Nasrel Tablet: Complete Guide To Uses, Dosage, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe dizziness or fainting
- Fast, irregular, or pounding heartbeat
- Inability to urinate or severe lower abdominal pain
- Confusion, hallucinations, or seizures
- Yellowing of the skin or eyes
- Severe rash or hives
If experiencing severe symptoms, call emergency services immediately.
What is nasrel tablet used for?
This medicine is a combination of Caffeine and Chlorpheniramine Maleate used to relieve allergy and cold symptoms such as sneezing, runny nose, and watery eyes. Chlorpheniramine is an antihistamine that reduces allergic reactions, while Caffeine helps reduce drowsiness caused by the antihistamine. It is usually taken every 4 to 6 hours as needed, but not more than 6 tablets in 24 hours. It may cause drowsiness, so avoid driving or alcohol.
- Generic Name: Caffeine (16mg) + Chlorpheniramine Maleate (2gm)
- Manufacturer: Cinerea Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nasrel tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कैफीन और क्लोरफेनिरामाइन मेलिएट का संयोजन है, जिसका उपयोग एलर्जी और सर्दी-जुकाम के लक्षणों जैसे छींक आना, नाक बहना, आंखों में खुजली और पानी आना आदि में राहत के लिए किया जाता है। क्लोरफेनिरामाइन एक एंटीहिस्टामिन है जो एलर्जी प्रतिक्रिया को कम करता है, जबकि कैफीन नींद और सुस्ती को कम करने में मदद करता है। यह दवा आमतौर पर हर 4 से 6 घंटे में एक गोली के रूप में ली जाती है, लेकिन 24 घंटे में 6 गोलियों से अधिक नहीं लेनी चाहिए। इस दवा से नींद आ सकती है, इसलिए गाड़ी चलाने या शराब पीने से बचें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, धुंधली दृष्टि, मतली और बेचैनी शामिल हैं। कैफीन के कारण कुछ लोगों को अनिद्रा या घबराहट हो सकती है। दुर्लभ मामलों में गंभीर एलर्जी प्रतिक्रिया, दिल की धड़कन तेज होना, पेशाब रुकना, भ्रम या दौरे पड़ सकते हैं। यदि कोई भी दुष्प्रभाव गंभीर हो या लंबे समय तक बना रहे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। निर्धारित मात्रा से अधिक न लें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक गाड़ी चलाने या मशीन चलाने से बचें। शराब या अन्य नींद लाने वाली दवाओं के साथ इसका सेवन न करें। यदि आपको ग्लूकोमा, प्रोस्टेट की समस्या, पेशाब में कठिनाई, हृदय रोग, उच्च रक्तचाप, या लीवर/किडनी की बीमारी है, तो डॉक्टर को बताएं। बिना सलाह के लंबे समय तक इसका उपयोग न करें। बच्चों की पहुंच से दूर रखें।
💊 nasrel tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal itching associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of sneezing, runny nose, and nasal congestion, while caffeine helps reduce associated fatigue.","evidence":"Established for symptomatic relief"},{"condition":"Allergic conjunctivitis","description":"Helps reduce itching, redness, and tearing of the eyes due to allergic reactions.","evidence":"Limited"},{"condition":"Urticaria","description":"May help control itching and hives as an adjunct to other treatments.","evidence":"Limited"}]
Off-label uses: [{"condition":"Motion sickness","description":"Sometimes used off-label for mild motion sickness due to antihistamine effects, but not a first-line option.","evidence":"Limited"},{"condition":"Insomnia due to shift work","description":"Not recommended; the caffeine content can worsen sleep problems.","evidence":"Not established from the available information."}]
Primary treatment for: Allergic rhinitis
Also treats: Common cold, Allergic conjunctivitis, Urticaria
📋 Drug Information
| Generic Name(s) | Caffeine (16mg) + Chlorpheniramine Maleate (2gm) |
| Brand Name | nasrel tablet |
| Manufacturer | Cinerea Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors on effector cells, thereby reducing vascular permeability, itching, sneezing, and mucus secretion associated with allergic reactions. It also crosses the blood-brain barrier and causes sedation by blocking central H1 receptors. Caffeine is a methylxanthine that acts as a central nervous system stimulant by antagonizing adenosine A1 and A2A receptors, which increases alertness and reduces fatigue. The combination is designed to provide allergy symptom relief while partially offsetting the sedative effect of the antihistamine.
Mechanism Steps
💡 How to Take nasrel tablet
Strength: Each immediate-release tablet contains Caffeine 16 mg and Chlorpheniramine Maleate 2 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 4 to 6 hours as needed for symptoms, not to exceed 6 tablets in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to treatment. Do not self-medicate or exceed the recommended dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the sedative and anticholinergic effects of chlorpheniramine. Use with caution and consider a lower dose as recommended by a clinician. |
| Renal Impairment | Dose adjustment may be necessary in patients with renal impairment. Consult a doctor for personalized dosing. |
| Hepatic Impairment | Dose adjustment may be necessary in patients with hepatic impairment. Consult a doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 6 tablets in 24 hours for adults. Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nasrel tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Tricyclic antidepressants | Moderate | |
| Fluoxetine | Moderate | |
| Ciprofloxacin | Moderate | |
| Antacids | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Alcohol
- Other CNS depressants (e.g., benzodiazepines, opioids, sedatives)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- CYP1A2 inhibitors (e.g., ciprofloxacin, fluvoxamine)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair your ability to concentrate and react. Combining alcohol with chlorpheniramine can also increase the risk of severe sedation and respiratory depression.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to chlorpheniramine, caffeine, or any component of the formulation","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Severe liver disease","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOI","Breastfeeding without medical advice"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, prostatic hypertrophy, or difficulty urinating.","Use with caution in patients with cardiovascular disease, hypertension, or hyperthyroidism.","Do not exceed the recommended dose.","Not recommended for children under 12 years without medical advice.","Consult a doctor if symptoms persist beyond 7 days or are accompanied by fever.","Keep out of reach of children."]
🤱 Lactation Safety
Chlorpheniramine Maleate and Caffeine are excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, agitation, confusion, hallucinations, seizures, irregular heartbeat, and difficulty breathing. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid consuming alcohol or other central nervous system depressants while taking this medicine because they can increase drowsiness and impair your ability to think clearly. Inform your doctor if you have glaucoma, an enlarged prostate, difficulty urinating, thyroid problems, heart disease, high blood pressure, or liver or kidney disease. Do not use this medicine for longer than directed without medical advice. Keep out of reach of children. Store at room temperature away from moisture and heat. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of chlorpheniramine. They may also be more prone to urinary retention and confusion. Use with caution and consider lower doses as advised by a doctor.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with anesthetics and other medications. It may also increase the risk of urinary retention post-operatively.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it can cause dry mouth and may interact with sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities that require alertness until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It may also cause insomnia if taken late in the day, impacting sleep and work performance. Plan your doses accordingly and inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance to the stimulant effect and increased sedation. Prolonged use of antihistamines can cause dry mouth, constipation, and urinary retention. Regular monitoring by a doctor is advised if used for more than 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Identifying and avoiding triggers can reduce the need for medication.
Evidence: Well-establishedHelps clear nasal passages and reduce congestion.
Evidence: Well-establishedOptions like cetirizine or loratadine cause less sedation.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccination timing while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking it as needed for symptoms, but avoid taking it close to bedtime to prevent insomnia. Check customs regulations for carrying medications across borders.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking a dose.
A: It may cause insomnia due to the caffeine content. It is best to take it earlier in the day unless your doctor advises otherwise.
A: Do not take with other antihistamines without consulting your doctor, as it may increase side effects.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure allergies permanently.
Fact: This medicine only provides symptomatic relief and does not cure the underlying allergy. - Myth: It is safe to take this medicine with alcohol.
Fact: Alcohol increases drowsiness and CNS depression; it should be avoided. - Myth: More tablets will work faster.
Fact: Taking more than the recommended dose can cause serious side effects and does not improve efficacy.
🔄 Alternative Options
Generic Alternatives
- Caffeine + Chlorpheniramine Maleate tablets