Dexibuprofen 200 Mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual weight gain or swelling
- Severe skin rash or blistering
If experiencing severe symptoms, call emergency services immediately.
What is nuprin 200 tablet used for?
Dexibuprofen 200 mg tablet is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever in conditions like arthritis, menstrual cramps, and musculoskeletal injuries. It works by blocking COX enzymes and reducing prostaglandins. Take it with food to avoid stomach upset, and do not exceed 600 mg per day.
- Generic Name: Dexibuprofen (200mg)
- Manufacturer: Strides shasun Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nuprin 200 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डेक्सिबुप्रोफेन (200 मिलीग्राम) टैबलेट है, जो एक नॉनस्टेरॉइडल एंटी-इंफ्लेमेटरी ड्रग (NSAID) है। इसका उपयोग दर्द, सूजन और बुखार को कम करने के लिए किया जाता है, जैसे कि गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), मासिक धर्म में होने वाले दर्द, मांसपेशियों में चोट, और दांत दर्द में। यह शरीर में प्रोस्टाग्लैंडिन नामक रसायनों को कम करके काम करती है, जो दर्द और सूजन का कारण बनते हैं। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इस दवा को डॉक्टर की सलाह के बिना लंबे समय तक नहीं लेना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सीने में जलन, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, लीवर की क्षति, गंभीर एलर्जी प्रतिक्रियाएं, और दिल का दौरा या स्ट्रोक का खतरा बढ़ना शामिल है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, पेशाब कम आना, चेहरे या गले में सूजन, या सीने में दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अनुशंसित खुराक से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब न लें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें। यदि आपको पेट के अल्सर, गुर्दे या लीवर की बीमारी, उच्च रक्तचाप, या हृदय की समस्या है, तो अपने डॉक्टर को बताएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो इस दवा का उपयोग करने से पहले अपने डॉक्टर से परामर्श करें। बच्चों की पहुंच से दूर रखें।
💊 nuprin 200 tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Mild to moderate acute pain","description":"Used for short-term relief of pain from musculoskeletal injuries, dental pain, or post-operative pain.","evidence":"Well-established"},{"condition":"Primary dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Alzheimer's disease","description":"Some studies suggest NSAIDs like dexibuprofen may reduce risk, but evidence is inconclusive and not recommended for this use.","evidence":"Insufficient"}]
Primary treatment for: Pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Dysmenorrhea, Acute musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Dexibuprofen (200mg) |
| Brand Name | nuprin 200 tablet |
| Manufacturer | Strides shasun Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Do not refrigerate unless specified. Keep in the original container, tightly closed. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Dexibuprofen is a nonsteroidal anti-inflammatory drug that works by reversibly inhibiting the cyclooxygenase (COX) enzymes, primarily COX-2, which are responsible for converting arachidonic acid into prostaglandins. Prostaglandins are mediators of pain, inflammation, and fever. By blocking their production, dexibuprofen reduces pain, swelling, and fever. It also inhibits COX-1 to a lesser extent, which can lead to gastrointestinal side effects.
Mechanism Steps
💡 How to Take nuprin 200 tablet
Strength: Dexibuprofen 200 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 200 mg taken orally up to three times daily as needed for pain and inflammation. The maximum recommended daily dose is 600 mg. For osteoarthritis and rheumatoid arthritis, the dose may be 200 mg two to three times daily. For acute pain, 200 mg every 4 to 6 hours as needed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. Take with food or milk to reduce stomach upset. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | In patients with mild renal impairment (creatinine clearance 60-89 mL/min), no dose adjustment is usually necessary. In moderate renal impairment (creatinine clearance 30-59 mL/min), use with caution and consider dose reduction. In severe renal impairment (creatinine clearance <30 mL/min), use is contraindicated. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no dose adjustment is usually necessary. In severe hepatic impairment, use is contraindicated. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | 600 mg per day. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nuprin 200 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Aspirin
- Other NSAIDs
- Corticosteroids
- Anticoagulants (e.g., heparin, clopidogrel)
- Lithium
- Methotrexate
⚡ Moderate Interactions
- ACE inhibitors
- Angiotensin II receptor blockers (ARBs)
- Diuretics
- Beta-blockers
- Cyclosporine
- Tacrolimus
- SSRIs
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding, ulceration, and liver damage. It may also enhance the central nervous system side effects such as dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to dexibuprofen, ibuprofen, or other NSAIDs","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Active peptic ulcer disease or history of recurrent peptic ulcers","Severe heart failure","Severe liver impairment","Severe kidney impairment","Third trimester of pregnancy","Coronary artery bypass graft (CABG) surgery perioperative period"]
⚠️ Warnings & Precautions
["Cardiovascular risk: NSAIDs may increase the risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke. Use the lowest effective dose for the shortest duration.","Gastrointestinal risk: NSAIDs can cause gastrointestinal bleeding, ulceration, and perforation, which can be fatal. Elderly patients are at higher risk.","Renal effects: NSAIDs can cause acute kidney injury, especially in patients with dehydration, heart failure, or pre-existing kidney disease.","Hepatic effects: NSAIDs can cause liver injury. Monitor liver function if prolonged use.","Allergic reactions: Serious allergic reactions, including anaphylaxis, can occur. Discontinue and seek immediate medical help if suspected.","Skin reactions: Serious skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported. Discontinue at first sign of rash.","Use in pregnancy: Avoid during third trimester. Use with caution in first and second trimesters.","Use in elderly: Increased risk of GI bleeding and kidney problems. Use with caution.","Use in children: Safety and efficacy not established in children under 18 years.","Alcohol: Avoid alcohol as it increases the risk of GI bleeding."]
🤱 Lactation Safety
Dexibuprofen is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor before use. Monitor the infant for any signs of adverse effects.
💊 Overdose Management
Overdose of dexibuprofen may cause symptoms such as nausea, vomiting, abdominal pain, headache, dizziness, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, liver damage, and coma. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be administered if the patient presents within 1-2 hours of ingestion. Monitor vital signs, kidney and liver function, and provide supportive care. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, high blood pressure, or heart problems. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events when taking NSAIDs. Use the lowest effective dose for the shortest duration. Monitor kidney function, blood pressure, and signs of bleeding. Avoid concomitant use with anticoagulants or corticosteroids if possible.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs may interfere with ovulation and implantation. Avoid use during the third trimester due to risk of premature closure of the ductus arteriosus. Use effective contraception if you are taking this medicine and do not wish to become pregnant.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used for pain relief, but it can increase the risk of bleeding and interfere with bone healing. Consult your surgeon before taking it. It is often avoided in the perioperative period of certain surgeries, such as coronary artery bypass graft (CABG).
🦷 Dental Procedures
If you are scheduled for dental work, inform your dentist that you are taking this medicine. It may increase bleeding during procedures. Your dentist may advise you to stop taking it temporarily before surgery. It can also be used for dental pain relief, but follow your dentist's instructions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. If you have joint pain, consult a physiotherapist for safe exercises. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or blurred vision in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. If your work involves physical labor, take breaks and avoid overexertion. Inform your employer if you need accommodations.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach bleeding, kidney problems, allergic reactions, or if your pain does not improve after 7-10 days of use. Do not stop abruptly if you are taking it for a chronic condition without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney problems, liver damage, and cardiovascular events such as heart attack and stroke. Regular monitoring of kidney and liver function, blood pressure, and blood counts may be required. Use the lowest effective dose for the shortest duration possible. Consult your doctor if you need to take this medicine for more than 10 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help relieve chronic pain, but evidence is mixed.
Evidence: ModerateMay provide localized pain relief with fewer systemic side effects.
Evidence: Well-establishedCan help reduce pain and inflammation in muscles and joints.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider that you are taking this medicine. It is generally safe to continue, but your doctor may advise temporary discontinuation if you have an acute illness with fever.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription in case you need to show it at customs. Store at room temperature and avoid extreme heat or cold. If crossing time zones, adjust dosing times gradually; for short-term use, take as needed for pain. Do not pack in checked luggage; keep it in your carry-on. Check local regulations regarding bringing prescription medicines into your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 minutes to 1 hour after taking it by mouth. The anti-inflammatory effect may take a few days of regular use to become noticeable.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset and bleeding. Taking it on an empty stomach may increase these risks.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: This medicine can interact with several other drugs, including blood thinners, aspirin, and blood pressure medicines. Always inform your doctor about all medications you are taking.
A: Avoid this medicine during the third trimester of pregnancy. Consult your doctor before use if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for nuprin 200 tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Dexibuprofen is completely safe and has no side effects.
Fact: Like all NSAIDs, dexibuprofen can cause side effects, including stomach bleeding, kidney problems, and increased cardiovascular risk, especially with long-term use. - Myth: You can take dexibuprofen on an empty stomach without any issues.
Fact: Taking dexibuprofen on an empty stomach increases the risk of stomach upset and bleeding. It should be taken with food or milk. - Myth: Dexibuprofen is safe to take during pregnancy.
Fact: Dexibuprofen should be avoided during the third trimester of pregnancy due to risk of complications. Consult your doctor before use. - Myth: Dexibuprofen can be taken with other pain relievers without any risk.
Fact: Combining dexibuprofen with other NSAIDs or aspirin can increase the risk of side effects. Always consult your doctor before combining.
🔄 Alternative Options
Generic Alternatives
- Dexibuprofen 200 mg tablet
Brand Alternatives
- Nuprin 200 tablet