dermatrax 7.5mg tablet
What is dermatrax 7.5mg tablet used for?
AuraTrex 5mg Tablet (Methotrexate) is used to treat ANTI NEOPLASTICS. It contains Methotrexate (7.5mg), which Inhibits dihydrofolate reductase (DHFR), blocking tetrahydrofolate synthesis and. Always consult your doctor before use. Take as prescribed.
- Generic Name: Methotrexate
- Manufacturer: Galcare Pharmaceutical Pvt Ltd
- Form: Allopathy
- Pregnancy Category: X
- Prescription Required: Yes
๐ dermatrax 7.5mg tablet Uses & Benefits
Acute lymphoblastic leukemia, rheumatoid arthritis, psoriasis, ectopic pregnancy, osteosarcoma, non-Hodgkin lymphoma, breast cancer, head and neck cancer, lung cancer, bladder cancer, mycosis fungoides.
Off-label uses: Sarcoidosis, systemic lupus erythematosus, dermatomyositis, Crohn's disease, graft-versus-host disease, multiple sclerosis, vasculitis, uveitis, ectopic pregnancy (non-surgical management).
๐ Drug Information
| Generic Name(s) | Methotrexate |
| Brand Name | AuraTrex 5mg Tablet |
| Manufacturer | Galcare Pharmaceutical Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolite- Methotrexate |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits dihydrofolate reductase (DHFR), blocking tetrahydrofolate synthesis and DNA synthesis.
Mechanism Steps
๐ก How to Take dermatrax 7.5mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of dermatrax 7.5mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Stomatitis
- Mucositis
- Fatigue
- Alopecia
- Anorexia
- Elevated liver enzymes
- Leukopenia
- Thrombocytopenia
- Anemia
๐จ Serious Side Effects
- Myelosuppression
- Hepatotoxicity
- Nephrotoxicity
- Pulmonary fibrosis
- Pneumonitis
- Severe infections
- Tumor lysis syndrome
- Gastrointestinal perforation
- Neurotoxicity (leukoencephalopathy)
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Lymphoma
- Osteoporosis
- Photosensitivity
- Acute uric acid nephropathy
- Pancreatitis
- Pericarditis
- Pleural effusion
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| NSAIDs | Major | Increased methotrexate toxicity (myelosuppression, nephrotoxicity) |
| Probenecid | Major | Decreased renal excretion, increased toxicity |
| Salicylates | Major | Displacement from protein binding, increased toxicity |
| Sulfonamides | Major | Additive antifolate effect |
| Phenytoin | Major | Decreased phenytoin levels |
| Retinoids | Major | Increased hepatotoxicity |
| Penicillins | Moderate | Decreased methotrexate clearance |
| Cephalosporins | Moderate | Decreased methotrexate clearance |
| Omeprazole | Moderate | Delayed methotrexate elimination |
| Theophylline | Moderate | Increased theophylline levels |
| Folic acid | Moderate | Reduced methotrexate efficacy |
| Antacids | Minor | Decreased absorption |
| Cholestyramine | Minor | Decreased absorption |
| Digoxin | Minor | Decreased digoxin levels |
๐จ Major Interactions
- NSAIDs
- Probenecid
- Salicylates
- Sulfonamides
- Phenytoin
- Retinoids
โก Moderate Interactions
- Penicillins
- Cephalosporins
- Omeprazole
- Theophylline
- Folic acid
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Digoxin
๐ฝ๏ธ Food Interactions
Food may delay absorption; high-fat meals reduce peak concentration.
๐ท Alcohol Interaction
Increased hepatotoxicity risk; avoid alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Pregnancy, breastfeeding, severe renal impairment, severe hepatic impairment, alcoholism, immunodeficiency syndromes, pre-existing blood dyscrasias.
๐ Monitoring Parameters
CBC with differential, liver function tests, renal function tests, methotrexate serum levels, chest X-ray, pulmonary function tests.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Administer leucovorin (folinic acid) as soon as possible; hydration and alkalinization of urine; consider charcoal hemoperfusion.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for dermatrax 7.5mg tablet
View AllAlternative brands with exact same active ingredient (Methotrexate (7.5mg)):
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mexate 7.5 mg injectionZydus Cadila โน30.00 70% CHEAPER
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davaindia methotrexate 7.5mg tabletDavaindia Generic Pharmacy โน35.00 64.9% CHEAPER
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auratrex 7.5mg tabletAbbott โน47.20 52.7% CHEAPER
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folitrax 7.5mg injectionIpca Laboratories Ltd โน56.10 43.8% CHEAPER
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ethitrex 7.5 tabletEthicare Remedies โน85.00 14.9% CHEAPER
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imutaj 7.5mg tabletTaj Pharma India Ltd โน87.00 12.9% CHEAPER
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mecan 7.5 tabletCanbro Healthcare โน97.00 2.9% CHEAPER
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mtx 7.5mg tabletNexgen Rx Life Science Pvt Ltd โน97.50 2.4% CHEAPER
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methate 7.5mg tabletRace Pharmaceuticals pvt ltd โน100.00 0.2% COSTLIER
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psoriax 7.5 tabletCannote Healthcare โน103.00 3.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Helpful and effective medicine as per my experience. Always consult a doctor.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.