neurovoiz nt 75mg/10mg tablet - Pregabalin (75mg) + Nortriptyline (10mg) medicine

Pregabid NT Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Voizmed Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
🤰 Pregnancy Category Pregabalin: Not recommended unless clearly needed; Nortriptyline: Use with caution. Consult your doctor to weigh benefits and risks. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate to well-established for neuropathic pain.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Thoughts of harming yourself or others
  • Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Irregular or rapid heartbeat
  • Severe skin rash with blisters or peeling
  • Yellowing of eyes or skin, dark urine
  • Severe abdominal pain or persistent vomiting
  • Sudden weight gain or swelling in legs

If experiencing severe symptoms, call emergency services immediately.

What is neurovoiz nt 75mg/10mg tablet used for?

This medicine is a combination of Pregabalin and Nortriptyline used to treat neuropathic pain. It works by reducing pain signals in the nervous system and enhancing mood. It is taken orally, usually once or twice daily, and should not be stopped suddenly.

  • Generic Name: Pregabalin (75mg) + Nortriptyline (10mg)
  • Manufacturer: Voizmed Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 neurovoiz nt 75mg/10mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा न्यूरोपैथिक दर्द (नसों से जुड़ा दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह मधुमेह से होने वाले नसों के दर्द, दाद के बाद होने वाले दर्द, और फाइब्रोमायल्जिया जैसी स्थितियों में राहत देती है। यह दवा दर्द के संकेतों को कम करके और मूड को बेहतर बनाकर काम करती है।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, नींद आना, मुँह सूखना, धुंधली दृष्टि, वजन बढ़ना और हाथ-पैरों में सूजन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें आत्महत्या के विचार, गंभीर एलर्जी, अनियमित दिल की धड़कन और त्वचा पर गंभीर प्रतिक्रियाएँ हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे घबराहट, अनिद्रा और मतली जैसे लक्षण हो सकते हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएँ और मशीनरी न चलाएँ। इस दवा के साथ शराब न पिएँ। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएँ जो आप ले रहे हैं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 neurovoiz nt 75mg/10mg tablet Uses & Benefits

[{"condition":"Diabetic peripheral neuropathy","description":"This medicine helps relieve burning, shooting, and tingling pain in the feet and hands caused by nerve damage from diabetes.","evidence":"Well-established"},{"condition":"Postherpetic neuralgia","description":"It reduces persistent nerve pain that can occur after a shingles infection.","evidence":"Well-established"},{"condition":"Neuropathic pain","description":"This medicine is used for various types of nerve pain, including that from spinal cord injuries or multiple sclerosis.","evidence":"Moderate"},{"condition":"Fibromyalgia","description":"It may help reduce widespread muscle pain and improve sleep in some patients with fibromyalgia.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, especially when other treatments fail.","evidence":"Limited"},{"condition":"Generalized anxiety disorder","description":"Pregabalin component may be used off-label for anxiety, but the combination is not standard.","evidence":"Limited"}]

Primary treatment for: Neuropathic pain

Also treats: Diabetic peripheral neuropathy, Postherpetic neuralgia, Fibromyalgia

📋 Drug Information

Generic Name(s)Pregabalin (75mg) + Nortriptyline (10mg)
Brand Nameneurovoiz nt 75mg/10mg tablet
ManufacturerVoizmed Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at bedtime if it makes you drowsy during the day.
2
Do not stop this medicine abruptly; always consult your doctor for a gradual taper.
3
Monitor your mood and report any worsening depression or suicidal thoughts immediately.
4
Stay hydrated and chew sugar-free gum to manage dry mouth.
5
Rise slowly from sitting or lying positions to prevent dizziness.
6
Inform your doctor if you have kidney problems, as dose adjustment may be needed.
7
Avoid driving or operating heavy machinery until you know how this medicine affects you.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning or shooting nerve pain
This medicine is commonly prescribed for this.
Likely Use
✅
Tingling or numbness in hands and feet
This medicine is used for diabetic neuropathy.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Headache
This medicine is not for ordinary headaches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPregabalin is rapidly absorbed after oral administration, with peak plasma concentrations occurring within 1.5 hours. Nortriptyline is also well absorbed, with peak levels at 4-8 hours. Food does not significantly affect the absorption of either component.
DistributionPregabalin has a volume of distribution of approximately 0.5 L/kg and does not bind to plasma proteins. Nortriptyline is widely distributed in the body and is highly protein-bound (approximately 90-95%).
Protein BindingPregabalin does not bind to plasma proteins. Nortriptyline is approximately 90-95% bound to plasma proteins, primarily albumin.
MetabolismPregabalin undergoes negligible metabolism in humans. Nortriptyline is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2D6, to active and inactive metabolites.
Half-LifeThe elimination half-life of Pregabalin is approximately 6 hours. The elimination half-life of Nortriptyline ranges from 18 to 44 hours.
ExcretionPregabalin is excreted unchanged in the urine, with about 90% of the dose recovered in urine. Nortriptyline and its metabolites are excreted primarily in urine and to a lesser extent in feces.
BioavailabilityThe oral bioavailability of Pregabalin is approximately 90% and is independent of dose. Nortriptyline has an oral bioavailability of about 50-60% due to first-pass metabolism.
Onset of ActionPain relief from this medicine may begin within a few days, but full therapeutic effects can take 2-4 weeks.
Peak Plasma TimePregabalin reaches peak plasma levels in about 1.5 hours; Nortriptyline in about 4-8 hours.
Duration of ActionThe analgesic effect of this medicine lasts for about 12-24 hours, depending on individual factors.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P. This leads to decreased neuronal excitability and pain transmission. Nortriptyline, a tricyclic antidepressant, inhibits the reuptake of serotonin and norepinephrine in the brain, enhancing descending inhibitory pain pathways and modulating pain perception. Together, they provide synergistic relief for neuropathic pain.

Mechanism Steps

1
Pregabalin binding: Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the brain and spinal cord.
2
Reduced neurotransmitter release: This binding reduces the influx of calcium into nerve terminals, decreasing the release of pain-signaling neurotransmitters like glutamate and substance P.
3
Nortriptyline reuptake inhibition: Nortriptyline blocks the reuptake of serotonin and norepinephrine, increasing their availability in the synaptic cleft.
4
Enhanced descending inhibition: Increased neurotransmitter levels enhance the descending inhibitory pathways from the brainstem to the spinal cord, reducing pain perception.
5
Synergistic analgesia: The combined actions of Pregabalin and Nortriptyline result in more effective relief of neuropathic pain than either alone.

💡 How to Take neurovoiz nt 75mg/10mg tablet

Strength: Tablet containing Pregabalin 75 mg and Nortriptyline 10 mg.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take it with or without food, but consistently.
4If it causes drowsiness, take it at bedtime.
5Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily, or as directed by your doctor. The dose may be adjusted based on your response and tolerability. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Start with a lower dose and titrate slowly. Monitor renal function and for signs of confusion or falls.
Renal ImpairmentDose adjustment is required in patients with renal impairment. Pregabalin dose should be reduced based on creatinine clearance. Consult your doctor for specific dosing.
Hepatic ImpairmentNortriptyline dose may need reduction in patients with hepatic impairment. Monitor liver function. Consult your doctor for specific dosing.
Maximum Daily DoseThe maximum recommended daily dose is 2 tablets (Pregabalin 150 mg + Nortriptyline 20 mg) per day, but this may vary based on individual clinical judgment.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases sedation and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of neurovoiz nt 75mg/10mg tablet

✅ Common Side Effects

Dizziness (Common (10-20%))
Rise slowly from sitting or lying positions. Avoid driving until you know how it affects you.
Drowsiness (Common (10-20%))
Take the dose at bedtime if it makes you sleepy. Avoid alcohol.
Dry mouth (Common (5-15%))
Sip water frequently, chew sugar-free gum, or use a saliva substitute.
Blurred vision (Common (5-10%))
Usually temporary. Avoid driving if vision is affected. Consult doctor if persistent.
Weight gain (Common (5-10%))
Monitor weight and follow a balanced diet. Consult a dietitian if needed.
Peripheral edema (Common (5-10%))
Elevate legs when sitting. Reduce salt intake. Consult doctor if swelling worsens.

🚨 Serious Side Effects

Suicidal thoughts or behavior (Rare (<0.1%))
Seek immediate medical help if you experience thoughts of self-harm.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you have difficulty breathing, swelling of face or throat, or severe rash.
Irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you feel palpitations or faint.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek emergency care if you develop a painful rash with blisters or peeling skin.

⚠️ Rare Side Effects

Angioedema
Seek emergency care if you have swelling of the face, lips, or tongue.
Rhabdomyolysis
Report muscle pain, weakness, or dark urine immediately.
Hepatotoxicity
Report yellowing of eyes or skin, dark urine, or abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Opioids Major
Tramadol Major
SSRIs Moderate
Anticholinergics Moderate
Beta-blockers Moderate
Antacids Minor
Cimetidine Minor

🚨 Major Interactions

  • MAO inhibitors
  • CNS depressants (e.g., opioids, benzodiazepines)
  • Tramadol

⚡ Moderate Interactions

  • SSRIs (e.g., fluoxetine)
  • Anticholinergics (e.g., oxybutynin)
  • Beta-blockers

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and the risk of central nervous system depression. It may also worsen the side effects of Nortriptyline.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Pregabalin, Nortriptyline, or any component of the formulation","Recent myocardial infarction","Uncontrolled narrow-angle glaucoma","Concurrent use with MAO inhibitors","Severe liver disease"]

⚠️ Warnings & Precautions

["May cause dizziness and drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not stop abruptly; taper gradually under medical supervision to avoid withdrawal symptoms.","May increase suicidal thoughts; monitor mood closely, especially in young adults.","Use with caution in elderly patients due to increased risk of falls and confusion.","May cause peripheral edema; monitor for swelling.","Avoid alcohol and other CNS depressants.","Inform your doctor if you have kidney or liver disease, heart problems, or glaucoma."]

🤱 Lactation Safety

Pregabalin and Nortriptyline are excreted in breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor.

💊 Overdose Management

Overdose may cause severe drowsiness, confusion, tachycardia, hypotension, and respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and cardiac rhythm.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as this can cause withdrawal symptoms such as anxiety, insomnia, and nausea. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not consume alcohol while taking this medicine, as it can increase drowsiness and dizziness. Inform your doctor about all other medications you are taking, especially pain relievers, antidepressants, and blood thinners. Keep this medicine out of reach of children and store it in a cool, dry place.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of dizziness, confusion, and falls. Start with a lower dose and monitor closely. Renal function should be checked regularly.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor. This medicine may not be suitable during pregnancy. Effective contraception should be used while taking this medicine unless otherwise advised.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect pain management. Do not stop without medical advice.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth, increasing the risk of dental problems. Maintain good oral hygiene and stay hydrated.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce nerve pressure.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Practice relaxation techniques to manage stress.
💧
Get adequate sleep to help with pain modulation.
🧘
Avoid alcohol and smoking.
🌞
Follow a balanced diet rich in fruits and vegetables.

🏋️ Exercise Considerations

Avoid high-impact exercises that may worsen nerve pain. Consult your doctor before starting any new exercise regimen. If you experience dizziness, stop and rest.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed and sugary foods.
Stay well hydrated.
Eat plenty of fiber to prevent constipation.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness and dizziness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. Inform your employer if your job involves such tasks.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects, contact your doctor immediately. A gradual dose reduction is usually recommended to prevent withdrawal symptoms.

📅 Long-Term Use Effects

Long-term use may lead to weight gain, peripheral edema, and dependence. Regular monitoring of renal function, mood, and weight is advised. Do not stop abruptly; taper gradually under medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Cognitive behavioral therapy

Helps manage chronic pain and improve coping skills.

Evidence: Moderate
Acupuncture

May provide pain relief for some patients.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before receiving any live vaccines while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. If traveling across time zones, adjust dosing times gradually under medical advice. Store in a cool, dry place away from direct sunlight. Check customs regulations for controlled substances before traveling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with diabetic neuropathy
He had been suffering from burning pain in his feet for years. His doctor prescribed this medicine. After 3 weeks, he noticed significant relief in pain and improved sleep. He experienced mild drowsiness initially, which subsided after a few days. He was advised not to stop the medicine suddenly.
💡 Lesson: Consistent use and gradual titration improve outcomes. Do not stop abruptly.
👤 A 40-year-old woman with postherpetic neuralgia
After a bout of shingles, she had persistent shooting pain in her chest. This medicine was prescribed. She felt better within 2 weeks but experienced dry mouth and constipation. Her doctor advised her to increase water intake and fiber. She was able to reduce the dose after 6 months under supervision.
💡 Lesson: Side effects can be managed with lifestyle changes. Regular follow-up is important for dose adjustments.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling some relief within a few days, but full effects can take 2-4 weeks.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop suddenly. Consult your doctor for a gradual taper to avoid withdrawal symptoms.

Q: Is it safe to take with other pain medicines?

A: Inform your doctor about all medicines you take. Some combinations may increase side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for neurovoiz nt 75mg/10mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a sleeping pill.
    Fact: It is primarily for nerve pain, though it may cause drowsiness as a side effect.
  • Myth: It is addictive.
    Fact: It is not addictive in the traditional sense, but it can cause dependence and withdrawal if stopped abruptly.
  • Myth: It can be taken for any type of pain.
    Fact: It is specifically for neuropathic pain, not for ordinary headaches or muscle strains.

🔄 Alternative Options

Generic Alternatives

  • Pregabalin 75 mg + Nortriptyline 10 mg tablet (various manufacturers)

Brand Alternatives

  • Pregabid NT Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Pregabalin + Nortriptyline","composition":"Pregabalin 75 mg + Nortriptyline 10 mg","uses":"Neuropathic pain","notes":"Combination for better pain relief."},{"medicine":"Pregabalin alone","composition":"Pregabalin 75 mg","uses":"Neuropathic pain, epilepsy, anxiety","notes":"No antidepressant component."},{"medicine":"Nortriptyline alone","composition":"Nortriptyline 10 mg","uses":"Depression, neuropathic pain","notes":"No anticonvulsant component."}]

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