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Nura Ac 200mg/20mg Capsule Sr: Complete Medicine Guide

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Information coming soon
🏭 Generic 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 28, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 28, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual fatigue or weakness

If experiencing severe symptoms, call emergency services immediately.

What is nura ac 200mg/20mg capsule sr used for?

This medicine is a combination of aceclofenac (an NSAID) and rabeprazole (a proton pump inhibitor) used to treat pain and inflammation in conditions like arthritis while protecting the stomach from ulcers. It is taken once daily with food.

  • Generic Name: Information coming soon
  • Manufacturer: Multiple manufacturers
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nura ac 200mg/20mg capsule sr के बारे में (Hindi Summary)

उपयोग: यह दवा एसिफेनाक और रेबेप्राजोल का संयोजन है, जिसका उपयोग गठिया, जोड़ों के दर्द, सूजन और अन्य सूजन संबंधी स्थितियों के इलाज के लिए किया जाता है। यह पेट की परत की रक्षा करने में मदद करती है और दर्द व सूजन को कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, सिरदर्द, पेट दर्द, अपच और गैस शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत विषाक्तता और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, उल्टी में खून, या गंभीर पेट दर्द हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की जलन कम हो। कैप्सूल को चबाएं या तोड़ें नहीं। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। गुर्दे और यकृत की कार्यप्रणाली की नियमित जांच कराएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 nura ac 200mg/20mg capsule sr Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness associated with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate pain and inflammation in the spine and sacroiliac joints.","evidence":"Well-established"},{"condition":"Acute gouty arthritis","description":"May be used to relieve acute pain and inflammation in gout attacks.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Can be used for relief of menstrual cramps and associated pain.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label for preventing migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Postoperative pain","description":"May be used off-label for short-term management of postoperative pain, but not routinely recommended.","evidence":"Limited"}]

Primary treatment for: Osteoarthritis

Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute gouty arthritis, Dysmenorrhea

📋 Drug Information

Generic Name(s)Information coming soon
Brand Namenura ac 200mg/20mg capsule sr
ManufacturerMultiple manufacturers
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Swallow the capsule whole; do not crush or chew it.
3
Avoid alcohol while taking this medicine to prevent stomach bleeding.
4
Do not take other NSAIDs or pain relievers without consulting your doctor.
5
Monitor for signs of gastrointestinal bleeding such as black stools or vomiting blood.
6
Regularly check kidney and liver function during long-term use.
7
Inform your doctor if you have a history of heart, kidney, or liver disease.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Acute headache
Not typically used for acute headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAceclofenac is rapidly absorbed after oral administration, with peak plasma concentrations occurring approximately 1.25 to 3 hours after intake. Rabeprazole is also rapidly absorbed, with peak plasma levels reached within 2 to 5 hours. The sustained-release formulation may alter the absorption rate, providing a more gradual release.
DistributionAceclofenac is highly protein-bound (greater than 99%) and distributes into synovial fluid, which is beneficial for joint conditions. Rabeprazole is approximately 96% protein-bound and distributes into gastric parietal cells.
Protein BindingAceclofenac: >99% bound to plasma proteins, primarily albumin. Rabeprazole: approximately 96% bound to plasma proteins.
MetabolismAceclofenac is metabolized in the liver primarily by cytochrome P450 2C9 to inactive metabolites. Rabeprazole is metabolized in the liver by cytochrome P450 2C19 and 3A4 to inactive metabolites.
Half-LifeAceclofenac: approximately 4 hours. Rabeprazole: approximately 1 to 2 hours.
ExcretionAceclofenac metabolites are excreted mainly in urine (about 70-80%) and feces (about 20%). Rabeprazole metabolites are excreted primarily in urine (about 90%) and feces (about 10%).
BioavailabilityAceclofenac: approximately 100% due to rapid absorption. Rabeprazole: approximately 52% due to first-pass metabolism.
Onset of ActionAceclofenac: pain relief may begin within 30 to 60 minutes. Rabeprazole: acid suppression begins within 1 hour but maximal effect may take several days.
Peak Plasma TimeAceclofenac: 1.25 to 3 hours. Rabeprazole: 2 to 5 hours.
Duration of ActionAceclofenac: 12 to 24 hours. Rabeprazole: acid suppression lasts up to 24 hours.

How It Works

This medicine combines aceclofenac, a nonsteroidal anti-inflammatory drug (NSAID), and rabeprazole, a proton pump inhibitor (PPI). Aceclofenac works by inhibiting the cyclooxygenase (COX) enzymes, particularly COX-2, which are involved in the production of prostaglandins that mediate pain, inflammation, and fever. By blocking these enzymes, aceclofenac reduces pain and swelling. Rabeprazole suppresses gastric acid secretion by irreversibly inhibiting the H+/K+-ATPase (proton pump) in the parietal cells of the stomach. This reduces the risk of aceclofenac-induced gastrointestinal irritation and ulceration. The sustained-release formulation allows for gradual release of both drugs, potentially providing prolonged effect and improved tolerability.

Mechanism Steps

1
Aceclofenac absorption: Aceclofenac is absorbed from the gastrointestinal tract after oral administration.
2
COX enzyme inhibition: Aceclofenac inhibits cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby decreasing pain and inflammation.
3
Rabeprazole absorption: Rabeprazole is absorbed and accumulates in the acidic environment of the stomach's parietal cells.
4
Proton pump inhibition: Rabeprazole irreversibly inhibits the H+/K+-ATPase pump, blocking the final step of gastric acid secretion.
5
Gastroprotection: Reduced acid secretion helps prevent aceclofenac-induced gastric irritation and ulcer formation.

💡 How to Take nura ac 200mg/20mg capsule sr

Strength: Sustained-release capsule containing aceclofenac 200 mg and rabeprazole 20 mg.

1Swallow the capsule whole with a glass of water.
2Take it with food to reduce stomach upset.
3Do not crush, chew, or break the capsule.
4Take at the same time each day.
5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one capsule (aceclofenac 200 mg and rabeprazole 20 mg) taken orally once daily with food, or as directed by your doctor. The dose may be adjusted based on your condition and response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Use with caution and monitor kidney and liver function. Dose adjustment may be necessary.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose reduction may be required. Consult your doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose reduction may be required. Consult your doctor for individualized dosing.
Maximum Daily DoseOne capsule per day. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nura ac 200mg/20mg capsule sr

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. If persistent, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if severe or persistent.
Headache (Common (5-10%))
Usually resolves. Consult doctor if severe.
Abdominal pain (Common (5-10%))
Take with food. If severe, seek medical advice.
Flatulence (Common (5-10%))
Usually harmless. Consult doctor if bothersome.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Peptic ulcer (Rare (<0.1%))
Report persistent stomach pain or indigestion to your doctor immediately.
Kidney impairment (Rare (<0.1%))
Regular monitoring may be needed. Report decreased urine output or swelling.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Anaphylaxis
Call emergency services immediately.
Stevens-Johnson syndrome
Seek immediate medical attention if you develop rash, blisters, or peeling skin.
Aplastic anemia
Report unusual fatigue, infections, or bleeding.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Other NSAIDs Major
Corticosteroids Major
ACE inhibitors Moderate
Diuretics Moderate
Ketoconazole Moderate
Antacids Minor
Sucralfate Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Other NSAIDs
  • Corticosteroids

⚡ Moderate Interactions

  • Antihypertensives (e.g., ACE inhibitors, ARBs)
  • Diuretics
  • Ketoconazole

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the risk of stomach bleeding and ulcers, and may worsen side effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to aceclofenac, rabeprazole, or any component of the formulation","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney impairment","Severe liver impairment","Pregnancy (third trimester)","Breastfeeding"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Do not crush, chew, or break the sustained-release capsule.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of side effects.","Monitor kidney and liver function during long-term use.","May increase risk of cardiovascular events; use with caution in patients with heart disease.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use for more than the recommended duration without medical advice."]

🤱 Lactation Safety

Not established from the available information. Consult a doctor before use while breastfeeding.

💊 Overdose Management

Overdose may cause severe stomach pain, vomiting, drowsiness, and kidney problems. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the sustained-release capsule; swallow it whole with a glass of water. It is best taken with food to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Regular monitoring of kidney function, liver function, and blood counts may be needed during long-term therapy. Do not use this medicine for more than the recommended duration unless advised by your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning pregnancy. This medicine may not be safe during pregnancy, especially in the third trimester.

🏥 Post-Surgery Considerations

Use with caution after surgery due to increased risk of bleeding and kidney problems. Consult your surgeon before taking this medicine.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase bleeding risk during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Avoid high-impact activities that may worsen joint pain. Consult a physiotherapist for safe exercises. If you experience dizziness, avoid activities requiring balance.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Eat plenty of fruits and vegetables

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, seek medical advice immediately. Your doctor may adjust the dose or switch to another medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, and liver toxicity. Regular monitoring of kidney and liver function, as well as blood counts, is recommended. Cardiovascular risk may also be elevated. Use the lowest effective dose for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Weight management

Reduces stress on joints and improves symptoms.

Evidence: Well-established
Acupuncture

May help with pain relief in some patients.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with knee osteoarthritis
He was prescribed this medicine for chronic knee pain. After taking it with food daily for two weeks, he noticed significant reduction in pain and stiffness. He was advised to monitor his kidney function regularly.
💡 Lesson: Consistent use with food improves tolerability and effectiveness.
👤 A 40-year-old woman with rheumatoid arthritis
She started this medicine along with her regular arthritis treatment. She experienced mild nausea initially, which subsided after taking it with meals. Her joint swelling decreased over a month.
💡 Lesson: Taking the medicine with food can minimize gastrointestinal side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief may begin within 30 to 60 minutes, but full anti-inflammatory effects may take several days to weeks.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce stomach upset.

Q: Is it safe for long-term use?

A: Long-term use requires regular monitoring of kidney and liver function. Consult your doctor.

Q: What if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any type of pain.
    Fact: It is specifically for inflammatory pain and should not be used for all pain types without medical advice.
  • Myth: It is safe to take without food.
    Fact: Taking it with food reduces the risk of stomach upset and ulcers.
  • Myth: It can be taken long-term without monitoring.
    Fact: Long-term use requires regular monitoring of kidney and liver function.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac 200 mg + Rabeprazole 20 mg sustained-release capsules

📊 Comparison with Similar Medicines

[{"medicine":"Aceclofenac + Rabeprazole","composition":"Aceclofenac 200 mg + Rabeprazole 20 mg","dosage_form":"Sustained-release capsule","frequency":"Once daily"},{"medicine":"Aceclofenac + Pantoprazole","composition":"Aceclofenac 200 mg + Pantoprazole 20 mg","dosage_form":"Tablet","frequency":"Once daily"},{"medicine":"Diclofenac + Rabeprazole","composition":"Diclofenac 100 mg + Rabeprazole 20 mg","dosage_form":"Capsule","frequency":"Once daily"}]

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