nax gel - Allantoin (0.1% w/w) + Clindamycin (1% w/w) medicine

Nax Gel: Complete Guide To Uses, Side Effects, And Safety

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🏭 Galcare Pharmaceutical Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Nov 1, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for topical clindamycin in acne; limited for the combination with allantoin.
Reviewed by
SaathiMed Expert Panel | Nov 01, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe or persistent diarrhea
  • Blood in stool or vomit
  • Severe abdominal pain or cramps
  • Swelling of face, lips, or throat
  • Difficulty breathing
  • Widespread rash or blistering of skin
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is nax gel used for?

This medicine is a topical gel containing allantoin 0.1% and clindamycin 1%. It is used to treat acne and minor skin infections by reducing bacteria and soothing the skin. Apply a thin layer to the affected area as directed by your doctor.

  • Generic Name: Allantoin (0.1% w/w) + Clindamycin (1% w/w)
  • Manufacturer: Galcare Pharmaceutical Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nax gel के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल जेल है जिसमें एलांटोइन 0.1% और क्लिंडामाइसिन 1% होता है। इसका उपयोग मुँहासे (एक्ने) और त्वचा के छोटे संक्रमणों के इलाज के लिए किया जाता है। क्लिंडामाइसिन बैक्टीरिया को मारता है और एलांटोइन त्वचा को शांत और ठीक करने में मदद करता है। इसे डॉक्टर के निर्देशानुसार प्रभावित त्वचा पर पतली परत में लगाएं।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में त्वचा का सूखना, खुजली, लालिमा, जलन या परत छूटना शामिल है। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर दस्त, पेट दर्द, या चेहरे, होंठ या गले में सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को केवल प्रभावित त्वचा पर ही लगाएं। आंखों, होंठों और मुँह के संपर्क में न आने दें। लगाने से पहले और बाद में हाथ धोएं। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें। दवा को डॉक्टर के बताए अनुसार ही इस्तेमाल करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 nax gel Uses & Benefits

[{"condition":"Inflammatory acne vulgaris","description":"This medicine helps reduce acne lesions by decreasing the bacteria Cutibacterium acnes and promoting skin healing through allantoin.","evidence":"Well-established for topical clindamycin; allantoin is a supportive agent."},{"condition":"Minor skin infections with bacterial component","description":"May be used to treat small superficial skin infections where clindamycin-sensitive bacteria are involved, while allantoin soothes the skin.","evidence":"Limited, based on clinical judgment."},{"condition":"Skin irritation with secondary bacterial overgrowth","description":"Allantoin helps calm and soften irritated skin, while clindamycin targets any associated bacterial overgrowth.","evidence":"Limited, anecdotal."}]

Off-label uses: [{"condition":"Rosacea with inflammatory papules","description":"Sometimes prescribed off-label for rosacea that has a bacterial component, though not FDA-approved for this use.","evidence":"Limited"},{"condition":"Hidradenitis suppurativa (mild)","description":"Topical clindamycin is occasionally used off-label for mild hidradenitis suppurativa, but allantoin's role is not established.","evidence":"Limited"}]

Primary treatment for: Acne vulgaris

Also treats: Minor skin infections, Skin irritation with bacterial overgrowth

📋 Drug Information

Generic Name(s)Allantoin (0.1% w/w) + Clindamycin (1% w/w)
Brand Namenax gel
ManufacturerGalcare Pharmaceutical Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore at room temperature between 15°C and 30°C. Keep away from direct sunlight and moisture. Do not freeze.
Shelf Life24 months from the date of manufacture, unless otherwise stated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine to clean, dry skin for best results.
2
Use a pea-sized amount for the entire face if treating acne.
3
Avoid using harsh soaps or scrubs that can irritate your skin.
4
If your skin becomes too dry, use a gentle, non-comedogenic moisturizer.
5
Do not stop using this medicine as soon as acne improves; complete the course as advised.
6
If you develop severe diarrhea, stop using this medicine and contact your doctor immediately.
7
Keep the gel away from your eyes, lips, and nose.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Acne pimples
This medicine is commonly prescribed for acne.
Likely Use
✅
Minor skin infection
May be used for small infected cuts or abrasions.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Severe skin rash
Consult a doctor; this medicine may not be appropriate.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClindamycin is absorbed through the skin to a limited extent after topical application. Systemic absorption is generally low but can increase if the medicine is applied to large areas of broken or inflamed skin. Allantoin is minimally absorbed through intact skin.
DistributionNot established from the available information for the topical combination. Systemically absorbed clindamycin is known to distribute widely into body fluids and tissues, but this is not typically relevant for topical use.
Protein BindingClindamycin is approximately 90% bound to plasma proteins when it reaches the bloodstream. Protein binding of allantoin is not established.
MetabolismClindamycin is metabolized in the liver, primarily by cytochrome P450 enzymes, to active and inactive metabolites. Allantoin is not significantly metabolized.
Half-LifeThe elimination half-life of clindamycin is approximately 2 to 3 hours when absorbed systemically. The half-life of allantoin is not established.
ExcretionClindamycin and its metabolites are excreted mainly in the urine and bile. Allantoin is excreted unchanged in the urine.
BioavailabilityThe systemic bioavailability of clindamycin after topical application is low, typically less than 5% of the applied dose, but may increase with damaged skin. Bioavailability of allantoin is not established.
Onset of ActionImprovement in acne lesions may begin within 2 to 4 weeks of regular use, but noticeable results often take 6 to 8 weeks. The soothing effect of allantoin may be felt sooner.
Peak Plasma TimeNot established from the available information for topical use.
Duration of ActionThe antibacterial effect of clindamycin lasts for several hours after application, but the clinical effect builds with consistent use over weeks. Allantoin's soothing effect is temporary and requires reapplication.

How It Works

This medicine combines two active ingredients with different but complementary actions. Clindamycin is a lincosamide antibiotic that binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. This reduces the population of Cutibacterium acnes and other clindamycin-sensitive organisms on the skin. Allantoin is a skin protectant that promotes cell proliferation, enhances the shedding of dead skin cells, and helps to soothe and soften the skin. Together, they reduce bacterial load and support skin healing, which helps to improve acne and minor skin irritations.

Mechanism Steps

1
Clindamycin binds to bacterial ribosomes: Clindamycin attaches to the 50S subunit of the bacterial ribosome, blocking the early steps of protein synthesis.
2
Inhibition of bacterial protein synthesis: This prevents bacteria from building essential proteins, which stops their growth and multiplication.
3
Reduction of Cutibacterium acnes: The decreased bacterial population reduces the inflammatory response in acne lesions.
4
Allantoin promotes skin healing: Allantoin softens the skin, encourages the removal of dead cells, and supports the regeneration of healthy skin.
5
Combined effect: The antibacterial action of clindamycin and the soothing action of allantoin work together to clear acne and calm irritated skin.

💡 How to Take nax gel

Strength: Gel containing allantoin 0.1% w/w and clindamycin 1% w/w.

1Wash your hands thoroughly before applying the gel.
2Clean and dry the affected skin area gently.
3Apply a thin layer of the gel to the affected area.
4Rub it in gently until it disappears.
5Wash your hands after application.
6Avoid contact with eyes, lips, and mucous membranes.
7Use as directed by your doctor, usually once or twice daily.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected skin area once or twice daily, or as directed by your doctor. Clean and dry the skin before application. The dose and frequency must be individualized by a qualified clinician based on the severity of your condition, your age, and your response to treatment. Do not use more than prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate use in children.
Elderly DosageElderly patients can generally use this medicine as directed by a doctor. However, they may be more prone to skin dryness and irritation, so monitor for these effects.
Renal ImpairmentNo dosage adjustment is typically needed for topical use in patients with kidney disease. However, consult your doctor if you have severe kidney impairment.
Hepatic ImpairmentNo dosage adjustment is typically needed for topical use in patients with liver disease. Consult your doctor if you have severe liver impairment.
Maximum Daily DoseThe maximum daily dose depends on the area being treated and the frequency prescribed. Do not exceed the recommended application frequency. For topical use, the amount should be enough to cover the affected area with a thin layer.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of nax gel

✅ Common Side Effects

Dryness or peeling of skin (Common (up to 10%))
Apply a gentle moisturizer if needed. If severe, reduce frequency or consult your doctor.
Itching or redness at application site (Common (5-10%))
Usually resolves with continued use. If it persists or worsens, stop and consult your doctor.
Burning or stinging sensation (Common (5-10%))
This often lessens after a few applications. If it is severe, discontinue and seek medical advice.
Oily skin (Uncommon (1-5%))
Use a gentle cleanser. Consult your doctor if it becomes bothersome.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, or throat, difficulty breathing, or a widespread rash.
Pseudomembranous colitis (Rare (<0.1%))
Stop using this medicine and contact your doctor right away if you develop severe or persistent diarrhea, abdominal cramps, or fever.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Seek immediate medical attention if you notice a painful rash, blistering, or peeling of the skin.

⚠️ Rare Side Effects

Bloody diarrhea
Seek immediate medical attention.
Severe abdominal pain
Consult a doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Neuromuscular blocking agents Major
Erythromycin Major
Benzoyl peroxide Moderate
Salicylic acid Moderate
Retinoids (topical) Moderate
Alcohol-containing skincare Minor

🚨 Major Interactions

  • Neuromuscular blocking agents (e.g., vecuronium)
  • Erythromycin

⚡ Moderate Interactions

  • Other topical acne products (e.g., benzoyl peroxide, salicylic acid, retinoids)
  • Kaolin-pectin antidiarrheal

🍷 Alcohol Interaction

There is no known direct interaction between this topical medicine and alcohol. However, drinking alcohol may worsen acne or skin inflammation in some people. It is best to limit alcohol intake while treating acne.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to clindamycin, lincomycin, or any component of the gel","History of regional enteritis, ulcerative colitis, or antibiotic-associated colitis","Use on large areas of broken or damaged skin without medical supervision","Use in the eyes, mouth, or nose"]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes, lips, and mucous membranes.","Do not apply to large areas of broken skin.","Stop use and consult a doctor if severe diarrhea develops.","Use with caution in patients with a history of gastrointestinal disease, especially colitis.","Do not use for prolonged periods without medical supervision, as it may lead to antibiotic resistance.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether clindamycin or allantoin passes into breast milk in significant amounts after topical application. To be safe, avoid applying this medicine to the breast area, and consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose from topical application is unlikely. If excessive amounts are applied, wash the area thoroughly with water. If the medicine is accidentally swallowed, seek medical attention immediately. Symptoms of oral overdose may include nausea, vomiting, and diarrhea.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply this medicine only to the affected areas of your skin, using a thin layer as directed by your doctor. Wash your hands thoroughly before and after applying the gel. Avoid contact with your eyes, lips, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with cool water. Do not cover the treated area with tight bandages or dressings unless your doctor tells you to. Avoid using other skin products that may dry or irritate your skin, such as harsh soaps, alcohol-based cleansers, or abrasive scrubs, unless approved by your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Keep this medicine out of the reach of children. If your acne does not improve after several weeks of consistent use, or if it worsens, consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have more sensitive skin and are more prone to dryness and irritation. Use with caution and monitor for side effects. No dosage adjustment is typically needed.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Topical clindamycin is generally considered safe, but your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before applying this medicine to the surgical area. It is usually safe to use on other areas of skin.

🦷 Dental Procedures

This medicine is for topical use and does not affect dental procedures. However, inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Wash your face gently twice daily with a mild cleanser.
🥗
Avoid picking or squeezing acne lesions to prevent scarring.
😴
Use oil-free, non-comedogenic skincare and makeup products.
💧
Maintain a balanced diet and stay hydrated.
🧘
Manage stress through relaxation techniques, as stress can worsen acne.
🌞
Get adequate sleep to support skin health.

🏋️ Exercise Considerations

You can exercise while using this medicine. However, sweat may irritate the skin, so wash your face gently after exercising and reapply if necessary. Avoid sharing towels or equipment that may spread bacteria.

🥗 Diet Recommendations

Include plenty of fruits and vegetables rich in antioxidants.
Limit high-glycemic foods that may worsen acne.
Stay well hydrated by drinking adequate water.
Consider omega-3 fatty acids from fish or flaxseed for skin health.

💼 Impact on Daily Work & Life

This medicine does not affect your ability to drive or operate machinery. It may cause mild skin irritation, but this usually does not interfere with daily activities. You can continue your normal work and social life.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if you experience severe skin irritation, allergic reactions, or severe diarrhea. Do not stop abruptly if you are using it for acne without consulting your doctor, as acne may flare up.

📅 Long-Term Use Effects

Long-term use of topical clindamycin may lead to bacterial resistance, reducing its effectiveness. It is important to use it only as prescribed and for the recommended duration. Rarely, prolonged use can increase the risk of pseudomembranous colitis. Regular follow-up with your doctor is advised to monitor progress and adjust treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Benzoyl peroxide

An alternative topical treatment for acne that kills bacteria and helps unclog pores.

Evidence: Well-established
Salicylic acid

A beta-hydroxy acid that helps exfoliate and unclog pores.

Evidence: Well-established
Retinoids

Prescription topical retinoids can be effective for acne but may cause irritation.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If you are flying, keep it in your carry-on bag if you need it during the flight. For international travel, check local customs regulations regarding prescription medicines. Continue your regular application schedule, adjusting for time zones if necessary.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 22-year-old college student with moderate acne
She was prescribed this medicine for her acne. She applied it twice daily after washing her face. After 4 weeks, she noticed fewer pimples and less redness. She experienced mild dryness, which was managed with a moisturizer.
💡 Lesson: Consistent use and gentle skincare can improve acne without severe side effects.
👤 A 35-year-old man with minor skin infection
He had a small infected cut on his arm. His doctor recommended this medicine. He applied it as directed and kept the area clean. The infection cleared within a week, and the allantoin helped soothe the skin.
💡 Lesson: This medicine can effectively treat minor skin infections when used as prescribed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start seeing improvement in 2 to 4 weeks, but it can take 6 to 8 weeks for full effect. Consistent use is important.

Q: Can I use moisturizer with this medicine?

A: Yes, you can use a gentle, non-comedogenic moisturizer if your skin feels dry. Apply the medicine first, then moisturizer.

Q: Is it safe to use during pregnancy?

A: Topical clindamycin is generally considered safe during pregnancy, but consult your doctor before use.

Q: What should I do if I get severe diarrhea?

A: Stop using this medicine and contact your doctor immediately, as it could be a sign of a serious bowel condition.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine long-term?
  • Will it make my skin dry?
  • Can I wear makeup while using this medicine?
  • Does it interact with my other skincare products?
  • What if I miss a dose?
  • Can I use it on my back and chest?

🛑 Myths vs. Facts

  • Myth: This medicine works overnight.
    Fact: Acne treatments take weeks to show improvement. Consistent use is key.
  • Myth: You can stop using it once acne clears.
    Fact: Stopping too soon may cause acne to return. Follow your doctor's advice.
  • Myth: More application means faster results.
    Fact: Applying more than directed can increase irritation without speeding up results.

🔄 Alternative Options

Generic Alternatives

  • Clindamycin 1% gel
  • Allantoin 0.1% gel

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredient":"Allantoin 0.1% + Clindamycin 1%","primary_use":"Acne, minor skin infections","route":"Topical"},{"medicine":"Clindamycin 1% gel","active_ingredient":"Clindamycin 1%","primary_use":"Acne","route":"Topical"},{"medicine":"Erythromycin 2% gel","active_ingredient":"Erythromycin 2%","primary_use":"Acne","route":"Topical"}]

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