Levazeo Od 200mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- High fever with severe muscle stiffness, confusion, or sweating (possible neuroleptic malignant syndrome).
- Palpitations, fainting, or irregular heartbeat (possible QT prolongation or arrhythmia).
- Uncontrollable movements of the face, tongue, lips, or limbs (possible tardive dyskinesia).
- Severe allergic reaction with swelling of the face, lips, throat, or difficulty breathing.
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain (possible liver problem).
- Sudden severe dizziness, fainting, or falls.
- Unusual breast tenderness, milk secretion, or menstrual changes.
- Signs of infection such as persistent fever, sore throat, or easy bruising (possible blood disorder).
If experiencing severe symptoms, call emergency services immediately.
What is nexipride 200mg tablet sr used for?
This medicine contains Levosulpiride 200 mg, a prescription medicine used to treat nausea, vomiting, and functional dyspepsia. It works by blocking dopamine receptors in the brain and gut, which reduces nausea and improves stomach emptying. It is usually taken once daily before breakfast. Common side effects include drowsiness, dizziness, and dry mouth. It should not be taken by people with pheochromocytoma, uncontrolled epilepsy, or severe kidney or liver disease.
- Generic Name: Levosulpiride (200mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nexipride 200mg tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोसल्पिराइड 200 मिलीग्राम युक्त एक प्रिस्क्रिप्शन टैबलेट है। इसका उपयोग मुख्य रूप से मतली, उल्टी, पेट फूलना, अपच और गैस्ट्रोपेरेसिस (पेट खाली होने में देरी) के इलाज के लिए किया जाता है। यह दवा दिमाग और पेट में डोपामिन रिसेप्टर्स को ब्लॉक करके काम करती है, जिससे मतली कम होती है और पेट की गति बढ़ती है। यह दवा आमतौर पर दिन में एक बार सुबह नाश्ते से पहले ली जाती है। इस दवा को डॉक्टर की सलाह के बिना नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, कब्ज, और थकान शामिल हैं। कुछ लोगों में स्तनों में दर्द, दूध का स्राव, या मासिक धर्म में अनियमितता हो सकती है क्योंकि यह दवा प्रोलैक्टिन हार्मोन को बढ़ा सकती है। गंभीर दुष्प्रभावों में दिल की धड़कन में गड़बड़ी, मांसपेशियों में अकड़न, बुखार, और शरीर के अनैच्छिक हिलने-डुलने की समस्या शामिल हैं। अगर आपको ऐसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बढ़ाएँ और न घटाएँ। इसे रोज एक ही समय पर लें। गोली को पानी के साथ पूरा निगलें, चबाएँ नहीं। इस दवा के साथ शराब न पिएँ क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएँ। डॉक्टर की सलाह के बिना दवा अचानक बंद न करें।
💊 nexipride 200mg tablet sr Uses & Benefits
[{"condition":"Nausea and vomiting","description":"This medicine blocks dopamine receptors in the brain's vomiting centre, which helps control nausea and vomiting from various causes.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"It improves stomach emptying and reduces symptoms of fullness, bloating, and upper abdominal discomfort.","evidence":"Well-established"},{"condition":"Diabetic gastroparesis","description":"This medicine helps speed up delayed gastric emptying in people with diabetes, reducing nausea and early satiety.","evidence":"Moderate"},{"condition":"Somatoform disorders","description":"Low doses are sometimes used to treat persistent physical complaints that have no clear medical cause, often alongside psychological support.","evidence":"Limited"},{"condition":"Depression with somatic symptoms","description":"In some countries, low-dose Levosulpiride is used as an add-on treatment for depression that comes with physical symptoms.","evidence":"Limited"}]
Off-label uses: [{"condition":"Premature ejaculation","description":"Some small studies suggest Levosulpiride may help delay ejaculation, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Tourette syndrome","description":"Because it blocks dopamine, it has been tried for tic disorders, but evidence is not strong enough for routine use.","evidence":"Limited"}]
Primary treatment for: Functional dyspepsia
Also treats: Diabetic gastroparesis, Nausea and vomiting, Somatoform disorders, Depression with somatic symptoms
📋 Drug Information
| Generic Name(s) | Levosulpiride (200mg) |
| Brand Name | nexipride 200mg tablet sr |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Atypical Antipsychotics |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15°C and 30°C, in a dry place. Keep it away from direct sunlight and moisture. Do not store it in the bathroom. Keep the tablets in their original container, tightly closed, and out of the reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture, but you should always check the expiry date printed on the pack. Do not use the medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works mainly by blocking dopamine D2 receptors in the brain and in the gastrointestinal tract. In the brain, this action suppresses the chemoreceptor trigger zone and the vomiting centre, which reduces nausea and vomiting. In the stomach and upper intestine, blocking dopamine receptors enhances the release of acetylcholine, which strengthens gastric contractions and speeds up the movement of food through the digestive tract. Levosulpiride also has weak serotonin 5-HT4 receptor agonist activity, which adds to its prokinetic effect. At higher doses, it can affect mood by modulating dopamine pathways in the limbic system, which is why it sometimes helps with depression and somatoform disorders.
Mechanism Steps
💡 How to Take nexipride 200mg tablet sr
Strength: This medicine is available as an immediate-release oral tablet containing Levosulpiride 200 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one 200 mg tablet taken once daily, preferably in the morning before breakfast, or as directed by your doctor. However, the dose and frequency depend on the condition being treated, your age, kidney and liver function, and other medicines you are taking. For nausea and vomiting, a lower dose may be used. For functional dyspepsia or gastroparesis, the dose may be adjusted based on response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients, especially those above 65 years, may be more sensitive to the side effects of this medicine, particularly drowsiness, dizziness, and movement disorders. A lower starting dose may be considered, and kidney function should be checked before and during treatment. Dose must be individualized by a qualified clinician based on renal function and overall health. |
| Renal Impairment | In patients with mild to moderate kidney impairment, no dose adjustment may be needed, but caution is advised. In severe kidney impairment, the dose may need to be reduced or the medicine avoided, as Levosulpiride is excreted mainly by the kidneys. Dose must be individualized by a qualified clinician based on creatinine clearance and clinical response. |
| Hepatic Impairment | In patients with mild to moderate liver impairment, no specific dose adjustment is established, but caution is advised. In severe liver impairment, this medicine should be used with caution or avoided because its metabolism may be affected. Dose must be individualized by a qualified clinician based on liver function tests and clinical assessment. |
| Maximum Daily Dose | The maximum recommended daily dose of Levosulpiride is 200 mg, but this may vary depending on the indication and the patient's condition. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nexipride 200mg tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Metoclopramide | Major | |
| Amiodarone | Major | |
| Levodopa | Major | |
| Alcohol | Major | |
| Antihypertensives | Moderate | |
| Benzodiazepines | Moderate | |
| Trihexyphenidyl | Moderate | |
| Antacids | Minor | |
| Opioids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Other dopamine antagonists (e.g., metoclopramide, haloperidol)
- QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol, citalopram)
- Levodopa and other dopamine agonists
- Alcohol
⚡ Moderate Interactions
- Antihypertensive drugs
- Sedatives and hypnotics (e.g., benzodiazepines, zolpidem)
- Anticholinergic drugs (e.g., trihexyphenidyl, benztropine)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Both alcohol and Levosulpiride can depress the central nervous system, leading to increased drowsiness, dizziness, and impaired judgment. Combining them can also increase the risk of falls and accidents. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to Levosulpiride or any other ingredient in this medicine","Pheochromocytoma (a tumour of the adrenal gland)","Uncontrolled epilepsy or a history of seizures","Severe kidney impairment (unless under specialist supervision)","Severe liver impairment","Concurrent use with levodopa or other dopamine agonists in Parkinson's disease","Breast cancer (because Levosulpiride increases prolactin, which can stimulate certain breast cancers)","Prolactin-dependent tumours","Children below 18 years of age (safety and effectiveness not established)"]
⚠️ Warnings & Precautions
["This medicine can cause drowsiness and dizziness. Do not drive or operate heavy machinery until you know how it affects you.","Avoid alcohol while taking this medicine because it increases sedation and other central nervous system effects.","Tell your doctor if you have a history of heart rhythm problems, low potassium or magnesium levels, or if you take other medicines that affect heart rhythm.","This medicine can increase prolactin levels, which may cause breast tenderness, milk secretion, and menstrual irregularities. Report these symptoms to your doctor.","Long-term use may cause involuntary movements (tardive dyskinesia). Report any unusual facial or tongue movements immediately.","Do not stop this medicine suddenly without consulting your doctor, as withdrawal symptoms such as nausea, vomiting, and restlessness can occur.","Use with caution in elderly patients, who are more sensitive to the sedative and movement-related side effects.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","This medicine may affect blood sugar control in people with diabetes. Monitor your blood sugar more frequently.","Keep all follow-up appointments so your doctor can monitor for side effects and adjust the dose if needed."]
🤱 Lactation Safety
Levosulpiride may pass into breast milk and could affect the nursing infant. Because it can increase prolactin levels and cause other effects, breastfeeding is not recommended while taking this medicine unless your doctor advises otherwise. Discuss alternative feeding options with your doctor.
💊 Overdose Management
If you suspect an overdose of this medicine, seek emergency medical help immediately. Symptoms of overdose may include severe drowsiness, confusion, uncontrollable muscle movements, abnormal heart rhythms, and low blood pressure. There is no specific antidote for Levosulpiride overdose. Treatment is supportive and may include activated charcoal if the overdose was recent, intravenous fluids, and monitoring of heart rhythm and vital signs. Do not try to induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided it is not almost time for your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Always take this medicine exactly as your doctor has prescribed. Do not increase or decrease the dose on your own. Take the tablet at the same time each day to maintain steady levels in your body. Swallow the tablet whole with a glass of water; do not crush or chew it unless your doctor or pharmacist has told you it is safe to do so. Avoid drinking alcohol while taking this medicine because alcohol can increase drowsiness and dizziness. Tell your doctor about all other medicines you are taking, especially medicines for heart rhythm problems, antidepressants, antipsychotics, and Parkinson's disease medicines, as serious interactions can occur. If you have kidney or liver problems, your doctor may need to adjust the dose or monitor you more closely. Do not stop this medicine suddenly without talking to your doctor, because stopping abruptly can cause withdrawal symptoms such as nausea, vomiting, and restlessness. Keep all follow-up appointments so your doctor can check your heart rhythm, prolactin levels, and movement symptoms if you need long-term treatment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients, especially those above 65 years, are more sensitive to the side effects of this medicine, particularly drowsiness, dizziness, and movement disorders. They may also have reduced kidney function, which can cause the medicine to accumulate in the body. A lower starting dose may be considered, and kidney function should be checked before and during treatment. Regular monitoring for falls and movement symptoms is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before taking this medicine. The safety of Levosulpiride during pregnancy is not well established. Your doctor may consider alternative treatments or adjust your therapy. If you become pregnant while taking this medicine, contact your doctor immediately.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your surgeon and anaesthesiologist that you are taking this medicine. It can interact with anaesthetic agents and other medicines used during surgery, and it may affect heart rhythm. Your doctor may advise you to stop the medicine temporarily before surgery. Do not stop it on your own without medical advice.
🦷 Dental Procedures
Before any dental procedure, inform your dentist that you are taking this medicine. It can cause dry mouth, which may increase the risk of dental problems. It may also interact with medicines used during dental procedures, such as sedatives. Your dentist may recommend taking extra care with oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, especially when you first start taking it. Avoid strenuous exercise or activities that require balance and coordination until you know how the medicine affects you. If you feel dizzy or lightheaded during exercise, stop immediately and rest. Light to moderate exercise, such as walking, is generally safe and can help with digestion.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks that require alertness. It is best to avoid driving or operating heavy machinery until you know how the medicine affects you. If your job requires high concentration, discuss with your doctor about timing the dose to minimize impact. Most people can continue their normal daily activities with caution.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as abnormal heart rhythms, severe movement disorders, or signs of an allergic reaction, seek immediate medical attention and your doctor will advise whether to stop the medicine. If you have been taking it for a long time, your doctor may recommend a gradual dose reduction to avoid withdrawal symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of tardive dyskinesia, a condition characterized by involuntary movements of the face, tongue, and limbs, which can sometimes be permanent. It can also cause persistent elevation of prolactin levels, leading to breast tenderness, milk secretion, and menstrual irregularities. Regular monitoring of movement symptoms, prolactin levels, and heart rhythm is recommended for patients on long-term therapy. The need for continued treatment should be reviewed periodically by your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent, low-fat meals can help manage functional dyspepsia and gastroparesis symptoms.
Evidence: Well-establishedTechniques such as yoga, meditation, and cognitive behavioural therapy can help reduce stress-related stomach symptoms.
Evidence: ModerateMedicines like domperidone or metoclopramide may be alternatives, but they have their own side effects and should be discussed with your doctor.
Evidence: Well-establishedSome studies suggest acupuncture may help with nausea and functional dyspepsia, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a vaccine, inform your healthcare provider that you are taking this medicine. There is no need to stop the medicine before vaccination unless your doctor advises otherwise.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified on the label.
✅ DO
Keep the tablets in their original container, tightly closed.
❌ DON'T
Do not transfer them to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of the reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a letter from your doctor stating the medical reason for the medicine, especially if you are travelling internationally. Keep the medicine in your hand luggage rather than checked baggage to avoid loss or temperature extremes. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, continue taking your dose at the same time each day according to your home schedule, or ask your doctor how to adjust. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some effects on nausea and stomach emptying may begin within a few hours, but it may take a few days to weeks to notice full improvement in symptoms such as bloating and early satiety. Follow your doctor's advice and do not stop the medicine early.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset. However, it is usually recommended to take it before breakfast for best effect on stomach motility.
A: If you remember within 12 hours of the missed dose, take it as soon as you remember. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, you should avoid alcohol completely while taking this medicine. Alcohol increases drowsiness, dizziness, and the risk of accidents.
A: The safety of this medicine during pregnancy is not well established. It should be used only if your doctor decides the benefits outweigh the risks. If you are pregnant or planning to become pregnant, inform your doctor immediately.
A: Do not stop this medicine suddenly without consulting your doctor. Stopping abruptly can cause withdrawal symptoms such as nausea, vomiting, and restlessness. Your doctor will advise you on how to taper the dose if needed.
🤔 Common Patient Concerns
🔄 Substitutes for nexipride 200mg tablet sr
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a sleeping pill.
Fact: This medicine is not a sleeping pill. It is used for nausea, vomiting, and stomach motility problems. Drowsiness is a side effect, not the main purpose. - Myth: You can stop this medicine whenever you feel better.
Fact: You should not stop this medicine suddenly without consulting your doctor, as withdrawal symptoms can occur. Always follow your doctor's advice. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be avoided while taking this medicine because it increases drowsiness, dizziness, and the risk of accidents. - Myth: This medicine can be taken for any stomach problem.
Fact: This medicine is specifically for nausea, vomiting, and motility disorders. It is not a general stomach pain reliever and should only be used as prescribed.
🔄 Alternative Options
Generic Alternatives
- Levosulpiride 200 mg tablet
Brand Alternatives
- Levazeo OD 200 mg tablet