Nigest 200mg Tablet Sr: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden severe headache or visual changes
- Chest pain or difficulty breathing
- Swelling or pain in the legs
- Yellowing of skin or eyes
- Severe abdominal pain
- Unusual vaginal bleeding that is heavy or persistent
- Signs of allergic reaction such as rash, itching, or swelling of face or throat
If experiencing severe symptoms, call emergency services immediately.
What is nigest 200mg tablet sr used for?
This medicine is a synthetic progestogen used to treat abnormal uterine bleeding, endometriosis, and as part of hormone replacement therapy. It works by stabilizing the endometrium and suppressing ovulation.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nigest 200mg tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा एक सिंथेटिक प्रोजेस्टोजेन है जिसका उपयोग असामान्य गर्भाशय रक्तस्राव, एंडोमेट्रियोसिस और हार्मोन रिप्लेसमेंट थेरेपी में किया जाता है। यह गर्भाशय की परत को स्थिर करके रक्तस्राव को नियंत्रित करती है और ओव्यूलेशन को दबाती है। इसका उपयोग केवल डॉक्टर की सलाह पर ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में अनियमित योनि रक्तस्राव, स्तन में कोमलता, मतली, सिरदर्द, चक्कर आना और मूड में बदलाव शामिल हैं। गंभीर दुष्प्रभावों में रक्त के थक्के बनना, दृष्टि में गड़बड़ी और पीलिया शामिल हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। शराब का सेवन न करें। यदि आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं तो इसका उपयोग न करें। नियमित जांच के लिए डॉक्टर के पास जाएं।
💊 nigest 200mg tablet sr Uses & Benefits
[{"condition":"Abnormal uterine bleeding","description":"This medicine is used to control heavy or irregular menstrual bleeding by stabilizing the endometrium.","evidence":"Well-established"},{"condition":"Endometriosis","description":"It helps suppress endometrial tissue growth and relieve associated pain.","evidence":"Well-established"},{"condition":"Hormone replacement therapy","description":"Used in combination with estrogen to protect the endometrium in postmenopausal women.","evidence":"Well-established"},{"condition":"Palliative treatment of hormone-sensitive breast cancer","description":"May be used in selected cases to manage advanced breast cancer.","evidence":"Limited"},{"condition":"Prevention of endometrial hyperplasia","description":"Prescribed to reduce the risk of endometrial overgrowth in women taking estrogen alone.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Catamenial epilepsy","description":"Sometimes prescribed off-label to reduce seizure frequency related to menstrual cycles.","evidence":"Limited"},{"condition":"Premenstrual syndrome","description":"May be used off-label for severe premenstrual symptoms.","evidence":"Limited"}]
Primary treatment for: Abnormal uterine bleeding
Also treats: Endometriosis, Hormone replacement therapy, Breast cancer (palliative)
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nigest 200mg tablet sr |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Natural Progesterone |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a synthetic progestogen that binds to progesterone receptors in the endometrium, pituitary, and hypothalamus. By binding to these receptors, it transforms the endometrium from a proliferative to a secretory state, which helps control abnormal bleeding. It also suppresses gonadotropin release, thereby inhibiting ovulation and reducing endogenous estrogen production. Additionally, it has mild androgenic and anti-estrogenic effects, which contribute to its therapeutic actions in conditions like endometriosis.
Mechanism Steps
💡 How to Take nigest 200mg tablet sr
Strength: Sustained-release tablet, 200 mg
Dosage Information
| Adult Dosage | The adult dosage of this medicine varies depending on the condition being treated. For abnormal uterine bleeding, a common dose is 200 mg once daily for a specified duration. For endometriosis, the dose may be 200 mg once daily for several months. For hormone replacement therapy, the dose is typically lower and individualized. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects such as fluid retention and thromboembolic events. Use with caution and monitor closely. Dose adjustment may be necessary based on renal and hepatic function. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Use with caution and monitor renal function. |
| Hepatic Impairment | This medicine is contraindicated in severe liver disease. In mild to moderate hepatic impairment, dose adjustment may be necessary. Consult a clinician. |
| Maximum Daily Dose | The maximum daily dose of this medicine is 200 mg, but this may vary based on the indication. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nigest 200mg tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Rifampicin | Major | |
| Carbamazepine | Moderate | |
| St. John's wort | Moderate | |
| Grapefruit juice | Moderate |
🚨 Major Interactions
- Warfarin
- Rifampicin
⚡ Moderate Interactions
- Carbamazepine
- St. John's wort
🍷 Alcohol Interaction
Alcohol may increase the risk of liver toxicity and worsen side effects such as dizziness and drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known or suspected pregnancy","Undiagnosed vaginal bleeding","History of thromboembolic disorders","Severe liver disease","Known hypersensitivity to progestogens","Breast cancer (unless used for palliative care)"]
⚠️ Warnings & Precautions
["Use with caution in patients with a history of blood clots.","May cause fluid retention; caution in patients with heart or kidney disease.","May affect glucose tolerance; monitor blood sugar in diabetic patients.","May cause mood changes; caution in patients with depression.","Regular monitoring of liver function is advised during long-term use."]
🤱 Lactation Safety
This medicine is excreted in breast milk and may affect the nursing infant. It is generally not recommended during breastfeeding unless the benefits outweigh the risks. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, and withdrawal bleeding. There is no specific antidote. Treatment is symptomatic and supportive. In case of overdose, seek immediate medical attention.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
This medicine should only be taken exactly as prescribed by a qualified clinician. Do not adjust the dose or stop the medicine without consulting your doctor. Take the tablet at the same time each day, preferably with food to reduce stomach upset. Swallow the sustained-release tablet whole; do not crush, chew, or break it, as this can release the entire dose at once and increase the risk of side effects. Avoid alcohol while taking this medicine, as it may increase the risk of liver problems and worsen side effects such as dizziness. Inform your doctor if you have a history of blood clots, liver disease, migraine, or breast cancer. Use effective non-hormonal contraception if you are sexually active and not planning pregnancy, as this medicine is not a contraceptive and may cause harm to a fetus if pregnancy occurs. Regular follow-up visits and monitoring tests, such as liver function tests and blood pressure checks, are important. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more prone to fluid retention and thromboembolic events. Use with caution and monitor closely. Dose adjustment may be necessary based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. If you are planning to become pregnant, stop this medicine and consult your doctor for alternative treatments. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery due to the risk of thromboembolism. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. No specific precautions are established, but your dentist may consult your doctor if you have risk factors for bleeding.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue in some individuals. Avoid strenuous exercise if you feel unsteady. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or mood changes that could affect your ability to drive or operate machinery. Avoid these activities if you are affected. Discuss with your employer if you need accommodations.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as blood clots, severe headache, or visual disturbances, seek immediate medical attention and follow your doctor's advice on stopping.
📅 Long-Term Use Effects
Long-term use of this medicine may be associated with a small increased risk of breast cancer, liver problems, and thromboembolic events. Regular monitoring of liver function, blood pressure, and lipid profile is advised. Discuss the risks and benefits with your doctor periodically.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Options like tranexamic acid or NSAIDs may be used for heavy bleeding.
Evidence: Well-establishedFor severe cases, procedures like endometrial ablation or hysterectomy may be considered.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your doctor about all medications before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, continue taking the medicine at the same interval as prescribed; consult your doctor for specific advice. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: For control of uterine bleeding, effects may be seen within 24 to 48 hours. For endometriosis, it may take several weeks to months for full benefit.
A: No, this medicine is contraindicated in pregnancy as it may harm the fetus.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is a contraceptive.
Fact: This medicine is not a contraceptive and should not be used for birth control. - Myth: This medicine can be taken without a prescription.
Fact: This medicine requires a prescription and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Norethisterone acetate 200 mg sustained-release tablets
Brand Alternatives
- Nigest 200 mg tablet SR