.","evidence":"Well-established"},{"condition":"Chronic pain flare-ups","description":"May be prescribed for exacerbations of chronic pain conditions like osteoarthritis or low back pain when other treatments are insufficient.","evidence":"Moderate"},{"condition":"Pain associated with surgical procedures","description":"Often used in the immediate post-operative period for pain management under medical supervision.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes used off-label for certain types of nerve pain, though evidence is limited and other treatments are preferred.","evidence":"Limited"},{"condition":"Premature ejaculation","description":"Tramadol has been studied off-label for delaying ejaculation, but this is not a standard use and should only be under specialist care.","evidence":"Limited"}]
Primary treatment for: Moderate to severe acute pain
Also treats: Post-operative pain, Injury-related pain, Chronic pain flare-ups
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nutradol 50mg/325mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise specified on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two analgesics with complementary mechanisms. Tramadol is a centrally acting opioid analgesic that binds to mu-opioid receptors and also inhibits the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. Paracetamol acts primarily in the central nervous system to reduce pain and fever, though its exact mechanism is not fully established; it may involve inhibition of prostaglandin synthesis in the brain and modulation of pain perception.
Mechanism Steps
💡 How to Take nutradol 50mg/325mg tablet
Strength: Each tablet contains tramadol hydrochloride 50 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally every 4 to 6 hours as needed for pain, not to exceed the maximum daily dose. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Do not exceed the prescribed dose or duration. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 12 years of age. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of tramadol, especially respiratory depression and dizziness. Start with a lower dose and titrate slowly. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For creatinine clearance less than 30 mL/min, the dosing interval should be increased (e.g., every 12 hours) and the maximum daily dose reduced. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction and longer dosing intervals may be necessary. Avoid use in severe liver disease. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose should not exceed 8 tablets in 24 hours (equivalent to tramadol 400 mg and paracetamol 2600 mg). However, the exact maximum must be determined by a qualified clinician based on the patient's condition and other medications. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nutradol 50mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| Warfarin | Major | |
| Benzodiazepines | Major | |
| SSRIs | Major | |
| Carbamazepine | Moderate | |
| Fluoxetine | Moderate | |
| Rifampin | Moderate | |
| Anticholinergics | Moderate | |
| Metoclopramide | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- MAO inhibitors
- Warfarin
- CNS depressants (e.g., benzodiazepines, alcohol)
- SSRIs/SNRIs
- Carbamazepine
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, quinidine)
- CYP3A4 inducers (e.g., rifampin, St. John's wort)
- Anticholinergic drugs
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. It increases the risk of liver damage from paracetamol and can cause dangerous sedation and respiratory depression from tramadol.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to tramadol, paracetamol, or any component of the formulation","Severe respiratory depression or acute severe asthma","Uncontrolled epilepsy or seizure disorder","Severe liver impairment","Severe kidney impairment (creatinine clearance
⚠️ Warnings & Precautions
["Risk of respiratory depression, especially in elderly or debilitated patients.","May cause seizures, particularly in patients with a history of seizures or those taking other seizure-threshold-lowering drugs.","Risk of serotonin syndrome when used with SSRIs, SNRIs, or MAO inhibitors.","Potential for dependence and withdrawal with prolonged use.","Avoid alcohol and other CNS depressants.","Use with caution in patients with head injury, increased intracranial pressure, or brain tumors.","May impair mental and physical abilities required for driving or operating machinery.","Do not exceed the recommended dose of paracetamol to avoid liver damage.","Use with caution in patients with liver or kidney disease; dose adjustment may be needed.","Not recommended for chronic long-term use without regular medical review."]
🤱 Lactation Safety
Tramadol and paracetamol are excreted in breast milk. Limited data suggest tramadol may cause serious adverse reactions in breastfed infants, including excessive sleepiness and breathing difficulties. Consult your doctor before use; alternative analgesics may be preferred.
💊 Overdose Management
Overdose can cause severe respiratory depression, seizures, liver damage, and coma. Seek emergency medical help immediately. Treatment includes supportive care, airway management, and administration of naloxone for opioid toxicity. N-acetylcysteine is the antidote for paracetamol overdose and should be given as soon as possible. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor liver and kidney function closely.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid alcohol completely while taking this medicine, as it can increase the risk of liver damage and dangerous sedation. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have a history of seizures, liver or kidney problems, breathing difficulties, or substance abuse. Do not take other products containing paracetamol while on this medicine to avoid overdose. Keep out of reach of children. Store at room temperature away from moisture and heat. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of tramadol, especially respiratory depression, dizziness, and falls. Start with a lower dose and titrate slowly. Monitor renal and hepatic function regularly. Avoid concurrent use with other CNS depressants. Non-opioid analgesics may be preferred when possible.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Tramadol and paracetamol should be used during pregnancy only if clearly needed. Prolonged use near term may cause neonatal withdrawal or respiratory depression. Discuss alternative pain management options with your doctor.
🏥 Post-Surgery Considerations
This medicine may be prescribed for post-operative pain. Follow your surgeon's instructions carefully. Do not exceed the prescribed dose. Inform your surgeon if you have a history of substance abuse, liver or kidney disease, or breathing problems. Use the lowest effective dose for the shortest duration. Monitor for signs of respiratory depression, especially if you are also receiving other sedatives.
🦷 Dental Procedures
If you are undergoing dental procedures, inform your dentist that you are taking this medicine. It may interact with anesthetics or other medications used during dental work. Your dentist may need to adjust your treatment plan. Do not take additional painkillers without consulting your dentist or doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience drowsiness or dizziness. Avoid activities that require full alertness, such as driving or operating heavy machinery, until you know how the medicine affects you. Light exercise may be beneficial, but avoid strenuous activities that could worsen your pain or cause injury. Consult your doctor or physiotherapist for an appropriate exercise plan.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and impaired concentration, which may affect your ability to work, drive, or operate machinery. Avoid these activities until you know how the medicine affects you. Inform your employer if your job requires alertness. Take frequent breaks if you have a desk job, and use ergonomic aids to reduce pain.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your pain is no longer severe enough to require it, if you experience serious side effects, or if you have been taking it for longer than recommended. Do not stop suddenly after prolonged use without medical advice, as withdrawal symptoms may occur. Your doctor will guide you on tapering the dose safely.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, dependence, and withdrawal symptoms. It may also increase the risk of liver damage from paracetamol and other side effects. Regular monitoring of liver and kidney function, as well as pain control and signs of dependence, is recommended. This medicine should generally be used for short-term management only, and long-term use should be under strict medical supervision with periodic reassessment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve function.
Evidence: Well-establishedMay be used for mild to moderate pain instead of opioids.
Evidence: Well-establishedHelps manage chronic pain by changing thought patterns and coping skills.
Evidence: ModerateMay provide pain relief for some chronic pain conditions.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking. It is generally safe to receive vaccines while on this medicine, but consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue taking the medicine as prescribed, but adjust dosing times gradually to the new local schedule. Check local customs regulations regarding controlled substances, as tramadol may be restricted in some countries. Always declare it if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking the tablet.
A: The pain-relieving effect usually lasts about 4 to 6 hours, so dosing is typically every 4 to 6 hours as needed.
A: Do not take other products containing paracetamol or tramadol without consulting your doctor, as this can lead to overdose. Other painkillers may interact; always check with your doctor or pharmacist.
A: Use during pregnancy only if clearly needed and under medical supervision. Prolonged use near term may cause neonatal withdrawal or respiratory depression. Consult your doctor.
A: If you have been taking it for more than a few weeks, do not stop suddenly as it may cause withdrawal symptoms. Consult your doctor for a gradual taper.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is safe for long-term use.
Fact: This medicine is intended for short-term use only. Prolonged use can lead to dependence, tolerance, and other serious side effects. - Myth: It is okay to drink alcohol while taking this medicine.
Fact: Alcohol should be completely avoided as it increases the risk of liver damage and dangerous sedation. - Myth: This medicine can be taken for mild headaches.
Fact: This medicine is for moderate to severe pain and should not be used for mild pain or routine headaches. - Myth: If one tablet doesn't work, I can take two.
Fact: Never exceed the prescribed dose. Taking more can cause serious harm, including liver damage and respiratory depression.
🔄 Alternative Options
Generic Alternatives
- Tramadol 50 mg + Paracetamol 325 mg tablet (generic)
Brand Alternatives
- Not applicable; this is a generic combination.