Nortican P 75mg/10mg Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Thoughts of harming yourself or suicide
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing
- Irregular heartbeat, palpitations, or chest pain
- Severe skin rash, blisters, or peeling skin
- Yellowing of eyes or skin, dark urine, severe abdominal pain
- Unusual bleeding or bruising
- Severe dizziness or fainting
If experiencing severe symptoms, call emergency services immediately.
What is nortican p 75mg/10mg tablet used for?
This medicine is a combination of nortriptyline and pregabalin used to treat nerve pain. It works by altering pain signals in the brain and spinal cord. It is usually taken once daily at bedtime.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nortican p 75mg/10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा न्यूरोपैथिक दर्द (नसों से जुड़े दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह मधुमेह के कारण होने वाले नसों के दर्द, दाद के बाद होने वाले दर्द, और अन्य पुराने नसों के दर्द में राहत देती है। यह दवा दर्द के संकेतों को कम करके काम करती है। इसे आमतौर पर रात को सोने से पहले लिया जाता है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, धुंधली दृष्टि, वजन बढ़ना और हाथ-पैरों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको दिल की धड़कन अनियमित लगे, सांस लेने में तकलीफ हो, या त्वचा पर गंभीर दाने हों तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक गाड़ी न चलाएं। अगर आपको किडनी या दिल की बीमारी है, या पहले कभी अवसाद रहा है, तो डॉक्टर को बताएं। इस दवा को अचानक बंद न करें।
💊 nortican p 75mg/10mg tablet Uses & Benefits
[{"condition":"Painful diabetic neuropathy","description":"Helps reduce burning, shooting, or tingling pain in the feet and hands caused by diabetes-related nerve damage.","evidence":"Well-established"},{"condition":"Postherpetic neuralgia","description":"Relieves persistent nerve pain that can occur after a shingles infection.","evidence":"Well-established"},{"condition":"Chronic musculoskeletal pain","description":"May be used to manage long-standing pain from conditions like fibromyalgia or low back pain, though evidence is mixed.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed to prevent migraines, but not a first-line treatment.","evidence":"Limited"},{"condition":"Generalized anxiety disorder","description":"Nortriptyline component may help anxiety, but combination is not standard.","evidence":"Limited"}]
Primary treatment for: Neuropathic pain
Also treats: Diabetic neuropathy, Postherpetic neuralgia, Fibromyalgia
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nortican p 75mg/10mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different but complementary mechanisms. Nortriptyline works by blocking the reuptake of serotonin and norepinephrine in the brain, which helps to improve mood and reduce pain signals. Pregabalin binds to calcium channels on nerve cells, reducing the release of excitatory neurotransmitters like glutamate and substance P, which are involved in pain transmission. Together, they reduce abnormal nerve firing and alleviate neuropathic pain.
Mechanism Steps
💡 How to Take nortican p 75mg/10mg tablet
Strength: Tablet containing nortriptyline 75 mg and pregabalin 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once daily, preferably at bedtime due to sedative effects. However, the dose may be adjusted by your doctor based on your condition, response, and kidney function. Do not change the dose without consulting your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects, especially drowsiness, dizziness, and confusion. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Pregabalin requires dose adjustment in renal impairment. Nortriptyline may also require caution. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Nortriptyline is metabolized in the liver; dose reduction may be needed in hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (75 mg nortriptyline / 10 mg pregabalin). Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nortican p 75mg/10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Tramadol | Major | |
| Fluoxetine | Moderate | |
| Lisinopril | Moderate | |
| Ibuprofen | Moderate | |
| Antacid | Minor | |
| Cimetidine | Minor | |
| Diazepam | Major | |
| Morphine | Major | |
| Paroxetine | Major |
🚨 Major Interactions
- MAO inhibitors
- CNS depressants (e.g., opioids, benzodiazepines)
- Alcohol
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, quinidine)
- Antihypertensives
- NSAIDs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and impair judgment, and may worsen the sedative effects of both nortriptyline and pregabalin.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to nortriptyline or pregabalin","Concurrent use of MAO inhibitors","Recent myocardial infarction","Uncontrolled narrow-angle glaucoma","Severe renal impairment (for pregabalin component)"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until effects are known.","Do not stop abruptly; taper gradually to avoid withdrawal symptoms.","Use with caution in elderly due to increased risk of falls and confusion.","May worsen depression or suicidal thoughts; monitor closely.","Avoid alcohol and other CNS depressants.","Inform your doctor if you have kidney or liver disease."]
🤱 Lactation Safety
Nortriptyline and pregabalin are excreted in breast milk. Consult your doctor before breastfeeding; monitoring of infant for sedation is advised.
💊 Overdose Management
Overdose can cause severe drowsiness, confusion, irregular heartbeat, and difficulty breathing. Seek emergency medical help immediately. Treatment is supportive and symptomatic; there is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed. Do not crush, chew, or break the tablet unless your doctor advises. Avoid alcohol as it can increase drowsiness and dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have kidney problems, heart disease, or a history of depression or suicidal thoughts. Do not stop this medicine suddenly as it can cause withdrawal symptoms. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to side effects like drowsiness, dizziness, and confusion. Start with a lower dose and monitor closely for falls. Regular kidney function monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It may not be safe during pregnancy. Effective contraception is advised while on this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and increase sedation. Your doctor may advise temporary discontinuation before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth, increasing risk of dental problems. Also, it may interact with local anesthetics or sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also affect concentration; take precautions at work.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or no improvement after a reasonable trial, your doctor may decide to taper and stop. Abrupt discontinuation can cause withdrawal symptoms like headache, nausea, and anxiety.
📅 Long-Term Use Effects
Long-term use may lead to weight gain, peripheral edema, and tolerance. Regular monitoring of kidney and liver function is advised. Do not stop abruptly; taper gradually to avoid withdrawal symptoms. Periodic review with your doctor is necessary to assess continued benefit.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedHelps manage chronic pain and improve coping skills.
Evidence: ModerateMay provide additional pain relief.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. If traveling across time zones, adjust dosing times gradually in consultation with your doctor. Store at room temperature and protect from moisture. Check customs regulations for controlled substances; carry a doctor's letter if needed.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief may begin within a few days, but full effect can take 2 to 4 weeks.
A: No, stopping suddenly can cause withdrawal symptoms. Always taper under medical supervision.
A: No, alcohol can increase drowsiness and dizziness. Avoid alcohol.
A: If less than 12 hours late, take it as soon as you remember. If more than 12 hours late, skip the missed dose. Do not double dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is a simple painkiller.
Fact: It is not a simple painkiller; it works on the nervous system to reduce nerve pain. - Myth: It is addictive.
Fact: It has low potential for abuse, but dependence can occur; do not stop suddenly. - Myth: It can be taken for any type of pain.
Fact: It is specifically for neuropathic pain, not for headaches or muscle pain.
🔄 Alternative Options
Generic Alternatives
- Nortriptyline 75 mg + Pregabalin 10 mg tablet