Numinac-pt Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit, or black, tarry stools.
- Severe abdominal pain or persistent indigestion.
- Chest pain, shortness of breath, or difficulty breathing.
- Severe headache with visual changes or confusion.
- Sudden swelling of face, lips, tongue, or throat.
- Yellowing of skin or eyes, or dark urine.
- Decreased urine output or swelling in legs.
- Unusual bleeding or bruising.
- Severe skin rash with blisters or peeling.
- High fever with sore throat or unusual tiredness.
If experiencing severe symptoms, call emergency services immediately.
What is numinac-pt tablet used for?
This medicine is a combination of aceclofenac and paracetamol used to relieve pain and inflammation in conditions like arthritis, musculoskeletal injuries, and dental pain. It works by reducing prostaglandins that cause pain and swelling. Take it as prescribed, usually twice daily with food, and avoid alcohol.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 numinac-pt tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिफेनाक और पैरासिटामोल का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह गठिया, मांसपेशियों की चोट, दांत दर्द, और मासिक धर्म के दर्द में राहत देती है। यह शरीर में प्रोस्टाग्लैंडिन नामक रसायन को कम करके काम करती है, जो दर्द और सूजन का कारण बनता है। इसे डॉक्टर के निर्देशानुसार, आमतौर पर दिन में दो बार भोजन के साथ लेना चाहिए। इस दवा को शराब के साथ न लें, क्योंकि इससे लीवर और पेट की समस्याएं हो सकती हैं। गर्भवती महिलाओं और स्तनपान कराने वाली माताओं को डॉक्टर से सलाह लेने के बाद ही इसका सेवन करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें पेट या आंतों में रक्तस्राव, अल्सर, गुर्दे की समस्या, लीवर की क्षति, गंभीर एलर्जी प्रतिक्रिया, और हृदय संबंधी घटनाएं शामिल हो सकती हैं। यदि आपको कोई गंभीर या लगातार लक्षण महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट की जलन कम हो। इस दवा के साथ शराब का सेवन न करें, क्योंकि इससे लीवर की क्षति और पेट में रक्तस्राव का खतरा बढ़ सकता है। अन्य एनएसएआईडी या पैरासिटामोल युक्त दवाओं को एक साथ न लें। यदि आपको पेट के अल्सर, गुर्दे या लीवर की बीमारी, हृदय की समस्या, या अस्थमा है, तो अपने डॉक्टर को बताएं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो इस दवा का उपयोग करने से पहले डॉक्टर से सलाह लें। यदि आपको चक्कर या नींद आती है, तो वाहन चलाने या मशीनरी चलाने से बचें। बच्चों की पहुंच से दूर रखें।
💊 numinac-pt tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate pain and inflammation in the spine and sacroiliac joints.","evidence":"Well-established"},{"condition":"Acute musculoskeletal injuries","description":"Provides short-term relief from pain and inflammation due to sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of mild to moderate post-operative pain.","evidence":"Moderate"},{"condition":"Dental pain","description":"Effective for relieving dental pain such as toothache and post-extraction pain.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Helps relieve menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Fever","description":"Paracetamol component may reduce fever, but the combination is not primarily indicated for fever alone.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation associated with musculoskeletal conditions
Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute musculoskeletal injuries, Post-operative pain, Dental pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | numinac-pt tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac, an NSAID, inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system, where it inhibits prostaglandin synthesis and may also modulate pain perception through other pathways. The combination provides enhanced analgesic and anti-inflammatory effects compared to either agent alone.
Mechanism Steps
💡 How to Take numinac-pt tablet
Strength: This medicine is available as an immediate-release tablet containing aceclofenac 100 mg and paracetamol 325 mg. The strength may vary by manufacturer. Always check the label for the exact composition.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally two times a day, preferably with food or milk to reduce stomach upset. The exact dose and duration of treatment must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to treatment. Do not exceed the recommended dose. For acute conditions, the duration is usually limited to 7-10 days unless otherwise directed by your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration possible. Regular monitoring of renal and hepatic function is recommended. Consult your doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary in patients with mild to moderate renal impairment. This medicine is contraindicated in severe renal impairment (creatinine clearance <30 mL/min). Consult your doctor for dose adjustment based on renal function. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction and monitoring of liver function tests are recommended. This medicine is contraindicated in severe hepatic impairment. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum daily dose of this medicine is generally two tablets per day, providing 200 mg aceclofenac and 650 mg paracetamol per tablet, totaling 400 mg aceclofenac and 1300 mg paracetamol per day. However, the exact maximum dose may vary based on the specific product and clinical judgment. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of numinac-pt tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| SSRIs | Moderate | |
| Oral hypoglycemics | Moderate | |
| Phenytoin | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
- ACE inhibitors and angiotensin receptor blockers
- Diuretics
⚡ Moderate Interactions
- Antihypertensives (e.g., beta-blockers, calcium channel blockers)
- SSRIs
- Oral hypoglycemics
- Phenytoin
- Probenecid
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and may potentiate liver damage, especially due to the paracetamol component. It can also increase drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to aceclofenac, paracetamol, or any other NSAIDs.","Active peptic ulcer or history of recurrent peptic ulcer.","Severe heart failure.","Severe kidney impairment (e.g., creatinine clearance
⚠️ Warnings & Precautions
["Take with food or milk to reduce gastrointestinal irritation.","Avoid alcohol consumption while taking this medicine.","Do not exceed the recommended dose or duration of treatment.","Use with caution in elderly patients due to increased risk of side effects.","Use with caution in patients with a history of gastrointestinal bleeding or ulcers.","Monitor liver and kidney function during prolonged use.","Avoid concurrent use with other NSAIDs or paracetamol-containing products.","Consult your doctor if you have asthma, especially if you have had reactions to NSAIDs.","Do not drive or operate machinery if you experience dizziness or drowsiness.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Aceclofenac and paracetamol are excreted in breast milk in small amounts. Paracetamol is generally considered safe during breastfeeding. Aceclofenac should be used with caution as its effects on the nursing infant are not well established. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to the paracetamol component, and gastrointestinal bleeding, kidney failure, and central nervous system effects due to aceclofenac. Symptoms of overdose may include nausea, vomiting, abdominal pain, drowsiness, confusion, and jaundice. If you suspect an overdose, seek emergency medical attention immediately. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and gastrointestinal bleeding. Do not take other NSAIDs or paracetamol-containing products simultaneously to avoid overdose. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Regular monitoring of renal and hepatic function, blood pressure, and complete blood count is recommended. Avoid concurrent use with other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like aceclofenac may interfere with ovulation and are generally avoided during pregnancy, especially in the third trimester. Paracetamol is considered safer but should be used at the lowest effective dose for the shortest duration.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain management, but it should be prescribed by your surgeon. It can increase the risk of bleeding, so inform your surgeon if you are taking it before surgery. It may also delay bone healing in some cases. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
If you are undergoing dental procedures, inform your dentist that you are taking this medicine. It may increase the risk of bleeding during and after the procedure. Your dentist may advise you to stop it temporarily or adjust the dose. It can also be used for dental pain relief, but only under medical supervision.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require high alertness until you know how the medicine affects you. If you have joint pain, consult a physiotherapist for safe exercises. Do not overexert yourself, as this may worsen inflammation.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. If your work involves physical labor, take precautions to avoid injury. Inform your employer if you need accommodations.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or signs of liver or kidney problems. Do not stop abruptly if you have been on long-term therapy without consulting your doctor, as this may cause rebound pain. Follow your doctor's instructions regarding the duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of liver and kidney function, blood pressure, and complete blood count is recommended. It is advisable to use the lowest effective dose for the shortest duration possible. Consult your doctor if you need to use it for more than 10-14 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help reduce pain in some individuals.
Evidence: ModerateCreams or gels containing NSAIDs can provide localized pain relief with fewer systemic side effects.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and inflammation.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking. It is generally safe to continue this medicine unless advised otherwise.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking it as prescribed, but adjust timing gradually to avoid missed doses. Check customs regulations for carrying prescription medicines. Always keep it in your carry-on luggage. If you have any medical condition or are taking other medications, carry a list of your medicines and inform your travel companions.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it. However, the full anti-inflammatory effect may take a few days of regular use.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset and gastrointestinal irritation.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol should be avoided while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding.
A: Consult your doctor before using this medicine if you are pregnant or planning to become pregnant. NSAIDs like aceclofenac are generally avoided in the third trimester.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is completely safe and can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. It can cause serious side effects, especially with prolonged use. - Myth: Taking this medicine with alcohol is fine.
Fact: Alcohol increases the risk of liver damage and gastrointestinal bleeding. It should be avoided while taking this medicine. - Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food or milk to reduce stomach upset and the risk of gastrointestinal irritation. - Myth: If one tablet works, two tablets will work faster.
Fact: Taking more than the prescribed dose can lead to serious side effects such as liver damage and gastrointestinal bleeding. Always follow the prescribed dose. - Myth: This medicine is safe to take during pregnancy.
Fact: NSAIDs like aceclofenac are generally avoided during pregnancy, especially in the third trimester. Consult your doctor before use.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac + Paracetamol combination tablets from various manufacturers.
Brand Alternatives
- Numinac-PT Tablet