Ndbolic 50mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of skin or eyes (jaundice)
- Severe abdominal pain or swelling
- Chest pain or shortness of breath
- Sudden weakness or difficulty speaking
- Blood in vomit or black tarry stools
- Decreased urine output or swelling in legs
- Severe allergic reaction with facial swelling
If experiencing severe symptoms, call emergency services immediately.
What is ndbolic 50mg injection used for?
This medicine is an injectable anabolic steroid containing nandrolone decanoate 50 mg. It is used under medical supervision for conditions like anaemia of chronic kidney disease and osteoporosis, but it carries serious risks including liver toxicity and cardiovascular events. It is not for bodybuilding and is contraindicated in pregnancy.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ndbolic 50mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा नैंड्रोलोन डेकानोएट नामक एनाबॉलिक स्टेरॉयड का इंजेक्शन है, जिसका उपयोग कुछ विशेष चिकित्सीय स्थितियों में किया जाता है। इसका मुख्य उपयोग क्रोनिक किडनी रोग से जुड़े एनीमिया, ऑस्टियोपोरोसिस, और कुछ कैटाबॉलिक या वेस्टिंग स्थितियों में किया जाता है। यह दवा शरीर में प्रोटीन संश्लेषण और लाल रक्त कोशिकाओं के उत्पादन को बढ़ावा देती है। यह दवा केवल डॉक्टर की सलाह पर और एक योग्य स्वास्थ्य पेशेवर द्वारा इंजेक्शन के रूप में दी जानी चाहिए। गर्भवती महिलाओं, स्तन कैंसर या प्रोस्टेट कैंसर वाले पुरुषों, और गंभीर यकृत या गुर्दे की बीमारी वाले रोगियों को यह दवा नहीं दी जानी चाहिए। इसका दुरुपयोग बॉडीबिल्डिंग के लिए करना खतरनाक और अवैध है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, सूजन, तरल पदार्थ का संचय, मुँहासे, और रक्तचाप में वृद्धि शामिल हैं। गंभीर दुष्प्रभावों में यकृत विषाक्तता, हृदयाघात, रक्त के थक्के, और पुरुषों में वृषण के आकार में कमी तथा स्तनों का बढ़ना शामिल हो सकता है। महिलाओं में आवाज भारी होना, चेहरे पर बाल आना, और मासिक धर्म में अनियमितता हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल एक योग्य स्वास्थ्य पेशेवर द्वारा इंट्रामस्क्युलर इंजेक्शन के रूप में दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं और न ही सुई साझा करें। उपचार के दौरान यकृत, गुर्दे, रक्त गणना, और लिपिड प्रोफाइल की नियमित निगरानी आवश्यक है। इस दवा का सेवन करते समय शराब से बचें। यदि आपको हृदय रोग, यकृत रोग, गुर्दे की बीमारी, प्रोस्टेट समस्या, या रक्त के थक्के की समस्या है तो अपने डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाओं को यह दवा नहीं लेनी चाहिए। खेलों में इसका उपयोग प्रतिबंधित है। डॉक्टर की सलाह के बिना खुराक न बढ़ाएं।
💊 ndbolic 50mg injection Uses & Benefits
[{"condition":"Anaemia of chronic kidney disease","description":"This medicine can stimulate erythropoiesis and improve haemoglobin levels in some patients with anaemia associated with chronic kidney disease, though it is not a first-line treatment.","evidence":"Limited"},{"condition":"Osteoporosis in postmenopausal women","description":"This medicine may be used as an adjunct to increase bone mineral density in selected postmenopausal women with osteoporosis, but it is not a standard first-line therapy.","evidence":"Limited"},{"condition":"Catabolic or wasting conditions","description":"This medicine may be prescribed to promote weight gain and muscle mass in patients with severe catabolic states, such as after major surgery, trauma, or chronic infections, but evidence is limited.","evidence":"Limited"},{"condition":"Hereditary angioedema","description":"This medicine has been used off-label to prevent attacks of hereditary angioedema by increasing levels of C1 esterase inhibitor, but it is not a standard treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"HIV wasting syndrome","description":"Sometimes used off-label to promote weight gain in patients with HIV-associated wasting, but it is not a standard therapy and carries risks.","evidence":"Limited"},{"condition":"Male hypogonadism","description":"Occasionally used off-label for testosterone replacement in hypogonadal men, but it is not a preferred agent due to side effects and legal restrictions.","evidence":"Limited"}]
Primary treatment for: Anaemia of chronic kidney disease
Also treats: Osteoporosis, Catabolic states, Hereditary angioedema
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | ndbolic 50mg injection |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | HORMONES |
| Action Class | Anabolic steroid |
| Route of Administration | Parenteral (intramuscular injection) |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and freezing. Keep in the original container. |
| Shelf Life | The shelf life is typically 24 to 36 months from the date of manufacture, but refer to the product label for the exact expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a synthetic anabolic-androgenic steroid that binds to cytoplasmic androgen receptors in target tissues. Upon binding, the receptor-ligand complex translocates to the nucleus and modulates gene transcription, leading to increased protein synthesis, nitrogen retention, and erythropoietin production. It also has progestogenic activity and can suppress gonadotropin secretion, reducing endogenous testosterone production.
Mechanism Steps
💡 How to Take ndbolic 50mg injection
Strength: 50 mg injection (nandrolone decanoate 50 mg/mL)
Dosage Information
| Adult Dosage | The dosage of this medicine must be individualized by a qualified clinician based on the indication, patient's age, weight, renal and hepatic function, and clinical response. For anaemia of chronic kidney disease, a typical adult dose is 50 to 100 mg intramuscularly once weekly, but this may vary. For osteoporosis, doses of 50 mg every 3 to 4 weeks have been used. Always follow your doctor's prescription exactly. Do not self-administer or change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to fluid retention, cardiovascular effects, and liver toxicity. Use with caution and monitor closely. Dose adjustment may be necessary based on renal and hepatic function. |
| Renal Impairment | This medicine should be used with caution in patients with renal impairment. Dose reduction may be required, and renal function should be monitored regularly. Consult your doctor for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in severe liver disease. In mild to moderate hepatic impairment, use with caution and monitor liver function closely. Dose adjustment may be necessary. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Doses are typically given weekly or every few weeks, not daily. Follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ndbolic 50mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Insulin | Major | |
| Corticosteroids | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Hepatotoxic drugs (e.g., methotrexate, isoniazid)
- Insulin and oral hypoglycemics
⚡ Moderate Interactions
- Corticosteroids
- Cyclosporine
🍷 Alcohol Interaction
Alcohol should be avoided while using this medicine because both can stress the liver and increase the risk of liver toxicity. Alcohol may also worsen fluid retention and blood pressure elevation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy or breastfeeding","Known hypersensitivity to nandrolone or any component","Male breast cancer or prostate cancer","Severe liver disease","Severe kidney disease","Hypercalcaemia","Nephrotic syndrome","History of myocardial infarction or heart failure"]
⚠️ Warnings & Precautions
["This medicine is for intramuscular use only and must be administered by a healthcare professional.","Do not use for bodybuilding or athletic performance enhancement; it is illegal and dangerous.","May cause virilization in women; discontinue if signs appear.","May suppress endogenous testosterone and cause infertility in men.","Can worsen heart failure and cause fluid retention; use with caution in cardiac patients.","May increase risk of blood clots; monitor for thromboembolic events.","Regular monitoring of liver, kidney, and blood parameters is required.","Avoid alcohol and other hepatotoxic drugs.","Not for use in children; pediatric safety and efficacy not established.","May impair ability to drive or operate machinery if dizziness occurs."]
🤱 Lactation Safety
This medicine is excreted in breast milk and may cause serious adverse effects in a nursing infant. Breastfeeding is not recommended while using this medicine.
💊 Overdose Management
Overdose with this medicine is unlikely due to its injectable route and medical supervision. If accidental overdose occurs, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Monitor vital signs, liver function, and cardiovascular status.
⏰ Missed Dose
If you miss a scheduled dose of this medicine, contact your healthcare provider as soon as possible. Do not attempt to self-administer a double dose. Your doctor will advise on the next appropriate dose and schedule.
Additional Safety Advice
This medicine must only be administered by a healthcare professional as an intramuscular injection. Do not self-administer or share needles. Regular monitoring of liver function, kidney function, blood counts, and lipid profile is essential during treatment. Avoid alcohol and other liver-damaging substances while using this medicine. Inform your doctor if you have a history of heart disease, liver disease, kidney disease, prostate problems, or blood clotting disorders. This medicine is not for use in pregnant or breastfeeding women. It is banned in competitive sports, and its non-medical use can lead to serious health consequences and legal penalties. Never increase the dose or frequency without your doctor's approval. Keep all follow-up appointments and report any new or worsening symptoms promptly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of fluid retention, cardiovascular events, and liver toxicity. Use with caution, monitor closely, and adjust doses based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated in pregnancy and should not be used by women planning to become pregnant. It can cause fetal harm. Discuss alternative treatments with your doctor if you are planning pregnancy.
🏥 Post-Surgery Considerations
This medicine may be used in some post-surgical catabolic states, but it can increase the risk of blood clots. Your surgeon and doctor will determine if it is appropriate for you.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may affect bleeding risk and wound healing. Your dentist may consult with your doctor before performing any procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While using this medicine, avoid strenuous or high-impact exercises that could strain your heart or joints. Consult your doctor before starting any new exercise regimen. If you experience chest pain, shortness of breath, or dizziness during exercise, stop immediately and seek medical attention.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, fatigue, or mood changes that could affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as jaundice, chest pain, severe allergic reaction, or signs of virilization, seek immediate medical attention and your doctor will decide whether to discontinue treatment.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to liver toxicity, including peliosis hepatis and liver tumours, cardiovascular complications such as hypertension and heart failure, and endocrine effects like suppression of natural testosterone production and infertility. Regular monitoring of liver function, lipid profile, and cardiovascular status is essential. The risk-benefit ratio should be reassessed periodically.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For anaemia of chronic kidney disease, ESAs are often preferred over anabolic steroids.
Evidence: Well-establishedFor osteoporosis, bisphosphonates are first-line and have a better safety profile.
Evidence: Well-establishedFor catabolic states, optimizing nutrition and treating underlying causes is essential.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, consult your doctor before receiving any live vaccines while on immunosuppressive therapy.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Check expiry date before use
❌ DON'T
Do not use if expired or discolored
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label. Bring a copy of your prescription and a letter from your doctor explaining the medical need. Keep it in carry-on luggage to avoid temperature extremes. Check customs regulations for controlled substances in your destination country. Store at room temperature and protect from light. If crossing time zones, consult your doctor about adjusting injection timing.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects of this medicine are gradual. It may take 1 to 2 weeks for initial effects and several weeks for full benefits, depending on the condition being treated.
A: No, this medicine is contraindicated in pregnancy as it can harm the fetus. Inform your doctor immediately if you become pregnant.
A: Long-term use requires careful monitoring due to risks of liver toxicity, cardiovascular events, and hormonal imbalances. Your doctor will determine the appropriate duration.
A: No, this medicine is not approved for bodybuilding and its non-medical use is illegal and dangerous.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is safe for bodybuilding.
Fact: This medicine is a prescription anabolic steroid with serious health risks and is illegal for non-medical use. - Myth: This medicine can be self-administered.
Fact: It must only be given by a healthcare professional as an intramuscular injection. - Myth: This medicine has no long-term side effects.
Fact: Long-term use can cause liver damage, heart problems, and hormonal imbalances.
🔄 Alternative Options
Generic Alternatives
- Nandrolone decanoate 50 mg injection
Brand Alternatives
- ndbolic 50mg injection