Nidal P 100mg/500mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is nidal p 100mg/500mg tablet used for?
This medicine is a combination of nifedipine (a calcium channel blocker) and paracetamol (an analgesic). It is used to treat high blood pressure accompanied by pain. It works by relaxing blood vessels and reducing pain signals.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nidal p 100mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा निफेडिपिन और पैरासिटामोल का संयोजन है। इसका उपयोग उच्च रक्तचाप के साथ दर्द के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है और दर्द को कम करती है।
साइड इफेक्ट्स: सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर लालिमा, मतली और पेट की परेशानी शामिल हैं। गंभीर दुष्प्रभावों में गंभीर निम्न रक्तचाप, धड़कन, और यकृत विषाक्तता शामिल हो सकते हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब से बचें क्योंकि इससे यकृत को नुकसान और रक्तचाप में गिरावट हो सकती है। यदि आपको यकृत या गुर्दे की समस्या है, या आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। बिना डॉक्टर की सलाह के लंबे समय तक इसका उपयोग न करें।
💊 nidal p 100mg/500mg tablet Uses & Benefits
[{"condition":"Hypertension with pain","description":"Used to manage high blood pressure while providing pain relief.","evidence":"Well-established for nifedipine; paracetamol for pain is well-established."},{"condition":"Angina with concomitant pain","description":"Nifedipine relieves angina by dilating coronary arteries; paracetamol addresses pain.","evidence":"Well-established for nifedipine; paracetamol for pain is well-established."},{"condition":"Musculoskeletal pain in hypertensive patients","description":"Provides pain relief without causing significant blood pressure elevation.","evidence":"Common clinical practice."}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Nifedipine has been used off-label to prevent migraines, but combination with paracetamol is not standard.","evidence":"Limited"}]
Primary treatment for: Hypertension with pain
Also treats: Angina, Musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nidal p 100mg/500mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Nifedipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle cells, leading to vasodilation and reduced peripheral resistance. Paracetamol acts primarily in the central nervous system to produce analgesia and antipyresis, though its exact mechanism is not fully understood. Together, they provide blood pressure control and pain relief.
Mechanism Steps
💡 How to Take nidal p 100mg/500mg tablet
Strength: Tablet containing nifedipine 100 mg and paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally, typically once or twice daily as prescribed by your doctor. The dose may be adjusted based on your condition, blood pressure, and response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of nifedipine, especially hypotension. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose should not exceed the prescribed amount. Typically, nifedipine maximum is 120 mg per day and paracetamol maximum is 4000 mg per day, but this combination should not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nidal p 100mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Beta-blockers | Major | |
| Grapefruit juice | Major | |
| Cimetidine | Moderate | |
| Rifampicin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Beta-blockers
- Grapefruit juice
⚡ Moderate Interactions
- Cimetidine
- Rifampicin
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of nifedipine and increase the risk of liver toxicity from paracetamol. Avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to nifedipine or paracetamol","Severe liver disease","Severe kidney impairment","Cardiogenic shock","Severe aortic stenosis","Recent myocardial infarction","Pregnancy (relative)"]
⚠️ Warnings & Precautions
["Avoid abrupt withdrawal of nifedipine as it may worsen angina.","Use with caution in patients with heart failure.","Monitor blood pressure regularly.","Do not exceed recommended dose of paracetamol due to risk of liver damage.","Avoid alcohol.","Consult doctor before use in elderly or debilitated patients."]
🤱 Lactation Safety
Nifedipine and paracetamol are excreted in breast milk in small amounts. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause severe hypotension, bradycardia, and liver toxicity from paracetamol. Seek immediate medical attention. Treatment is supportive and may include activated charcoal, intravenous fluids, and N-acetylcysteine for paracetamol toxicity.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and enhance the blood pressure-lowering effect. Inform your doctor if you have liver or kidney problems, heart conditions, or if you are pregnant or breastfeeding. Do not use this medicine for prolonged periods without medical supervision. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely for dizziness and falls.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy or are pregnant. This medicine should only be used if clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with anesthetic agents and affect blood pressure.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. It may affect blood pressure and bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until you know how this medicine affects you, as it may cause dizziness or low blood pressure.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may affect your ability to perform tasks requiring alertness.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Abrupt withdrawal of nifedipine can worsen angina or increase blood pressure. Your doctor will advise when and how to stop safely.
📅 Long-Term Use Effects
Long-term use may require regular monitoring of blood pressure, liver and kidney function. Nifedipine can cause peripheral edema and may affect heart function. Paracetamol long-term use should not exceed recommended doses due to liver toxicity risk. Regular follow-up with your doctor is essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedDiet and exercise can help manage blood pressure and pain.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. Consult your doctor before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30-60 minutes for pain relief and blood pressure reduction.
A: It is best taken with food to reduce stomach upset.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: It is safe to double the dose if you miss one.
Fact: Doubling the dose can lead to serious side effects. Follow the missed dose instructions.
🔄 Alternative Options
Generic Alternatives
- Nifedipine + Paracetamol combination generics may be available.
Brand Alternatives
- Not established from the available information.