Nicorandil 16mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness, fainting, or blurred vision
- Chest pain that does not go away with rest or usual medication
- Painful mouth ulcers or skin ulcers
- Swelling of face, lips, or throat
- Difficulty breathing
- Irregular or very fast heartbeat
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is nicort 16mg tablet used for?
This medicine is a prescription oral tablet containing nicorandil 16 mg. It is used to prevent angina chest pain by widening blood vessels and improving blood flow to the heart. It is taken twice daily as prescribed by a doctor.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nicort 16mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा निकोरंडिल 16 मिलीग्राम की एक प्रिस्क्रिप्शन टैबलेट है। इसका उपयोग एंजाइना पेक्टोरिस (सीने में दर्द) को रोकने और इलाज करने के लिए किया जाता है। यह रक्त वाहिकाओं को फैलाकर हृदय तक रक्त का प्रवाह बढ़ाती है और हृदय पर दबाव कम करती है। यह दवा उन वयस्कों के लिए है जिन्हें अन्य दवाओं के बावजूद एंजाइना की समस्या बनी रहती है। इसे डॉक्टर की सलाह के अनुसार नियमित रूप से लेना चाहिए। यह तीव्र एंजाइना हमले के लिए तुरंत राहत देने वाली दवा नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चेहरे पर लालिमा, चक्कर आना, मतली और उल्टी शामिल हैं। ये आमतौर पर हल्के होते हैं और समय के साथ कम हो सकते हैं। कुछ लोगों में रक्तचाप कम हो सकता है, जिससे चक्कर आना या बेहोशी हो सकती है। मुँह के छाले, त्वचा के छाले या जननांगों पर छाले एक गंभीर दुष्प्रभाव हो सकते हैं; अगर ऐसा हो तो तुरंत डॉक्टर से मिलें। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर निम्न रक्तचाप और एलर्जी प्रतिक्रिया शामिल हैं।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से खुराक न बदलें और न ही दवा बंद करें। टैबलेट को पानी के साथ पूरा निगलें, चबाएं नहीं। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन हर दिन एक ही समय पर लें। इस दवा के साथ शराब न लें क्योंकि इससे रक्तचाप कम हो सकता है और चक्कर आ सकते हैं। सिल्डेनाफिल जैसी दवाएं इस दवा के साथ न लें क्योंकि इससे खतरनाक रूप से रक्तचाप गिर सकता है। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। मुँह या त्वचा पर छाले दिखने पर तुरंत डॉक्टर को बताएं।
💊 nicort 16mg tablet Uses & Benefits
[{"condition":"Chronic stable angina pectoris","description":"This medicine is used to reduce the frequency and severity of angina attacks in adults who remain symptomatic despite standard anti-anginal therapy.","evidence":"Well-established"},{"condition":"Unstable angina pectoris","description":"This medicine may be used as part of treatment for unstable angina under close medical supervision.","evidence":"Established"},{"condition":"Adjunctive therapy in ischemic heart disease","description":"It is sometimes added to other anti-anginal medicines to improve symptoms and exercise tolerance.","evidence":"Established"}]
Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Some studies have explored the use of nicorandil to protect kidney function during procedures using contrast dye, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Raynaud's phenomenon","description":"Rarely, nicorandil has been tried for improving blood flow in Raynaud's phenomenon, but evidence is insufficient.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Coronary artery disease, Ischemic heart disease
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nicort 16mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | HORMONES |
| Action Class | Glucocorticoids |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by opening ATP-sensitive potassium channels in the smooth muscle cells of blood vessels. This leads to an efflux of potassium ions, which causes the cell membrane to hyperpolarize and reduces calcium entry into the cell. The result is relaxation and widening of blood vessels, particularly the coronary arteries and veins. Additionally, this medicine has a nitrate-like effect that increases cyclic guanosine monophosphate (cGMP) levels, further promoting vasodilation. By dilating coronary arteries, it improves blood supply to the heart muscle. By dilating peripheral veins, it reduces preload and cardiac workload. These combined actions help relieve and prevent angina.
Mechanism Steps
💡 How to Take nicort 16mg tablet
Strength: 16 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mg to 20 mg taken twice daily. The dose may be started at 5 mg twice daily and increased gradually based on response and tolerability. The maximum recommended daily dose is 40 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be needed in patients with severe renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Dose adjustment may be needed in patients with severe hepatic impairment. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | 40 mg per day in divided doses. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nicort 16mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Nitroglycerin | Major | |
| Riociguat | Major | |
| Alcohol | Moderate | |
| Beta-blockers | Moderate | |
| ACE inhibitors | Moderate | |
| Calcium channel blockers | Moderate | |
| Diuretics | Moderate | |
| NSAIDs | Minor |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
- Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
- Riociguat
⚡ Moderate Interactions
- Alcohol
- Antihypertensive medicines (e.g., beta-blockers, ACE inhibitors, calcium channel blockers)
- Diuretics
🍷 Alcohol Interaction
Alcohol may increase the blood pressure-lowering effect of this medicine and lead to dizziness, light-headedness, or fainting. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to nicorandil or any component of the tablet","Cardiogenic shock","Severe hypotension (low blood pressure)","Left ventricular failure with low filling pressure","Concomitant use with phosphodiesterase-5 inhibitors (e.g., sildenafil)","Concomitant use with riociguat","Certain heart valve problems (e.g., aortic stenosis)"]
⚠️ Warnings & Precautions
["This medicine can cause severe hypotension, especially when used with other vasodilators or alcohol.","Mouth ulcers, skin ulcers, and genital ulcers have been reported. If any ulcer develops, stop the medicine and consult your doctor.","Use with caution in patients with low blood pressure, heart failure, or recent heart attack.","Avoid use with erectile dysfunction medicines.","Dose adjustment may be needed in elderly patients and those with liver or kidney disease.","Do not use this medicine to treat an acute angina attack; it is for prevention.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose of this medicine can cause severe hypotension, tachycardia, and fainting. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic, including intravenous fluids and vasopressors if needed. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Swallow the tablet whole with a glass of water; do not crush or chew it. You may take it with or without food, but taking it at the same time each day helps maintain steady levels. Avoid alcohol while taking this medicine because it can increase the risk of low blood pressure and dizziness. Do not take erectile dysfunction medicines such as sildenafil, tadalafil, or vardenafil while on this medicine, as this combination can cause a life-threatening drop in blood pressure. Inform your doctor if you have low blood pressure, heart valve problems, or kidney or liver disease. If you become pregnant, plan to become pregnant, or are breastfeeding, talk to your doctor before continuing this medicine. Keep all follow-up appointments and report any new symptoms, especially mouth or skin ulcers, to your doctor immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Dose adjustment may be needed based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before continuing this medicine. The safety of this medicine in pregnancy is not well established. Your doctor will weigh the benefits and risks and may switch you to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be temporarily stopped or adjusted to prevent blood pressure fluctuations during surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may cause dizziness or low blood pressure during the procedure. Your dentist may take precautions such as monitoring your blood pressure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine, but avoid sudden strenuous activities that can trigger angina. If you experience chest pain, dizziness, or shortness of breath during exercise, stop and rest. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or low blood pressure, which can affect your ability to drive or operate heavy machinery. Avoid these activities until you know how the medicine affects you. Most people can continue their normal daily activities with appropriate precautions.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects such as persistent ulcers, severe hypotension, or allergic reactions, contact your doctor immediately. Your doctor will decide whether to adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well tolerated. However, regular monitoring of blood pressure, heart rate, and symptoms is advised. Rarely, long-term use may be associated with the development of ulcers. Periodic liver and kidney function tests may be recommended. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Heart-healthy diet, regular exercise, smoking cessation, and stress management can complement medicine for angina.
Evidence: Well-establishedSupervised exercise and education programs can improve cardiovascular health and reduce angina symptoms.
Evidence: Well-establishedAngioplasty or bypass surgery may be considered for severe coronary artery disease.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. Store at room temperature and avoid direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 minutes, but its full benefits in reducing angina frequency may take a few weeks of regular use.
A: Yes, you can take it with or without food. Taking it at the same time each day is more important.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop taking this medicine without consulting your doctor. Stopping suddenly may worsen your angina.
A: The safety of this medicine in pregnancy is not well established. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken for an acute angina attack.
Fact: This medicine is for prevention of angina, not for immediate relief of an acute attack. Use fast-acting nitrates for acute attacks as prescribed. - Myth: This medicine is safe to take with erectile dysfunction medicines.
Fact: Combining this medicine with erectile dysfunction medicines can cause a dangerous drop in blood pressure and is contraindicated. - Myth: Once you feel better, you can stop this medicine.
Fact: Do not stop this medicine without consulting your doctor. Stopping suddenly may worsen angina.
🔄 Alternative Options
Generic Alternatives
- Nicorandil 16 mg tablet
Brand Alternatives
- Nicorandil 16 mg tablet (various brands)