Nimtyx P 100mg/325mg Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is nimtyx p 100mg/325mg tablet used for?
This medicine is a combination of nimodipine 100 mg and paracetamol 325 mg used to prevent cerebral vasospasm after subarachnoid hemorrhage and to relieve pain and fever. It is taken orally as directed by a doctor.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nimtyx p 100mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा निमोडिपिन 100 मिलीग्राम और पैरासिटामोल 325 मिलीग्राम का संयोजन है। इसका उपयोग सबराचनॉइड हैमरेज के बाद मस्तिष्क की रक्त वाहिकाओं में ऐंठन को रोकने और दर्द व बुखार को कम करने के लिए किया जाता है। यह मस्तिष्क में रक्त के प्रवाह को बेहतर बनाने में मदद करती है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर गर्मी लगना, जी मिचलाना और पेट में असहजता शामिल हैं। कुछ लोगों में रक्तचाप कम हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यकृत की क्षति के लक्षण जैसे पीलिया, गहरे रंग का मूत्र, या लगातार उल्टी हो सकती है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे पानी के साथ पूरा निगलें, चबाएं नहीं। भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। शराब का सेवन न करें। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आपको यकृत या गुर्दे की बीमारी है तो डॉक्टर को बताएं। गाड़ी चलाते समय सावधानी बरतें।
💊 nimtyx p 100mg/325mg tablet Uses & Benefits
- [{"condition":"Subarachnoid hemorrhage (prevention of vasospasm)","description":"Nimodipine is used to reduce the risk of delayed cerebral ischemia due to vasospasm after aneurysmal subarachnoid hemorrhage.
- Paracetamol may be included for pain and fever management.","evidence":"Well-established for nimodipine; paracetamol use is supportive."},{"condition":"Cerebrovascular disorders with associated pain or fever","description":"May be prescribed in certain cerebrovascular conditions where both vasospasm and pain/fever are present, though evidence for the combination is limited.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Nimodipine has been studied off-label for migraine prevention, but evidence is conflicting and it is not a first-line option.","evidence":"Limited"},{"condition":"Bipolar disorder","description":"Some small studies suggest nimodipine may have mood-stabilizing effects, but this is not an approved use.","evidence":"Limited"}]
Primary treatment for: Subarachnoid hemorrhage (prevention of vasospasm)
Also treats: Cerebrovascular disorders, Pain and fever associated with neurological conditions
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nimtyx p 100mg/325mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Nimodipine is a dihydropyridine calcium channel blocker that selectively inhibits calcium influx into vascular smooth muscle cells, with a preferential effect on cerebral arteries. By blocking L-type calcium channels, it causes relaxation of cerebral blood vessels, reducing vasospasm and improving cerebral blood flow. Paracetamol acts primarily in the central nervous system, where it inhibits prostaglandin synthesis, likely through interaction with the peroxidase site of cyclooxygenase enzymes. This results in analgesic and antipyretic effects without significant anti-inflammatory action. The combination provides both cerebrovascular benefit and symptomatic relief of pain and fever.
Mechanism Steps
💡 How to Take nimtyx p 100mg/325mg tablet
Strength: Each immediate-release tablet contains nimodipine 100 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally, typically every 8 to 12 hours, depending on the condition being treated. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to therapy. Do not self-adjust the dose. Follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of nimodipine. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for renal impairment, but caution is advised. Monitor renal function and adjust as needed under medical supervision. |
| Hepatic Impairment | In hepatic impairment, nimodipine clearance may be reduced, and paracetamol toxicity risk increases. Dose reduction and close monitoring are recommended. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose of paracetamol should not exceed 4 grams (4000 mg) from all sources. For nimodipine, the maximum daily dose is typically 360 mg, but this must be determined by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nimtyx p 100mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Rifampin | Major | |
| Warfarin | Major | |
| Amlodipine | Moderate | |
| Metoprolol | Moderate | |
| Grapefruit juice | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- Strong CYP3A4 inducers (e.g., rifampin, carbamazepine)
- Warfarin
⚡ Moderate Interactions
- Other antihypertensives
- Beta-blockers
- Grapefruit juice
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver damage from paracetamol and may enhance the blood pressure-lowering effect of nimodipine, leading to dizziness or fainting.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to nimodipine or paracetamol","Severe hepatic impairment","Severe hypotension","Concurrent use with strong CYP3A4 inhibitors","Pregnancy (unless clearly needed)"]
⚠️ Warnings & Precautions
["Avoid alcohol during treatment.","Do not exceed recommended dose of paracetamol.","Use caution in elderly patients.","Monitor blood pressure regularly.","Avoid grapefruit juice.","Inform doctor of all other medications."]
🤱 Lactation Safety
Nimodipine is excreted in breast milk and may affect the infant. Paracetamol is also excreted in breast milk but is generally considered compatible with breastfeeding. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose of this medicine can cause severe hypotension, bradycardia, and liver damage from paracetamol. Seek immediate medical attention. Treatment is supportive and may include activated charcoal, acetylcysteine for paracetamol toxicity, and intravenous fluids for hypotension.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Swallow the tablet whole with a glass of water; do not crush or chew it. It can be taken with or without food, but taking it with food may reduce stomach upset. Avoid alcohol while on this medicine, as it can increase the risk of liver damage and enhance the blood pressure-lowering effect. Inform your doctor about all other medicines you are taking, especially blood pressure medications, anticoagulants, and other pain relievers. Do not take other paracetamol-containing products simultaneously to avoid overdose. If you have liver or kidney disease, your doctor may need to adjust your dose. Use caution when driving or operating machinery until you know how this medicine affects you. Store at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood pressure-lowering effects of nimodipine and may require lower doses. Regular monitoring of blood pressure, heart rate, and renal function is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Nimodipine is not recommended during pregnancy unless clearly needed. Paracetamol should be used at the lowest effective dose for the shortest duration.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used to prevent vasospasm in certain neurosurgical procedures. Follow your surgeon's instructions regarding dosing and monitoring.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may affect blood pressure and bleeding risk. Your dentist may need to take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may cause dizziness or fainting until you know how this medicine affects you. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or low blood pressure, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Take breaks and stay hydrated if you have a physically demanding job.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your condition improves, your doctor will advise you on whether to continue or stop. Abrupt discontinuation may lead to rebound effects.
📅 Long-Term Use Effects
Long-term use of this medicine requires monitoring of liver and kidney function, blood pressure, and heart rate. Prolonged high-dose paracetamol can increase the risk of liver damage. Nimodipine may cause tolerance or cumulative hypotension. Regular follow-up with your doctor is essential to adjust the dose and detect any adverse effects early.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain management.
Evidence: Well-establishedMay help reduce stress and improve overall well-being.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule gradually under medical guidance. Check customs regulations for controlled substances.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Nimodipine starts working within 30-60 minutes, and paracetamol also begins to relieve pain and fever within 30-60 minutes.
A: Yes, you can take it with or without food, but taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any headache.
Fact: It is specifically for certain cerebrovascular conditions and should not be used for routine headaches without medical advice. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol increases the risk of liver damage and low blood pressure.
🔄 Alternative Options
Generic Alternatives
- Nimodipine 100 mg + Paracetamol 325 mg tablet (generic)
Brand Alternatives
- Nimtyx P 100mg/325mg Tablet