Acloveer 800 Tablet (Acyclovir 800 mg): Complete Medicine Guide

• [{"condition":"Herpes zoster (shingles)","description":"This medicine is used to treat shingles, a painful blistering rash caused by reactivation of varicella-zoster virus.
• Starting treatment within 72 hours of rash onset helps reduce pain and speed healing.","evidence":"Well-established"},{"condition":"Genital herpes","description":"This medicine is used to treat initial and recurrent episodes of genital herpes caused by herpes simplex virus.
• It reduces viral shedding, shortens outbreak duration, and relieves symptoms.","evidence":"Well-established"},{"condition":"Herpes labialis (cold sores)","description":"Systemic acyclovir can be used for severe or recurrent cold sores, especially in immunocompromised patients or when topical therapy is not enough.","evidence":"Well-established"},{"condition":"Chickenpox (varicella)","description":"This medicine may be prescribed for chickenpox in older children, adolescents, and adults who are at higher risk of complications, when started within 24 hours of rash onset.","evidence":"Well-established"},{"condition":"Herpes simplex skin and mucous membrane infections","description":"This medicine is used for herpes simplex infections of the skin and mucous membranes, including in immunocompromised patients.","evidence":"Well-established"},{"condition":"Herpes simplex encephalitis (as part of treatment)","description":"Intravenous acyclovir is the standard treatment for herpes simplex encephalitis.
• The oral 800 mg tablet is not used for this serious condition.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Bell's palsy","description":"Some clinicians add acyclovir to corticosteroid therapy for Bell's palsy based on the theory that herpes simplex virus may trigger the condition. Evidence is mixed and this is not a standard approved use.","evidence":"Limited"},{"condition":"Eczema herpeticum","description":"This medicine may be used in some patients with eczema herpeticum, a serious herpes simplex skin infection, but intravenous therapy is often preferred in severe cases.","evidence":"Limited"},{"condition":"Prevention of herpes simplex reactivation after facial procedures","description":"Some dentists and dermatologists prescribe acyclovir before or after certain facial procedures in patients with a history of cold sores. Evidence is limited.","evidence":"Limited"}]

Primary treatment for: Herpes zoster (shingles)

Also treats: Genital herpes, Herpes labialis (cold sores), Chickenpox in older children and adults, Herpes simplex skin infections, Herpes simplex mucous membrane infections

Generic Name(s)	Acyclovir (800mg)
Brand Name	nuclovir 800mg tablet
Manufacturer	Nukind Healthcare Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Antiviral (Non-HIV) drugs
Route of Administration	Oral
Storage	Store this medicine at room temperature, between 15°C and 30°C, in a dry place. Keep it in the original container with the lid tightly closed. Protect it from direct sunlight and moisture. Do not store it in the bathroom. Keep it out of reach of children and pets.
Shelf Life	The shelf life of this medicine is typically 24 to 36 months from the date of manufacture, depending on the manufacturer and pack. Always check the expiry date printed on the pack and do not use the medicine after that date.
WHO Guideline	The World Health Organization and other international guidelines recognize acyclovir as an effective antiviral for herpes simplex virus and varicella-zoster virus infections. Specific recommendations depend on the condition and patient group. Always follow the advice of your local clinician and national guidelines.
ICMR Guideline	Indian Council of Medical Research guidelines generally support the use of acyclovir for herpes simplex and varicella-zoster infections, with dose and duration based on the specific condition and patient factors. Consult your doctor for guidance that applies to your situation.

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Drug	Severity	Effect
Probenecid	Major
Mycophenolate mofetil	Major
Amphotericin B	Major
Aminoglycosides	Major
Tenofovir	Major
Cimetidine	Moderate
Theophylline	Moderate
Zidovudine	Moderate
Ibuprofen	Minor
Antacids	Minor

🚫 Contraindications

["Known severe allergic reaction or hypersensitivity to acyclovir, valacyclovir, or any ingredient in this medicine","Use of the oral tablet is not appropriate for serious infections such as herpes simplex encephalitis, which require intravenous therapy","Caution is needed in patients with significant kidney impairment, and dose adjustment is required","This medicine should not be used to treat infections caused by viruses other than herpes simplex or varicella-zoster virus"]

⚠️ Warnings & Precautions

["Take this medicine with plenty of water to help prevent kidney problems.","Elderly patients and those with kidney disease may need a lower dose or longer dosing interval.","This medicine can cause confusion, drowsiness, or hallucinations, especially in elderly patients or those with kidney problems. Avoid driving or operating machinery if you feel drowsy or confused.","This medicine does not cure herpes infections and does not prevent transmission of the virus to others. Practice safe sex and avoid close contact with open lesions.","Start treatment as early as possible after symptoms begin for the best chance of benefit.","Do not share this medicine with others, even if they have similar symptoms.","Tell your doctor about all other medicines you take, especially those that can affect the kidneys.","If you are pregnant, planning pregnancy, or breastfeeding, discuss the risks and benefits with your doctor."]

🤱 Lactation Safety

This medicine passes into breast milk in small amounts. It is generally considered compatible with breastfeeding because the amount transferred to the baby is low. However, you should consult your doctor before breastfeeding while taking this medicine, especially if your baby is premature or has kidney problems.

Additional Safety Advice

If you are planning pregnancy or are already pregnant, talk to your doctor before taking this medicine. Acyclovir is generally considered acceptable in pregnancy when there is a clear medical need, but the decision should be made with your doctor after weighing the risks and benefits. If you have recurrent genital herpes, your doctor may discuss ways to reduce the risk of passing the infection to your baby during delivery.

If you have recently had surgery, tell your surgeon and anesthesiologist that you are taking this medicine. This medicine can affect the kidneys, and surgery and anesthesia can also affect kidney function, so monitoring may be needed. Do not stop the medicine before surgery unless your doctor tells you to.

Tell your dentist that you are taking this medicine before any dental procedure. This medicine is sometimes prescribed around dental procedures in patients with a history of cold sores, but this is not a standard use for everyone. If you have an active cold sore, your dentist may advise postponing non-urgent dental work until the sore has healed to avoid spreading the virus.

Mild exercise such as walking is usually fine if you feel well enough. However, if you have shingles or another painful outbreak, rest may be more helpful. Avoid strenuous exercise if you feel dizzy, very tired, or have a fever. If you have kidney problems, talk to your doctor before starting a new exercise routine, because dehydration during exercise can increase the risk of kidney injury while taking this medicine.

Most people can continue their usual activities while taking this medicine, but you may feel tired or uncomfortable during the first few days of an outbreak. If you feel drowsy, confused, or dizzy, avoid driving or operating heavy machinery until you feel normal. If you have shingles, keep the rash covered and avoid close contact with pregnant women, newborns, and people with weak immunity until the blisters have dried and crusted over. Talk to your employer if you need to take time off during the most contagious period.

Do not stop this medicine on your own before completing the prescribed course, even if you feel better. Stopping early can allow the infection to return or worsen. If you develop a serious side effect such as kidney problems, severe confusion, or a severe allergic reaction, stop the medicine and seek medical help immediately. Your doctor will decide whether to stop the medicine, change the dose, or switch to another treatment.

This medicine is usually taken for short courses, so long-term effects are not common. When used for longer periods, especially in people with kidney disease or in elderly patients, there is a risk of kidney problems and neurological side effects such as confusion or drowsiness. Regular monitoring of kidney function may be needed during long-term use. If you need repeated courses, your doctor should review your condition and consider whether another antiviral or a different strategy is better for you.

🔄 Substitutes for nuclovir 800mg tablet

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[{"medicine":"Acyclovir 800 mg tablet","class":"Nucleoside analogue antiviral","typical_use":"Shingles, genital herpes, chickenpox","dosing_frequency":"Often 5 times a day for shingles","notes":"Low oral bioavailability; requires frequent dosing."},{"medicine":"Valacyclovir 1000 mg tablet","class":"Nucleoside analogue antiviral (prodrug)","typical_use":"Shingles, genital herpes, cold sores","dosing_frequency":"Usually 3 times a day for shingles","notes":"Better absorption than acyclovir; fewer daily doses."},{"medicine":"Famciclovir 500 mg tablet","class":"Nucleoside analogue antiviral","typical_use":"Shingles, genital herpes","dosing_frequency":"Usually 3 times a day","notes":"Different medicine; not interchangeable without medical advice."}]