Neurotrat Mp Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or slow, shallow breathing
- Sudden swelling of the face, lips, tongue, or throat
- Severe dizziness with fainting or falls
- New or worsening depression or suicidal thoughts
- Severe muscle pain, weakness, or dark urine
- Unusual bruising or bleeding
- Confusion, memory problems, or difficulty speaking
- Chest pain or severe shortness of breath
If experiencing severe symptoms, call emergency services immediately.
What is nuramed m capsule used for?
This medicine is a combination of methylcobalamin and pregabalin used to treat nerve pain such as diabetic neuropathy and postherpetic neuralgia. It works by reducing pain signals in the nervous system and supporting nerve health. It is taken by mouth, usually one to three times daily, and must be used only under medical supervision.
- Generic Name: Methylcobalamin (NA) + Pregabalin (NA)
- Manufacturer: Zydus Cadila
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nuramed m capsule के बारे में (Hindi Summary)
उपयोग: यह दवा मेथिलकोबालामिन और प्रेगाबालिन का संयोजन है, जिसका उपयोग नसों से जुड़े दर्द के इलाज के लिए किया जाता है। यह मधुमेह के कारण होने वाले न्यूरोपैथी दर्द, दाद के बाद बचे दर्द, और रीढ़ की हड्डी की चोट से जुड़े दर्द में मदद करती है। यह दवा नसों को आराम देने और दर्द के संकेतों को कम करने में सहायक है। इसे डॉक्टर की सलाह के बिना शुरू या बंद नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, नींद आना, मुँह सूखना, धुंधली दृष्टि, और हाथ-पैरों में सूजन शामिल हैं। कुछ लोगों में वजन बढ़ सकता है या एकाग्रता में कमी आ सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर साँस लेने में कठिनाई, गंभीर एलर्जी, या मन में आत्मघाती विचार आएँ तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। शराब न पिएँ, क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। अचानक दवा बंद न करें, क्योंकि इससे घबराहट, अनिद्रा, और सिरदर्द जैसी समस्याएँ हो सकती हैं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 nuramed m capsule Uses & Benefits
[{"condition":"Diabetic peripheral neuropathy","description":"This medicine is used to reduce burning, tingling, and shooting pain in the feet and hands caused by diabetes-related nerve damage.","evidence":"Well-established for pregabalin; methylcobalamin is commonly added for nerve support."},{"condition":"Postherpetic neuralgia","description":"This medicine can help relieve persistent nerve pain that remains after a shingles rash has healed.","evidence":"Well-established for pregabalin."},{"condition":"Neuropathic pain from spinal cord injury","description":"This medicine may be prescribed to reduce chronic nerve pain associated with spinal cord injury.","evidence":"Moderate evidence for pregabalin."},{"condition":"Fibromyalgia-related pain","description":"This medicine may be used in some patients to reduce widespread pain and improve sleep in fibromyalgia.","evidence":"Moderate evidence for pregabalin."},{"condition":"Partial-onset seizures","description":"Pregabalin in this medicine can be used as add-on therapy for certain types of seizures in adults.","evidence":"Well-established for pregabalin as adjunctive therapy."}]
Off-label uses: [{"condition":"Generalized anxiety disorder","description":"Pregabalin is sometimes prescribed off-label for short-term anxiety symptoms, but this is not a standard first-line use.","evidence":"Limited"},{"condition":"Chronic low back pain with nerve involvement","description":"This medicine may be tried off-label when back pain has a neuropathic component, but evidence is mixed.","evidence":"Limited"},{"condition":"Restless legs syndrome","description":"Pregabalin has been studied off-label for restless legs symptoms in some patients.","evidence":"Limited"}]
Primary treatment for: Neuropathic pain
Also treats: Diabetic peripheral neuropathy, Postherpetic neuralgia, Fibromyalgia, Spinal cord injury pain, Partial-onset seizures
📋 Drug Information
| Generic Name(s) | Methylcobalamin (NA) + Pregabalin (NA) |
| Brand Name | nuramed m capsule |
| Manufacturer | Zydus Cadila |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C in a dry place. Keep it in its original container, away from direct sunlight and moisture. Do not refrigerate unless the label specifically says so. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture, but always check the expiry date printed on the pack. Do not use this medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different but complementary actions. Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the influx of calcium into nerve terminals and decreases the release of excitatory neurotransmitters such as glutamate, substance P, and noradrenaline. As a result, pain signals traveling through the spinal cord and brain are dampened. Methylcobalamin is a coenzyme form of vitamin B12 that participates in methylation reactions needed for myelin synthesis and nerve cell maintenance. It supports the structural and functional integrity of peripheral nerves. Together, these actions help reduce neuropathic pain and support nerve health.
Mechanism Steps
💡 How to Take nuramed m capsule
Strength: This medicine is supplied as immediate-release tablets. The exact strength of methylcobalamin and pregabalin in this product is not specified in the available information. Check the label on your pack for the exact strength.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally one to three times daily, depending on the indication and the doctor's assessment. The dose of pregabalin in this combination is often started low and increased slowly to reduce side effects. The exact dose must be individualized by a qualified clinician based on the indication, age, weight, kidney function, liver function, and response to treatment. Do not change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults are more sensitive to the sedative and dizzying effects of pregabalin. The dose is usually started lower and increased more slowly. Kidney function should be checked before and during treatment, because reduced kidney function can cause the medicine to build up in the body. |
| Renal Impairment | Pregabalin is removed by the kidneys, so the dose must be reduced in people with kidney disease. The exact dose adjustment depends on the creatinine clearance and must be determined by a qualified clinician. Methylcobalamin does not usually need dose adjustment for kidney disease. |
| Hepatic Impairment | Pregabalin is not significantly metabolized by the liver, so dose adjustment is usually not needed for mild to moderate liver disease. However, people with severe liver disease should be monitored closely because they may be more sensitive to side effects. Methylcobalamin does not require dose adjustment for liver disease. |
| Maximum Daily Dose | The maximum daily dose of pregabalin in this combination is usually 600 mg per day, but most patients do not need this high a dose. The maximum daily dose of methylcobalamin in this combination is not clearly established from the available information. The exact maximum dose must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nuramed m capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Opioid pain medicines | Major | |
| Benzodiazepines | Major | |
| Alcohol | Major | |
| Antihistamines | Moderate | |
| Muscle relaxants | Moderate | |
| Blood pressure medicines | Moderate | |
| Antacids | Minor | |
| Oral contraceptives | Minor | |
| Diabetes medicines | Minor | |
| Diuretics | Moderate |
🚨 Major Interactions
- Opioid pain medicines
- Benzodiazepines and other sedatives
- Alcohol
⚡ Moderate Interactions
- Antihistamines
- Muscle relaxants
- Blood pressure medicines
🍷 Alcohol Interaction
Do not drink alcohol while taking this medicine. Alcohol increases the sedative effects of pregabalin and can cause excessive drowsiness, dizziness, falls, and serious breathing problems. The combination can also worsen liver health and make it harder to judge your level of alertness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to pregabalin, methylcobalamin, or any ingredient in this medicine","Severe kidney disease with very low creatinine clearance, unless dose is adjusted by a specialist","Use of opioid pain medicines or other strong sedatives without close medical supervision","Pregnancy, unless specifically approved by a specialist after weighing risks and benefits","Breastfeeding, unless a doctor advises otherwise"]
⚠️ Warnings & Precautions
["This medicine can cause dizziness and sleepiness. Do not drive or operate heavy machinery until you know how it affects you.","Do not stop this medicine suddenly, because withdrawal symptoms such as anxiety, insomnia, headache, nausea, and irritability can occur.","Tell your doctor if you have kidney disease, heart failure, or a history of depression or suicidal thoughts.","Avoid alcohol and other sedative medicines while taking this medicine.","This medicine may cause fluid retention and weight gain. Report rapid weight gain or swelling to your doctor.","Keep this medicine out of reach of children and store it in its original packaging."]
🤱 Lactation Safety
Pregabalin is present in breast milk, and its effects on a breastfed infant are not fully established. Breastfeeding while taking this medicine is not recommended unless a doctor decides that the benefit outweighs the risk. Methylcobalamin is generally considered compatible with breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause excessive sleepiness, confusion, dizziness, blurred vision, fast heartbeat, and difficulty breathing. If you suspect an overdose, seek emergency medical help immediately. Do not try to vomit unless a doctor tells you to. Treatment is supportive and may include monitoring of breathing, heart rate, and blood pressure. In severe cases, hospitalization and breathing support may be needed.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, and do not change the dose on your own. Because this medicine can cause dizziness and sleepiness, avoid driving, operating heavy machinery, or doing activities that need full alertness until you know how it affects you. Do not drink alcohol while taking this medicine, as alcohol can increase drowsiness and breathing problems. Tell your doctor about all other medicines you take, especially opioid painkillers, sleeping pills, anti-anxiety medicines, and antihistamines, because combining them with this medicine can be dangerous. Do not stop this medicine suddenly, because stopping too quickly can cause anxiety, insomnia, headache, nausea, or irritability. If you are pregnant, planning pregnancy, or breastfeeding, speak with your doctor before using this medicine. Keep this medicine out of reach of children, and store it in its original packaging at room temperature.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to experience dizziness, sleepiness, confusion, and falls while taking this medicine. The dose is usually started lower and increased more slowly. Kidney function should be checked before and during treatment, because reduced kidney function can cause the medicine to build up in the body. Regular monitoring of mood, weight, and balance is important.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, talk to your doctor before continuing this medicine. Pregabalin has been associated with an increased risk of birth defects in some studies. Your doctor may switch you to a different medicine or adjust the dose. Do not stop this medicine on your own if you are planning pregnancy; always seek medical advice first.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. Pregabalin can interact with anesthetic medicines and other sedatives, increasing the risk of drowsiness and breathing problems. Your doctor may advise you to stop or adjust the dose before surgery. Do not stop it on your own.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure. Pregabalin can increase the effects of sedatives and anesthetic medicines used during dental work. Your dentist may need to adjust the medicines used or take extra precautions. Do not stop this medicine on your own before a dental procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness, sleepiness, and unsteadiness. Avoid high-risk activities such as heavy weightlifting, contact sports, or exercises that require balance until you know how the medicine affects you. Gentle walking, stretching, and swimming are usually safe if your doctor agrees. Stop exercising and seek medical help if you feel faint, severely dizzy, or develop chest pain or severe shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and difficulty concentrating, which may affect your ability to drive, operate machinery, or perform tasks that require full alertness. It is best to avoid these activities until you know how the medicine affects you. Inform your employer if your job involves driving or heavy machinery. Most people can continue their usual desk work, but take regular breaks and avoid working late if you feel sleepy.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor may decide to stop it if your pain is well controlled, if you develop serious side effects, or if the medicine is no longer needed. Stopping suddenly can cause withdrawal symptoms such as anxiety, insomnia, headache, nausea, and irritability. If you need to stop, your doctor will usually reduce the dose gradually over several days to weeks.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to weight gain, fluid retention, and continued drowsiness in some people. Pregabalin can cause dependence, and stopping suddenly can lead to withdrawal symptoms. Regular monitoring of kidney function, weight, mood, and blood sugar is important. Some people may need periodic dose adjustments or a gradual taper if the medicine is to be stopped.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help improve strength, balance, and function in people with neuropathic pain.
Evidence: Well-establishedCan help people cope with chronic pain and reduce distress.
Evidence: ModerateMay provide additional pain relief in some people with nerve pain.
Evidence: LimitedSome people report benefit for chronic pain, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and routine vaccines. However, if you are scheduled for any vaccine, inform your healthcare provider about all medicines you are taking. If you have a fever or feel unwell, it is usually best to postpone vaccination until you recover.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you in case customs or security asks for it. Store the tablets in a cool, dry place and avoid leaving them in a hot car or in direct sunlight. If you are crossing time zones, ask your doctor how to adjust the timing of your doses. Do not pack this medicine in checked luggage; keep it in your hand baggage so you have access to it at all times.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some people notice improvement within a few days, but full benefit for nerve pain may take 1 to 2 weeks or longer. Your doctor may adjust the dose during this time.
A: No. Stopping suddenly can cause withdrawal symptoms such as anxiety, insomnia, headache, nausea, and irritability. Always talk to your doctor before stopping.
A: It can be used long-term under medical supervision, but regular follow-up is needed to check kidney function, weight, mood, and continued need for the medicine.
A: No. Alcohol increases the risk of drowsiness, dizziness, and serious breathing problems. Avoid alcohol completely while taking this medicine.
A: Yes, sleepiness and dizziness are common side effects, especially when starting treatment or increasing the dose. Avoid driving until you know how it affects you.
🤔 Common Patient Concerns
🔄 Substitutes for nuramed m capsule
View AllAlternative brands with exact same active ingredient:
-
nervimin a capsuleMoxy Laboratories Pvt Ltd ₹84.18 0.2% COSTLIER
-
preglobin m capsuleSymbiotic Drugs ₹84.38 0.5% COSTLIER
-
nerv 5 capsuleRPG Life Sciences Ltd ₹92.81 10.5% COSTLIER
-
neurotrat mp tabletZydus Cadila ₹151.78 80.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a simple painkiller for any type of pain.
Fact: This medicine is specifically for nerve-related pain and is not a general painkiller for headaches, muscle sprains, or fever. - Myth: This medicine can be stopped as soon as the pain improves.
Fact: Stopping suddenly can cause withdrawal symptoms. Always talk to your doctor before stopping. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol increases the risk of drowsiness, dizziness, and serious breathing problems. It should be avoided. - Myth: This medicine works immediately like a painkiller.
Fact: It may take several days to weeks to show full benefit for nerve pain.
🔄 Alternative Options
Generic Alternatives
- Methylcobalamin and pregabalin combination
Brand Alternatives
- Neurotrat MP Tablet