Nimucide 100mg/325mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Yellowing of skin or eyes
- Dark urine or decreased urine output
- Difficulty breathing or swelling of face, lips, or throat
- Severe headache with visual changes
- Unusual bruising or bleeding
- Persistent fever or pain lasting more than 3 days
If experiencing severe symptoms, call emergency services immediately.
What is nimucide 100mg/325mg tablet used for?
This medicine is a combination of nimesulide and paracetamol used for short-term relief of acute pain, inflammation, and fever. It works by reducing prostaglandins that cause pain and swelling. It should be taken with food and not exceeding 3 tablets in 24 hours.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nimucide 100mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नाइमसुलाइड और पैरासिटामोल का संयोजन है, जिसका उपयोग तीव्र दर्द, सूजन और बुखार के अल्पकालिक उपचार के लिए किया जाता है। यह मांसपेशियों और जोड़ों के दर्द, दांत दर्द, सर्जरी के बाद के दर्द और मासिक धर्म के दर्द में राहत देती है। यह दवा सूजन पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। इसे भोजन के साथ लेना चाहिए और 24 घंटे में 3 गोलियों से अधिक नहीं लेना चाहिए। यह दवा 12 वर्ष से कम उम्र के बच्चों, गर्भवती महिलाओं और स्तनपान कराने वाली महिलाओं के लिए नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सीने में जलन, दस्त और चक्कर आना शामिल हैं। कुछ रोगियों को सिरदर्द, नींद आना या त्वचा पर दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें पेट या आंतों में रक्तस्राव, अल्सर, लीवर की क्षति, गुर्दे की समस्या और गंभीर एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको रक्तस्राव, आंखों या त्वचा का पीलापन, गहरे रंग का मूत्र या सांस लेने में कठिनाई हो, तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या उपचार की अवधि से अधिक न लें। पेट की परेशानी कम करने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे लीवर की क्षति और पेट में रक्तस्राव का खतरा बढ़ सकता है। पैरासिटामोल युक्त अन्य दर्द निवारक दवाएं बिना डॉक्टर की सलाह के न लें। यदि आपको पेट के अल्सर, गुर्दे या लीवर की बीमारी, अस्थमा या रक्तस्राव विकार का इतिहास है, तो अपने डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान इस दवा का उपयोग न करें।
💊 nimucide 100mg/325mg tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in muscles, joints, and soft tissues, such as in sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after minor surgeries.","evidence":"Moderate"},{"condition":"Fever","description":"Reduces fever due to its paracetamol component.","evidence":"Well-established"},{"condition":"Primary dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Osteoarthritis flare-ups","description":"May be used short-term for pain relief during flare-ups, but not for long-term management.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Musculoskeletal pain, Dental pain, Post-operative pain, Fever, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nimucide 100mg/325mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Nimesulide is a non-steroidal anti-inflammatory drug that selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts mainly in the central nervous system by inhibiting prostaglandin synthesis and modulating pain perception, and it also affects the hypothalamic heat-regulating center to reduce fever. Together, they provide rapid and effective relief from pain and inflammation.
Mechanism Steps
💡 How to Take nimucide 100mg/325mg tablet
Strength: Each tablet contains nimesulide 100 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally two to three times daily, preferably after meals. The maximum recommended daily dose is 3 tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose or duration of treatment. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not recommended for children under 12 years of age. Consult a pediatrician for appropriate pain relief options. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with mild to moderate renal impairment. Dose reduction may be necessary. This medicine is contraindicated in severe renal impairment (eGFR <30 mL/min). Consult a nephrologist or clinician for dose adjustment. |
| Hepatic Impairment | Use with caution in patients with mild to moderate hepatic impairment. Dose reduction and close monitoring of liver function are recommended. This medicine is contraindicated in severe hepatic impairment. Consult a hepatologist or clinician for dose adjustment. |
| Maximum Daily Dose | The maximum recommended daily dose is 3 tablets (nimesulide 300 mg and paracetamol 975 mg) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nimucide 100mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Major | |
| Furosemide | Moderate | |
| Lithium | Moderate | |
| SSRIs | Moderate | |
| Phenytoin | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, diclofenac)
- Corticosteroids
- Methotrexate
- ACE inhibitors and ARBs
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Lithium
- SSRIs
- Anticonvulsants (e.g., phenytoin, carbamazepine)
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage, especially from paracetamol, and can worsen gastrointestinal irritation and bleeding caused by nimesulide.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to nimesulide, paracetamol, or any component of the formulation.","Active peptic ulcer or history of recurrent ulcers.","Severe liver impairment or active liver disease.","Severe kidney impairment (eGFR
⚠️ Warnings & Precautions
["Take this medicine with food to reduce stomach upset.","Do not exceed the recommended dose or duration of treatment.","Avoid alcohol while taking this medicine.","Do not use other paracetamol-containing products concurrently.","Use with caution in elderly patients due to increased risk of side effects.","Consult your doctor if you have a history of stomach ulcers, kidney or liver disease, or asthma.","Stop the medicine and seek medical help if you experience signs of liver damage, bleeding, or allergic reaction.","Do not use for more than 5-7 days without medical advice.","This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor about all other medications you are taking."]
🤱 Lactation Safety
Nimesulide and paracetamol are excreted in breast milk. This medicine is not recommended during breastfeeding due to potential risks to the infant. Consult your doctor for alternative pain relief options.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage, especially due to paracetamol. Symptoms of overdose may include nausea, vomiting, abdominal pain, confusion, and jaundice. If you suspect an overdose, seek emergency medical attention immediately. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and gastrointestinal bleeding. Do not take other pain relievers or fever reducers containing paracetamol without consulting your doctor, as this can lead to overdose. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, asthma, or bleeding disorders. Do not use this medicine for more than 5-7 days unless directed by a doctor. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events with this medicine. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Avoid concurrent use with other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended for women planning pregnancy or during pregnancy, especially in the third trimester, due to potential risks to the fetus. Consult your doctor for safer pain relief options before conception.
🏥 Post-Surgery Considerations
This medicine may be used for short-term post-operative pain relief, but it can increase the risk of bleeding and interfere with wound healing. Consult your surgeon before taking this medicine after surgery.
🦷 Dental Procedures
This medicine can be used for short-term relief of dental pain, but it is not a substitute for dental treatment. Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you have musculoskeletal pain, gentle stretching and low-impact exercises may be beneficial, but consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take regular breaks and maintain good posture. If your job involves physical labor, consult your doctor about modifications.
🛑 When to Stop This Medicine
Stop taking this medicine if you experience any signs of a serious allergic reaction, gastrointestinal bleeding, liver problems, or if your pain persists beyond 5-7 days. Do not stop abruptly if you have been taking it for a longer duration without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to the risk of serious side effects such as gastrointestinal bleeding, liver damage, kidney impairment, and cardiovascular events. If long-term pain management is needed, consult your doctor for safer alternatives and regular monitoring of liver and kidney function.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and inflammation.
Evidence: ModerateMay provide pain relief for some individuals.
Evidence: LimitedMeditation, yoga, and deep breathing can help manage pain perception.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before receiving any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule accordingly, but do not exceed the maximum daily dose. Check the customs regulations of your destination country regarding prescription medications. Always carry enough supply for your trip and a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 minutes to 1 hour after taking it.
A: This medicine is intended for short-term use only, typically not more than 5-7 days. Consult your doctor if pain persists.
A: No, alcohol should be avoided while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding.
A: This medicine is not recommended for children under 12 years of age. Consult a pediatrician for alternative pain relief.
A: This medicine is not recommended during pregnancy, especially in the third trimester. Consult your doctor for safer alternatives.
A: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is safe for long-term use.
Fact: This medicine is intended for short-term use only. Long-term use can increase the risk of liver, kidney, and gastrointestinal problems. - Myth: It is safe to take this medicine with alcohol.
Fact: Alcohol should be avoided while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding. - Myth: This medicine can be given to children.
Fact: This medicine is not recommended for children under 12 years of age due to safety concerns. - Myth: More tablets mean faster relief.
Fact: Taking more than the recommended dose can lead to serious side effects and does not provide faster relief.
🔄 Alternative Options
Generic Alternatives
- Nimesulide 100 mg + Paracetamol 325 mg tablet
Brand Alternatives
- Nimucide 100mg/325mg tablet