Metadec 100mg Injection (nandrolone Decanoate): Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Chest pain, shortness of breath, or difficulty breathing
- Sudden weakness or numbness on one side of the body
- Severe abdominal pain with nausea and vomiting
- Yellowing of skin or eyes (jaundice)
- Dark urine or pale stools
- Swelling in legs or ankles
- Severe allergic reaction (rash, itching, swelling of face or throat)
If experiencing severe symptoms, call emergency services immediately.
What is ndl 100 injection used for?
This medicine is an anabolic steroid injection containing Nandrolone Decanoate 100 mg. It is used in specific medical conditions like anemia of chronic kidney disease and postmenopausal osteoporosis, but it is not a first-line treatment and carries significant risks. It must only be used under strict medical supervision.
- Generic Name: Nandrolone Decanoate (100mg)
- Manufacturer: Catholicon Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ndl 100 injection के बारे में (Hindi Summary)
उपयोग: यह दवा नैंड्रोलोन डेकानोएट 100 मिलीग्राम इंजेक्शन है, जो एक एनाबॉलिक स्टेरॉयड है। इसका उपयोग कुछ विशेष चिकित्सीय स्थितियों जैसे क्रोनिक किडनी रोग से जुड़े एनीमिया और पोस्टमेनोपॉज़ल ऑस्टियोपोरोसिस के इलाज में किया जाता है। यह दवा केवल डॉक्टर की सलाह पर ही ली जानी चाहिए और इसका दुरुपयोग शरीर सौष्ठव या खेल प्रदर्शन बढ़ाने के लिए नहीं किया जाना चाहिए। इसके गंभीर दुष्प्रभाव हो सकते हैं, इसलिए नियमित निगरानी आवश्यक है।
साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, सूजन, तरल पदार्थ का संचय, मुँहासे और यौन इच्छा में बदलाव शामिल हैं। गंभीर दुष्प्रभावों में रक्त के थक्के, दिल का दौरा, स्ट्रोक, यकृत विषाक्तता और एलर्जी प्रतिक्रियाएँ हो सकती हैं। महिलाओं में पुरुषत्व के लक्षण जैसे आवाज़ का भारी होना और चेहरे पर बाल आना हो सकता है।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं। यदि आपको हृदय रोग, यकृत रोग, गुर्दा रोग, उच्च रक्तचाप या मधुमेह है तो अपने डॉक्टर को बताएं। शराब से बचें क्योंकि इससे यकृत विषाक्तता का खतरा बढ़ता है। नियमित रूप से यकृत कार्य, रक्त गणना और लिपिड प्रोफाइल की निगरानी करवाएं। गर्भवती महिलाओं को यह दवा नहीं लेनी चाहिए।
💊 ndl 100 injection Uses & Benefits
[{"condition":"Anemia of chronic kidney disease","description":"This medicine can stimulate red blood cell production in patients with anemia due to chronic kidney disease, though it is not a first-line agent.","evidence":"Limited"},{"condition":"Anemia associated with cancer chemotherapy","description":"Sometimes used to treat anemia in cancer patients undergoing chemotherapy, but risks often outweigh benefits.","evidence":"Limited"},{"condition":"Postmenopausal osteoporosis","description":"In some countries, this medicine is approved for treating osteoporosis in postmenopausal women, but other treatments are preferred.","evidence":"Limited"},{"condition":"Hereditary angioedema","description":"Rarely used to prevent attacks of hereditary angioedema, but not a standard treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"HIV wasting syndrome","description":"Sometimes prescribed off-label to promote weight gain in patients with HIV-associated wasting, but evidence is limited and risks are significant.","evidence":"Limited"},{"condition":"Sarcopenia in elderly","description":"Occasionally used off-label to increase muscle mass in elderly patients, but not recommended due to cardiovascular risks.","evidence":"Limited"}]
Primary treatment for: Anemia of chronic kidney disease
Also treats: Postmenopausal osteoporosis, Hereditary angioedema, HIV wasting syndrome
📋 Drug Information
| Generic Name(s) | Nandrolone Decanoate (100mg) |
| Brand Name | ndl 100 injection |
| Manufacturer | Catholicon Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | HORMONES |
| Action Class | Anabolic steroid |
| Route of Administration | Parenteral (intramuscular injection) |
| Storage | Store at room temperature (15-30°C). Protect from light. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Nandrolone decanoate is an anabolic-androgenic steroid that binds to androgen receptors in target tissues. Upon binding, it translocates to the nucleus and modulates gene expression, leading to increased protein synthesis, muscle growth, and erythropoiesis. It also has some progestogenic activity and can suppress gonadotropin release, reducing endogenous testosterone production.
Mechanism Steps
💡 How to Take ndl 100 injection
Strength: 100 mg/mL injection
Dosage Information
| Adult Dosage | The dosage of this medicine must be individualized by a qualified clinician based on the indication, patient's age, weight, renal and hepatic function, and clinical response. For anemia of chronic kidney disease, a typical dose is 50-100 mg per week intramuscularly. For postmenopausal osteoporosis, 50 mg every 3 weeks is sometimes used. However, these are general references and not a substitute for professional medical advice. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to fluid retention and cardiovascular effects. Use with caution and monitor closely. |
| Renal Impairment | No specific dosage adjustments are established, but use with caution in patients with renal impairment due to risk of fluid retention and electrolyte imbalance. |
| Hepatic Impairment | Contraindicated in severe liver disease. In mild to moderate hepatic impairment, use with caution and monitor liver function closely. |
| Maximum Daily Dose | Not established from the available information. Dosing is individualized by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ndl 100 injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Insulin | Major | |
| Methotrexate | Major | |
| Corticosteroids | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Insulin and oral hypoglycemics
- Hepatotoxic drugs (e.g., methotrexate, acetaminophen)
⚡ Moderate Interactions
- Corticosteroids
- Cyclosporine
🍷 Alcohol Interaction
Alcohol should be avoided while using this medicine because it can increase the risk of liver damage and worsen fluid retention.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy or breastfeeding","Known hypersensitivity to nandrolone decanoate or any component","Male breast cancer or prostate cancer","Severe liver disease","Nephrotic syndrome","Hypercalcemia","History of cardiovascular disease"]
⚠️ Warnings & Precautions
["This medicine is a controlled substance and has a high potential for abuse.","Do not use for bodybuilding or athletic performance enhancement.","May cause virilization in women; discontinue if signs appear.","May suppress natural testosterone production and cause testicular atrophy.","Can cause fluid retention and worsen heart failure.","May increase risk of blood clots.","Regular monitoring of liver function, blood counts, and lipids is required.","Avoid alcohol consumption.","Do not share needles or syringes.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether nandrolone decanoate is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose with nandrolone decanoate is unlikely to cause acute severe symptoms due to its slow release. However, chronic overdose can lead to severe hormonal imbalances, liver toxicity, and cardiovascular events. Treatment is supportive and symptomatic. In case of suspected overdose, seek immediate medical attention.
⏰ Missed Dose
If you miss a dose, contact your healthcare provider for guidance. Do not double the dose to catch up.
Additional Safety Advice
This medicine must only be administered by a healthcare professional. Do not self-inject. Inform your doctor if you have heart disease, liver disease, kidney disease, high blood pressure, diabetes, or a history of blood clots. Regular monitoring of liver function, blood counts, and lipid profile is required. Avoid alcohol as it increases liver toxicity risk. Do not share needles or syringes. Women who are pregnant or may become pregnant must not handle or receive this medicine. Report any signs of liver problems (yellowing of eyes or skin, dark urine, abdominal pain) or heart problems (chest pain, shortness of breath, swelling in legs) immediately. Do not use this medicine for bodybuilding or athletic performance enhancement.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of cardiovascular events and fluid retention. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated in pregnancy and may cause birth defects. Women who are planning pregnancy should not use this medicine. Men using this medicine may experience reduced fertility; consult your doctor if you are planning to father a child.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine, as it may affect blood clotting and cardiovascular function during surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may affect bleeding and healing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Consult your doctor before starting any exercise program. Avoid strenuous activities if you have cardiovascular risk factors. Report any chest pain, shortness of breath, or swelling during exercise immediately.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some patients. Avoid driving or operating heavy machinery if you experience these effects. It may also affect mood and behavior; report any significant changes to your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as chest pain, difficulty breathing, or signs of liver problems, seek immediate medical attention. Your doctor may discontinue treatment if the risks outweigh the benefits.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to suppression of natural testosterone production, testicular atrophy, infertility, liver toxicity, cardiovascular disease, and dependence. Regular monitoring of liver function, lipid profile, and cardiovascular health is essential. Treatment should be reviewed periodically to assess the risk-benefit ratio.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For anemia of chronic kidney disease, ESAs are often preferred over anabolic steroids.
Evidence: Well-establishedFor postmenopausal osteoporosis, bisphosphonates are first-line treatments.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. This medicine is a controlled substance in many countries, so check local regulations before travel. Store it at room temperature and protect it from light. If traveling across time zones, consult your doctor about adjusting injection timing. Always carry enough supply for your trip and keep it in your carry-on luggage if flying.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Anabolic effects may take several weeks to become apparent. Your doctor will monitor your response.
A: It is given as an intramuscular injection by a healthcare professional.
A: Serious risks include blood clots, heart attack, stroke, and liver toxicity. Regular monitoring is required.
A: Women should use it only if clearly needed and under close supervision due to risk of virilization.
🤔 Common Patient Concerns
🔄 Substitutes for ndl 100 injection
View AllAlternative brands with exact same active ingredient:
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Todec 100mg InjectionLemford Biotech Pvt Ltd ₹140.63 48.3% CHEAPER
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deca-duralin 100mg injectionTaj Pharma India Ltd ₹151.27 44.4% CHEAPER
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rolanabol 100 injectionShree Venkatesh International Limited ₹158.06 41.9% CHEAPER
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dd 100 injectionAkme Biotec ₹158.44 41.7% CHEAPER
-
alidec 100 injectionAllenge India ₹168.00 38.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for bodybuilding.
Fact: This medicine is a prescription drug with serious risks and is not approved for bodybuilding or athletic performance enhancement. - Myth: This medicine has no side effects.
Fact: This medicine can cause serious side effects including liver toxicity, cardiovascular events, and hormonal imbalances. - Myth: This medicine is a vitamin or supplement.
Fact: This medicine is a potent anabolic steroid and a controlled substance, not a vitamin or supplement.
🔄 Alternative Options
Generic Alternatives
- Nandrolone Decanoate 100 mg injection (various manufacturers)
Brand Alternatives
- Metadec 100mg injection