Nempro P 100mg/325mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is nempro p 100mg/325mg tablet used for?
This medicine is a combination of aceclofenac and paracetamol used for short-term relief of acute pain and inflammation. It works by reducing prostaglandins that cause pain and swelling. Take it with food, avoid alcohol, and do not exceed the recommended dose.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nempro p 100mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिफेनाक और पैरासिटामोल का संयोजन है, जिसका उपयोग तीव्र दर्द और सूजन के इलाज के लिए किया जाता है। यह जोड़ों के दर्द, मांसपेशियों के दर्द, दांत दर्द, मासिक धर्म के दर्द और सर्जरी के बाद के दर्द में राहत देती है। यह दवा सूजन और दर्द पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। इसे भोजन के साथ लें और शराब से बचें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, उल्टी में खून, या गंभीर पेट दर्द हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट की जलन कम हो। शराब का सेवन न करें क्योंकि इससे रक्तस्राव और यकृत की क्षति का खतरा बढ़ सकता है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे, यकृत, या हृदय की समस्या है, तो डॉक्टर से सलाह लें। चक्कर आने पर वाहन न चलाएं।
💊 nempro p 100mg/325mg tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and low back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides effective relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after minor surgeries.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Reduces pain and improves joint function in osteoarthritis flare-ups.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps alleviate pain and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Fever","description":"May be used to reduce fever, though paracetamol alone is preferred.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Dysmenorrhea, Dental pain, Post-operative pain
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nempro p 100mg/325mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac, an NSAID, inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system, where it inhibits prostaglandin synthesis and may also modulate pain perception through other pathways. Together, they provide enhanced analgesic and anti-inflammatory effects.
Mechanism Steps
💡 How to Take nempro p 100mg/325mg tablet
Strength: Tablet containing aceclofenac 100 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally every 8 to 12 hours as needed for pain, not exceeding three tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Take with food to reduce stomach upset. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | Maximum of 3 tablets (aceclofenac 300 mg and paracetamol 975 mg) in 24 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nempro p 100mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- ACE inhibitors and ARBs
⚡ Moderate Interactions
- Diuretics
- Lithium
- SSRIs
- Antihypertensives
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, liver damage, and may worsen side effects such as dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to aceclofenac, paracetamol, or any component of the formulation","Active peptic ulcer or history of recurrent peptic ulcer","Severe heart failure","Severe kidney impairment","Severe liver impairment","Pregnancy (especially third trimester)","Breastfeeding","Children under 16 years of age"]
⚠️ Warnings & Precautions
["Take with food to reduce gastrointestinal irritation.","Avoid alcohol during treatment.","Do not exceed the recommended dose or duration.","Use with caution in elderly patients.","Use with caution in patients with asthma, as NSAIDs may trigger bronchospasm.","May impair ability to drive or operate machinery.","Consult doctor if symptoms persist beyond 7 days."]
🤱 Lactation Safety
Not recommended. Aceclofenac may pass into breast milk and could harm the infant. Paracetamol is considered safe during breastfeeding. Consult your doctor for alternatives.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, abdominal pain, drowsiness, and liver damage. Seek immediate medical attention. Treatment includes supportive care, activated charcoal if within 1-2 hours, and N-acetylcysteine for paracetamol toxicity. Monitor liver and kidney function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of gastrointestinal bleeding and liver damage. Do not take other pain relievers or NSAIDs without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Store this medicine at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester. If you are planning pregnancy or become pregnant while taking this medicine, consult your doctor immediately for alternative pain management options.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain relief as prescribed by your surgeon. Inform your surgeon about all medicines you are taking. Avoid alcohol and follow your surgeon's instructions regarding activity and diet.
🦷 Dental Procedures
This medicine can be used for dental pain and after dental procedures. Inform your dentist if you are taking this medicine, especially if you are scheduled for oral surgery, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may worsen pain while taking this medicine. Consult your doctor or physiotherapist for appropriate exercise modifications.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly interfere with daily activities when taken as prescribed.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your pain persists beyond 7 days, if you experience severe side effects, or if you develop signs of gastrointestinal bleeding, liver problems, or allergic reactions. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney problems, liver damage, and cardiovascular events. It is generally recommended for short-term use only. Regular monitoring of kidney and liver function may be required if used for extended periods. Consult your doctor for alternative treatments if long-term pain management is needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedMay help reduce pain and inflammation in localized areas.
Evidence: ModerateSome evidence for pain relief in certain conditions.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It is best taken with food or milk to reduce the risk of stomach upset.
A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as it may increase the risk of side effects.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is safe to take on an empty stomach.
Fact: It should be taken with food to reduce the risk of stomach upset and ulcers. - Myth: This medicine can be taken for any type of pain.
Fact: It is intended for specific types of pain and should only be used as prescribed. - Myth: More is better for faster relief.
Fact: Exceeding the dose can cause serious side effects and does not provide better relief.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 100 mg + Paracetamol 325 mg tablet