Gushout Tablet: Complete Medicine Guide For Patients
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat or palpitations
- Severe muscle weakness or paralysis
- Difficulty breathing or shortness of breath
- Confusion or extreme drowsiness
- Severe diarrhea leading to dehydration
- Swelling of face, lips, or throat
- Blood in urine or severe flank pain
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is noculi tablet used for?
This medicine is a prescription tablet containing Potassium Magnesium Citrate 978 mg. It is used to prevent and treat certain kidney stones by making urine less acidic, and to replenish potassium and magnesium in the body. It is taken orally with meals, usually once or twice daily, as directed by a doctor.
- Generic Name: Potassium Magnesium Citrate (978mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 noculi tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पोटैशियम मैग्नीशियम सिट्रेट 978 मिलीग्राम की एक प्रिस्क्रिप्शन टैबलेट है। इसका उपयोग मुख्य रूप से गुर्दे की पथरी (किडनी स्टोन) को रोकने और उसके इलाज में किया जाता है, खासकर यूरिक एसिड और सिस्टीन की पथरी में। यह पेशाब को कम अम्लीय बनाकर पथरी को घोलने में मदद करती है। इसके अलावा, यह शरीर में पोटैशियम और मैग्नीशियम की कमी को पूरा करती है, जो दिल, मांसपेशियों और नसों के सामान्य कामकाज के लिए जरूरी हैं। यह दवा डिस्टल रीनल ट्यूबुलर एसिडोसिस, हाइपोकैलिमिया और हाइपोमैग्नेसीमिया जैसी स्थितियों में भी दी जाती है। इसे डॉक्टर की सलाह के अनुसार ही लें, खुद से नहीं।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में दस्त, मतली, पेट में असहजता और उल्टी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी मांसपेशियों में कमजोरी, थकान या दिल की धड़कन धीमी हो सकती है, अगर पोटैशियम या मैग्नीशियम का स्तर बहुत ज्यादा बढ़ जाए। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको दिल की धड़कन में अनियमितता, सांस लेने में तकलीफ, या चेहरे पर सूजन महसूस हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को खुद से कम या ज्यादा न करें। इसे भोजन के साथ पूरे पानी के साथ निगलें। दिनभर पर्याप्त पानी पिएं, जब तक डॉक्टर ने तरल पदार्थों पर रोक न लगाई हो। पोटैशियम सप्लीमेंट या नमक के विकल्प जिनमें पोटैशियम हो, उन्हें इस दवा के साथ न लें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं, खासकर ब्लड प्रेशर की दवाएं, डाइयूरेटिक्स और दर्द निवारक। नियमित रूप से खून की जांच कराएं ताकि पोटैशियम, मैग्नीशियम और गुर्दे की कार्यप्रणाली की निगरानी हो सके। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 noculi tablet Uses & Benefits
[{"condition":"Uric acid kidney stones","description":"This medicine alkalinizes the urine, which helps dissolve uric acid stones and prevents new ones from forming.","evidence":"Well-established"},{"condition":"Cystine kidney stones","description":"By increasing urine pH, this medicine helps dissolve cystine stones and reduces the risk of recurrence.","evidence":"Well-established"},{"condition":"Distal renal tubular acidosis","description":"This medicine corrects the metabolic acidosis and replenishes potassium and magnesium in patients with this condition.","evidence":"Well-established"},{"condition":"Hypokalemia","description":"It provides potassium to treat or prevent low potassium levels when other treatments are not suitable.","evidence":"Well-established"},{"condition":"Hypomagnesemia","description":"It supplies magnesium to correct low magnesium levels in the body.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of calcium oxalate stones","description":"Sometimes used off-label to reduce calcium oxalate stone formation by increasing urinary citrate, which inhibits crystal aggregation.","evidence":"Limited"},{"condition":"Chronic metabolic acidosis","description":"May be used off-label to correct mild metabolic acidosis in conditions like chronic kidney disease, but this requires careful monitoring.","evidence":"Limited"}]
Primary treatment for: Kidney stones (uric acid and cystine)
Also treats: Distal renal tubular acidosis, Hypokalemia, Hypomagnesemia, Chronic metabolic acidosis
📋 Drug Information
| Generic Name(s) | Potassium Magnesium Citrate (978mg) |
| Brand Name | noculi tablet |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | Minerals |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a cool, dry place away from direct sunlight and moisture. Do not refrigerate unless specified by the manufacturer. Keep the tablets in their original container, tightly closed. Keep out of reach of children and pets. |
| Shelf Life | Not established from the available information. Refer to the packaging for the expiry date. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by providing citrate, potassium, and magnesium. Citrate is metabolized in the body to bicarbonate, which neutralizes acid and raises the pH of urine. This alkalinization makes the urine less acidic, which increases the solubility of uric acid and cystine, helping to dissolve existing stones and prevent new ones from forming. Potassium and magnesium are essential electrolytes that are replenished by this medicine. Magnesium also acts as a natural inhibitor of calcium oxalate crystal formation in the urine. Additionally, citrate binds to calcium in the urine, reducing the amount of free calcium available to form stones with oxalate. The combined effect helps maintain normal electrolyte balance and reduces the risk of stone recurrence.
Mechanism Steps
💡 How to Take noculi tablet
Strength: Potassium Magnesium Citrate 978 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally, typically once or twice daily, or as directed by your physician. The exact dose and frequency depend on the indication, your kidney function, and your electrolyte levels. For kidney stone prevention, the dose may be adjusted to achieve a target urine pH. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially if they have reduced kidney function or heart disease. Dose adjustment may be necessary based on kidney function and electrolyte levels. Regular monitoring is recommended. Consult your doctor for personalized dosing. |
| Renal Impairment | In patients with mild to moderate renal impairment, this medicine should be used with caution and dose adjustment may be required. It is contraindicated in severe renal impairment (eGFR <30 mL/min). Regular monitoring of kidney function and electrolytes is essential. Consult your doctor for specific dosing recommendations. |
| Hepatic Impairment | No specific dose adjustment is established for patients with hepatic impairment. However, citrate is metabolized in the liver, so caution is advised in severe liver disease. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of noculi tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Spironolactone | Major | |
| Lisinopril | Major | |
| Potassium supplements | Major | |
| Magnesium hydroxide | Major | |
| Ibuprofen | Moderate | |
| Furosemide | Moderate | |
| Prednisone | Moderate | |
| Aluminum hydroxide | Minor | |
| Ferrous sulfate | Minor | |
| Calcium carbonate | Minor |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone, amiloride, triamterene)
- ACE inhibitors (e.g., lisinopril, enalapril) and ARBs (e.g., losartan, valsartan)
- Potassium supplements
- Magnesium-containing antacids or laxatives
⚡ Moderate Interactions
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Corticosteroids
- Loop diuretics (e.g., furosemide) and thiazide diuretics
🍷 Alcohol Interaction
Alcohol may worsen dehydration and electrolyte imbalances. It can also increase the risk of stomach upset and diarrhea. It is advisable to limit or avoid alcohol while taking this medicine, especially if you have kidney problems or are prone to electrolyte imbalances.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Use with caution in patients with mild to moderate kidney disease; dose adjustment may be needed.","Monitor potassium and magnesium levels regularly, especially in patients with heart or kidney disease.","Avoid concurrent use with potassium supplements or salt substitutes containing potassium.","Use with caution in patients taking ACE inhibitors, ARBs, or potassium-sparing diuretics.","May cause gastrointestinal upset; take with food to minimize.","Do not use in patients with severe dehydration or electrolyte imbalances.","Consult your doctor before using any over-the-counter medicines, especially antacids or laxatives containing magnesium.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children.","Do not exceed the prescribed dose."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Potassium and magnesium are normal components of breast milk, but the amounts from this medicine may affect the infant. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can lead to hyperkalemia, hypermagnesemia, and metabolic alkalosis. Symptoms may include muscle weakness, irregular heartbeat, confusion, nausea, and diarrhea. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, calcium gluconate for cardiac protection, and measures to lower potassium and magnesium levels. Dialysis may be required in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Swallow the tablet whole with a full glass of water, preferably with meals to reduce stomach upset. Drink plenty of water throughout the day unless your doctor has restricted your fluid intake. Avoid taking potassium supplements or salt substitutes containing potassium while on this medicine, as this can raise your potassium levels dangerously. Inform your doctor about all other medicines you are taking, especially blood pressure medicines, diuretics, and pain relievers. Keep all scheduled blood tests to monitor your potassium, magnesium, and kidney function. Do not use this medicine if you have severe kidney disease, high potassium, or high magnesium levels. Pregnant or breastfeeding women should consult their doctor before using this medicine. Store it in a cool, dry place away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function and may be more sensitive to electrolyte imbalances. This medicine should be used with caution, and doses may need adjustment based on kidney function. Regular monitoring of potassium, magnesium, and kidney function is recommended. Elderly patients should also be monitored for signs of dehydration and diarrhea.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Potassium and magnesium are essential during pregnancy, but excessive amounts can be harmful. Your doctor will assess whether this medicine is appropriate for you and may adjust the dose or recommend alternatives.
🏥 Post-Surgery Considerations
After surgery, your electrolyte levels and kidney function may be affected. Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped or adjusted around the time of surgery, especially if you are not able to eat or drink. Follow your doctor's instructions carefully.
🦷 Dental Procedures
This medicine does not typically interfere with dental procedures. However, inform your dentist that you are taking it, especially if you have kidney or heart conditions. Maintain good oral hygiene and stay hydrated.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine is not known to impair exercise capacity. However, if you experience muscle weakness, dizziness, or fatigue, avoid strenuous exercise until you consult your doctor. Stay well hydrated during exercise, especially if you are taking this medicine for kidney stones.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is not known to affect your ability to drive or operate machinery. However, if you experience dizziness, fatigue, or muscle weakness, avoid these activities until you feel better. The medicine may cause diarrhea, which can be inconvenient at work; taking it with food can help. Overall, it should not significantly impact your daily work life when taken as prescribed.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor may decide to stop it if your electrolyte levels become abnormal, your kidney function worsens, or your condition improves. If you experience serious side effects, seek medical advice immediately; your doctor will determine whether to stop or adjust the dose.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. It helps prevent kidney stone recurrence and maintains electrolyte balance. However, prolonged use can lead to hyperkalemia, hypermagnesemia, or metabolic alkalosis, especially if kidney function declines. Regular monitoring of blood electrolytes, kidney function, and urine pH is essential. Your doctor may adjust the dose or stop the medicine if any abnormalities are detected. Long-term use should be reviewed periodically to ensure it remains appropriate for your condition.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing fluid intake, reducing sodium and animal protein, and eating citrate-rich fruits can help prevent kidney stones.
Evidence: Well-establishedMay be used if magnesium supplementation is not needed.
Evidence: Well-establishedFor uric acid stones, allopurinol reduces uric acid production and may be used along with alkalinization.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, always inform your healthcare provider about all medicines you are taking before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C).
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container, tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Keep the medicine in your carry-on luggage to avoid loss or temperature extremes. Store it at room temperature and away from direct sunlight. If crossing time zones, continue taking your doses at the same intervals as prescribed; you may need to adjust timing gradually. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts alkalinizing your urine within a few hours, but it may take several days to weeks to achieve the full protective effect. Your doctor will monitor your urine pH and electrolyte levels to adjust the dose.
A: It depends on the other medications. This medicine can interact with potassium-sparing diuretics, ACE inhibitors, ARBs, and potassium supplements, increasing the risk of high potassium. Always inform your doctor about all medicines you take.
A: Diarrhea is a common side effect. Stay hydrated and take the medicine with food. If diarrhea is severe or persistent, contact your doctor, as it may lead to dehydration and electrolyte imbalance.
A: This medicine is generally safe for kidneys when used as prescribed and monitored. However, it is contraindicated in severe kidney disease. Your doctor will check your kidney function regularly.
A: No, do not stop without consulting your doctor. This medicine is often used long-term to prevent stone recurrence. Stopping suddenly may increase the risk of new stones.
🤔 Common Patient Concerns
🔄 Substitutes for noculi tablet
View AllAlternative brands with exact same active ingredient:
-
potrate-m 978mg tabletIntas Pharmaceuticals Ltd ₹36.92 46.1% CHEAPER
-
gushout tabletLa Renon Healthcare Pvt Ltd ₹70.31 2.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can dissolve all types of kidney stones.
Fact: This medicine is effective mainly for uric acid and cystine stones. It is not effective for calcium oxalate stones, although it may help prevent them. - Myth: I can stop taking this medicine once my stones are gone.
Fact: This medicine is often used long-term to prevent stone recurrence. Stopping without medical advice may lead to new stones. - Myth: This medicine is a painkiller for kidney stone pain.
Fact: This medicine does not relieve acute pain. It works by altering urine chemistry to prevent and dissolve certain stones. - Myth: Taking extra potassium is always safe.
Fact: Too much potassium can be dangerous, causing heart rhythm problems. This medicine should only be taken as prescribed.
🔄 Alternative Options
Generic Alternatives
- Potassium Magnesium Citrate 978 mg tablet
Brand Alternatives
- Gushout Tablet