niveoli inhaler - Beclometasone (100mcg) + Formoterol (6mcg) medicine

Duomate 100mcg/6mcg Transhaler: Complete Medicine Guide

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🏭 Cipla Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 29, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for asthma and COPD maintenance.
Reviewed by
SaathiMed Expert Panel | Oct 29, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or worsening of asthma symptoms after using the inhaler
  • Severe allergic reaction with rash, swelling, or difficulty breathing
  • Chest pain, fast or irregular heartbeat
  • Signs of adrenal insufficiency: fatigue, weakness, nausea, low blood pressure
  • Vision changes or eye pain
  • White patches in the mouth or throat

If experiencing severe symptoms, call emergency services immediately.

What is niveoli inhaler used for?

This medicine is a combination inhaler used for the maintenance treatment of asthma and COPD. It contains beclometasone (a steroid) and formoterol (a long-acting bronchodilator). It is not for acute attacks.

  • Generic Name: Beclometasone (100mcg) + Formoterol (6mcg)
  • Manufacturer: Cipla Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 niveoli inhaler के बारे में (Hindi Summary)

उपयोग: यह दवा बेक्लोमेथासोन और फॉर्मोटेरोल का संयोजन है, जिसका उपयोग अस्थमा और सीओपीडी के नियमित इलाज के लिए किया जाता है। यह इनहेलर फेफड़ों में सूजन कम करता है और सांस की नलियों को खोलता है, जिससे सांस लेने में आसानी होती है। यह दवा तुरंत राहत के लिए नहीं है, बल्कि लंबे समय तक नियंत्रण के लिए है। इसे डॉक्टर के बताए अनुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में गले में जलन, आवाज में भारीपन, सिरदर्द और हाथ-पैरों में कंपन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, दिल की धड़कन तेज होना, या सांस लेने में कठिनाई हो सकती है। लंबे समय तक उपयोग से मुंह में फंगल संक्रमण, आंखों की समस्या हो सकती है। कोई भी असामान्य लक्षण दिखने पर डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग केवल डॉक्टर के निर्देशानुसार करें। यह तुरंत राहत के लिए नहीं है। हर बार उपयोग के बाद मुंह को पानी से धोएं। दवा की मात्रा न बढ़ाएं। आपात स्थिति के लिए रेस्क्यू इनहेलर हमेशा साथ रखें। दिल, मधुमेह, थायरॉइड या लिवर की बीमारी हो तो डॉक्टर को बताएं। दवा अचानक बंद न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 niveoli inhaler Uses & Benefits

[{"condition":"Asthma","description":"Maintenance treatment to prevent asthma symptoms and reduce exacerbations in patients requiring combination therapy.","evidence":"Well-established"},{"condition":"Chronic Obstructive Pulmonary Disease (COPD)","description":"Regular use to improve lung function and reduce symptoms in patients with COPD who need dual bronchodilation and anti-inflammatory therapy.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Asthma

Also treats: Chronic Obstructive Pulmonary Disease (COPD)

📋 Drug Information

Generic Name(s)Beclometasone (100mcg) + Formoterol (6mcg)
Brand Nameniveoli inhaler
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationInhalation
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not puncture or incinerate the inhaler. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Rinse your mouth with water after each use to prevent oral thrush.
2
Use this medicine at the same times each day for best results.
3
Do not use this inhaler for sudden breathing problems; always carry a rescue inhaler.
4
Keep track of your doses using the dose counter on the inhaler.
5
Inform your doctor if you have heart disease, diabetes, or thyroid problems before using this medicine.
6
Do not stop this medicine abruptly without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing
This medicine is commonly prescribed for wheezing due to asthma or COPD.
Likely Use
✅
Shortness of breath
It helps prevent shortness of breath when used regularly.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAfter inhalation, a portion of the dose is deposited in the lungs and absorbed into the bloodstream. The remainder is swallowed and absorbed from the gastrointestinal tract. Peak plasma concentrations of formoterol are typically reached within 10 to 20 minutes after inhalation. Beclometasone is absorbed more slowly, with peak levels occurring within 1 to 2 hours.
DistributionBoth drugs are distributed widely in the body. Formoterol has a volume of distribution of approximately 4 L/kg. Beclometasone and its active metabolite have a volume of distribution of about 20 L. Plasma protein binding is moderate to high for both compounds.
Protein BindingFormoterol is about 50% bound to plasma proteins. Beclometasone and its active metabolite are approximately 87% bound to plasma proteins.
MetabolismFormoterol is metabolized primarily by glucuronidation and O-demethylation. Beclometasone is rapidly converted by esterase enzymes to an active metabolite, beclometasone-17-monopropionate, which is further metabolized. Both drugs undergo extensive first-pass metabolism for the swallowed portion.
Half-LifeThe elimination half-life of formoterol is approximately 10 hours. The active metabolite of beclometasone has a half-life of about 2.7 hours.
ExcretionFormoterol is excreted mainly in urine and feces. Beclometasone metabolites are excreted primarily in feces and urine.
BioavailabilityThe systemic bioavailability of inhaled formoterol is about 46% of the delivered dose. For beclometasone, the pulmonary bioavailability is approximately 50% of the inhaled dose, while the oral bioavailability is very low due to first-pass metabolism.
Onset of ActionFormoterol provides bronchodilation within 5 minutes of inhalation. Beclometasone's anti-inflammatory effects develop over hours to days.
Peak Plasma TimeFormoterol: 10-20 minutes; Beclometasone: 1-2 hours.
Duration of ActionFormoterol provides bronchodilation for up to 12 hours. Beclometasone's anti-inflammatory effect lasts longer and is maintained with regular dosing.

How It Works

This medicine combines two active ingredients with complementary actions. Beclometasone is a corticosteroid that binds to glucocorticoid receptors inside cells, reducing the production of inflammatory substances and suppressing the migration of inflammatory cells into the airways. Formoterol is a long-acting beta-2 adrenergic agonist that selectively stimulates beta-2 receptors on airway smooth muscle, causing relaxation and bronchodilation. Together, they reduce inflammation and keep the airways open, improving breathing and preventing symptoms.

Mechanism Steps

1
Beclometasone binds to glucocorticoid receptors: Beclometasone enters cells and binds to glucocorticoid receptors in the cytoplasm, leading to translocation into the nucleus and modulation of gene transcription.
2
Reduction of inflammatory mediators: This binding reduces the production of pro-inflammatory cytokines, chemokines, and adhesion molecules, and decreases the survival of inflammatory cells like eosinophils.
3
Formoterol stimulates beta-2 receptors: Formoterol binds to beta-2 adrenergic receptors on airway smooth muscle cells, activating adenylate cyclase and increasing cyclic AMP levels.
4
Airway smooth muscle relaxation: Increased cyclic AMP leads to relaxation of bronchial smooth muscle, resulting in bronchodilation and improved airflow.
5
Complementary clinical effect: The anti-inflammatory action of beclometasone and the bronchodilator action of formoterol work together to control symptoms and reduce exacerbations.

💡 How to Take niveoli inhaler

Strength: Each actuation delivers beclometasone 100mcg and formoterol 6mcg.

1Open the inhaler cover.
2Shake the inhaler gently.
3Breathe out fully.
4Place the mouthpiece in your mouth and close your lips around it.
5Breathe in deeply and steadily through your mouth.
6Remove the inhaler and hold your breath for 10 seconds.
7Breathe out slowly.
8Close the inhaler and rinse your mouth with water.
9If a second dose is prescribed, wait 30 seconds and repeat.

Dosage Information

Adult DosageThe usual adult dose is one inhalation twice daily (morning and evening). The dose may be adjusted by your doctor based on your condition and response. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but use with caution due to increased risk of cardiovascular effects and other age-related conditions.
Renal ImpairmentNo specific dose adjustment is required for renal impairment, but use with caution.
Hepatic ImpairmentUse with caution in patients with severe hepatic impairment. Dose adjustment may be necessary.
Maximum Daily DoseThe maximum recommended daily dose is two inhalations (200mcg beclometasone/12mcg formoterol) per day. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of niveoli inhaler

✅ Common Side Effects

Throat irritation (Common (1-10%))
Rinse mouth with water after use. If persists, consult doctor.
Hoarseness (Common (1-10%))
Rinsing mouth may help. Report to doctor if severe.
Headache (Common (1-10%))
Usually resolves. Use mild pain reliever if needed, but consult doctor.
Tremor (Common (1-10%))
Usually transient. If bothersome, consult doctor.
Palpitations (Uncommon (0.1-1%))
Monitor. If persistent or severe, seek medical advice.

🚨 Serious Side Effects

Severe allergic reactions (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, swelling, or difficulty breathing.
Adrenal insufficiency (Rare (<0.1%))
Contact doctor if you experience fatigue, weakness, nausea, or low blood pressure.
Paradoxical bronchospasm (Rare (<0.1%))
Stop use and seek immediate medical attention if breathing worsens after inhalation.
Increased heart rate or irregular heartbeat (Rare (<0.1%))
Seek medical attention if you experience palpitations, chest pain, or fainting.
Glaucoma or cataracts (Rare (<0.1%))
Regular eye check-ups recommended. Report vision changes to doctor.

⚠️ Rare Side Effects

Hyperglycemia
Monitor blood sugar if diabetic. Consult doctor if levels rise.
Hypokalemia
Report muscle weakness or cramps to doctor.
Behavioral changes
Consult doctor if mood or behavior changes occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Propranolol Major
Furosemide Moderate
Theophylline Moderate
Prednisone Moderate
Ritonavir Major
Amitriptyline Major
Phenelzine Major
Hydrochlorothiazide Moderate
Diphenhydramine Minor

🚨 Major Interactions

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Xanthine derivatives (e.g., theophylline)
  • Other corticosteroids

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness and drowsiness. It is advisable to limit alcohol consumption while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to beclometasone, formoterol, or any component of the formulation.","Not for acute asthma attacks or status asthmaticus.","Severe hypersensitivity to milk proteins (if applicable to formulation)."]

⚠️ Warnings & Precautions

["Do not use for acute bronchospasm; use a short-acting beta-2 agonist instead.","Rinse mouth after each use to prevent oral candidiasis.","Use with caution in patients with cardiovascular disorders, especially coronary insufficiency, arrhythmias, and hypertension.","Use with caution in patients with convulsive disorders, thyrotoxicosis, diabetes mellitus, and ketoacidosis.","Do not exceed recommended dose; serious cardiovascular effects may occur.","Long-term use may lead to systemic corticosteroid effects such as adrenal suppression, osteoporosis, and growth retardation in children.","Transfer from systemic corticosteroids to inhaled therapy should be done gradually and under medical supervision.","Monitor for signs of adrenal insufficiency during periods of stress or trauma."]

🤱 Lactation Safety

It is not known whether beclometasone and formoterol pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause symptoms such as tremor, palpitations, tachycardia, and hypokalemia. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac function and serum potassium levels.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Use this medicine only as prescribed for regular maintenance, not for acute attacks. Rinse your mouth with water after each use to prevent oral thrush. Do not exceed the recommended dose. Keep a rescue inhaler available at all times. Inform your doctor if you have heart disease, diabetes, thyroid problems, or liver disease. Do not stop this medicine abruptly without medical advice. Store the inhaler properly and check the dose counter regularly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to cardiovascular effects of formoterol. Use with caution and monitor heart rate and blood pressure regularly.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. The safety of this combination during pregnancy is not fully established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may need to be continued or adjusted perioperatively.

🦷 Dental Procedures

Inform your dentist about this medicine. Rinsing with water after use can help prevent oral thrush, which is important for dental health.

💚 Lifestyle Tips for Better Results

🏃
Avoid triggers such as smoke, dust, and pollen.
🥗
Maintain a healthy weight to reduce strain on your lungs.
😴
Practice breathing exercises as advised by your doctor.
💧
Get vaccinated against flu and pneumonia.
🧘
Keep your home well-ventilated and clean.

🏋️ Exercise Considerations

Exercise is generally safe and encouraged, but if you experience exercise-induced bronchospasm, use your rescue inhaler before exercise. Consult your doctor for personalized advice.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Stay hydrated to keep airways moist.
Limit processed foods and excess salt.

💼 Impact on Daily Work & Life

This medicine does not usually affect your ability to work or drive. However, if you experience dizziness or tremor, avoid driving or operating machinery until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Stopping suddenly can cause your symptoms to worsen. Your doctor may gradually reduce the dose if appropriate.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to oral thrush, hoarseness, and systemic corticosteroid effects such as adrenal suppression, osteoporosis, and growth retardation in children. Regular monitoring of lung function, adrenal function, and eye health is recommended. Use the lowest effective dose to minimize risks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Montelukast

An oral medication that can help control asthma symptoms, but not as effective as inhaled combination therapy.

Evidence: Well-established
Immunotherapy

Allergy shots may reduce asthma symptoms in allergic individuals.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Annual influenza vaccination is recommended for patients with asthma or COPD. Pneumococcal vaccination may also be advised. Consult your doctor for personalized recommendations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not puncture or incinerate

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom

✈️ Traveling with This Medicine

Carry your inhaler in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid extreme temperatures. If traveling across time zones, continue your doses at regular intervals as prescribed. Check customs regulations for carrying prescription inhalers. Store away from direct sunlight and heat.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with moderate asthma
She was prescribed this medicine for daily maintenance. Initially, she used it only when she felt breathless, but her doctor explained it must be used regularly. After using it twice daily for a month, her night-time awakenings reduced significantly, and she could exercise without wheezing.
💡 Lesson: Consistent daily use of maintenance inhalers is key to controlling asthma, even when you feel fine.
👤 A 60-year-old man with COPD
He had frequent flare-ups and was started on this combination inhaler. He learned to rinse his mouth after each dose and to use his rescue inhaler for sudden symptoms. Over six months, his hospital visits decreased, and his breathing improved.
💡 Lesson: Proper inhaler technique and adherence to the prescribed regimen can greatly improve COPD management.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Formoterol starts working within 5 minutes, but the full anti-inflammatory effect of beclometasone may take several days to weeks.

Q: Can I use this inhaler during an asthma attack?

A: No, this is a maintenance inhaler and should not be used for sudden attacks. Use a rescue inhaler for immediate relief.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for niveoli inhaler

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This inhaler can be used for immediate relief during an asthma attack.
    Fact: This medicine is for maintenance only. It does not provide rapid relief. Always use a rescue inhaler for acute symptoms.
  • Myth: Inhaled steroids are addictive.
    Fact: Inhaled corticosteroids are not addictive. They are safe and effective for long-term control of asthma and COPD.
  • Myth: Once symptoms improve, the inhaler can be stopped.
    Fact: Do not stop this medicine without consulting your doctor. Stopping suddenly can worsen your condition.

📊 Comparison with Similar Medicines

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