Neopriga-nt Tablet Sr: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Seizures or convulsions
- Severe allergic reaction with swelling of the face, lips, or throat
- Difficulty breathing or chest pain
- Yellowing of the eyes or skin, or dark urine
- Severe abdominal pain
- Thoughts of self-harm or suicide
- Severe headache with visual changes
- Sudden increase in blood pressure
If experiencing severe symptoms, call emergency services immediately.
What is neopriga-nt tablet sr used for?
This medicine is a prescription weight-management tablet that combines naltrexone and bupropion. It is used in adults with obesity or overweight with weight-related conditions, alongside a reduced-calorie diet and exercise. It works by reducing appetite and food cravings. It is not suitable for everyone and must be used under medical supervision.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 neopriga-nt tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा मोटापे और अधिक वजन के इलाज के लिए इस्तेमाल की जाती है, खासकर उन वयस्कों में जिनका बॉडी मास इंडेक्स 30 या उससे अधिक है, या जिनका बॉडी मास इंडेक्स 27 या उससे अधिक है और साथ में टाइप 2 डायबिटीज, हाई ब्लड प्रेशर या हाई कोलेस्ट्रॉल जैसी समस्या है। यह दवा भूख और खाने की तलब को कम करने में मदद करती है और शरीर के ऊर्जा खर्च को थोड़ा बढ़ाती है। इसे कम कैलोरी वाले आहार और नियमित व्यायाम के साथ ही लेना चाहिए। यह दवा डॉक्टर के प्रिस्क्रिप्शन के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, कब्ज, सिरदर्द, उल्टी, चक्कर आना, मुंह सूखना, नींद न आना और दस्त शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ हफ्तों में ठीक हो जाते हैं। कुछ गंभीर दुष्प्रभाव भी हो सकते हैं जैसे दौरे पड़ना, गंभीर एलर्जी, लिवर की समस्या, और मूड में बदलाव या आत्महत्या के विचार। अगर आपको सीने में दर्द, सांस लेने में तकलीफ, चेहरे या गले में सूजन, आंखों या त्वचा का पीला पड़ना, या खुद को नुकसान पहुंचाने के विचार आते हैं, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर सुबह में एक बार भोजन के साथ। गोली को पूरा निगलें, चबाएं या तोड़ें नहीं। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो यह दवा न लें। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर दर्द निवारक दवाएं, अवसादरोधी दवाएं और ब्लड प्रेशर की दवाएं। इस दवा के साथ शराब न लें। नियमित रूप से अपना ब्लड प्रेशर, हृदय गति, मूड और लिवर फंक्शन की जांच कराएं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। सर्जरी या दंत चिकित्सा से पहले अपने डॉक्टर को इस दवा के बारे में बताएं।
💊 neopriga-nt tablet sr Uses & Benefits
[{"condition":"Chronic weight management in obesity","description":"This medicine is used as an adjunct to a reduced-calorie diet and increased physical activity for long-term weight management in adults with a body mass index of 30 kg/m2 or greater.","evidence":"Well-established"},{"condition":"Chronic weight management in overweight with weight-related conditions","description":"This medicine is used for weight management in adults with a body mass index of 27 kg/m2 or greater who also have at least one weight-related condition such as type 2 diabetes, high blood pressure, or high cholesterol.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Binge eating disorder","description":"This medicine has been studied as a possible treatment for binge eating disorder in some patients, but it is not approved for this use.","evidence":"Limited"},{"condition":"Food addiction and craving reduction","description":"Some clinicians may consider this medicine for patients with strong food cravings or addictive eating patterns, although this is not an approved indication.","evidence":"Limited"}]
Primary treatment for: Obesity and overweight with weight-related conditions
Also treats: Type 2 diabetes, High blood pressure, High cholesterol, Obstructive sleep apnoea
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | neopriga-nt tablet sr |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F and 86°F). Keep it in the original container, tightly closed, and protect it from moisture and direct sunlight. Do not store it in the bathroom or near the kitchen sink. Keep this medicine out of the reach of children and pets. |
| Shelf Life | Not established from the available information. Check the expiry date printed on the pack and do not use the medicine after that date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines naltrexone, an opioid receptor antagonist, with bupropion, a norepinephrine and dopamine reuptake inhibitor. Together, these two ingredients act on the appetite-regulation and reward pathways in the brain. Bupropion increases the availability of dopamine and norepinephrine, which can reduce appetite and increase energy expenditure, while naltrexone blocks opioid receptors that are involved in the rewarding effects of food. The combination is thought to work synergistically to reduce food intake and help patients adhere to a reduced-calorie diet.
Mechanism Steps
💡 How to Take neopriga-nt tablet sr
Strength: Sustained-release tablet containing naltrexone and bupropion. The exact strength is not specified in the available information. Take only the strength prescribed by your doctor.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken once daily in the morning with food. The dose may be increased gradually over several weeks as directed by your doctor to reduce the risk of side effects. The maximum recommended daily dose is one tablet of the prescribed strength. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially dizziness, falls, and changes in blood pressure. Your doctor may start with a lower dose and monitor you more closely. Dose must be individualized by a qualified clinician based on age, kidney and liver function, and other medicines you are taking. |
| Renal Impairment | Not established from the available information. This medicine should be used with caution in patients with kidney disease. Your doctor may adjust the dose or monitor your kidney function more closely. |
| Hepatic Impairment | This medicine is not recommended in patients with severe liver disease. In patients with mild to moderate liver disease, your doctor may start with a lower dose and monitor liver function closely. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet of the prescribed strength, taken once daily. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of neopriga-nt tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Opioid painkillers | Major | |
| MAOIs | Major | |
| Antidepressants | Major | |
| Antipsychotics | Major | |
| Blood pressure medicines | Moderate | |
| Diabetes medicines | Moderate | |
| CYP2D6 substrates | Moderate | |
| Alcohol | Moderate | |
| Caffeine | Minor | |
| Nicotine replacement therapy | Minor |
🚨 Major Interactions
- Opioid painkillers (e.g., morphine, codeine, tramadol)
- Monoamine oxidase inhibitors (MAOIs)
- Antidepressants (SSRIs, SNRIs, tricyclics)
- Antipsychotics
⚡ Moderate Interactions
- Blood pressure medicines
- Diabetes medicines
- CYP2D6 substrates (e.g., metoprolol, tamoxifen, some antidepressants)
- Alcohol
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase the risk of seizures and liver problems. Alcohol can also worsen some of the side effects such as dizziness, drowsiness, and mood changes. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy or planning to become pregnant","Breastfeeding","Uncontrolled high blood pressure","History of seizures","Opioid dependence or current use of opioid painkillers","Severe liver disease","Chronic opioid use for pain management","Known allergy to naltrexone, bupropion, or any component of this medicine","Use of MAOIs within the last 14 days","Eating disorders such as anorexia nervosa or bulimia nervosa"]
⚠️ Warnings & Precautions
["This medicine can cause seizures, especially in people with a history of seizures, head injury, or alcohol withdrawal. Tell your doctor if you have any of these conditions.","This medicine can increase blood pressure and heart rate. Your doctor should check your blood pressure before starting treatment and monitor it regularly.","This medicine can cause mood changes, depression, or suicidal thoughts. Contact your doctor immediately if you notice any changes in your mood or behaviour.","This medicine can cause liver injury. Report symptoms such as yellowing of the eyes or skin, dark urine, or severe abdominal pain to your doctor.","This medicine can block the effects of opioid painkillers. Inform your doctor or surgeon that you are taking this medicine before any surgery or procedure.","Do not stop this medicine suddenly without talking to your doctor, as this can cause withdrawal symptoms or worsen underlying conditions.","This medicine is a controlled substance and should be used only under the supervision of a qualified healthcare professional."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because of the potential for serious side effects in a breastfed infant, this medicine is not recommended during breastfeeding. Discuss alternative feeding options with your doctor.
💊 Overdose Management
If you suspect an overdose of this medicine, seek emergency medical attention immediately. Symptoms of overdose may include severe nausea, vomiting, dizziness, fainting, seizures, hallucinations, rapid heartbeat, and difficulty breathing. There is no specific antidote for this medicine, and treatment is supportive and symptomatic. Contact your local poison control centre or go to the nearest emergency department. Take the medicine container with you so that the medical team knows exactly what you have taken.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily in the morning with food, and swallow the tablet whole without crushing, chewing, or splitting it, because it is a sustained-release formulation. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding, and use a reliable method of contraception while you are on treatment. Tell your doctor about all other medicines you take, especially opioid painkillers, antidepressants, antipsychotics, blood-pressure medicines, and medicines for diabetes, because this product can interact with them. Avoid alcohol while taking this medicine, as alcohol can increase the risk of seizures and liver problems. Have your blood pressure, heart rate, mood, and liver function checked regularly as advised by your clinician. Do not drive or operate heavy machinery until you know how this medicine affects you, because it can cause dizziness or blurred vision. If you are scheduled for surgery or a dental procedure, inform the surgeon, anaesthetist, or dentist that you are taking this medicine, because it can interfere with opioid pain relief. Keep this medicine out of the reach of children and store it at room temperature away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to the side effects of this medicine, especially dizziness, falls, and changes in blood pressure. Your doctor may start with a lower dose and monitor you more closely. Regular check-ups for blood pressure, heart rate, liver function, and mental health are important.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are planning to become pregnant. Weight loss is not recommended during pregnancy. If you are planning pregnancy, talk to your doctor about stopping this medicine and using a safe alternative. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anaesthetist that you are taking this medicine before any surgery. This medicine can block the effects of opioid painkillers, which may affect pain management after surgery. Your doctor may advise you to stop the medicine temporarily before surgery. Follow your doctor's instructions carefully.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure. This medicine can interact with opioid painkillers that may be used for dental pain, making them less effective. Your dentist may need to adjust your pain management plan.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged while taking this medicine, but start slowly and gradually increase the intensity. If you experience dizziness, shortness of breath, or chest pain during exercise, stop and seek medical advice. Stay well hydrated, especially during hot weather or intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, blurred vision, or trouble sleeping, which can affect your ability to drive or operate heavy machinery. Avoid driving or operating machinery until you know how this medicine affects you. If your work involves shift work or irregular hours, discuss with your doctor how to take your dose consistently. The medicine may also cause mood changes, so monitor your mental health and seek support if needed.
🛑 When to Stop This Medicine
Do not stop taking this medicine without first talking to your doctor. Your doctor may recommend stopping if you do not achieve adequate weight loss after a certain period, if you develop serious side effects, or if you become pregnant. If you need to stop, your doctor will advise you on how to taper the dose safely to avoid withdrawal symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine may be associated with ongoing weight loss and improvement in weight-related conditions such as diabetes and high blood pressure. However, it can also cause persistent side effects such as nausea, constipation, and mood changes. Regular monitoring of blood pressure, heart rate, liver function, and mental health is recommended. If you stop the medicine, weight regain is common unless you maintain lifestyle changes. Your doctor will decide how long you should take this medicine based on your response and overall health.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A reduced-calorie diet and regular physical activity are the foundation of weight management and can be effective on their own.
Evidence: Well-establishedCounselling and behavioural therapy can help address eating habits and emotional triggers.
Evidence: Well-establishedOther prescription medicines such as orlistat, liraglutide, or semaglutide may be considered if this medicine is not suitable.
Evidence: Well-establishedFor severe obesity, bariatric surgery may be an option when other treatments have not worked.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a letter from your doctor stating that you are taking this medicine for a medical condition. If you are crossing time zones, continue taking your dose in the morning according to your usual routine, but consult your doctor if you are unsure. Store the medicine in a cool, dry place away from direct sunlight and moisture. Keep it in your hand luggage rather than checked baggage to avoid loss or temperature extremes. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within the first few weeks, but noticeable weight loss usually takes several weeks to months when combined with diet and exercise. Your doctor will monitor your progress and adjust the dose as needed.
A: No, this medicine is not recommended during pregnancy. If you are pregnant or planning to become pregnant, talk to your doctor about alternative options.
A: If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, you should avoid alcohol while taking this medicine because it can increase the risk of seizures and liver problems.
A: No, you should not stop this medicine suddenly without talking to your doctor. Stopping suddenly can cause withdrawal symptoms or worsen underlying conditions.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is a magic pill for weight loss.
Fact: This medicine is not a magic pill. It works only when combined with a reduced-calorie diet and regular physical activity, and it is intended for people with obesity or overweight with weight-related conditions. - Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription-only medicine and must be started and monitored by a qualified healthcare professional. - Myth: This medicine is safe for everyone.
Fact: This medicine is not suitable for everyone. It is contraindicated in pregnancy, uncontrolled high blood pressure, seizure disorders, opioid dependence, and severe liver disease. - Myth: You can stop this medicine whenever you want.
Fact: You should not stop this medicine suddenly without talking to your doctor, as this can cause withdrawal symptoms or worsen underlying conditions.