Nimpic 50mg Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes (jaundice)
- Dark urine or pale stools
- Severe abdominal pain or tenderness
- Black, tarry, or bloody stools
- Vomiting blood or material that looks like coffee grounds
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe skin rash with blisters or peeling
- Decreased urine output or swelling in the legs
- Unusual bleeding or bruising
- Severe headache with stiff neck or sensitivity to light
- Persistent fever or sore throat
If experiencing severe symptoms, call emergency services immediately.
What is nimpic 50mg syrup used for?
This medicine is a 50 mg per 5 mL oral syrup containing nimesulide, an NSAID used for short-term relief of acute pain and inflammation. It works by blocking COX-2 enzymes. It is contraindicated in children under 12, during pregnancy, and in patients with liver or kidney disease. Always take it with food and for the shortest duration possible.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nimpic 50mg syrup के बारे में (Hindi Summary)
उपयोग: यह दवा निमेसुलाइड (50 मिलीग्राम/5 मिलीलीटर) सिरप के रूप में उपलब्ध है, जो दर्द और सूजन को कम करने के लिए इस्तेमाल की जाती है। यह मुख्य रूप से जोड़ों के दर्द, मांसपेशियों की चोट, दांत दर्द, और ऑपरेशन के बाद के दर्द में राहत देने के लिए दी जाती है। यह दवा शरीर में प्रोस्टाग्लैंडिन नामक रसायन को कम करती है, जिससे दर्द और सूजन कम होती है। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे 7-10 दिन से ज्यादा नहीं लेना चाहिए। 12 साल से छोटे बच्चों, गर्भवती महिलाओं, और लिवर या किडनी की बीमारी वाले मरीजों को यह दवा नहीं दी जानी चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, चक्कर आना, और सिरदर्द शामिल हैं। कुछ मरीजों को त्वचा पर चकत्ते भी हो सकते हैं। गंभीर दुष्प्रभावों में लिवर की क्षति, पेट में रक्तस्राव, किडनी की समस्या, और गंभीर एलर्जी प्रतिक्रिया शामिल हैं। अगर आपको आंखों या त्वचा का पीला पड़ना, गहरे रंग का पेशाब, पेट में तेज दर्द, काला या खूनी दस्त, या चेहरे, होंठ या गले में सूजन दिखे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक या अवधि को न बढ़ाएं। इसे भोजन या दूध के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के साथ शराब न लें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ जाता है। अगर आपको पेट के अल्सर, लिवर या किडनी की गंभीर बीमारी, या निमेसुलाइड से एलर्जी है, तो यह दवा न लें। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। 7-10 दिन से ज्यादा इस दवा का इस्तेमाल न करें। इसे बच्चों की पहुंच से दूर रखें।
💊 nimpic 50mg syrup Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation associated with sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain following minor surgical procedures.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain after dental extraction.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Reduces pain and improves joint mobility in osteoarthritis, but only for short-term use.","evidence":"Established for short-term use"},{"condition":"Primary dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Fever","description":"Sometimes used to reduce fever, but not a first-line choice due to safety concerns.","evidence":"Limited"},{"condition":"Migraine","description":"Occasionally used for acute migraine attacks, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Osteoarthritis, Dysmenorrhea, Post-operative pain, Dental pain, Musculoskeletal injuries
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nimpic 50mg syrup |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's-Non-Selective COX 1&2 Inhibitors (Others) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. The World Health Organization has not issued specific guidelines for the use of nimesulide. Due to safety concerns, nimesulide is not approved in many countries, including the United States, Canada, and parts of Europe. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research has not issued specific guidelines for nimesulide. However, the Drug Controller General of India has restricted the use of nimesulide in children below 12 years and recommends short-term use only. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme, which is responsible for producing prostaglandins that mediate pain, inflammation, and fever. By blocking COX-2, it reduces the synthesis of these prostaglandins, thereby decreasing pain and swelling. Unlike non-selective NSAIDs, it has less effect on COX-1, which is why it may cause fewer gastrointestinal side effects, although the risk is not eliminated.
Mechanism Steps
💡 How to Take nimpic 50mg syrup
Strength: 50 mg per 5 mL oral syrup.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 50 mg to 100 mg (5 mL to 10 mL of the 50 mg/5 mL syrup) taken twice daily after meals. The maximum recommended daily dose is 200 mg. The duration of treatment should be as short as possible, typically not exceeding 7-10 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is contraindicated in children below 12 years of age due to the risk of serious liver injury. Consult a pediatrician for appropriate alternatives. |
| Elderly Dosage | Elderly patients (above 65 years) may be more susceptible to the adverse effects of this medicine, especially gastrointestinal bleeding, renal impairment, and liver toxicity. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | In patients with mild to moderate renal impairment (creatinine clearance 30-60 mL/min), no dose adjustment is usually necessary, but caution is advised. This medicine is contraindicated in patients with severe renal impairment (creatinine clearance <30 mL/min). Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | This medicine is contraindicated in patients with severe hepatic impairment. In patients with mild to moderate hepatic impairment, use with caution and at reduced doses. Dose must be individualized by a qualified clinician based on liver function tests. |
| Maximum Daily Dose | 200 mg per day. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nimpic 50mg syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Aspirin | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| SSRIs | Moderate | |
| Corticosteroids | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, diclofenac)
- Corticosteroids
- ACE inhibitors and ARBs
- Diuretics
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Antihypertensives (e.g., beta-blockers, calcium channel blockers)
- SSRIs
- Cyclosporine
- Tacrolimus
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine because it significantly increases the risk of gastrointestinal bleeding, ulceration, and liver damage. Both alcohol and nimesulide are metabolized by the liver, and their combined use can overwhelm the liver's detoxification pathways, leading to hepatotoxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to nimesulide or any other component of the formulation","History of nimesulide-induced hepatotoxicity","Active peptic ulcer disease or history of recurrent ulcers","Severe liver impairment","Severe kidney impairment (creatinine clearance
⚠️ Warnings & Precautions
["This medicine should be used for the shortest duration possible, usually not exceeding 7-10 days.","Do not exceed the recommended dose.","Take with food or milk to reduce gastrointestinal side effects.","Avoid alcohol while taking this medicine.","Inform your doctor if you have a history of liver or kidney disease, heart failure, hypertension, or gastrointestinal ulcers.","Stop the medicine and consult your doctor immediately if you experience symptoms of liver injury such as yellowing of eyes or skin, dark urine, or severe abdominal pain.","Use with caution in elderly patients due to increased risk of adverse effects.","Do not use in children under 12 years of age.","Avoid concurrent use with other NSAIDs, anticoagulants, or corticosteroids.","Monitor liver function if prolonged use is necessary."]
🤱 Lactation Safety
Not established from the available information. It is not known whether nimesulide is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, abdominal pain, drowsiness, and in severe cases, gastrointestinal bleeding, liver damage, and renal failure. There is no specific antidote. Treatment is supportive and symptomatic. If overdose is suspected, seek immediate medical attention. Activated charcoal may be administered if the patient presents within 1-2 hours of ingestion. Monitor liver and kidney function, and provide supportive care as needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding. Do not use this medicine if you have a history of stomach ulcers, bleeding disorders, severe liver or kidney disease, or if you are allergic to nimesulide or other NSAIDs. Inform your doctor about all other medicines you are taking, especially blood thinners, antihypertensives, and other NSAIDs. Do not use this medicine for more than 7-10 days without medical advice. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of adverse effects from this medicine, including gastrointestinal bleeding, renal impairment, and liver toxicity. Use with caution at the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly. Avoid concurrent use with other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester, due to the risk of premature closure of the ductus arteriosus and other complications. If you are planning pregnancy or are pregnant, consult your doctor for safer alternatives. Do not take this medicine without medical advice.
🏥 Post-Surgery Considerations
This medicine may be used for short-term post-operative pain management, but it should be used with caution due to the risk of bleeding and renal impairment. Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped before certain procedures.
🦷 Dental Procedures
If you are scheduled for dental work, inform your dentist that you are taking this medicine. It may increase the risk of bleeding during dental procedures. Your dentist may advise you to stop the medicine temporarily before the procedure. Do not stop without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require mental alertness until you know how the medicine affects you. If you have pain, gentle stretching and low-impact exercises may be beneficial, but consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take regular breaks and maintain good posture. Inform your employer if you need to take this medicine during work hours.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience any signs of liver injury (yellowing of eyes or skin, dark urine, severe abdominal pain), gastrointestinal bleeding (black or bloody stools, vomiting blood), allergic reactions (rash, swelling, difficulty breathing), or if your pain does not improve within 7-10 days. Do not stop abruptly if you are on a prescribed course without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to the risk of serious adverse effects, including hepatotoxicity, nephrotoxicity, and gastrointestinal bleeding. Prolonged use can lead to liver damage, kidney impairment, and increased cardiovascular risk. If long-term use is unavoidable, regular monitoring of liver and kidney function is essential. The medicine should be discontinued if any signs of liver injury or renal impairment appear.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help manage chronic pain and improve mobility without medication.
Evidence: Well-establishedA safer alternative for mild to moderate pain, especially for short-term use.
Evidence: Well-establishedAnother NSAID that may be used as an alternative, but with similar gastrointestinal risks.
Evidence: Well-establishedCreams or gels containing diclofenac or capsaicin can provide localized pain relief with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a vaccine, inform your healthcare provider that you are taking this medicine. It is generally safe to continue, but your doctor may advise temporary discontinuation if you have an active infection or fever.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep the bottle tightly closed
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially if traveling internationally. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust the dosing schedule gradually, but do not take extra doses. Keep it in your carry-on luggage to avoid temperature extremes in checked baggage. Check local customs regulations regarding prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It should only be used for short-term relief, typically not exceeding 7-10 days, unless otherwise directed by your doctor.
A: No, alcohol should be strictly avoided while taking this medicine as it increases the risk of gastrointestinal bleeding and liver damage.
A: No, this medicine is contraindicated in children below 12 years of age due to the risk of serious liver injury.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: Nimesulide is completely safe for children.
Fact: Nimesulide is contraindicated in children below 12 years due to the risk of serious liver injury. - Myth: Nimesulide can be taken for long periods without any risk.
Fact: Nimesulide should only be used for short-term relief (up to 7-10 days) because of the risk of liver and kidney damage. - Myth: Nimesulide is safe to take with alcohol.
Fact: Alcohol increases the risk of gastrointestinal bleeding and liver toxicity when taken with nimesulide. - Myth: Nimesulide is approved worldwide.
Fact: Nimesulide is not approved in many countries, including the US, Canada, and parts of Europe, due to safety concerns.
🔄 Alternative Options
Generic Alternatives
- Nimesulide 50 mg/5 mL oral suspension
Brand Alternatives
- Nise
- Nimulid
- Nimesulide
- Nimsaid
- Nimodol