Nefrotag 500mg/150mg Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe dizziness or fainting
- Chest pain or irregular heartbeat
- Decreased urine output or swelling in the legs
- Yellowing of the skin or eyes
- Severe abdominal pain or vomiting blood
- Black or tarry stools
If experiencing severe symptoms, call emergency services immediately.
What is nefrotag 500mg/150mg tablet used for?
This medicine is a combination of telmisartan and amlodipine used to treat high blood pressure. It works by relaxing blood vessels and reducing fluid retention. It is taken once daily orally, usually with or without food. Do not stop taking it without consulting your doctor.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nefrotag 500mg/150mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। इसमें टेल्मिसार्टन और एम्लोडिपिन दो सक्रिय तत्व होते हैं जो रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करते हैं। यह उन रोगियों के लिए भी फायदेमंद हो सकती है जिन्हें किडनी की बीमारी और पेशाब में प्रोटीन की समस्या है। इस दवा को डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, पैरों में सूजन, थकान और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभावों में बहुत कम रक्तचाप, किडनी की समस्या, और एलर्जी प्रतिक्रिया शामिल हैं। अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, या बहुत ज्यादा चक्कर आए तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। बिना डॉक्टर की सलाह के दवा बंद न करें, भले ही आपको अच्छा महसूस हो। शराब न पिएं क्योंकि इससे चक्कर और कम रक्तचाप हो सकता है। गर्भवती महिलाओं को यह दवा नहीं लेनी चाहिए। अगर आपको किडनी या लीवर की बीमारी है तो डॉक्टर को बताएं। नियमित रूप से रक्तचाप और खून की जांच कराते रहें।
💊 nefrotag 500mg/150mg tablet Uses & Benefits
- [{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults when a single medicine is not enough.
- It helps reduce the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"},{"condition":"Diabetic nephropathy","description":"In patients with diabetes and high blood pressure, this medicine may help protect the kidneys by reducing protein leakage in the urine.","evidence":"Well-established"},{"condition":"Chronic kidney disease with proteinuria","description":"This medicine may be used to slow the progression of kidney disease in patients with protein in the urine, especially those with hypertension.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Heart failure with preserved ejection fraction","description":"Sometimes used off-label to manage blood pressure in patients with heart failure, but not a standard treatment.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Rarely used off-label for preventing migraines, but evidence is not strong.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Diabetic nephropathy, Chronic kidney disease with proteinuria
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nefrotag 500mg/150mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight and moisture. Do not refrigerate. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the AT1 receptor, preventing angiotensin II from causing vasoconstriction and aldosterone release. This leads to relaxation of blood vessels and reduced sodium and water retention. Amlodipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, causing peripheral arterial vasodilation and reduced peripheral resistance. The combined effect lowers blood pressure more effectively than either agent alone.
Mechanism Steps
💡 How to Take nefrotag 500mg/150mg tablet
Strength: Tablet containing telmisartan 40 mg and amlodipine 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, with or without food. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. The maximum recommended dose is one tablet of this strength per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dose adjustment is needed for mild to moderate renal impairment. In severe renal impairment or dialysis patients, use with caution and monitor kidney function and potassium levels. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, start with a lower dose and monitor closely. This medicine is contraindicated in severe hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | One tablet of this strength per day. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nefrotag 500mg/150mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| Spironolactone | Major | |
| Ibuprofen | Major | |
| Lithium | Major | |
| Ketoconazole | Moderate | |
| Rifampicin | Moderate | |
| Simvastatin | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor | |
| Beta-blockers | Moderate |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone)
- NSAIDs (e.g., ibuprofen)
- Lithium
- CYP3A4 inhibitors (e.g., ketoconazole)
⚡ Moderate Interactions
- CYP3A4 inducers (e.g., rifampicin)
- Beta-blockers
- Simvastatin
🍷 Alcohol Interaction
Alcohol may increase the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid alcohol or limit intake while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","Breastfeeding","History of angioedema with ARBs","Severe liver impairment or biliary obstruction","Severe aortic stenosis","Cardiogenic shock","Concomitant use with aliskiren in patients with diabetes"]
⚠️ Warnings & Precautions
["This medicine can cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use potassium supplements or salt substitutes without doctor's approval.","Monitor kidney function and potassium levels regularly.","Avoid alcohol while taking this medicine.","Inform your doctor if you have a history of kidney or liver disease.","Do not stop taking this medicine abruptly without consulting your doctor."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding because it may pass into breast milk and affect the baby. Consult your doctor for alternative treatments if you are breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe low blood pressure, dizziness, and fainting. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive, including intravenous fluids and monitoring of vital signs. Dialysis is not helpful for removing telmisartan or amlodipine from the body.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor, even if you feel well, because high blood pressure often has no symptoms. This medicine can cause dizziness, especially when you stand up quickly, so rise slowly from sitting or lying positions. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not take potassium supplements or salt substitutes containing potassium without your doctor's approval, as this medicine can increase potassium levels. Inform your doctor if you have kidney or liver problems, diabetes, or if you are dehydrated. Avoid alcohol while taking this medicine, as it can worsen dizziness and low blood pressure. If you are pregnant or planning to become pregnant, tell your doctor immediately, as this medicine can harm the unborn baby. Do not breastfeed while taking this medicine without consulting your doctor. Keep all appointments for blood pressure and blood test monitoring.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Regular monitoring of kidney function and electrolytes is advised.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception. Do not become pregnant while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid low blood pressure during the procedure. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause low blood pressure during dental procedures. Your dentist may take precautions and monitor your blood pressure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, avoid sudden strenuous activities, especially in hot weather, as they can cause dizziness or low blood pressure. Stay hydrated and rise slowly after exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work activities with caution. If you experience persistent dizziness or fatigue, consult your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like angioedema, severe dizziness, or kidney problems, contact your doctor immediately. Your doctor may adjust the dose or switch to a different medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing high blood pressure. Regular monitoring of blood pressure, kidney function, and potassium levels is important. In some patients, long-term use may lead to mild kidney function changes or electrolyte imbalances. Your doctor will adjust the dose or switch medicines if needed. Do not stop the medicine on your own.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help lower blood pressure and complement medicine.
Evidence: Well-establishedIf you cannot tolerate this combination, your doctor may prescribe a single antihypertensive medicine.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known with this medicine. However, consult your doctor before receiving any vaccine, especially if you have kidney disease or are on other medications.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue taking your dose at the same local time as much as possible. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but the full effect may take 1 to 2 weeks. Continue taking it regularly as prescribed.
A: Yes, you can take this medicine with or without food. If it upsets your stomach, take it with a meal.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, this medicine is not safe during pregnancy. It can harm the unborn baby. Inform your doctor immediately if you are pregnant or planning to become pregnant.
A: No, do not stop taking this medicine without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause a dangerous rise in blood pressure.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping the medicine can cause a dangerous rise in blood pressure. Always consult your doctor before stopping. - Myth: This medicine damages the kidneys.
Fact: This medicine is often used to protect the kidneys in patients with kidney disease and protein in the urine. Regular monitoring is important. - Myth: You can take extra doses if you miss one.
Fact: Taking a double dose can cause dangerously low blood pressure. Follow the missed dose instructions carefully.
🔄 Alternative Options
Generic Alternatives
- Telmisartan 40 mg + Amlodipine 5 mg tablet
Brand Alternatives
- Telma-AM 40/5
- Telmikind-AM 40/5
- Telmisartan-AM 40/5