Affocal-CT Softgel: Complete Guide to Uses, Dosage, and Safety
When to Call Your Doctor IMMEDIATELY
- Severe nausea, vomiting, or abdominal pain
- Confusion or altered mental status
- Irregular heartbeat or palpitations
- Decreased urine output or blood in urine
- Severe bone pain or muscle weakness
- Swelling of face, lips, or throat
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is nidcal cl tablet used for?
This medicine is a combination of calcitriol and calcium carbonate used to treat and prevent calcium and vitamin D deficiency, osteoporosis, and related bone disorders. It works by increasing calcium absorption and promoting healthy bone formation.
- Generic Name: Calcitriol (0.25mcg) + Calcium Carbonate (500mg)
- Manufacturer: Olcare Laboratories
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nidcal cl tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कैल्सिट्रियोल और कैल्शियम कार्बोनेट का संयोजन है, जिसका उपयोग हड्डियों की कमजोरी, ऑस्टियोपोरोसिस, रिकेट्स, ऑस्टियोमलेशिया और कैल्शियम की कमी के इलाज में किया जाता है। यह शरीर में कैल्शियम के अवशोषण को बढ़ाती है और हड्डियों को मजबूत बनाती है। यह दवा डॉक्टर के परामर्श से ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, कब्ज, पेट में गड़बड़ी और मुँह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर रक्त में कैल्शियम का स्तर बहुत अधिक हो जाए तो भ्रम, कमजोरी, अनियमित दिल की धड़कन और गुर्दे की पथरी हो सकती है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि अवशोषण बेहतर हो और पेट की परेशानी कम हो। पर्याप्त पानी पिएं। कैल्शियम और विटामिन डी की अन्य गोलियाँ बिना डॉक्टर की सलाह के न लें। नियमित रूप से रक्त में कैल्शियम और गुर्दे की जाँच कराते रहें। गर्भवती या स्तनपान कराने वाली महिलाएँ डॉक्टर से सलाह लें।
💊 nidcal cl tablet Uses & Benefits
[{"condition":"Osteoporosis","description":"Helps maintain bone mineral density and reduces fracture risk when combined with adequate calcium intake.","evidence":"Well-established"},{"condition":"Osteomalacia","description":"Treats softening of bones due to defective bone mineralization, often caused by vitamin D deficiency.","evidence":"Well-established"},{"condition":"Rickets","description":"Used in children to correct defective bone growth caused by vitamin D deficiency.","evidence":"Well-established"},{"condition":"Hypocalcemia","description":"Corrects low blood calcium levels, especially in chronic kidney disease and hypoparathyroidism.","evidence":"Well-established"},{"condition":"Chronic kidney disease-related bone disease","description":"Helps manage secondary hyperparathyroidism and renal osteodystrophy.","evidence":"Well-established"},{"condition":"Hypoparathyroidism","description":"Used to maintain normal calcium levels when parathyroid hormone is deficient.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Psoriasis","description":"Topical calcitriol is used for psoriasis, but oral use is not standard.","evidence":"Limited"},{"condition":"Prevention of corticosteroid-induced osteoporosis","description":"Sometimes prescribed along with steroids to protect bone health.","evidence":"Moderate"}]
Primary treatment for: Osteoporosis
Also treats: Osteomalacia, Rickets, Hypocalcemia, Chronic kidney disease-related bone disease, Hypoparathyroidism
📋 Drug Information
| Generic Name(s) | Calcitriol (0.25mcg) + Calcium Carbonate (500mg) |
| Brand Name | nidcal cl tablet |
| Manufacturer | Olcare Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines calcitriol, the active form of vitamin D3, with calcium carbonate. Calcitriol binds to vitamin D receptors in the intestine, bone, kidney, and parathyroid glands. In the intestine, it increases the production of calcium-binding proteins, which enhances calcium absorption from food. In the kidney, it reduces calcium excretion and increases phosphate reabsorption. In bone, it helps regulate bone remodeling by promoting normal mineralization. Calcium carbonate provides elemental calcium, which is essential for bone formation and various cellular functions. Together, they correct calcium and vitamin D deficiency and support healthy bone metabolism.
Mechanism Steps
💡 How to Take nidcal cl tablet
Strength: Calcitriol 0.25 mcg + Calcium Carbonate 500 mg softgel capsule
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one softgel capsule once daily or as directed by your doctor. The dose may be adjusted based on your serum calcium levels, kidney function, and the condition being treated. It is important to take this medicine with food to enhance absorption and reduce stomach upset. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of calcitriol and calcium. Start with a lower dose and monitor serum calcium levels closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary based on creatinine clearance and serum calcium levels. Regular monitoring is required. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and monitor liver function and calcium levels. |
| Maximum Daily Dose | The maximum daily dose should not exceed one softgel capsule unless specifically prescribed by a doctor. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nidcal cl tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Thiazide diuretics | Major | |
| Digoxin | Major | |
| Calcium supplements | Major | |
| Corticosteroids | Moderate | |
| Orlistat | Moderate | |
| Cholestyramine | Moderate | |
| Aluminum-containing antacids | Minor | |
| Iron supplements | Minor | |
| Phenytoin | Moderate | |
| Ketoconazole | Moderate |
🚨 Major Interactions
- Thiazide diuretics
- Digoxin
- Calcium supplements
⚡ Moderate Interactions
- Corticosteroids
- Orlistat
- Cholestyramine
🍷 Alcohol Interaction
Alcohol may impair calcium absorption and bone health. It is advisable to limit or avoid alcohol while taking this medicine, as it can counteract the beneficial effects on bones and increase the risk of falls and fractures.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypercalcemia","Hypercalciuria","History of calcium-containing kidney stones","Severe renal impairment","Hypersensitivity to calcitriol or calcium carbonate","Sarcoidosis","Hypervitaminosis D"]
⚠️ Warnings & Precautions
["Monitor serum calcium and phosphate regularly.","Avoid concurrent use with other calcium or vitamin D supplements unless prescribed.","Use with caution in patients with kidney disease or kidney stones.","Advise patients to maintain adequate fluid intake.","Avoid in patients with hypercalcemia or hypercalciuria.","Use with caution in patients with heart disease, especially those on digoxin.","Not recommended for children without specialist supervision.","Elderly patients may be more sensitive to hypercalcemia."]
🤱 Lactation Safety
Calcitriol is excreted in human milk. Calcium is also present in breast milk. The amount in breast milk is not sufficient to cause adverse effects in the infant, but the mother should consult her doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose can cause hypercalcemia, hypercalciuria, and potentially cardiac arrhythmias. Treatment includes discontinuation of the medicine, hydration, and monitoring of serum calcium and electrolytes. In severe cases, hospitalization and treatment with intravenous fluids, diuretics, or corticosteroids may be required. Seek immediate medical attention if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose on your own. Swallow the softgel capsule whole with a glass of water, preferably with a meal to improve absorption and reduce stomach upset. Avoid taking this medicine with large amounts of dairy products or calcium-fortified foods unless your doctor approves, as this can raise calcium levels too high. Drink plenty of water throughout the day to help prevent kidney stones. Your doctor may ask for regular blood tests to check calcium, phosphate, and kidney function. Inform your doctor if you have a history of kidney stones, heart disease, or sarcoidosis. Do not take antacids or other calcium supplements without consulting your doctor. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before using this medicine. Keep this medicine out of reach of children. Store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to hypercalcemia and kidney impairment. Start with a lower dose and monitor calcium levels frequently. Ensure adequate hydration and fall prevention strategies.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Adequate calcium and vitamin D are important for fetal bone development, but doses must be carefully managed to avoid hypercalcemia.
🏥 Post-Surgery Considerations
After surgery, especially orthopedic surgery, this medicine may be prescribed to support bone healing. Follow your surgeon's instructions regarding dosage and monitoring. Inform your surgeon about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, especially before dental surgery, as it may affect bone healing and calcium levels. No specific precautions are usually needed, but monitoring may be advised.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Weight-bearing exercises are beneficial for bone health, but avoid high-impact activities if you have osteoporosis or are at risk of fractures. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is generally safe to take while working. It does not usually cause drowsiness or impair driving. However, if you experience dizziness or confusion due to high calcium levels, avoid driving or operating heavy machinery and consult your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your calcium levels become too high, your doctor may advise you to stop or adjust the dose. Always follow medical guidance.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of serum calcium, phosphate, and kidney function. Prolonged hypercalcemia can lead to kidney stones, nephrocalcinosis, and soft tissue calcification. It is important to follow up with your doctor periodically to adjust the dose and prevent complications.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing intake of calcium-rich foods and safe sun exposure can help maintain bone health.
Evidence: Well-establishedRegular physical activity helps strengthen bones and improve balance.
Evidence: Well-establishedAlfacalcidol or cholecalciferol may be used as alternatives based on individual needs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, maintain your regular vaccination schedule, especially for influenza and pneumonia, as respiratory infections can affect bone health and overall well-being.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust the timing of your dose gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Calcitriol starts working within hours to raise calcium levels, but improvements in bone health may take several weeks to months.
A: Do not take additional calcium or vitamin D supplements without consulting your doctor, as it may lead to high calcium levels.
A: It can be safe if monitored properly. Regular kidney function tests are advised, especially if you have kidney disease.
A: Take it as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for nidcal cl tablet
View AllAlternative brands with exact same active ingredient:
-
affocal-ct softgelAcmedix Pharma LLP ₹45.94 44.3% CHEAPER
-
zemcy soft gelatin capsuleRhophic Health Care ₹92.81 12.5% COSTLIER
-
ridabone-ct soft gelatin capsuleKelly Pharmaceuticals Pvt Ltd ₹112.50 36.4% COSTLIER
-
calscy softgel capsuleScythian Healthcare ₹117.19 42% COSTLIER
-
calceto softgel capsuleMalens Pharmaceuticals Private Limited ₹118.13 43.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a doctor's prescription.
Fact: This is a prescription medicine and should only be taken under medical supervision. - Myth: More calcium always means stronger bones.
Fact: Excess calcium can be harmful and lead to kidney stones and other complications. - Myth: This medicine can replace a healthy diet.
Fact: It supplements but does not replace a balanced diet rich in calcium and vitamin D.
🔄 Alternative Options
Generic Alternatives
- Calcitriol + Calcium Carbonate softgel capsules
Brand Alternatives
- Affocal-CT Softgel