Nimlen P 100mg/325mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Fainting or severe dizziness
If experiencing severe symptoms, call emergency services immediately.
What is nimlen p 100mg/325mg tablet used for?
This medicine is a combination of nimodipine 100 mg and paracetamol 325 mg. It is used to prevent cerebral vasospasm after subarachnoid hemorrhage and to manage mild to moderate pain and fever. It should only be taken under a doctor's supervision.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nimlen p 100mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा निमोडिपिन 100 मिलीग्राम और पैरासिटामोल 325 मिलीग्राम का संयोजन है। इसका उपयोग सबराचनॉइड रक्तस्राव के बाद मस्तिष्क की रक्त वाहिकाओं में ऐंठन (वासोस्पास्म) को रोकने के लिए किया जाता है। साथ ही यह हल्के से मध्यम दर्द और बुखार में राहत देने में मदद करती है। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए। इसे सामान्य सिरदर्द या बुखार के लिए अपने आप न लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर गर्मी लगना, जी मिचलाना और पेट में असहजता शामिल हैं। कुछ लोगों में रक्तचाप कम हो सकता है, जिससे चक्कर आना या बेहोशी हो सकती है। पैरासिटामोल की अधिक मात्रा से लिवर को नुकसान हो सकता है। अगर आंखों या त्वचा का रंग पीला पड़े, गहरे रंग का पेशाब आए, या लगातार उल्टी हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। इस दवा के साथ शराब बिल्कुल न लें, क्योंकि इससे लिवर को नुकसान और चक्कर आने की समस्या बढ़ सकती है। पैरासिटामोल वाली कोई अन्य दवा साथ में न लें। डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। जब तक पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। नियमित रूप से रक्तचाप और लिवर की जांच कराते रहें।
💊 nimlen p 100mg/325mg tablet Uses & Benefits
- [{"condition":"Prevention of cerebral vasospasm after subarachnoid hemorrhage","description":"Nimodipine is used to reduce the risk of delayed ischemic neurological deficits caused by vasospasm following a subarachnoid hemorrhage.
- Paracetamol may be included for pain and fever management in these patients.","evidence":"Well-established for nimodipine component"},{"condition":"Management of acute pain and fever in neurological settings","description":"The paracetamol component provides relief from mild to moderate pain and reduces fever, which can be useful in post-neurosurgical or neurocritical care settings.","evidence":"Well-established for paracetamol component"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Nimodipine has been studied in some small trials for preventing migraines, but evidence is limited and it is not a standard first-line treatment.","evidence":"Limited"},{"condition":"Bipolar disorder adjunct","description":"Some research suggests nimodipine may have mood-stabilizing effects, but this is not an approved use and requires specialist supervision.","evidence":"Limited"}]
Primary treatment for: Cerebral vasospasm prevention after subarachnoid hemorrhage
Also treats: Pain management, Fever management
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nimlen p 100mg/325mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise stated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Nimodipine is a dihydropyridine calcium channel blocker that selectively inhibits the influx of extracellular calcium ions into vascular smooth muscle cells, with a preferential effect on cerebral arteries. This leads to relaxation of cerebral blood vessels, reducing vasospasm and improving cerebral blood flow. Paracetamol works primarily in the central nervous system by inhibiting prostaglandin synthesis, which raises the pain threshold and helps reset the hypothalamic thermostat to reduce fever. The combination provides both cerebrovascular protection and symptomatic relief of pain and fever.
Mechanism Steps
💡 How to Take nimlen p 100mg/325mg tablet
Strength: Each tablet contains nimodipine 100 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally, typically every 6 to 8 hours as prescribed by your doctor. The exact dose and frequency depend on the condition being treated, your response to therapy, and your kidney and liver function. Do not self-adjust the dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of nimodipine and the central nervous system effects of paracetamol. Start with a lower dose and monitor blood pressure and liver function closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for mild to moderate renal impairment. In severe renal impairment, use with caution and monitor closely. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | Avoid use in severe hepatic impairment. In mild to moderate hepatic impairment, reduce the dose and monitor liver function tests regularly. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose of paracetamol from all sources should not exceed 4000 mg for adults. The maximum daily dose of nimodipine should not exceed 360 mg, but the exact limit depends on the prescribed regimen. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nimlen p 100mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Amlodipine | Moderate | |
| Metoprolol | Moderate | |
| Carbamazepine | Major | |
| Clarithromycin | Major | |
| Phenytoin | Moderate | |
| Cimetidine | Moderate | |
| Grapefruit juice | Moderate |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine)
- Warfarin
⚡ Moderate Interactions
- Other antihypertensives
- Beta-blockers
- Alcohol
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. It increases the risk of liver damage from the paracetamol component and can worsen nimodipine-related dizziness and low blood pressure. Chronic alcohol use also lowers the threshold for paracetamol-induced liver injury.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to nimodipine, paracetamol, or any component of the tablet","Severe hepatic impairment or active liver disease","Severe hypotension or shock","Concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) without dose adjustment","Pregnancy and lactation unless clearly needed and prescribed by a doctor"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose of paracetamol; the maximum daily dose from all sources should not exceed 4 grams for adults.","Avoid alcohol completely while taking this medicine.","Use with caution in patients with liver or kidney disease.","May cause dizziness or low blood pressure; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are taking any other medications, especially blood pressure medicines, blood thinners, or seizure medicines.","Do not use for routine pain or fever without a doctor's advice."]
🤱 Lactation Safety
Nimodipine is excreted in breast milk in small amounts, and paracetamol also passes into breast milk. Consult your doctor before breastfeeding while taking this medicine. The benefits of breastfeeding should be weighed against the potential risks to the infant.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to paracetamol and profound hypotension due to nimodipine. Seek emergency medical attention immediately. Treatment includes activated charcoal if within 1-2 hours, N-acetylcysteine for paracetamol toxicity, and supportive care for hypotension. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet unless your doctor advises otherwise. Swallow it whole with a glass of water. Avoid alcohol completely while taking this medicine, as it can increase the risk of liver damage from paracetamol and worsen nimodipine-related dizziness. Do not take any other product containing paracetamol while on this medicine, as the combined dose can exceed safe limits. Inform your doctor about all other medicines you are taking, especially blood pressure medications, blood thinners, and seizure medicines. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep all follow-up appointments and get your blood pressure and liver function checked as advised. Store this medicine in its original container, away from moisture and direct sunlight, and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood pressure-lowering effects of nimodipine and may experience more dizziness or falls. Start with a lower dose and monitor blood pressure regularly. Liver and kidney function should also be checked periodically.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Nimodipine is not recommended during pregnancy unless clearly needed. Paracetamol is generally considered safe in pregnancy, but the combination should only be used if prescribed by a doctor.
🏥 Post-Surgery Considerations
This medicine may be prescribed after neurosurgery to prevent cerebral vasospasm and manage pain. Follow your surgeon's instructions carefully regarding dosing and activity restrictions. Report any unusual symptoms to your healthcare team immediately.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. The paracetamol component may interact with other painkillers used during dental work, and nimodipine can affect blood pressure. Your dentist may need to adjust medications accordingly.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting until your doctor says it is safe, especially if you have recently had a subarachnoid hemorrhage or surgery. Light walking and gentle stretching may be beneficial, but always follow your doctor's advice.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or low blood pressure, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Discuss with your doctor about when you can safely return to work, especially if your job involves physical labor or operating heavy equipment.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will decide when it is safe to stop based on your condition and response to treatment. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine should be under regular medical supervision. Prolonged use of paracetamol at high doses can increase the risk of liver and kidney problems. Nimodipine may cause persistent low blood pressure or dizziness. Regular monitoring of liver and kidney function, as well as blood pressure, is recommended. Do not continue this medicine beyond the prescribed duration without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedMay help manage stress and improve overall well-being.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for any vaccination, inform your healthcare provider that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip and check customs regulations for controlled or prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Nimodipine starts working within 30-60 minutes, and paracetamol also begins to relieve pain and fever within 30-60 minutes.
A: No, this medicine is not a general headache remedy. It is specifically prescribed for cerebral vasospasm prevention and should only be used under a doctor's supervision.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol should be completely avoided as it increases the risk of liver damage and severe dizziness.
A: Do not take any other paracetamol-containing products without consulting your doctor, as this can lead to liver damage.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is a general painkiller.
Fact: This medicine is not a general painkiller. It is specifically used for cerebral vasospasm prevention and should only be taken as prescribed. - Myth: It is safe to take extra doses if pain is severe.
Fact: Taking extra doses can lead to dangerous drops in blood pressure and liver damage from paracetamol. Never exceed the prescribed dose. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol should be completely avoided as it increases the risk of liver damage and severe dizziness.
🔄 Alternative Options
Generic Alternatives
- Nimodipine 100 mg + Paracetamol 325 mg tablet (generic)
Brand Alternatives
- Nimlen P 100mg/325mg Tablet