Nimdec P 100mg/325mg Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Yellowing of skin or eyes
- Decreased urine output
- Severe headache with visual changes
- Swelling of face, lips, or throat
- Difficulty breathing
If experiencing severe symptoms, call emergency services immediately.
What is nimdec p 100mg/325mg tablet used for?
This medicine is a combination of nimesulide and paracetamol used for short-term relief of acute pain and inflammation. It works by reducing pain and swelling. It should be taken with food and not for more than 5-7 days without medical advice.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nimdec p 100mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नाइमसुलाइड और पैरासिटामोल का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, सर्जरी के बाद के दर्द, और गठिया के दर्द में राहत देती है। यह दवा केवल अल्पकालिक उपयोग के लिए है और इसे डॉक्टर की सलाह के बिना 5-7 दिनों से अधिक नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, चक्कर आना और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में पेट में अल्सर या रक्तस्राव, लिवर की क्षति, गुर्दे की समस्या, और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकते हैं। यदि आपको काला मल, उल्टी में खून, पीलिया, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की जलन कम हो। शराब का सेवन न करें क्योंकि इससे लिवर और पेट की समस्या बढ़ सकती है। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आपको पेट अल्सर, लिवर या किडनी की बीमारी है, तो डॉक्टर को बताएं। 5-7 दिनों से अधिक इसका उपयोग न करें।
💊 nimdec p 100mg/325mg tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and low back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after minor surgeries.","evidence":"Moderate"},{"condition":"Osteoarthritis","description":"Reduces pain and improves joint function in osteoarthritis, but only for short-term use.","evidence":"Moderate"},{"condition":"Primary dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Fever","description":"Sometimes used to reduce fever due to the paracetamol component, but not a primary indication.","evidence":"Limited"},{"condition":"Migraine","description":"May be used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Musculoskeletal pain, Dental pain, Post-operative pain, Osteoarthritis, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nimdec p 100mg/325mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Nimesulide is a non-steroidal anti-inflammatory drug that selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, leading to pain relief and fever reduction. Together, they provide effective analgesia and anti-inflammatory action.
Mechanism Steps
💡 How to Take nimdec p 100mg/325mg tablet
Strength: Each tablet contains nimesulide 100 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally 1-2 times daily, as prescribed by your doctor. The dose depends on the severity of pain and your medical condition. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. The maximum duration of use without medical advice is 5-7 days. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 2 tablets (nimesulide 200 mg and paracetamol 650 mg) in divided doses. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nimdec p 100mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- Methotrexate
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Corticosteroids
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage, especially from paracetamol, and can increase the risk of stomach bleeding from nimesulide.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or history of recurrent ulcers","Severe liver disease","Severe kidney disease","Heart failure","Allergy to nimesulide, paracetamol, or other NSAIDs","Children under 12 years","Pregnancy (especially third trimester)","Breastfeeding"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose or duration.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients.","Inform your doctor if you have asthma, kidney or liver disease, or bleeding disorders.","Do not take other paracetamol-containing products concurrently.","Stop and consult a doctor if you experience signs of liver or kidney problems."]
🤱 Lactation Safety
Not established from the available information. This medicine may pass into breast milk. Consult your doctor before use during breastfeeding.
💊 Overdose Management
Overdose can cause severe liver damage, especially due to paracetamol. Symptoms may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and stomach bleeding. Do not take other medicines containing paracetamol or other NSAIDs without consulting your doctor. If you have a history of stomach ulcers, kidney or liver disease, asthma, or bleeding disorders, inform your doctor before taking this medicine. Do not use this medicine for more than 5-7 days unless directed by a doctor. If your pain persists or worsens, consult your doctor. Pregnant women, especially in the third trimester, and breastfeeding mothers should avoid this medicine unless clearly advised by a doctor. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of side effects, especially gastrointestinal bleeding and kidney problems. Use with caution and at the lowest effective dose for the shortest duration.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy planning or pregnancy. Consult your doctor for alternative pain relief options.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain, but only under medical supervision. Inform your surgeon about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine, especially if you have pain or inflammation. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe for office work.
🛑 When to Stop This Medicine
Stop taking this medicine if you experience any serious side effects such as stomach bleeding, liver problems, or allergic reactions. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of liver damage, kidney problems, and gastrointestinal bleeding. It should only be used for short-term relief. Regular monitoring of liver and kidney function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help reduce inflammation and pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, consult your doctor before vaccination if you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30-60 minutes after taking it.
A: It is best taken with food or milk to reduce stomach upset.
A: It is not recommended during pregnancy, especially in the third trimester, unless advised by a doctor.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is safe for long-term use.
Fact: This medicine is only for short-term use. Prolonged use can cause liver and kidney damage. - Myth: It is safe to take with other painkillers.
Fact: Taking with other NSAIDs or paracetamol can increase the risk of side effects.
🔄 Alternative Options
Generic Alternatives
- Nimesulide + Paracetamol generic tablets
Brand Alternatives
- Nimdec P 100mg/325mg Tablet