netalo eye drop - Netarsudil (0.02% w/v) medicine

Netalo Eye Drop (netarsudil 0.02%): Complete Medicine Guide

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🏭 Ajanta Pharma Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 31, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for lowering intraocular pressure in open-angle glaucoma and ocular hypertension.
Reviewed by
SaathiMed Expert Panel | Oct 31, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden loss of vision or severe decrease in vision
  • Severe eye pain or severe redness that worsens
  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Signs of eye infection such as discharge, crusting, or increased sensitivity to light
  • Severe headache with nausea or vomiting
  • Eye injury or trauma while using this medicine

If experiencing severe symptoms, call emergency services immediately.

What is netalo eye drop used for?

This medicine is a prescription eye drop containing netarsudil 0.02% w/v. It is used once daily in the evening to lower high eye pressure in adults with open-angle glaucoma or ocular hypertension. It works by improving fluid drainage from the eye.

  • Generic Name: Netarsudil (0.02% w/v)
  • Manufacturer: Ajanta Pharma Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 netalo eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा नेटारसुडिल 0.02% व/व युक्त आई ड्रॉप है, जिसका उपयोग खुले कोण वाले ग्लूकोमा और ऑक्यूलर हाइपरटेंशन में आंखों के अंदर के दबाव को कम करने के लिए किया जाता है। यह आंखों में तरल पदार्थ के निकास को बेहतर बनाकर काम करती है, जिससे आंखों का दबाव कम होता है और ऑप्टिक नर्व को नुकसान से बचाया जा सकता है। इस दवा का उपयोग आमतौर पर रात में एक बार प्रभावित आंख में एक बूंद डालकर किया जाता है। यह दवा ग्लूकोमा का इलाज नहीं है, लेकिन नियमित उपयोग से दृष्टि की रक्षा में मदद मिलती है।

साइड इफेक्ट्स: इस दवा के सबसे आम दुष्प्रभावों में आंखों का लाल होना, आंखों में दर्द, धुंधली दृष्टि, आंखों में जलन और पानी आना शामिल हैं। कुछ मरीजों में कॉर्निया पर छोटे बिंदु जैसे जमाव दिखाई दे सकते हैं, लेकिन ये आमतौर पर दृष्टि को प्रभावित नहीं करते और दवा बंद करने पर ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आंखों में तेज दर्द, अचानक दृष्टि में कमी, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले और बाद में अपने हाथ अच्छी तरह धोएं। आंख में बूंद डालते समय ड्रॉपर की नोक को आंख या किसी सतह से न छुएं। बूंद डालने के बाद आंख को धीरे से 1-2 मिनट बंद रखें और नाक के पास वाले कोने पर हल्का दबाव डालें। यदि आप कॉन्टैक्ट लेंस पहनते हैं, तो बूंद डालने से पहले उन्हें निकाल लें और कम से कम 15 मिनट बाद ही वापस लगाएं। इस दवा को बच्चों की पहुंच से दूर रखें और समाप्ति तिथि के बाद उपयोग न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 netalo eye drop Uses & Benefits

[{"condition":"Open-angle glaucoma","description":"This medicine lowers elevated intraocular pressure in adults with open-angle glaucoma by improving aqueous humor outflow through the trabecular meshwork.","evidence":"Well-established"},{"condition":"Ocular hypertension","description":"This medicine is used to reduce high eye pressure in patients with ocular hypertension who are at risk of developing glaucoma.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Normal-tension glaucoma","description":"Sometimes considered by eye specialists for patients with glaucoma-like optic nerve damage despite normal eye pressure, but this is not a standard approved use.","evidence":"Limited"}]

Primary treatment for: Open-angle glaucoma and ocular hypertension

Also treats: Normal-tension glaucoma (off-label), Pseudoexfoliation glaucoma (limited evidence)

📋 Drug Information

Generic Name(s)Netarsudil (0.02% w/v)
Brand Namenetalo eye drop
ManufacturerAjanta Pharma Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassRho kinase inhibitor
Route of AdministrationOphthalmic (topical eye instillation)
StorageStore this medicine at room temperature between 15°C and 30°C (59°F to 86°F). Protect it from light and excessive heat. Do not freeze. Keep the bottle tightly closed when not in use.
Shelf LifeThe shelf life of this medicine is typically 24 months from the date of manufacture, but refer to the expiry date printed on the bottle. Once opened, discard after 4 weeks unless otherwise instructed by your eye doctor.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Use this medicine exactly once daily in the evening unless your eye doctor advises otherwise.
2
Wait at least 5 minutes between this medicine and any other eye drops you use.
3
Remove contact lenses before instilling this medicine and wait 15 minutes before reinserting them.
4
Do not touch the dropper tip to your eye or any surface to prevent contamination.
5
Attend all scheduled eye check-ups to monitor your eye pressure and corneal health.
6
Report any persistent eye redness, pain, or vision changes to your eye doctor promptly.
7
Do not stop using this medicine suddenly without consulting your eye doctor, even if your eyes feel fine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High eye pressure
This medicine is commonly prescribed for this condition.
Likely Use
✅
Open-angle glaucoma
This medicine is approved for this condition.
Likely Use
❌
Eye infection
This medicine is not an antibiotic and should not be used for eye infections.
Not Primary
❌
Dry eye
This medicine is not a lubricant and may worsen dryness in some patients.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed through the cornea and other tissues of the eye after topical instillation. Systemic absorption is minimal but can occur through the nasolacrimal duct. Not established from the available information for specific absorption percentages.
DistributionAfter absorption into the eye, this medicine distributes into the aqueous humor and surrounding ocular tissues. Plasma protein binding is not established from the available information.
Protein BindingNot established from the available information.
MetabolismThis medicine is metabolized in the eye and systemically, primarily by esterases and possibly by hepatic enzymes. The exact metabolic pathways are not fully established from the available information.
Half-LifeThe elimination half-life of this medicine from the eye is not established from the available information. The plasma half-life is also not well established.
ExcretionThis medicine and its metabolites are excreted primarily in the urine and feces. The exact proportions are not established from the available information.
BioavailabilitySystemic bioavailability after topical eye administration is very low. Ocular bioavailability is not established from the available information.
Onset of ActionThe pressure-lowering effect of this medicine begins within 2 to 4 hours after instillation.
Peak Plasma TimePeak plasma concentrations are very low and occur within 1 to 2 hours after instillation. Not established from the available information for exact values.
Duration of ActionThe intraocular pressure-lowering effect of this medicine lasts for approximately 24 hours, which supports once-daily dosing.

How It Works

This medicine works by inhibiting Rho kinase enzymes in the trabecular meshwork and Schlemm canal of the eye. This inhibition relaxes the cells and fibers in the drainage pathway, allowing aqueous humor to flow out of the eye more easily. It also reduces the production of aqueous humor to some extent and may slightly dilate the episcleral veins, which further helps lower intraocular pressure. The overall effect is a reduction in the pressure inside the eye, which protects the optic nerve from damage.

Mechanism Steps

1
Inhibition of Rho kinase: This medicine enters the eye and inhibits Rho kinase enzymes in the trabecular meshwork and Schlemm canal.
2
Relaxation of drainage pathway: Inhibition of Rho kinase causes the cells and fibers in the drainage pathway to relax, widening the channels for fluid outflow.
3
Increased aqueous humor outflow: With the drainage pathway relaxed, aqueous humor flows out of the eye more efficiently, reducing intraocular pressure.
4
Reduced aqueous humor production: This medicine also partially reduces the production of aqueous humor, adding to the pressure-lowering effect.
5
Protection of optic nerve: Lower intraocular pressure reduces mechanical stress on the optic nerve head, helping to prevent further vision loss in glaucoma.

💡 How to Take netalo eye drop

Strength: Ophthalmic solution containing netarsudil 0.02% w/v (0.2 mg/mL).

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently if instructed on the label.
3Tilt your head back and look up at the ceiling.
4Pull down your lower eyelid to create a small pocket.
5Squeeze one drop into the pocket without touching the dropper to your eye.
6Close your eye gently for 1 to 2 minutes and press the inner corner near your nose.
7Wipe away any excess liquid with a clean tissue.
8Replace the cap tightly and wash your hands again.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one drop in the affected eye once daily in the evening. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Do not change the dose or frequency without consulting your eye doctor. If you use other eye drops, wait at least 5 minutes between each medicine.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatric ophthalmologist.
Elderly DosageNo specific dose adjustment is required for elderly patients based on age alone. However, elderly patients should be monitored for eye redness, corneal changes, and other side effects. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo dose adjustment is established for patients with renal impairment. Since systemic absorption is minimal, significant renal effects are unlikely. Consult your doctor for guidance.
Hepatic ImpairmentNo dose adjustment is established for patients with hepatic impairment. Since systemic absorption is minimal, significant hepatic effects are unlikely. Consult your doctor for guidance.
Maximum Daily DoseThe maximum recommended daily dose is one drop in the affected eye once daily. Do not exceed this unless directed by your eye doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No specific food restrictions
No timing restrictions with food
This medicine is applied topically to the eye and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with your regular evening schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up. Resume your normal schedule the next evening.

⚠️ Side Effects of netalo eye drop

✅ Common Side Effects

Conjunctival hyperemia (eye redness) (Very common (up to 50%))
This usually lessens over time. If it becomes severe or painful, contact your eye doctor.
Cornea verticillata (whorl-like corneal deposits) (Common (about 20%))
These deposits usually do not affect vision and resolve when the medicine is stopped. Your eye doctor will monitor them.
Eye pain or discomfort (Common (5-10%))
This often occurs right after instillation and fades quickly. If it persists, consult your eye doctor.
Blurred vision (Common (5-10%))
Wait until vision clears before driving or using machinery. If blurred vision continues, seek medical advice.
Increased tear production (Common (5-10%))
This is usually temporary. If it becomes bothersome, talk to your eye doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, throat, or difficulty breathing.
Severe eye inflammation (Rare (<0.1%))
Contact your eye doctor right away if you have severe eye pain, redness, or sensitivity to light.
Corneal damage affecting vision (Rare (<0.1%))
Report any sudden change in vision to your eye doctor immediately.

⚠️ Rare Side Effects

Eyelid dermatitis
Stop using the medicine and consult your eye doctor if you develop a rash or swelling around the eyelids.
Punctate keratitis
This may cause eye discomfort and light sensitivity. Contact your eye doctor for evaluation.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other eye drops Moderate
Contact lenses Moderate

🚨 Major Interactions

  • Other topical ophthalmic medications

⚡ Moderate Interactions

  • Contact lenses

🍷 Alcohol Interaction

No specific interaction between this medicine and alcohol is established from the available information. However, alcohol can affect eye pressure and overall health, so moderation is advised.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity or allergy to netarsudil or any component of this medicine","Active eye infection or inflammation not evaluated by a doctor","Use in children under 18 years of age is not established"]

⚠️ Warnings & Precautions

["This medicine is for topical ophthalmic use only. Do not inject or swallow it.","Remove contact lenses before use and wait at least 15 minutes before reinserting them.","If you develop eye pain, redness, or blurred vision that worsens, contact your eye doctor promptly.","Do not touch the dropper tip to your eye or any surface to avoid contamination.","Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep this medicine out of reach of children.","Do not use this medicine after the expiry date printed on the bottle."]

🤱 Lactation Safety

It is not known whether this medicine is excreted in human breast milk. Because many medicines are excreted in breast milk, caution should be exercised when using this medicine during breastfeeding. Consult your doctor.

💊 Overdose Management

Overdose with this medicine is unlikely because it is applied topically to the eye. If you accidentally swallow the solution, rinse your mouth with water and contact a poison control center or emergency room. If you instill too many drops in the eye, rinse the eye with clean water and contact your eye doctor if you experience discomfort.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Wash your hands thoroughly before and after using this medicine. Tilt your head back, pull down your lower eyelid to form a small pocket, and squeeze one drop into the pocket without letting the dropper touch your eye or any surface. Close your eye gently for one to two minutes and press the inner corner of your eye near the nose to help the medicine stay in the eye and reduce systemic absorption. If you wear contact lenses, remove them before instilling the drops and wait at least 15 minutes before putting them back in. Do not use this medicine if the solution looks cloudy or has particles in it. Keep the bottle tightly closed when not in use and store it as directed. Do not share your eye drops with anyone else, even if they have similar symptoms. Tell your eye doctor about all other eye medicines you use, because spacing them at least 5 minutes apart is often recommended.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially eye redness and discomfort. Regular monitoring by an eye doctor is important. No specific dose adjustment is required based on age alone, but your doctor will consider your overall health and other medications.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, discuss this medicine with your eye doctor and obstetrician. There are no adequate studies of this medicine in pregnant women. Your doctor will weigh the benefits of controlling eye pressure against potential risks to the baby.

🏥 Post-Surgery Considerations

If you have eye surgery, inform your surgeon that you are using this medicine. You may need to stop using it temporarily before or after surgery. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

No specific precautions are established for dental procedures while using this medicine. However, inform your dentist about all medicines you use, including eye drops.

💚 Lifestyle Tips for Better Results

🏃
Attend all scheduled eye appointments to monitor your eye pressure and optic nerve health.
🥗
Maintain a healthy lifestyle with regular exercise and a balanced diet to support overall eye health.
😴
Avoid rubbing your eyes vigorously, as this can increase eye pressure.
💧
Wear sunglasses outdoors to protect your eyes from UV rays and reduce glare.
🧘
Limit caffeine intake if you notice it increases your eye pressure.
🌞
Get adequate sleep and manage stress, as stress can affect eye pressure.
🚭
Follow your eye doctor's instructions for using other eye medications.

🏋️ Exercise Considerations

Regular exercise is generally safe while using this medicine. However, avoid activities that involve inverted positions or heavy straining, such as certain yoga poses or weightlifting, as these can temporarily increase eye pressure. Consult your eye doctor before starting any new exercise routine.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Include foods high in omega-3 fatty acids, such as fish and flaxseed.
Stay well hydrated by drinking plenty of water.
Limit caffeine and alcohol, as they may affect eye pressure.
Avoid processed foods and excess salt.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision right after instillation. Wait until your vision is clear before driving or operating machinery. Otherwise, it should not significantly affect your daily work or activities. If you experience persistent eye redness or discomfort, inform your employer if your work involves visual tasks.

🛑 When to Stop This Medicine

Do not stop using this medicine without consulting your eye doctor. If you experience severe side effects or an allergic reaction, stop using it and seek medical attention immediately. Your eye doctor may adjust or change your treatment based on your response and side effects.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well tolerated. Some patients may develop corneal deposits called cornea verticillata, which usually do not affect vision and resolve after stopping the medicine. Regular eye examinations are important to monitor eye pressure, corneal health, and optic nerve status. If you notice any changes in vision or persistent eye discomfort, consult your eye doctor. Do not stop the medicine without medical advice, as uncontrolled eye pressure can lead to permanent vision loss.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Laser trabeculoplasty

A laser procedure that can improve aqueous humor drainage and lower eye pressure. It may be an alternative or adjunct to eye drops.

Evidence: Well-established
Other classes of eye drops

Prostaglandin analogs, beta-blockers, alpha-2 agonists, and carbonic anhydrase inhibitors are other options for lowering eye pressure.

Evidence: Well-established
Glaucoma surgery

Surgical procedures such as trabeculectomy or drainage implants may be considered when medications are not effective.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interaction between this medicine and vaccines is established from the available information. You can receive vaccinations as recommended by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature between 15°C and 30°C

❌ DON'T

Do not freeze or refrigerate unless instructed

✅ DO

Keep the bottle tightly closed when not in use

❌ DON'T

Do not leave the cap off for long periods

✅ DO

Protect from direct sunlight and excessive heat

❌ DON'T

Do not store in a hot car or near a stove

✅ DO

Keep out of reach of children

❌ DON'T

Do not share your eye drops with others

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your eye doctor, especially for international travel. Keep the bottle in your carry-on luggage to avoid extreme temperatures in checked baggage. Store it at room temperature and protect it from direct sunlight. If you are crossing time zones, continue using the medicine once daily in the evening according to your new local time, unless your eye doctor advises otherwise. Refill your prescription before traveling to avoid running out.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with open-angle glaucoma
He was prescribed this medicine once daily in the evening after his eye pressure remained high on another drop. Within a few weeks, his eye pressure dropped to a safer range. He noticed some eye redness initially, but it became less bothersome over time. He emphasized the importance of not missing doses and keeping regular eye appointments.
💡 Lesson: Consistent daily use and regular monitoring are key to controlling eye pressure and protecting vision.
👤 A 65-year-old woman with ocular hypertension
She started this medicine after her eye doctor found elevated pressure during a routine exam. She was initially worried about side effects but found that pressing the inner corner of her eye after instillation helped reduce the medicine's taste and systemic absorption. Her eye pressure remained well controlled at follow-up visits.
💡 Lesson: Proper instillation technique, including punctal occlusion, can improve comfort and reduce systemic side effects.

💬 Questions Patients Often Ask

Q: How long does it take for this medicine to work?

A: This medicine starts lowering eye pressure within 2 to 4 hours after instillation, and the effect lasts about 24 hours. However, it may take a few weeks of regular use before your eye doctor can measure a consistent reduction in pressure.

Q: Can I use this medicine if I wear contact lenses?

A: You should remove your contact lenses before instilling this medicine and wait at least 15 minutes before putting them back in. This medicine can be absorbed by soft contact lenses and may cause irritation.

Q: What should I do if I accidentally swallow this medicine?

A: This medicine is for eye use only. If swallowed, rinse your mouth with water and contact a poison control center or emergency room immediately.

Q: Can I stop using this medicine if my eye pressure is normal?

A: No, you should not stop using this medicine without consulting your eye doctor. Even if your eye pressure is normal, stopping the medicine can cause the pressure to rise again and potentially damage your optic nerve.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine long-term?
  • Will this medicine affect my vision permanently?
  • Can I drive after using this medicine?
  • Does this medicine interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while using this medicine?
  • Is this medicine safe for my kidneys?
  • Can I use this medicine with other eye drops?

🔄 Substitutes for netalo eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure glaucoma permanently.
    Fact: This medicine controls eye pressure but does not cure glaucoma. You need to use it regularly and monitor your eyes for life.
  • Myth: Eye redness means the medicine is not working.
    Fact: Redness is a common side effect and does not mean the medicine is ineffective. However, report severe or painful redness to your doctor.
  • Myth: You can stop using this medicine once your eye pressure is normal.
    Fact: Stopping this medicine can cause eye pressure to rise again and damage the optic nerve. Always consult your eye doctor before stopping.

🔄 Alternative Options

Generic Alternatives

  • Netarsudil ophthalmic solution 0.02%

Brand Alternatives

  • Netalo Eye Drop

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (netarsudil 0.02%)","class":"Rho kinase inhibitor","frequency":"Once daily","common_side_effects":"Eye redness, corneal deposits"},{"medicine":"Latanoprost","class":"Prostaglandin analog","frequency":"Once daily","common_side_effects":"Eye redness, eyelash growth, iris color change"},{"medicine":"Timolol","class":"Beta-blocker","frequency":"Twice daily","common_side_effects":"Eye irritation, reduced heart rate, fatigue"}]

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