neoquine 40mg injection - Chloroquine (40mg) medicine

Emquin 40mg Injection: Complete Medicine Guide

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🏭 Neon Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 31, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for malaria; established for autoimmune conditions.
Reviewed by
SaathiMed Expert Panel | Oct 31, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Palpitations or irregular heartbeat
  • Fainting or severe dizziness
  • Difficulty breathing or chest pain
  • Sudden vision changes or blurred vision
  • Severe skin rash or blistering
  • Yellowing of eyes or skin
  • Unusual bleeding or bruising
  • Seizures or confusion

If experiencing severe symptoms, call emergency services immediately.

What is neoquine 40mg injection used for?

This medicine is a chloroquine injection used to treat malaria and certain autoimmune diseases. It works by killing malaria parasites and modulating the immune system. It is given by a healthcare professional and requires careful monitoring.

  • Generic Name: Chloroquine (40mg)
  • Manufacturer: Neon Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 neoquine 40mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा क्लोरोक्वीन का इंजेक्शन है, जिसका उपयोग मलेरिया और कुछ ऑटोइम्यून बीमारियों के इलाज के लिए किया जाता है। यह मलेरिया परजीवी को मारती है और प्रतिरक्षा प्रणाली को नियंत्रित करती है। यह इंजेक्शन के रूप में डॉक्टर द्वारा दिया जाता है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, सिरदर्द, चक्कर आना और धुंधली दृष्टि शामिल हैं। गंभीर दुष्प्रभावों में हृदय की अनियमितता, निम्न रक्तचाप, और दृष्टि में स्थायी परिवर्तन हो सकते हैं। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। इसे स्वयं न लें। अपने डॉक्टर को अपनी सभी दवाओं और स्वास्थ्य स्थितियों के बारे में बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। शराब का सेवन न करें। नियमित जांच कराते रहें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 neoquine 40mg injection Uses & Benefits

[{"condition":"Malaria (chloroquine-sensitive)","description":"Used for the treatment of uncomplicated and severe malaria caused by chloroquine-sensitive Plasmodium species, especially when oral therapy is not possible.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"May be used as a disease-modifying antirheumatic drug in selected patients when other treatments are unsuitable.","evidence":"Established"},{"condition":"Systemic lupus erythematosus","description":"Used for skin and joint manifestations of lupus, particularly when oral therapy is not feasible.","evidence":"Established"},{"condition":"Extraintestinal amebiasis","description":"Occasionally used as an adjunct in the treatment of invasive amebiasis, though other agents are preferred.","evidence":"Limited"}]

Off-label uses: [{"condition":"Porphyria cutanea tarda","description":"Sometimes used off-label to reduce porphyrin levels, but this is not a standard indication.","evidence":"Limited"},{"condition":"Sarcoidosis","description":"Rarely used off-label for cutaneous sarcoidosis, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Malaria

Also treats: Rheumatoid arthritis, Systemic lupus erythematosus, Extraintestinal amebiasis

📋 Drug Information

Generic Name(s)Chloroquine (40mg)
Brand Nameneoquine 40mg injection
ManufacturerNeon Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassAntimalarial- Aminoquinolines
Route of AdministrationParenteral (intramuscular or intravenous)
StorageStore at controlled room temperature (15-30°C). Protect from light. Do not freeze. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineChloroquine is recommended by WHO for the treatment of malaria caused by chloroquine-sensitive Plasmodium species. However, due to widespread resistance, its use is limited to areas where sensitivity is confirmed.
ICMR GuidelineICMR guidelines recommend chloroquine for the treatment of malaria in areas where the parasite is known to be sensitive. It is not recommended for falciparum malaria in most parts of India due to resistance.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always administer this medicine in a setting where cardiac monitoring is available.
2
Avoid rapid intravenous injection to prevent hypotension and arrhythmias.
3
Perform a baseline ECG before administration in patients with cardiac risk factors.
4
Monitor renal and hepatic function periodically during treatment.
5
For long-term use, schedule regular ophthalmologic examinations.
6
Educate patients about the importance of reporting visual changes immediately.
7
Use with caution in patients with G6PD deficiency and monitor for hemolysis.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with chills
This medicine is used for malaria, which often presents with fever and chills.
Likely Use
✅
Joint pain and swelling
May be used for autoimmune conditions like rheumatoid arthritis.
Likely Use
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing intramuscular or intravenous administration, chloroquine is rapidly and completely absorbed. The bioavailability is high, approaching 100% for intravenous administration. After intramuscular injection, peak plasma concentrations are typically reached within 1 to 2 hours.
DistributionChloroquine has a large volume of distribution, extensively binding to tissues such as liver, spleen, kidney, lung, and melanin-containing tissues. It crosses the placenta and is excreted in breast milk. The drug accumulates in erythrocytes infected with malaria parasites.
Protein BindingApproximately 50-60% of chloroquine is bound to plasma proteins, primarily albumin and alpha-1-acid glycoprotein.
MetabolismChloroquine is partially metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C8 and CYP3A4, to active metabolites including desethylchloroquine and bisdesethylchloroquine.
Half-LifeThe elimination half-life of chloroquine is long, ranging from 20 to 60 days, with a terminal half-life of up to 60 days due to extensive tissue binding.
ExcretionChloroquine and its metabolites are primarily excreted in the urine. Approximately 10-20% of the administered dose is excreted unchanged in the urine, with the remainder as metabolites. Renal excretion is enhanced by acidification of urine.
BioavailabilityBioavailability is high, approximately 89% for oral administration, but this medicine is given parenterally, so bioavailability is essentially 100%.
Onset of ActionThe onset of action for antimalarial effect is typically within 1 to 2 hours after intravenous administration, with clinical improvement in fever and parasitemia within 24 to 48 hours.
Peak Plasma TimePeak plasma concentrations are reached within 1 to 2 hours after intramuscular injection and immediately after intravenous administration.
Duration of ActionThe antimalarial effect persists for several days due to the long half-life and tissue accumulation. The immunomodulatory effects may take weeks to manifest.

How It Works

Chloroquine is a weak base that accumulates in the acidic food vacuole of the malaria parasite. Inside the vacuole, it becomes protonated and cannot diffuse back out, leading to an increase in pH. This alkalinization interferes with the parasite's ability to detoxify heme, a byproduct of hemoglobin digestion. The toxic heme accumulates and causes oxidative damage to the parasite's membranes, ultimately leading to parasite death. In autoimmune conditions, chloroquine is thought to modulate immune responses by inhibiting antigen presentation and reducing the production of pro-inflammatory cytokines, although the exact mechanism is not fully understood.

Mechanism Steps

1
Accumulation in food vacuole: Chloroquine diffuses into the parasite's food vacuole and becomes protonated due to the acidic environment, trapping it inside.
2
Inhibition of heme detoxification: The protonated chloroquine interferes with the conversion of toxic heme into inert hemozoin, causing heme to accumulate.
3
Oxidative damage: Accumulated heme generates free radicals that damage the parasite's membranes and other cellular components.
4
Parasite death: The oxidative stress and disruption of essential processes lead to the death of the malaria parasite.

💡 How to Take neoquine 40mg injection

Strength: 40 mg injection

1This medicine is given by a healthcare professional as an intramuscular or intravenous injection.
2Do not attempt to self-administer.
3The injection site will be cleaned before administration.
4For intravenous use, the injection may be given slowly to avoid side effects.
5Report any immediate discomfort or unusual symptoms to the healthcare provider.

Dosage Information

Adult DosageThe dosage of this medicine must be individualized by a qualified clinician based on the indication, severity of disease, age, weight, renal and hepatic function. For malaria treatment, a typical regimen might involve an initial dose followed by additional doses at specified intervals, but exact dosing must be determined by the treating physician. For autoimmune conditions, lower doses are used. This medicine should only be administered by a healthcare professional.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to side effects, especially cardiac and ocular toxicity. Dose should be individualized by a clinician, and renal function should be monitored.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a clinician for individualized dosing.
Hepatic ImpairmentDose adjustment may be required in patients with hepatic impairment. Consult a clinician for individualized dosing.
Maximum Daily DoseNot established from the available information. The maximum daily dose must be determined by a qualified clinician based on the indication and patient factors.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Grapefruit juice
Avoid
May increase chloroquine levels and toxicity.
Alcohol
Avoid
May increase risk of liver toxicity and cardiac effects.

⏰ What to Do If You Miss a Dose

📌 If you miss a scheduled dose
→ Contact your healthcare provider immediately.
💡 Do not attempt to self-administer.

⚠️ Side Effects of neoquine 40mg injection

✅ Common Side Effects

Nausea (Common (5-10%))
Usually resolves on its own. If persistent, inform your doctor.
Vomiting (Common (5-10%))
Stay hydrated. If severe, consult your doctor.
Headache (Common (5-10%))
Rest and take paracetamol if needed, but consult your doctor first.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal.
Blurred vision (Uncommon (1-5%))
Report to your doctor if it persists or worsens.

🚨 Serious Side Effects

Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, fainting, or chest pain.
Severe hypotension (Rare (<0.1%))
Requires immediate medical intervention.
Retinopathy (Rare with short-term use, more common with prolonged use)
Regular eye exams are necessary for long-term therapy. Report any visual changes immediately.
Bone marrow suppression (Rare (<0.1%))
Report unusual bleeding, bruising, or signs of infection.
Seizures (Rare (<0.1%))
Seek emergency medical care immediately.

⚠️ Rare Side Effects

Severe skin reactions (e.g., Stevens-Johnson syndrome)
Seek immediate medical attention if you develop a rash, blisters, or peeling skin.
Hepatotoxicity
Report yellowing of skin or eyes, dark urine, or severe abdominal pain.
Neuropsychiatric effects
Report mood changes, confusion, or hallucinations to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Amiodarone Major
Mefloquine Major
Digoxin Major
Metformin Moderate
Cimetidine Moderate
Rifampicin Moderate
Antacids Minor
Kaolin Minor
Alcohol Moderate
Grapefruit juice Moderate

🚨 Major Interactions

  • Amiodarone
  • Mefloquine
  • Digoxin

⚡ Moderate Interactions

  • Metformin
  • Cimetidine
  • Rifampicin

🍷 Alcohol Interaction

Alcohol should be avoided while receiving this medicine. Concurrent use may increase the risk of liver toxicity and cardiac arrhythmias. It may also worsen side effects such as dizziness and nausea.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chloroquine or any component of the formulation","Pre-existing retinopathy or visual field changes","Severe hepatic impairment","Severe renal impairment (unless under specialist supervision)","History of epilepsy","Porphyria"]

⚠️ Warnings & Precautions

["Administer with caution in patients with cardiac disease, as it may cause arrhythmias.","Avoid rapid intravenous injection to prevent hypotension and cardiac toxicity.","Use with caution in patients with G6PD deficiency due to risk of hemolysis.","May exacerbate psoriasis.","May cause visual disturbances; caution when driving or operating machinery.","Long-term use requires regular ophthalmologic examinations.","Not recommended for malaria prophylaxis in areas with chloroquine-resistant malaria."]

🤱 Lactation Safety

Chloroquine is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose of chloroquine is life-threatening and requires immediate medical attention. Symptoms include headache, drowsiness, visual disturbances, cardiovascular collapse, convulsions, and cardiac arrest. Treatment is supportive and may include gastric lavage (if oral ingestion and recent), activated charcoal, intravenous fluids, vasopressors, and mechanical ventilation. Sodium bicarbonate may be used to treat cardiac toxicity. Hemodialysis or hemoperfusion may be considered but are of limited value due to extensive tissue binding.

⏰ Missed Dose

Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, contact your healthcare provider for guidance. Do not attempt to self-administer.

Additional Safety Advice

General Safety

This medicine must be administered only by a healthcare professional in a monitored setting. Do not self-administer. Inform your doctor about all medications you are taking, especially other antimalarials, cardiac drugs, and drugs that affect liver enzymes. Avoid alcohol during treatment as it may increase the risk of liver toxicity. If you are pregnant or breastfeeding, discuss the risks and benefits with your doctor before receiving this medicine. Regular eye examinations are recommended if this medicine is used for prolonged periods. Report any muscle weakness, visual disturbances, or skin rash immediately. Keep all follow-up appointments to monitor your response and any potential side effects.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of cardiac, ocular, and renal toxicity. Dose should be individualized, and renal function should be monitored closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before receiving this medicine. Chloroquine is generally considered safe in pregnancy when used for malaria, but the risks and benefits should be weighed.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are receiving this medicine, as it may interact with anesthetic agents and affect cardiac function.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding or interact with medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Use mosquito nets and repellents to prevent malaria.
🥗
Avoid alcohol while on this medicine.
😴
Stay hydrated to help kidney function.
💧
Report any visual changes immediately.
🧘
Follow up regularly with your doctor for monitoring.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience dizziness or fatigue. Consult your doctor before resuming intense physical activity.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Avoid grapefruit juice.
Limit alcohol consumption.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness and blurred vision, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is administered in a healthcare setting, so you may need to take time off work for treatment.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects, seek immediate medical attention. Your doctor will decide if and when to stop treatment based on your response and any adverse effects.

📅 Long-Term Use Effects

Long-term use of chloroquine can lead to irreversible retinopathy, which may progress even after stopping the drug. Regular ophthalmologic examinations are essential. Other long-term effects include myopathy, neuropathy, and skin pigmentation. Monitoring of liver and kidney function is also recommended.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Artemisinin-based combination therapy (ACT)

For malaria, ACTs are often preferred, especially for falciparum malaria.

Evidence: Well-established
Hydroxychloroquine

An oral alternative for autoimmune conditions with a better safety profile.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are receiving live vaccines, consult your doctor as chloroquine may affect immune response.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

If you are prescribed this medicine for travel, carry it in its original packaging with a copy of your prescription. Since it is an injection, it must be administered by a healthcare professional. Ensure you have access to medical facilities at your destination. Store it at room temperature and protect from light. Check customs regulations for carrying injectable medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with severe malaria unable to take oral medication
He was admitted with high fever and vomiting. He received this medicine intravenously under supervision. His fever subsided within 48 hours, and he was switched to oral therapy. He experienced mild nausea but no serious side effects.
💡 Lesson: Parenteral chloroquine is effective for severe malaria when oral therapy is not possible, but requires monitoring.
👤 A 50-year-old woman with rheumatoid arthritis who could not tolerate oral methotrexate
She was started on this medicine as an alternative. Over several weeks, her joint pain and swelling improved. She was monitored with regular eye exams and blood tests. She remained stable without major side effects.
💡 Lesson: Chloroquine injection can be an option for autoimmune conditions when oral therapy is not feasible, but long-term monitoring is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The antimalarial effect begins within 1-2 hours after injection, with clinical improvement in fever and parasitemia within 24-48 hours.

Q: Can I take this medicine at home?

A: No, this medicine must be administered by a healthcare professional in a monitored setting.

Q: What are the serious side effects I should watch for?

A: Serious side effects include cardiac arrhythmias, severe hypotension, visual changes, and seizures. Seek immediate medical attention if you experience these.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine if I have kidney disease?
  • How often should I get eye exams while on this medicine?
  • Is it safe to take this medicine with other antimalarials?
  • Can I drive after receiving this injection?
  • What should I do if I experience side effects?
  • How long will I need to stay in the hospital after this injection?

🔄 Substitutes for neoquine 40mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Chloroquine injection can be self-administered at home.
    Fact: This medicine must only be given by a healthcare professional in a monitored setting.
  • Myth: Chloroquine is safe for everyone.
    Fact: It is contraindicated in certain conditions like retinopathy, epilepsy, and porphyria.
  • Myth: Chloroquine injection is the first choice for all malaria.
    Fact: Due to resistance, it is only used for chloroquine-sensitive malaria.

🔄 Alternative Options

Generic Alternatives

  • Chloroquine injection (generic)

Brand Alternatives

  • Emquin 40mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Chloroquine","class":"4-aminoquinoline","route":"Parenteral","main_use":"Malaria, autoimmune diseases"},{"medicine":"Hydroxychloroquine","class":"4-aminoquinoline","route":"Oral","main_use":"Autoimmune diseases, malaria"},{"medicine":"Mefloquine","class":"Quinoline methanol","route":"Oral","main_use":"Malaria prophylaxis and treatment"}]

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