Nise 75mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is nelsid 75mg injection used for?
This medicine is a prescription injectable NSAID containing nimesulide 75 mg. It is used for short-term relief of moderate to severe acute pain and inflammation when oral therapy is not suitable. It works by blocking COX-2 enzymes. It must be given by a healthcare professional and is not for self-administration.
- Generic Name: Nimesulide (75mg)
- Manufacturer: Ind Swift Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nelsid 75mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा नाइमसुलाइड 75 मिलीग्राम इंजेक्शन है, जिसका उपयोग तीव्र दर्द और सूजन के इलाज के लिए किया जाता है। यह आमतौर पर ऑपरेशन के बाद के दर्द, मांसपेशियों के दर्द, गुर्दे की पथरी के दर्द और गठिया के दर्द में दिया जाता है। यह दवा सूजन पैदा करने वाले एंजाइम को रोककर काम करती है। यह केवल डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दी जाती है। इसे खुद से नहीं लगाना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, जी मिचलाना, उल्टी, पेट में जलन, दस्त, चक्कर आना और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में खून आना, गुर्दे की समस्या, लिवर की क्षति, गंभीर एलर्जी और दिल की समस्या हो सकती है। अगर ऐसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इसे खुद से न लगाएं। अपने डॉक्टर को अपनी सभी बीमारियों के बारे में बताएं, खासकर पेट के अल्सर, गुर्दे या लिवर की बीमारी, दिल की बीमारी, अस्थमा या खून से जुड़ी समस्या। इस दवा को लेते समय शराब न पिएं। बिना डॉक्टर की सलाह के 5 दिन से ज्यादा इसका इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर को जरूर बताएं।
💊 nelsid 75mg injection Uses & Benefits
[{"condition":"Acute moderate to severe pain","description":"This medicine is used for rapid relief of acute pain such as post-operative pain, musculoskeletal pain, or renal colic when oral NSAIDs are not suitable.","evidence":"Well-established"},{"condition":"Inflammatory conditions","description":"It helps reduce inflammation and pain in conditions like acute gout, rheumatoid arthritis flares, and soft tissue injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgical procedures when patients cannot take oral medications.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Fever unresponsive to other measures","description":"Rarely used off-label for fever when other treatments are ineffective, but not a first-line choice.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Post-operative pain, Musculoskeletal pain, Renal colic, Acute gout
📋 Drug Information
| Generic Name(s) | Nimesulide (75mg) |
| Brand Name | nelsid 75mg injection |
| Manufacturer | Ind Swift Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's-Non-Selective COX 1&2 Inhibitors (Others) |
| Route of Administration | Parenteral (intramuscular or intravenous injection) |
| Storage | Store in a cool, dry place below 25°C. Protect from light. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme, which is responsible for producing prostaglandins that mediate pain, inflammation, and fever. By blocking COX-2, it reduces the synthesis of these prostaglandins, leading to analgesic, anti-inflammatory, and antipyretic effects. Unlike non-selective NSAIDs, it has less effect on COX-1, which may reduce gastrointestinal side effects, but the risk is not eliminated, especially with injectable use.
Mechanism Steps
💡 How to Take nelsid 75mg injection
Strength: Injection: 75 mg in 1 ml or 2 ml ampoule/vial.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 75 mg given by intramuscular injection once or twice daily, depending on the severity of pain. The maximum recommended duration is 5 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use with caution and at the lowest effective dose. Monitor kidney and liver function closely. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction may be necessary. Avoid in severe kidney impairment. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction may be necessary. Avoid in severe liver impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 150 mg (two 75 mg injections). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nelsid 75mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Lithium | Moderate | |
| Methotrexate | Moderate | |
| Corticosteroids | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- ACE inhibitors and ARBs
- Diuretics
⚡ Moderate Interactions
- Lithium
- Methotrexate
- Corticosteroids
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine. Alcohol increases the risk of stomach bleeding and may worsen liver toxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to nimesulide or other NSAIDs","Active or history of peptic ulcer or gastrointestinal bleeding","Severe liver impairment","Severe kidney impairment","Severe heart failure","History of aspirin-sensitive asthma","Third trimester of pregnancy","Breastfeeding","Children under 12 years"]
⚠️ Warnings & Precautions
["Use the lowest effective dose for the shortest duration.","Avoid in patients with dehydration or hypovolemia.","Caution in elderly patients due to increased risk of side effects.","Monitor for signs of gastrointestinal bleeding.","Avoid concurrent use with other NSAIDs.","Use with caution in patients with hypertension or cardiovascular disease.","Do not use for more than 5 days without medical advice."]
🤱 Lactation Safety
Nimesulide is excreted in breast milk. It is not recommended during breastfeeding due to potential risks to the infant. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, abdominal pain, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. There is no specific antidote. Treatment is supportive and symptomatic. If overdose is suspected, seek immediate medical attention. Activated charcoal may be given if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
This medicine is usually given as a single dose or as directed by your doctor. If you miss a scheduled dose, contact your doctor or nurse for guidance. Do not attempt to self-administer an extra dose.
Additional Safety Advice
This medicine must be administered only by a healthcare professional in a clinical setting. Do not attempt to self-inject. Inform your doctor about all your medical conditions, especially stomach ulcers, kidney or liver disease, heart problems, asthma, or bleeding disorders. Also, tell your doctor about all other medicines you are taking, including blood thinners, other pain relievers, and blood pressure medications. Avoid alcohol while receiving this medicine as it increases the risk of stomach bleeding. Do not use this medicine for more than the recommended duration without medical advice. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor before receiving this medicine. Keep all follow-up appointments and report any unusual symptoms immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function closely. Avoid in patients with dehydration or pre-existing kidney disease.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended for women planning pregnancy or during pregnancy, especially in the third trimester, due to risk of fetal harm. Consult your doctor for alternative pain management options.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain management. It should be administered by a healthcare professional. Monitor for bleeding and kidney function, especially after major surgery.
🦷 Dental Procedures
This medicine may be used for pain relief after dental procedures. Inform your dentist about all medications you are taking. It is not a substitute for dental treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while receiving this medicine, especially if you have pain or inflammation. Gentle stretching and low-impact activities are recommended. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually given in a clinical setting, so you may need to arrange for transportation after the injection.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor immediately if you experience any serious side effects such as gastrointestinal bleeding, kidney problems, liver symptoms, or allergic reactions. Do not stop prescribed treatment without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to increased risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. It should only be used for short-term management of acute pain. Regular monitoring of kidney and liver function is advised if prolonged use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain management.
Evidence: Well-establishedMay help with certain types of pain.
Evidence: ModerateAlternative for localized pain with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
This medicine is an injectable prescription drug and should be carried only if prescribed by your doctor. Carry it in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling by air, keep it in your carry-on luggage with proper documentation. Check customs regulations of your destination country regarding injectable medications. Do not expose it to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts relieving pain within 15 to 30 minutes after injection.
A: The pain relief typically lasts for 6 to 8 hours.
A: It should be used with caution in kidney disease. Your doctor may adjust the dose or choose an alternative.
A: It is not recommended during pregnancy, especially in the third trimester. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for nelsid 75mg injection
View AllAlternative brands with exact same active ingredient:
-
Takeaway 75mg InjectionPanacea Biotec Ltd ₹14.02 14.3% COSTLIER
-
nise 75mg injectionDr Reddy's Laboratories Ltd ₹14.53 18.4% COSTLIER
-
nimulid safe 75mg injectionPanacea Biotec Ltd ₹15.94 29.9% COSTLIER
-
Nimujet 75mg InjectionThemis Medicare Ltd ₹15.96 30.1% COSTLIER
-
sumo 75 mg injectionAlkem Laboratories Ltd ₹98.21 700.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Nimesulide injection is safer than oral NSAIDs.
Fact: Injectable nimesulide carries the same risks as oral NSAIDs, including gastrointestinal, kidney, and liver toxicity. It is not safer. - Myth: Nimesulide injection can be taken for long-term pain.
Fact: It is only for short-term use, usually not more than 5 days, due to risk of serious side effects.
🔄 Alternative Options
Generic Alternatives
- Nimesulide 75 mg injection (generic)
Brand Alternatives
- Nise 75mg injection
- Nimulid 75mg injection
- Nimesulide 75mg injection