nimuviz p 100mg/325mg tablet - Information coming soon medicine

Nimuviz P 100mg/325mg Tablet: Complete Medicine Guide

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Information coming soon
🏭 Generic 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 30, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for short-term use in acute pain; limited for long-term use.
Reviewed by
SaathiMed Expert Panel | Oct 30, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is nimuviz p 100mg/325mg tablet used for?

This medicine is a combination of nimesulide and paracetamol used for short-term relief of acute pain, inflammation, and fever. It works by reducing prostaglandins that cause pain and swelling. It should be taken with food and not exceeding 2 tablets in 24 hours.

  • Generic Name: Information coming soon
  • Manufacturer: Multiple manufacturers
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nimuviz p 100mg/325mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा निमेसुलाइड और पैरासिटामोल का संयोजन है, जिसका उपयोग तीव्र दर्द, सूजन और बुखार से राहत के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, सर्जरी के बाद के दर्द और बुखार में प्रभावी है। यह दवा सूजन पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। इसे भोजन के साथ लेना चाहिए और 24 घंटे में 2 गोलियों से अधिक नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन पेट में रक्तस्राव, अल्सर, लीवर की क्षति, गुर्दे की समस्या और गंभीर एलर्जी प्रतिक्रिया हो सकती है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, आंखों या त्वचा का पीलापन, पेशाब में कमी, या चेहरे, होंठ या गले में सूजन हो, तो तुरंत चिकित्सा सहायता लें।

सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या अवधि से अधिक न लें। पेट की परेशानी कम करने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे लीवर की क्षति और पेट में रक्तस्राव का खतरा बढ़ जाता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक या NSAIDs न लें। यदि आपको पेट के अल्सर, लीवर या गुर्दे की बीमारी, उच्च रक्तचाप या हृदय रोग का इतिहास है, तो अपने डॉक्टर को बताएं। गर्भावस्था के दौरान इस दवा का उपयोग न करें, खासकर तीसरी तिमाही में। स्तनपान कराने से पहले अपने डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 nimuviz p 100mg/325mg tablet Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgery.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever due to the paracetamol component.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"May be used for short-term relief of pain and stiffness in osteoarthritis.","evidence":"Limited"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used for menstrual cramps, but other NSAIDs are preferred.","evidence":"Limited"}]

Primary treatment for: Acute pain and inflammation

Also treats: Musculoskeletal pain, Dental pain, Post-operative pain, Fever

📋 Drug Information

Generic Name(s)Information coming soon
Brand Namenimuviz p 100mg/325mg tablet
ManufacturerMultiple manufacturers
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the recommended dose of 2 tablets in 24 hours.
3
Avoid alcohol while taking this medicine to prevent liver damage.
4
Do not use this medicine for more than 7 days without consulting your doctor.
5
Inform your doctor if you have a history of stomach ulcers, liver, or kidney disease.
6
Report any unusual bleeding, bruising, or yellowing of the eyes immediately.
7
Do not take other pain relievers or NSAIDs without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Acute pain
This medicine is commonly prescribed for acute pain.
Likely Use
✅
Fever
This medicine contains paracetamol which reduces fever.
Likely Use
❌
Chronic pain
This medicine is not recommended for long-term use.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNimesulide is rapidly absorbed from the gastrointestinal tract after oral administration. Paracetamol is also well absorbed. Food may slightly delay the absorption of both components.
DistributionNimesulide is highly protein-bound and distributes widely into tissues, including synovial fluid. Paracetamol distributes throughout most body fluids.
Protein BindingNimesulide: >97% bound to plasma proteins. Paracetamol: <20% bound to plasma proteins.
MetabolismNimesulide is extensively metabolized in the liver, primarily by CYP2C9 to its major metabolite, 4-hydroxynimesulide, which is pharmacologically active. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction oxidized by CYP2E1 to a toxic metabolite, NAPQI, which is detoxified by glutathione.
Half-LifeNimesulide: 1.8-4.7 hours; Paracetamol: 2-3 hours.
ExcretionNimesulide metabolites are excreted mainly in urine (about 70%) and feces (about 20%). Paracetamol metabolites are excreted in urine.
BioavailabilityNimesulide: approximately 90%; Paracetamol: approximately 80-90%.
Onset of ActionPain relief typically begins within 30 minutes to 1 hour after oral administration.
Peak Plasma TimeNimesulide: 1.5-2.5 hours; Paracetamol: 0.5-1 hour.
Duration of ActionPain relief lasts approximately 4-6 hours, so dosing is usually every 8-12 hours as needed.

How It Works

This medicine combines two analgesics with different mechanisms. Nimesulide selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, leading to pain relief and fever reduction. The combination provides additive analgesic and antipyretic effects.

Mechanism Steps

1
COX-2 inhibition by nimesulide: Nimesulide binds to and inhibits the COX-2 enzyme, reducing the conversion of arachidonic acid to prostaglandin H2, a precursor of pain and inflammation mediators.
2
Reduced prostaglandin synthesis: Decreased prostaglandin levels lead to less sensitization of pain receptors and reduced inflammation.
3
Central action of paracetamol: Paracetamol acts on the hypothalamus to reduce fever and on the central nervous system to increase pain threshold.
4
Additive analgesic effect: The combination of peripheral and central mechanisms results in enhanced pain relief compared to either agent alone.

💡 How to Take nimuviz p 100mg/325mg tablet

Strength: Tablet containing nimesulide 100 mg and paracetamol 325 mg.

1Take this medicine orally with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the prescribed dose and duration exactly.
5Do not take more than 2 tablets in 24 hours.
6If you miss a dose, take it as soon as you remember, but do not double dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet (nimesulide 100 mg + paracetamol 325 mg) taken orally every 8 to 12 hours as needed for pain and fever. The maximum recommended dose is two tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration. Take with food to reduce stomach upset.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney disease. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseMaximum 2 tablets (nimesulide 200 mg + paracetamol 650 mg) in 24 hours.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage and gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nimuviz p 100mg/325mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated. If severe or persistent, consult your doctor.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. If severe, consult your doctor.
Heartburn (Common (5-10%))
Take with food. Avoid lying down immediately after taking. Consult doctor if persistent.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if it lasts more than 2 days.
Headache (Common (5-10%))
Usually resolves. If severe or persistent, consult your doctor.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or bloody stools, vomiting blood, or severe abdominal pain.
Liver damage (Rare (<0.1%))
Seek immediate medical attention if you experience yellowing of skin or eyes, dark urine, or severe fatigue.
Kidney problems (Rare (<0.1%))
Seek immediate medical attention if you notice decreased urination, swelling, or confusion.
Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, or throat, difficulty breathing, or severe rash.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek immediate medical attention if you develop a painful rash with blisters or peeling skin.
Agranulocytosis
Seek immediate medical attention if you develop fever, sore throat, or mouth ulcers.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
ACE inhibitors/ARBs Major
Diuretics Moderate
Lithium Moderate
SSRIs Moderate
Alcohol Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, diclofenac)
  • Corticosteroids
  • Methotrexate
  • ACE inhibitors and ARBs

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Lithium
  • SSRIs
  • Alcohol

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage, especially due to the paracetamol component, and increases the risk of gastrointestinal bleeding due to the nimesulide component.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to nimesulide, paracetamol, or any component of the formulation","Active peptic ulcer or history of recurrent ulcers","Severe liver impairment","Severe kidney impairment","History of gastrointestinal bleeding or perforation related to NSAID use","Severe heart failure","Children under 12 years of age","Pregnancy (especially third trimester)","Breastfeeding"]

⚠️ Warnings & Precautions

["Take the lowest effective dose for the shortest possible duration.","Avoid alcohol while taking this medicine.","Do not use with other NSAIDs or paracetamol-containing products.","Use with caution in elderly patients due to increased risk of side effects.","Use with caution in patients with asthma, as NSAIDs may trigger bronchospasm.","Monitor for signs of gastrointestinal bleeding, especially in patients with a history of ulcers.","Discontinue and consult a doctor if you experience symptoms of liver injury.","Do not use for more than 7 days without medical advice."]

🤱 Lactation Safety

Nimesulide may pass into breast milk. It is not recommended during breastfeeding due to potential risks to the infant. Paracetamol is considered safe during breastfeeding. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose of this medicine can cause severe liver damage due to paracetamol and gastrointestinal bleeding due to nimesulide. Symptoms of overdose may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding. Do not take other pain relievers or NSAIDs without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, liver or kidney disease, high blood pressure, or heart disease. Do not use this medicine during pregnancy, especially in the third trimester, unless specifically advised by your doctor. It may pass into breast milk; consult your doctor before breastfeeding. Store at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for safer alternatives for pain relief.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but should be used with caution due to risk of bleeding and kidney problems. Follow your surgeon's instructions.

🦷 Dental Procedures

This medicine can be used for dental pain, but inform your dentist if you are taking it before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods in your diet, such as fruits and vegetables.
🧘
Get adequate sleep to aid recovery.
🌞
Stay well hydrated throughout the day.

🏋️ Exercise Considerations

Avoid strenuous exercise while taking this medicine, especially if you have pain or inflammation. Gentle stretching and low-impact activities are recommended. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce intake of processed and fried foods.
Stay well hydrated by drinking plenty of water.
Avoid alcohol while taking this medicine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take breaks and stay hydrated.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your pain or fever persists beyond 3 days, or if you experience any serious side effects such as gastrointestinal bleeding, liver problems, or allergic reactions. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to increased risk of gastrointestinal bleeding, liver damage, kidney problems, and cardiovascular events. If long-term use is necessary, regular monitoring of liver and kidney function, and blood counts is advised. Consult your doctor for alternative treatments if pain persists.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Hot/cold therapy

Applying heat or cold packs can help reduce pain and inflammation.

Evidence: Well-established
Acupuncture

May provide pain relief for some individuals.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture and heat. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman with acute dental pain
Took this medicine for severe toothache. Pain relief was effective within 1 hour. She was advised to take it with food and not to exceed 2 tablets per day. She experienced mild nausea which resolved after taking with food.
💡 Lesson: Taking this medicine with food reduces gastrointestinal side effects and ensures better compliance.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30 minutes to 1 hour after taking this medicine.

Q: Can I take this medicine on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe to take this medicine with other pain relievers?

A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as it may increase the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine is safe for long-term use.
    Fact: This medicine is intended for short-term use only. Prolonged use can increase the risk of liver, kidney, and gastrointestinal problems.
  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset and the risk of ulcers.
  • Myth: This medicine is safe during pregnancy.
    Fact: It is generally avoided during pregnancy, especially in the third trimester, due to potential risks to the fetus.

🔄 Alternative Options

Generic Alternatives

  • Nimesulide + Paracetamol combination (generic)

Brand Alternatives

  • Nimuviz P 100mg/325mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Nimesulide + Paracetamol","class":"NSAID + Analgesic","uses":"Acute pain, fever","gi_risk":"Moderate","liver_risk":"Moderate"},{"medicine":"Ibuprofen + Paracetamol","class":"NSAID + Analgesic","uses":"Acute pain, fever","gi_risk":"Moderate","liver_risk":"Low"},{"medicine":"Diclofenac + Paracetamol","class":"NSAID + Analgesic","uses":"Acute pain, fever","gi_risk":"High","liver_risk":"Moderate"}]

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