aciherpin 800mg tablet

4.8 (12 reviews)

Acyclovir (800mg)

🏭 AGIO Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is aciherpin 800mg tablet used for?

Acivir 400 DT Tablet (Acyclovir) is used to treat ANTI INFECTIVES. It contains Acyclovir (800mg), which Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, the. Always consult your doctor before use. Take as prescribed.

Generic Name: Acyclovir
Manufacturer: AGIO Pharmaceuticals Ltd
Form: Allopathy
Pregnancy Category: B
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 aciherpin 800mg tablet Uses & Benefits

Herpes simplex infections (genital, oral, encephalitis), varicella-zoster (chickenpox, shingles).

Off-label uses: Herpes simplex prophylaxis in immunocompromised, EBV infection

📋 Drug Information

Generic Name(s)	Acyclovir
Brand Name	Acivir 400 DT Tablet
Manufacturer	AGIO Pharmaceuticals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Antiviral (Non-HIV) drugs
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAcyclovir is only partially absorbed from the gastrointestinal tract; oral bioavailability is 15-30%.

DistributionWidely distributed; crosses the blood-brain barrier and placenta; appears in breast milk.

Protein Binding9-33%

MetabolismHepatic; minor metabolism by aldehyde oxidase and alcohol dehydrogenase.

Half-Life2.5-3.3 hours (normal renal function); up to 20 hours in end-stage renal disease.

ExcretionRenal (62-90% as unchanged drug) via glomerular filtration and tubular secretion.

Bioavailability15-30%

Onset of ActionNot well defined; antiviral effect begins after conversion to active triphosphate.

Peak Plasma Time1.5-2 hours

Duration of ActionApproximately 8 hours (dosing interval dependent on renal function).

How It Works

Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, then to triphosphate by cellular kinases, which inhibits viral DNA polymerase and incorporates into viral DNA, causing chain termination.

Mechanism Steps

1Acyclovir enters virus-infected cells.

2Viral thymidine kinase converts acyclovir to acyclovir monophosphate.

3Cellular kinases convert monophosphate to diphosphate and triphosphate.

💡 How to Take aciherpin 800mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of aciherpin 800mg tablet

✅ Common Side Effects

Nausea
Diarrhea
Headache
Dizziness
Fatigue

🚨 Serious Side Effects

Acute renal failure
Neurotoxicity (confusion, hallucinations, seizures)
Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS)

⚠️ Rare Side Effects

Hepatitis
Stevens-Johnson syndrome
Anaphylaxis
Leukopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Probenecid	Major	Reduced renal clearance of acyclovir, increased plasma levels and toxicity risk.
Cimetidine	Major	Increased acyclovir AUC and half-life.
Mycophenolate mofetil	Major	Increased plasma levels of both drugs; monitor for toxicity.
Tenofovir	Moderate	Additive nephrotoxicity risk.
Aminoglycosides	Moderate	Increased risk of nephrotoxicity.
Cyclosporine	Moderate	Increased nephrotoxicity risk.
Tacrolimus	Moderate	Increased nephrotoxicity risk.
Zidovudine	Minor	Possible increased drowsiness.
Interferon	Minor	Possible additive antiviral effect.

🚨 Major Interactions

Probenecid
Cimetidine
Mycophenolate mofetil

⚡ Moderate Interactions

Tenofovir
Aminoglycosides
Cyclosporine
Tacrolimus

ℹ️ Minor Interactions

Zidovudine
Interferon

🍽️ Food Interactions

No significant food interactions; may be taken with or without food.

🍷 Alcohol Interaction

No known interaction; however, alcohol may exacerbate side effects like dizziness.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to acyclovir or valacyclovir.

📊 Monitoring Parameters

Renal function (especially in elderly or high-dose therapy); hydration status.

🤱 Lactation Safety

Caution; acyclovir is excreted in breast milk but considered compatible with breastfeeding.

💊 Overdose Management

Supportive care; hemodialysis may enhance elimination.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for aciherpin 800mg tablet

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Alternative brands with exact same active ingredient (Acyclovir (800mg)):

Medical Note: Always consult your doctor before switching medications.