Chloroquin 40mg Injection
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
What is chloroquin 40mg injection used for?
This medicine contains Chloroquine (40mg) and is used to treat OPHTHAL. Inhibits heme polymerase in malarial parasites, leading to accumulation of toxic heme; also has anti. Always consult your doctor before use.
- Generic Name: Chloroquine
- Manufacturer: Zydus Cadila
- Form: Allopathy
- Pregnancy Category: Category A
- Prescription Required: Yes
💊 chloroquin 40mg injection Uses & Benefits
Malaria (treatment and prophylaxis), amebic hepatitis, lupus erythematosus, rheumatoid arthritis (off-label).
Off-label uses: Rheumatoid arthritis, lupus erythematosus, sarcoidosis, porphyria cutanea tarda.
📋 Drug Information
| Generic Name(s) | Chloroquine |
| Brand Name | Amloquin DS 250mg Tablet |
| Manufacturer | Zydus Cadila |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Antimalarial- Aminoquinolines |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C); protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Inhibits heme polymerase in malarial parasites, leading to accumulation of toxic heme; also has anti-inflammatory and immunosuppressive effects.
Mechanism Steps
💡 How to Take chloroquin 40mg injection
Follow your doctor's prescription exactly.
⚠️ Side Effects of chloroquin 40mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | Increased risk of cardiotoxicity |
| Cimetidine | Major | Increased chloroquine levels |
| Cyclosporine | Major | Increased cyclosporine levels |
| Digoxin | Major | Increased digoxin levels |
| Mefloquine | Major | Increased risk of seizures |
| Penicillamine | Major | Increased risk of hematologic toxicity |
| Tamoxifen | Major | Increased risk of retinopathy |
| Antacids | Moderate | Decreased absorption of chloroquine |
| Kaolin | Moderate | Decreased absorption of chloroquine |
| Magnesium trisilicate | Moderate | Decreased absorption of chloroquine |
| Corticosteroids | Moderate | Increased risk of immunosuppression |
| Insulin | Moderate | Increased hypoglycemic effect |
| Antidiabetic agents | Moderate | Increased hypoglycemic effect |
| Alcohol | Minor | Increased hepatotoxicity risk |
| Tetracyclines | Minor | Decreased tetracycline absorption |
| Chlorpromazine | Minor | Increased risk of extrapyramidal symptoms |
🚨 Major Interactions
- Amiodarone
- Cimetidine
- Cyclosporine
- Digoxin
- Mefloquine
- Penicillamine
- Tamoxifen
⚡ Moderate Interactions
- Antacids
- Kaolin
- Magnesium trisilicate
- Corticosteroids
- Insulin
- Antidiabetic agents
🍷 Alcohol Interaction
May increase risk of hepatotoxicity; avoid excessive alcohol.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to chloroquine or 4-aminoquinolines; retinal or visual field changes; porphyria; myasthenia gravis; G6PD deficiency (caution).
🤱 Lactation Safety
Excreted in breast milk; caution advised.
💊 Overdose Management
Immediate gastric lavage; activated charcoal; supportive care; monitor for cardiac arrhythmias, seizures, and hypotension.
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.
🔄 Substitutes for chloroquin 40mg injection
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kinphos 40mg injectionAlembic Pharmaceuticals Ltd ₹8.75 SAME PRICE
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Troyquin DS 40mg TabletTroikaa Pharmaceuticals Ltd ₹12.07 37.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.